Abstract:
OBJECTIVE:To present a report on assisted reproductive technologies (ART) cycles performed in 2005 in Canada. This is the fifth annual report from the Canadian ART Register (CARTR). DESIGN:Prospective cohort study. SETTING:Twenty-five of 25 ART centers in Canada. PARTICIPANT(S):Couples undergoing ART treatment in Canada during 2005. INTERVENTION(S):ART treatments, including IVF, intracytoplasmic sperm injection (ICSI), and frozen ET (FET). MAIN OUTCOME MEASURE(S):Clinical pregnancy, live birth, and multiple birth rates. RESULT(S):A total of 11,414 ART cycles was reported to CARTR. In 8195 IVF/ICSI cycles using the women's own oocytes, the clinical pregnancy rate per cycle started was 32.1% (37.5% per ET procedure), and the live birth rate was 25.6%; the multiple birth rate per delivery was 30.8%, with a triplet birth rate of 1.4%. IVF was performed in 40% of cycles and ICSI in 60% with similar pregnancy rates. One or two embryos were transferred in 68% of cycles; transferring more embryos did not increase the pregnancy rate. In 301 IVF/ICSI cycles using donor oocytes, the clinical pregnancy rate was 46.5%, and the live birth rate was 35.2%; the multiple birth rate was 33.3%, with no triplet birth. In 2498 FET cycles using the woman's own oocytes, the clinical pregnancy rate was 22.8%, and the live birth rate was 17.4%; the multiple birth rate was 24.5%, with a triplet birth rate of 1.6%. Compared with singletons, babies from multiple births had higher risks for preterm birth, low birth weight, and perinatal death. CONCLUSION(S):For 2005, CARTR achieved 100% voluntary participation from Canadian ART centers for the third consecutive year. Clinical pregnancy and live birth rates continued to increase in 2005 compared with previous years.
journal_name
Fertil Steriljournal_title
Fertility and sterilityauthors
Gunby J,Bissonnette F,Librach C,Cowan L,IVF Directors Group of the Canadian Fertility and Andrology Society.doi
10.1016/j.fertnstert.2008.02.125subject
Has Abstractpub_date
2009-05-01 00:00:00pages
1721-30issue
5eissn
0015-0282issn
1556-5653pii
S0015-0282(08)00493-7journal_volume
91pub_type
杂志文章abstract::Sequential treatment with clomiphene citrate, human menopausal gonadotropin, and human chorionic gonadotropin was successfully applied to 149 women in the framework of an in vitro fertilization and embryo transfer program and led to the birth of normal children. An average of 3.5 follicles was promoted at each cycle. ...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(16)48382-2
更新日期:1985-02-01 00:00:00
abstract:OBJECTIVE:To evaluate the expression of type IV collagen [alpha1(IV) to alpha6(IV)] in testes and the association with spermatogenesis. DESIGN:Retrospective immunohistochemical study. SETTING:Division of Urology, Department of Organs Therapeutics, Faculty of Medicine, in a university hospital. PATIENT(S):Testicular ...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(03)00775-1
更新日期:2003-09-01 00:00:00
abstract:OBJECTIVE:To describe trends in age-specific incidence rates of female sterilization (FS) procedures in Western Australia and to evaluate the effects of the introduction of government-subsidized contraceptive methods and the implementation of the Australian government's baby bonus policy on FS rates. DESIGN:Population...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2016.04.035
更新日期:2016-09-01 00:00:00
abstract:OBJECTIVE:To determine the incidence of ovarian hyperstimulation syndrome (OHSS) in a large series of GnRH antagonist-stimulated cycles and to assess the predictive value of E2 and the number of follicles on the day of hCG administration. DESIGN:Prospective cohort study of women undergoing IVF treatment with a GnRH an...
journal_title:Fertility and sterility
pub_type: 临床试验,杂志文章
doi:10.1016/j.fertnstert.2005.07.1292
更新日期:2006-01-01 00:00:00
abstract:OBJECTIVE:To investigate the utility of random anti-Müllerian hormone (AMH) in assessing ovarian response among women with diminished ovarian reserve (DOR) diagnosed by elevated early follicular-phase FSH levels. DESIGN:Retrospective study. SETTING:Academic and academically affiliated assisted reproductive technology...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2011.03.071
更新日期:2011-06-01 00:00:00
abstract:OBJECTIVE:To determine the proportion of infertile women who prefer a multiple birth over a singleton, patient characteristics associated with this desire, and patient knowledge about the risks of multiple births. DESIGN:Prospective analysis. SETTING:Academic university hospital-based infertility center and private g...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2003.05.035
更新日期:2004-03-01 00:00:00
abstract::In a rat model, sodium carboxymethylcellulose (SCMC) was compared with normal saline and 32% dextran 70 in the prevention of surgically induced intraperitoneal adhesions. The 32% dextran 70 was similar to normal saline in the initial prevention of adhesions, and both appeared less effective than SCMC. After lysis of t...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(16)47910-0
更新日期:1984-06-01 00:00:00
abstract:OBJECTIVE:To evaluate the plasma asymmetric dimethyl arginine (ADMA) levels and carotid intima-media thickness (IMT) in patients with polycystic ovary syndrome (PCOS). DESIGN:Prospective study. SETTING:University medical center. PATIENT(S):Thirty-five patients with PCOS and 31 healthy controls. INTERVENTION(S):Peri...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2008.10.073
更新日期:2010-03-01 00:00:00
abstract::Heterologous antibodies have frequently been used to develop assays in other species. Human urinary LH kits, widely available for predicting the LH surge, offer a unique opportunity to determine the timing of ovulation and mating in nonhuman primates. We tested three commercially available ovulation predictor kits for...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(16)53301-9
更新日期:1990-02-01 00:00:00
abstract:OBJECTIVE:To determine the effect of human sperm incubation at room temperature (20 degrees C) upon capacitation-related events. DESIGN:Prospective study. SETTING:Basic research laboratory. PATIENT(S):Semen samples were obtained from normozoospermic volunteers. Human follicular fluid (hFF) was collected from women u...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(01)02982-x
更新日期:2002-02-01 00:00:00
abstract::U. urealyticum with 15.8% and C. trachomatis antibodies with 15.4% were the most prevalent microbiological findings in 209 male infertility patients. The inflammatory marker granulocyte-elastase was significantly increased in men with C. trachomatis; these men also showed significantly decreased citric acid levels ind...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(16)54318-0
更新日期:1991-05-01 00:00:00
abstract:OBJECTIVES:To study the effect of GnRH agonist (GnRH-a) treatment on memory and to assess the role of psychological factors. DESIGN:A randomized prospective study. SETTING:An academic teaching hospital. PARTICIPANTS:Women with endometriosis and infertility or endometriosis alone. MAIN OUTCOME MEASURES:Memory Observ...
journal_title:Fertility and sterility
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/s0015-0282(16)58351-4
更新日期:1996-06-01 00:00:00
abstract:OBJECTIVE:To report preterm birth and small for gestational age (SGA) rates from assisted reproduction technologies (ART) patients with ovarian endometriomata compared with control groups. DESIGN:Retrospective cohort study. SETTING:Tertiary university affiliated ART center and Perinatal Data Collection Unit (PDCU). ...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2008.01.096
更新日期:2009-02-01 00:00:00
abstract:OBJECTIVE:To determine whether high levels of interleukin (IL)-10 can attenuate the production of tumor necrosis factor (TNF)-alpha-induced proinflammatory cytokines in endometriotic stromal cells. DESIGN:Prospective study. SETTING:Department of Ob/Gyn, Tottori University, Japan. PATIENT(S):Thirty-five patients with...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2008.04.052
更新日期:2009-05-01 00:00:00
abstract::To evaluate the effectiveness of intravenous metoclopramide, alone or in combination with luteinizing hormone-releasing hormone (LH-RH), in distinguishing between constitutional delay of puberty and hypogonadotropic hypogonadism, 12 patients with constitutional delay of puberty and 10 patients with hypogonadotropic hy...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(16)60788-4
更新日期:1989-07-01 00:00:00
abstract::This document provides a general overview for physicians of the qualities and conditions necessary for good management practices within the endocrinology, andrology, and embryology laboratories in the United States. It is intended as an addendum to previously published guidelines that further detail these responsibili...
journal_title:Fertility and sterility
pub_type: 杂志文章,实务指引,评审
doi:10.1016/j.fertnstert.2014.06.036
更新日期:2014-10-01 00:00:00
abstract:OBJECTIVE:To test the hypothesis that adrenal androgen (AA) secretion is an inherited trait in PCOS and that serum DHEAS concentrations, as a marker of AA secretion, will be correlated between women with PCOS and their sisters. DESIGN:Prospective case-control. SETTING:Tertiary care center. PATIENT(S):Sixty-two PCOS ...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2006.05.045
更新日期:2006-12-01 00:00:00
abstract:OBJECTIVE:To evaluate the association between leiomyomas and estrogen receptor gene polymorphism. DESIGN:Prospective study. SETTING:Department of gynecology and genetics. PATIENT(S):Women with (n = 159) or without leiomyomas (n = 131). MAIN OUTCOME MEASURE(S):Polymerase chain reaction was used to detect dinucleotid...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(02)04563-6
更新日期:2003-01-01 00:00:00
abstract:OBJECTIVE:To compare danazol and gestrinone treatment as preoperative endometrial preparation for operative hysteroscopy. DESIGN:Prospective, randomized clinical study. SETTING:University department of gynecological, obstetrical sciences and reproductive medicine. PATIENT(S):One hundred thirty-five patients with end...
journal_title:Fertility and sterility
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.fertnstert.2005.09.034
更新日期:2006-04-01 00:00:00
abstract::Serum anti-Müllerian hormone concentrations vary significantly over time and this should be taken into account when tailoring treatment protocols for patients undergoing controlled ovarian hyperstimulation (COH). Compared with FSH, serum anti-Müllerian hormone may have greater discriminatory power because of its modes...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2010.10.001
更新日期:2011-03-01 00:00:00
abstract:OBJECTIVE:To study the fusiogenic ability of human spermatozoa and oocytes. DESIGN:Retrospective study of 3,027 oocytes included in a program of subzonal insemination (SUZI). SETTING:Assisted fertilization program in an academic research environment. PATIENT(S):Couples with characterized male factor infertility or p...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(97)81445-8
更新日期:1997-06-01 00:00:00
abstract:OBJECTIVE:The aim of this article is to summarize the recommended updates to the 2001 Stages of Reproductive Aging Workshop (STRAW) criteria. The 2011 STRAW + 10 reviewed advances in understanding of the critical changes in hypothalamic-pituitary-ovarian function that occur before and after the final menstrual period. ...
journal_title:Fertility and sterility
pub_type: 共识发展会议,杂志文章,实务指引
doi:10.1016/j.fertnstert.2012.01.128
更新日期:2012-04-01 00:00:00
abstract::The purpose of this article is to appraise the literature to ascertain whether the use of bariatric surgery should have a role in the contemporary management of the morbidly obese infertile patient before proceeding with infertility treatment. ...
journal_title:Fertility and sterility
pub_type: 杂志文章,meta分析,评审
doi:10.1016/j.fertnstert.2006.07.1499
更新日期:2007-02-01 00:00:00
abstract:OBJECTIVE:To describe the molecular, cytogenetic, immunohistochemical, and endocrinologic characteristics of a young 46,XY female with persistent müllerian structures and germ cell tumors in dysgenetic gonads. DESIGN:Descriptive case study. SETTING:Mackay Memorial Hospital and National Yang-Ming University, Taipei, T...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(99)00169-7
更新日期:1999-07-01 00:00:00
abstract::It is suggested that heparin given in the peri-implantation period may improve clinical outcomes in women undergoing assisted reproduction techniques (ART). This systematic review evaluates the use of heparin in subfertile women undergoing ART. ...
journal_title:Fertility and sterility
pub_type: 杂志文章,meta分析,评审
doi:10.1016/j.fertnstert.2014.09.005
更新日期:2015-01-01 00:00:00
abstract:OBJECTIVE:To study the correlation between indices of air pollution and sperm parameters. DESIGN:Ecological study. SETTING:Contained geographic area. PATIENT(S):Resident men presenting for semen analysis or artificial insemination. INTERVENTION(S):Analysis of levels of particulate air pollution (particulate matter ...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2008.12.089
更新日期:2010-04-01 00:00:00
abstract::Many studies evaluating a possible relationship between inherited thrombophilia and the etiology of unexplained infertility have been performed recently. No significant difference in the prevalence of three genetic mutations associated with the increased risk of thrombophilia (Factor V Leiden G1691A, prothrombin G2021...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2009.10.014
更新日期:2010-07-01 00:00:00
abstract:OBJECTIVE:To assess the expression and cellular distribution of angiotensin II (Ang II), angiotensin type 1 receptor (AT1R), angiotensin-converting enzyme (ACE), aminopeptidase A (APA), adipocyte-derived leucine aminopeptidase (A-LAP), and vascular endothelial growth factor (VEGF) in human ovarian tissue during the men...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2006.01.041
更新日期:2006-08-01 00:00:00
abstract::Menopausal hormone therapy (HT) has complex biologic effects but continues to have an important clinical role in the management of vasomotor and other menopausal symptoms. The rational use of menopausal HT requires balancing the potential benefits and risks of treatment. Findings from the Women's Health Initiative (WH...
journal_title:Fertility and sterility
pub_type: 杂志文章,评审
doi:10.1016/j.fertnstert.2014.02.043
更新日期:2014-04-01 00:00:00
abstract:OBJECTIVE:To determine whether patients who failed an in vitro fertilization (IVF) cycle can proceed with a subsequent IVF cycle after waiting only one menstrual cycle, or whether there is a benefit to allowing two or more menstrual cycles to elapse before proceeding. DESIGN:Retrospective cohort study. SETTING:Academ...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2012.11.044
更新日期:2013-04-01 00:00:00