Abstract:
:Dentin, the mineralized tissue forming the bulk of the tooth, lies between the enamel and the pulp chamber. It is a rich source of inspiration for designing novel synthetic materials due to its unique microstructure. Most of the previous studies investigating the fracture toughness of dentin have used linear-elastic fracture mechanics (LEFM) that ignores plastic deformation and could underestimate the toughness of dentin. With the presence of collagen (approximately 30% by volume) aiding the toughening mechanisms in dentin, we hypothesize that there is a significant difference between the fracture toughness estimated using LEFM (Kc) and elastic-plastic fracture mechanics (EPFM) (KJc). Single-edge notched beam specimens with in-plane (n=10) and anti-plane (n=10) parallel fractures were prepared following ASTM standard E1820 and tested in three-point flexure. KJc of the in-plane parallel and anti-plane parallel specimens were found to be 3.1 and 3.4 MPa m 1/2 and Kc were 2.4 and 2.5 MPa m 1/2, respectively. The fracture toughness estimated based on KJc is significantly greater than that estimated based on Kc (32.5% on average; p<0.001). In addition, KJc of anti-plane parallel specimens is significantly greater than that of in-plane parallel specimens. We suggest that, in order to critically evaluate the fracture toughness of human dentin, EPFM should be employed.
journal_name
J Biomechjournal_title
Journal of biomechanicsauthors
Yan J,Taskonak B,Platt JA,Mecholsky JJ Jrdoi
10.1016/j.jbiomech.2008.01.015subject
Has Abstractpub_date
2008-01-01 00:00:00pages
1253-9issue
6eissn
0021-9290issn
1873-2380pii
S0021-9290(08)00029-8journal_volume
41pub_type
杂志文章abstract::Muscle activity has previously been suggested to minimize soft-tissue resonance which occurs at heel-strike during walking and running. If this concept were true then the greatest vibration damping would occur when the input force was closest to the resonant frequency of the soft-tissues at heel-strike. However, this ...
journal_title:Journal of biomechanics
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/s0021-9290(03)00216-1
更新日期:2003-12-01 00:00:00
abstract::We propose a numerical model of hemodynamics arising from malaria infection. This model is based on a particle method, where all the components of blood are represented by the finite number of particles. A two-dimensional spring network of membrane particles is employed for expressing the deformation of malaria infect...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/j.jbiomech.2010.01.011
更新日期:2010-05-07 00:00:00
abstract::Patient-specific simulations of bone remodelling could enable predicting how bone micro-structural integrity would be affected by bone diseases, drugs or other factors, and, ultimately could help clinicians to improve their prognoses. To simulate load-adaptive remodelling, however, knowledge about the physiological ex...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/j.jbiomech.2012.12.012
更新日期:2013-03-15 00:00:00
abstract::Mechanical adaptions of cells, including stiffness variation, cytoskeleton remodeling, motion coordination, and shape changing, are essential for tissue morphogenesis, wound healing, and malignant progression. In this paper, we take confluent monolayers of Madin-Darby canine kidney (MDCK) and mouse myoblast (C2C12) ce...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/j.jbiomech.2020.109763
更新日期:2020-05-07 00:00:00
abstract::The mechanical properties of vertebrate erythrocytes depend on their cytoskeletal protein networks. Membrane skeleton proteins spectrin and protein 4.1 (4.1R) cross-link with actin to maintain membrane stability under mechanical stress. Phosphorylation of 4.1R alters the affinity of 4.1R for spectrin-actin binding and...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/j.jbiomech.2014.07.022
更新日期:2014-10-17 00:00:00
abstract::The finite element method described in this study provides an easy method to simulate the kinetics of multibody mechanisms. It is used in order to develop a musculoskeletal model of the shoulder mechanism. Each relevant morphological structure has been represented by an appropriate element. For the shoulder mechanism ...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/0021-9290(94)90065-5
更新日期:1994-05-01 00:00:00
abstract::Measures of local dynamic stability, such as the local divergence exponent (lambda*(s)) quantify how quickly small perturbations deviate from an attractor that defines the motion. When the governing equations of motion are unknown, an attractor can be reconstructed by defining an appropriate state space. However, stat...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/j.jbiomech.2009.03.015
更新日期:2009-06-19 00:00:00
abstract::The objective of this research was to use a pedal force decomposition approach to quantify the amount of negative muscular crank torque generated by a group of competitive cyclists across a range of pedaling rates. We hypothesized that negative muscular crank torque increases at high pedaling rates as a result of the ...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/s0021-9290(99)00100-1
更新日期:1999-10-01 00:00:00
abstract::The amount of microdamage in bone tissue impairs mechanical performance and may act as a stimulus for bone remodeling. Here we determine how loading mode (tension vs. compression) and microstructure (trabecular microarchitecture, local trabecular thickness, and presence of resorption cavities) influence the number and...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/j.jbiomech.2014.10.011
更新日期:2014-11-28 00:00:00
abstract::Local dynamic stability has been assessed by the short-term local divergence exponent (λS), which quantifies the average rate of logarithmic divergence of infinitesimally close trajectories in state space. Both increased and decreased local dynamic stability at faster walking speeds have been reported. This might pert...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/j.jbiomech.2014.09.020
更新日期:2014-11-28 00:00:00
abstract::Starting from the laws of thermodynamics of reversible processes, a temperature-dependent constitutive equation is derived for the elastic force-length relation of soft biological tissues. These tissues are composed of a network of fibres (mainly collagen). The equation is based on a model which uses a simplified two-...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/0021-9290(89)90222-4
更新日期:1989-01-01 00:00:00
abstract::This study investigated the contribution of small leucine rich proteoglycans (SLRPs) to the fracture toughness of the dentin extracellular matrix (ECM) by enzymatically-assisted selective removal of glycosaminoglycan chains (GAGs) and proteoglycans (PGs) core protein. We adapted the Mode III trouser tear test to evalu...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/j.jbiomech.2020.109633
更新日期:2020-03-05 00:00:00
abstract::A pair of finite element models has been employed to study the interaction of blood flow with the operation of the aortic valve. A three-dimensional model of the left ventricle with applied wall displacements has been used to generate data for the spatially and time-varying blood velocity profile across the aortic ape...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/j.jbiomech.2004.10.038
更新日期:2006-01-01 00:00:00
abstract::The measurement of relative motion between two moving bones is commonly accomplished for in vitro studies by attaching to each bone a series of either passive or active markers in a fixed orientation to create a rigid body (RB). This work determined the accuracy of motion between two RBs using an Optotrak optical moti...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/j.jbiomech.2006.01.017
更新日期:2007-01-01 00:00:00
abstract::The thoracolumbar fascia (TLF) provides a means of attachment to the lumbar spine for several muscles including the transverse abdominis, and parts of the latissimus dorsi and internal oblique muscles. Previous biomechanical models of the lumbar spine either tend to omit the TLF on the assumption that its contribution...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/j.jbiomech.2010.06.022
更新日期:2010-10-19 00:00:00
abstract::Sphenodon, a lizard-like reptile, is the only living representative of a group that was once widespread at the time of the dinosaurs. Unique jaw mechanics incorporate crushing and shearing motions to breakdown food, but during this process excessive loading could cause damage to the jaw joints and teeth. In mammals li...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/j.jbiomech.2010.08.001
更新日期:2010-12-01 00:00:00
abstract::The purpose of this paper is to present a simple clotting model, based on residence time and shear stress distribution, that can simulate the deposition over time of enzyme-activated milk in an in vitro system. Results for the model are compared with experiments exhibiting clot deposition in the region of a sharp-edge...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/j.jbiomech.2007.01.026
更新日期:2007-01-01 00:00:00
abstract::The aim of this work is to contribute to elucidating the mechanism underlying gas mixing in the human pulmonary airways. For this purpose, a particular attempt is made to analyse the fluid mechanical aspects of gaseous dispersion using bolus response methods. The experiments were performed on five normal subjects by i...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/0021-9290(85)90295-7
更新日期:1985-01-01 00:00:00
abstract::Physical activity in children is important as it leads to healthy growth due to physiological benefits. However, a physiological benefit can be partially negated by excessive or unphysiological loads within the joints. To gain an initial understanding into this, the present study sought to compare joint loading betwee...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/j.jbiomech.2019.01.051
更新日期:2019-04-18 00:00:00
abstract::Numerical differentiation of noisy measurement data represents a problem frequently encountered in the field of gait analysis. There are two major determinants of the quality in calculated derivatives, namely the quality of the measurement data and the quality of the used differentiation technique. The quality of the ...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/0021-9290(82)90041-0
更新日期:1982-01-01 00:00:00
abstract::Inertial measurement units (IMUs) offer great opportunities to analyze segmental and joints kinematics. When combined with another motion capture system (MCS), for example, to validate new IMU-based applications or to develop mixed systems, it is necessary to align the local frame of the IMU sensors to the local frame...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/j.jbiomech.2012.06.009
更新日期:2012-08-31 00:00:00
abstract::The role played by macrophage migration inhibitory factor (MIF) in the process of wound healing is controversial. Besides, there have been no reports that investigated the expression or the role of MIF in the repair process after ligament injury. In this study, we hypothesized that the deficiency in MIF gene might del...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/j.jbiomech.2010.09.018
更新日期:2011-02-03 00:00:00
abstract::Valgus moments on the knee joint during single-leg landing have been suggested as a risk factor for anterior cruciate ligament (ACL) injury. The purpose of this study was to test the influence of isolated valgus moment on ACL strain during single-leg landing. Physiologic levels of valgus moments from an in vivo study ...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/j.jbiomech.2008.10.031
更新日期:2009-02-09 00:00:00
abstract::Interstitial fluid flow has been shown to affect the organization and behavior of cells in 3D environments in vivo and in vitro, yet the forces driving such responses are not clear. Due to the complex architecture of the extracellular matrix (ECM) and the difficulty of measuring fluid flow near cells embedded in it, t...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/j.jbiomech.2006.06.023
更新日期:2007-01-01 00:00:00
abstract::The paper focuses on research that enables the relationship between food and selected mechanical parameters do be determined. The main aim of the study was to designate, depending on the food: (1) the work of a single muscle (i.e. masseter, medial pterygoid, temporalis), and (2) the energy balance of mandibular elevat...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/j.jbiomech.2020.109800
更新日期:2020-06-09 00:00:00
abstract::The purpose of this study was to find the optimal values of design parameters for a bicycle-rider system (crank length, pelvic inclination, seat height, and rate of crank rotation) which maximize the power output from muscles of the human lower limb during bicycling. The human lower limb was modelled as a planar syste...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/0021-9290(90)90322-t
更新日期:1990-01-01 00:00:00
abstract::The primary aim of this work is to investigate the potential of nonlinear ultrasound for microdamage detection in human bone. Microdamage evaluation in human bone is of great importance, because it is considered a significant parameter for characterizing fracture risk. Experiments employing nonlinear acoustic vibro-mo...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/j.jbiomech.2008.12.018
更新日期:2009-03-26 00:00:00
abstract::Differences in motion patterns subserving the same movement goal can be identified qualitatively. These alternatives, which may characterize 'movement techniques' (e.g., the stoop and the squat lifting technique), may be associated with significantly different biomechanical constraints and physiological responses. Des...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/j.jbiomech.2004.04.014
更新日期:2005-03-01 00:00:00
abstract::The use of a finite element based computational method, RFEM3D, is described for the study of strain-induced bone remodeling. The purpose of the research is to find the potential influence on the predictions of surface bone remodeling when various models for the maturation of newly deposited bone are used. A parameter...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/0021-9290(90)90015-u
更新日期:1990-01-01 00:00:00
abstract::A squeeze-film lubrication model of the human ankle joint in standing that takes into account the fluid transport across the articular surface is presented. Articular cartilage is a biphasic mixture of the ideal interstitial fluid and an elastic permeable isotropic homogeneous intrinsically incompressible matrix. The ...
journal_title:Journal of biomechanics
pub_type: 杂志文章
doi:10.1016/s0021-9290(00)00109-3
更新日期:2000-11-01 00:00:00