Abstract:
:This meta-analysis explores the location and function of brain areas involved in social cognition, or the capacity to understand people's behavioral intentions, social beliefs, and personality traits. On the basis of over 200 fMRI studies, it tests alternative theoretical proposals that attempt to explain how several brain areas process information relevant for social cognition. The results suggest that inferring temporary states such as goals, intentions, and desires of other people-even when they are false and unjust from our own perspective--strongly engages the temporo-parietal junction (TPJ). Inferring more enduring dispositions of others and the self, or interpersonal norms and scripts, engages the medial prefrontal cortex (mPFC), although temporal states can also activate the mPFC. Other candidate tasks reflecting general-purpose brain processes that may potentially subserve social cognition are briefly reviewed, such as sequence learning, causality detection, emotion processing, and executive functioning (action monitoring, attention, dual task monitoring, episodic memory retrieval), but none of them overlaps uniquely with the regions activated during social cognition. Hence, it appears that social cognition particularly engages the TPJ and mPFC regions. The available evidence is consistent with the role of a TPJ-related mirror system for inferring temporary goals and intentions at a relatively perceptual level of representation, and the mPFC as a module that integrates social information across time and allows reflection and representation of traits and norms, and presumably also of intentionality, at a more abstract cognitive level.
journal_name
Hum Brain Mappjournal_title
Human brain mappingauthors
Van Overwalle Fdoi
10.1002/hbm.20547subject
Has Abstractpub_date
2009-03-01 00:00:00pages
829-58issue
3eissn
1065-9471issn
1097-0193journal_volume
30pub_type
杂志文章,meta分析abstract::The Disrupted in Schizophrenia Gene 1 (DISC1) plays a role in both neural signaling and development and is associated with schizophrenia, although its links to altered brain structure and function in this disorder are not fully established. Here we have used structural and functional MRI to investigate links with six ...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.22560
更新日期:2014-11-01 00:00:00
abstract::We continuously perceive objects in the world through multiple sensory channels. In this study, we investigated the convergence of information from different sensory streams within the cerebral cortex. We presented volunteers with three common objects via three different modalities-sight, sound, and touch-and used mul...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.22867
更新日期:2015-09-01 00:00:00
abstract:BACKGROUND:Trait impulsiveness is a potential factor that predicts both substance use and certain psychiatric disorders. This study investigates whether there are common structural cerebral correlates of trait impulsiveness and cognitive functioning in a large sample of healthy adolescents from the IMAGEN project. MET...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.21446
更新日期:2013-02-01 00:00:00
abstract::There is a great individual variability for acquiring syntactic knowledge in a second language (L2). Little is, however, known if there is any anatomical basis in the brain for individual differences in syntactic acquisition. Here we examined brain structures in 95 nonnative speakers of English, including 78 high-scho...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.20790
更新日期:2009-11-01 00:00:00
abstract::The use of functional magnetic resonance imaging (fMRI) to explore central auditory function may be compromised by the intense bursts of stray acoustic noise produced by the scanner whenever the magnetic resonance signal is read out. We present results evaluating the use of one method to reduce the effect of the scann...
journal_title:Human brain mapping
pub_type: 临床试验,杂志文章
doi:10.1002/(sici)1097-0193(1999)7:3<213::aid-hbm5>3.0
更新日期:1999-01-01 00:00:00
abstract::The human gustatory cortex analyzes the chemosensory properties of tastants, particularly the quality, intensity, and affective valence, to determine whether a perceived substance should be ingested or rejected. Among previous studies, the spatial distribution of taste intensity-related activations within the human in...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.24621
更新日期:2019-08-15 00:00:00
abstract::Working memory (WM) for auditory information has been thought of as a unitary system, but whether WM for verbal and tonal information relies on the same or different functional neuroarchitectures has remained unknown. This fMRI study examines verbal and tonal WM in both nonmusicians (who are trained in speech, but not...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.21060
更新日期:2011-05-01 00:00:00
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journal_title:Human brain mapping
pub_type: 杂志文章,评审
doi:10.1002/hbm.22623
更新日期:2015-01-01 00:00:00
abstract::Patients with schizophrenia have patterns of brain deficits including reduced cortical thickness, subcortical gray matter volumes, and cerebral white matter integrity. We proposed the regional vulnerability index (RVI) to translate the results of Enhancing Neuro Imaging Genetics Meta-Analysis studies to the individual...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.25045
更新日期:2020-05-28 00:00:00
abstract::Previous studies exploring the neural substrates of executive functioning used task-specific analyses, which might not be the most appropriate approach due to the difficulty of precisely isolating executive functions. Consequently, the aim of this study was to use positron emission tomography (PET) to reexamine by con...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.20118
更新日期:2005-08-01 00:00:00
abstract::A subgroup of Parkinson's disease (PD) patients treated with dopaminergic therapy develop compulsive reward-driven behaviors, which can result in life-altering morbidity. The mesocorticolimbic dopamine network guides reward-motivated behavior; however, its role in this treatment-related behavioral phenotype is incompl...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.23860
更新日期:2018-01-01 00:00:00
abstract::Variability quenching is a widespread neural phenomenon in which trial-to-trial variability (TTV) of neural activity is reduced by repeated presentations of a sensory stimulus. However, its neural mechanism and functional significance remain poorly understood. Recurrent network dynamics are suggested as a candidate me...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.24304
更新日期:2018-11-01 00:00:00
abstract::Extensive efforts are devoted to understand the functional (FC) and structural connections (SC) of the brain. FC is usually measured by functional magnetic resonance imaging (fMRI), and conceptualized as degree of synchronicity in brain activity between different regions. SC is typically indexed by measures of white m...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.23403
更新日期:2017-01-01 00:00:00
abstract::An important function of the brain's orienting response is to enable the evaluation of novel, environmental events in order to prepare for potential behavioral action. Here, we assessed the event-related hemodynamic (erfMRI) correlates of this phenomenon using unexpected (i.e., novel) environmental sounds presented wi...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.20587
更新日期:2009-04-01 00:00:00
abstract::The neurobiological basis of reading is of considerable interest, yet analyzing data from subjects reading words aloud during functional MRI data collection can be difficult. Therefore, many investigators use surrogate tasks such as visual matching or rhyme matching to eliminate the need for spoken output. Use of thes...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.22077
更新日期:2013-10-01 00:00:00
abstract::The effect of stimulus modulation rate on the underlying neural activity in human auditory cortex is not clear. Human studies (using both invasive and noninvasive techniques) have demonstrated that at the population level, auditory cortex follows stimulus envelope. Here we examined the effect of stimulus modulation ra...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.21100
更新日期:2011-08-01 00:00:00
abstract::Sedation has a graded effect on brain responses to auditory stimuli: perceptual processing persists at sedation levels that attenuate more complex processing. We used fMRI in healthy volunteers sedated with propofol to assess changes in neural responses to spoken stimuli. Volunteers were scanned awake, sedated, and du...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.22375
更新日期:2014-07-01 00:00:00
abstract::Puberty represents the phase of sexual maturity, signaling the change from childhood into adulthood. During childhood and adolescence, prominent changes take place in the brain. Recently, variation in frontal, temporal, and parietal areas was found to be under varying genetic control between 5 and 19 years of age. How...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.20660
更新日期:2009-07-01 00:00:00
abstract::Electrophysiological signals recorded intracranially show rich frequency content spanning from near-DC to hundreds of hertz. Noninvasive electromagnetic signals measured with electroencephalography (EEG) or magnetoencephalography (MEG) typically contain less signal power in high frequencies than invasive recordings. P...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.24795
更新日期:2020-01-01 00:00:00
abstract::The neural basis of the automatic activation of words was investigated in an fMRI study. In the study, words were presented briefly (51 or 151 msec) followed by a mask. To prevent attentional processing, subjects attended to the masks and not the words, and were required to make perceptual judgment about the masks. We...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.10096
更新日期:2003-03-01 00:00:00
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journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.24704
更新日期:2019-10-15 00:00:00
abstract::Voluntary movements require control of multiple kinematic parameters, a task carried out by a distributed brain architecture. However, it remains unclear whether regions along the motor system encode single, or rather a mixture of, kinematic parameters during action execution. Here, rapid event-related functional magn...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.23802
更新日期:2017-12-01 00:00:00
abstract::White matter (WM) microstructure, as determined by diffusion tensor imaging (DTI), is increasingly recognized as an important determinant of cognitive function and is also altered in neuropsychiatric disorders. Little is known about genetic and environmental influences on WM microstructure, especially in early childho...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.24436
更新日期:2019-03-01 00:00:00
abstract::Research using the Stop Signal Task employing an adaptive algorithm to accommodate individual differences often report inferior performance on the task in individuals with ADHD, OCD, and substance use disorders compared to non-clinical controls. Furthermore, individuals with deficits in inhibitory control tend to show...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.24075
更新日期:2018-08-01 00:00:00
abstract::The brain seeks to combine related inputs from different senses (e.g., hearing and vision), via multisensory integration. Temporal information can indicate whether stimuli in different senses are related or not. A recent human fMRI study (Noesselt et al. [2007]: J Neurosci 27:11431-11441) used auditory and visual trai...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.21278
更新日期:2012-05-01 00:00:00
abstract::It has recently been demonstrated that specific patterns of correlation exist in diffusion tensor imaging (DTI) parameters across white matter tracts in the normal human brain. These microstructural correlations are thought to reflect phylogenetic and functional similarities between different axonal fiber pathways. Ho...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.21292
更新日期:2012-06-01 00:00:00
abstract::Previous studies showed that neurons in the monkey premotor cortex became active when performing a particular action and also when observing the same action performed by others. These findings suggest a mirror system for action observation. Recently, bimodal neurons, sensitive both to visual and tactile stimulation, w...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.20701
更新日期:2009-09-01 00:00:00
abstract::Fluent readers process written text rapidly and accurately, and comprehend what they read. Historically, reading fluency has been modeled as the product of discrete skills such as single word decoding. More recent conceptualizations emphasize that fluent reading is the product of competency in, and the coordination of...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.21384
更新日期:2012-11-01 00:00:00
abstract::The present study investigates human visual processing of simple two-colour patterns using a delayed match to sample paradigm with positron emission tomography (PET). This study is unique in that we specifically designed the visual stimuli to be the same for both pattern and colour recognition with all patterns being ...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:
更新日期:2001-08-01 00:00:00
abstract::Although imbalanced functional integration has been increasingly reported in major depressive disorder (MDD), there still lacks a general framework to characterize common characteristic and origin shared by the integrative disturbances. Here we examined spatial selectivity, temporal uniqueness, metabolic basis, and th...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.23976
更新日期:2018-05-01 00:00:00