Preterm birth, ovarian endometriomata, and assisted reproduction technologies.

Abstract:

OBJECTIVE:To report preterm birth and small for gestational age (SGA) rates from assisted reproduction technologies (ART) patients with ovarian endometriomata compared with control groups. DESIGN:Retrospective cohort study. SETTING:Tertiary university affiliated ART center and Perinatal Data Collection Unit (PDCU). PATIENT(S):Every woman who had an ART singleton baby born between 1991 and 2004 had her database record assessed (N = 4382). Control groups included 1201 singleton babies from ART patients without endometriosis and 2400 randomly selected women from the PDCU database of 850,000 births. INTERVENTION(S):There were 95 singleton ART babies from patients with ovarian endometriomata and 535 ART singleton babies from patients who had endometriosis but no ovarian endometriomata. MAIN OUTCOME MEASURE(S):Preterm birth rates and SGA birth rates. RESULT(S):Preterm birth rate increased only in the ovarian endometriomata group when compared with community birth records (n = 850,000). Furthermore, ART patients with ovarian endometriomata had a statistically significantly increased likelihood of having a SGA baby when compared with other forms of endometriosis. CONCLUSION(S):Rates of preterm birth and SGA babies doubled in infertility patients with ovarian endometriomata who required ART.

journal_name

Fertil Steril

journal_title

Fertility and sterility

authors

Fernando S,Breheny S,Jaques AM,Halliday JL,Baker G,Healy D

doi

10.1016/j.fertnstert.2008.01.096

subject

Has Abstract

pub_date

2009-02-01 00:00:00

pages

325-30

issue

2

eissn

0015-0282

issn

1556-5653

pii

S0015-0282(08)00195-7

journal_volume

91

pub_type

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