Type IV secretion system in Helicobacter pylori: a new insight into pathogenicity.

abstract：BACKGROUND:Hypoxia-inducible factor 1 (HIF-1), a transcription factor, is overexpressed in common human cancers and their metastases. This study aimed at determining the expression levels of HIF-1alpha and vascular endothelial growth factor (VEGF) in SW480 cells and in colorectal adenocarcinoma tissue and ascertaining ...

journal_title：Chinese medical journal

authors： Jiang CQ,Fan LF,Liu ZS,Qian Q,Xia D,Diao LM,He YM,Ai ZL

更新日期：2004-10-01 00:00:00

abstract：:Ninety-five patients with perforation, hemorrhage or stenosis due to duodenal ulcer were treated by extended parietal cell vagotomy. Postoperative follow-up ranged from 3.5 to 10 years (mean 6 years) in 88 patients (92%) with acute perforation (60), hemorrhage (8) and stenosis (20). There was no operative mortality. U...

journal_title：Chinese medical journal

authors： Li SY,An P,Liang ZJ,Yuan SJ,Yu J

更新日期：1992-04-01 00:00:00

abstract：BACKGROUND:Severe acute respiratory syndrome (SARS) is a disease with a mortality of 9.56%. Although SARS is etiologically linked to a new coronavirus (SARS-CoV) and functional cell receptor has been identified, the pathogenesis of the virus infection is largely unclear. METHODS:The clinical specimens were processed a...

journal_title：Chinese medical journal

authors： He WP,Shu CL,Li BA,Zhao J,Cheng Y

更新日期：2008-04-05 00:00:00

abstract：BACKGROUND:Interferon (IFN) can inhibit human immunodeficiency virus type 1 (HIV-1) replication in vitro and in clinic. However, IFN therapy for HIV infection was limited by its moderate antiviral efficacy and its frequent adverse effects. In the present study we evaluated the anti-HIV efficacy of a novel synthesized s...

journal_title：Chinese medical journal

authors： Zhang W,Tong X,Nakasone T,Yue XT,Yamamoto N,Liu XY,Yang RG

更新日期：2011-02-01 00:00:00

abstract：OBJECTIVE:To investigate the role of bax in a vincristine (VCR)-induced multidrug-resistant (MDR) human gastric cancer cell line, SGC7901/VCR, in which the Bax protein expression level was significantly lower compared with that in parent cells. METHODS:A bax eukaryotic expression vector was constructed and transfected...

journal_title：Chinese medical journal

authors： Zhao Y,Xiao B,Chen B,Qiao T,Fan D

更新日期：2000-11-01 00:00:00

abstract：BACKGROUND:Legionella is an important community-acquired pneumonia pathogen. Although the elderly are especially susceptible to Legionella, few studies have looked at comparative radiographic features of Legionella pneumonia in this population. The aim of this study was to explore the chest radiographic characteristics...

journal_title：Chinese medical journal

authors： Zhang Z,Liu X,Chen L,Qiu J

更新日期：2014-01-01 00:00:00

abstract：PURPOSE:To review the characteristics and evolution of the fungal spectrum, and the risk factors causing fungal infection, and to make progress in diagnosing fungal infection after organ transplantation. DATA SOURCES:An English-language literature search (MEDLINE 1990 - 2000) and bibliographic review of textbooks and ...

journal_title：Chinese medical journal

authors： Hong W,Wen H,Liao W

更新日期：2003-09-01 00:00:00

abstract：: ...

journal_title：Chinese medical journal

authors： Du Y,Zhao YX,Liu W,Zhang JW,Yan ZX,Zhou YJ

更新日期：2018-11-20 00:00:00

abstract：BACKGROUND:The development of the targeted signal transduction inhibitor STI571 has prompted us to treat chronic myeloid leukemia in different ways. Since STI571 may reverse multidrug-resistance of K562/MDR cells in vitro, we studied the effect of STI571 on multidrug-resistant K562 cells in vivo. METHODS:Multidrug-res...

journal_title：Chinese medical journal

authors： Gao L,Chen L,Fei XH,Qiu HY,Zhou H,Wang JM

更新日期：2006-06-05 00:00:00

abstract：BACKGROUND:Abdominal pain is a common symptom among patients with acute appendicitis, yet these patients have long been denied relief from suffering because of widespread misconceptions associated with the use of opioids. We determined whether morphine hydrochloride masked the physical signs in adults with acute append...

journal_title：Chinese medical journal

authors： Yuan Y,Chen JY,Guo H,Zhang Y,Liang DM,Zhou D,Zhao H,Lin F

更新日期：2010-01-20 00:00:00

abstract：OBJECTIVE:To investigate whether PreS1 antigen and/or anti-PreS1 antibody in serum might have some significance different from routine hepatitis B virus (HBV) markers in hepatitis B virus infection. METHODS:Forty-six acute hepatitis B patients and 377 chronic persistent hepatitis patients were examined to assess the c...

journal_title：Chinese medical journal

authors： Mi Z,Feng F,Zhang X,Lian Z,Wang H,Tong Y

更新日期：1999-04-01 00:00:00

abstract：BACKGROUND:Novel influenza A viruses of avian-origin may be the precursors of pandemic strains. This descriptive study aims to introduce a novel avian-origin influenza A (H10N8) virus which can infect humans and cause severe diseases. METHODS:Collecting clinical data of three cases of human infection with a novel reas...

journal_title：Chinese medical journal

authors： Zhang W,Wan J,Qian K,Liu X,Xiao Z,Sun J,Zeng Z,Wang Q,Zhang J,Jiang G,Nie C,Jiang R,Ding C,Li R,Horby P,Gao Z

更新日期：2014-01-01 00:00:00

abstract：OBJECTIVE:To investigate the effects of red orpiment on cell morphology, expression of promyelocytic leukemia (PML) mRNA and its protein localization in NB4 and HL-60 cell lines. METHODS:Cell morphology was assayed by Wright's staining and fluorescence staining, while PML mRNA expression was determined by RT-PCR. PML ...

journal_title：Chinese medical journal

authors： Zhong L,Chen F,Han J,Shao N,Ouyang R

更新日期：2003-01-01 00:00:00

abstract：OBJECTIVES:To investigate the effect of Burn Healing Liquid (BHL) on the proliferation of keratinocytes and fibroblasts and to explore the potential effect of BHL on fibroblast contraction. METHODS:Human keratinocytes and dermal fibroblasts were cultured in media containing serial dilutions of BHL followed by cell pro...

journal_title：Chinese medical journal

authors： Su Y,Chen B,Thang PT,Hughes MA,Xu X,Cherry GW

更新日期：1999-08-01 00:00:00

abstract：Background:Recent advances in extracorporeal membrane oxygenation (ECMO) have led to increasing interest in its use during cardiopulmonary resuscitation (CPR). However, decisions regarding extracorporeal CPR (ECPR) in children are difficult as a result of limited studies, especially in Asia Pacific. The objective of th...

journal_title：Chinese medical journal

authors： Chen GL,Qiao YR,Ma JH,Wang JX,Hei FL,Yu J

更新日期：2018-06-20 00:00:00

abstract：BACKGROUND:Smoking and body mass index (BMI) are the key risk factors for chronic obstructive pulmonary disease (COPD). Adiponectin with both anti-inflammatory and pro-inflammatory properties is a vital modulator of inflammatory processes, which is expressed in epithelial cells in the airway in COPD-emphysema. The aim ...

journal_title：Chinese medical journal

authors： Wang RY,Liu H,Ma LJ,Xu JY

更新日期：2016-01-20 00:00:00

abstract：BACKGROUND:Although some studies have reported that aquaporin-4 (AQP4) plays a role in the post-ischemic edema formation and diffusion-weighted imaging (DWI), little is known about the AQP4 expression in stage of the reperfusion following acute cerebral ischemia, as well as the correlation between histopathology and DW...

journal_title：Chinese medical journal

authors： Lu H,Hu H,He ZP

更新日期：2011-10-01 00:00:00

abstract：BACKGROUND:Cardiovascular diseases, especially coronary artery disease (CAD), are major causes of death in industrialized countries. Elevated concentrations of plasma homocysteine (Hcy) have been associated with an increased risk of CAD. Increased plasma levels of chemokine, characterized by their ability to induce mig...

journal_title：Chinese medical journal

authors： Wang G,Mao JM,Wang X,Zhang FC

更新日期：2004-11-01 00:00:00

abstract：BACKGROUND:Vascular endothelial growth factor (VEGF) is well known as a hypoxia-induced protein. That it markedly increased expression of VEGF and improvement of rat motor function after spinal cord injury suggested that VEGF could play a neuroprotective role in ischaemic tolerance. This study investigated whether vasc...

journal_title：Chinese medical journal

authors： Ding XM,Mao BY,Jiang S,Li SF,Deng YL

更新日期：2005-10-05 00:00:00

abstract：BACKGROUND:Diabetes mellitus plays an important role in cancer prevalence and outcomes. The aim of this study was to evaluate the influence of DM on stages and outcomes among patients with colorectal cancer. METHODS:The study enrolled 945 patients who were diagnosed as having colorectal carcinoma from August 1994 to D...

journal_title：Chinese medical journal

authors： Chen CQ,Fang LK,Cai SR,Ma JP,Yang GX,Yang W,Zhan WH,He YL

更新日期：2010-11-01 00:00:00

abstract：BACKGROUND:Airway mucus hypersecretion is an important pathophysiological feature of chronic obstructive pulmonary disease, which is closely associated with cigarette smoking. However, the signal transduction pathway from the cell surface to the nucleus through which cigarette smoke causes upregulation of mucin gene ex...

journal_title：Chinese medical journal

authors： Xiao J,Wang K,Feng YL,Chen XR,Xu D,Zhang MK

更新日期：2011-10-01 00:00:00

abstract：:Intraoperative coronary venography was performed in 24 patients before and after portal-azygos disconnection for portal hypertension. Before the procedure the portal vein was found to be communicated with cardial and esophageal veins by two pathways, i,e., from the esophageal and gastric branches of the coronary vein ...

journal_title：Chinese medical journal

authors： Zou ZS,Li JS,Li N,Liu FK

更新日期：1990-12-01 00:00:00

abstract：BACKGROUND:Balanced adjustment of the portal vein shunt volume during a transjugular intrahepatic portosystemic shunt (TIPS) is critical for maintaining liver perfusion and decreasing the incidence of liver insufficiency. A stent-graft is proved to be superior to a bare metal stent (BMS) for the construction of a TIPS....

journal_title：Chinese medical journal

authors： Wang CM,Li X,Fu J,Luan JY,Li TR,Zhao J,Dong GX

更新日期：2016-06-05 00:00:00

abstract：BACKGROUND:Pelizaeus-Merzbacher disease (PMD) is a rare X-linked recessive disorder with symptoms including nystagmus, impaired motor development, ataxia, and progressive spasticity. The proteolipid protein 1 (PLP1) gene is the only pathogenic gene of PMD. Duplication of the PLP1 gene is the most frequent gene defect, ...

journal_title：Chinese medical journal

authors： Wang JM,Wu Y,Wang HF,Deng YH,Yang YL,Qin J,Li XY,Wu XR,Jiang YW

更新日期：2008-09-05 00:00:00

abstract：OBJECTIVE:To summarize the recent findings on the epidemiology of medically important, opportunistic invasive fungal infections (IFIs) in China and discuss the relevant social, economical reasons and medical factors. DATA SOURCES:We performed a comprehensive search of both English and Chinese literatures of opportunis...

journal_title：Chinese medical journal

authors： Liao Y,Chen M,Hartmann T,Yang RY,Liao WQ

更新日期：2013-01-01 00:00:00

abstract：OBJECTIVE:According to the characteristics of digital medicine and the demands of digitalized management in hospitals, we established a storage system that is affordable, highly expandable, and reliable. METHODS:The multi personal computer storage system (MPCSS) was constructed using hardware and software. The image d...

journal_title：Chinese medical journal

authors： Guo Q,Hao F,Duan X,Xie X,Liao W

更新日期：2003-05-01 00:00:00

abstract：BACKGROUND:Restrictive cardiomyopathy (RCM) is the least common cardiomyopathy in which the walls are rigid and the heart is restricted from stretching and filling properly. Cardiac troponin I (cTnI) mutation-caused myofibril Ca2+ hypersensitivity has been shown to be associated with impaired diastolic function. This s...

journal_title：Chinese medical journal

authors： Ding WH,Han L,Xiao YY,Mo Y,Yang J,Wang XF,Jin M

更新日期：2017-12-05 00:00:00

abstract：OBJECTIVE:To evaluate the use of oxygen in neonates in the past, present and future. DATA SOURCES:The data are mainly from Pubmed with relevant published articles from the 1940s to the present with some information gathered from web searches. STUDY SELECTION:Studies evaluating the use of oxygen in premature and term ...

journal_title：Chinese medical journal

authors： Dennery PA

更新日期：2010-10-01 00:00:00

abstract：BACKGROUND:Previous studies have suggested that primary degeneration of hair cells causes secondary degeneration of spiral ganglion neurons (SGNs), but the effect of SGN degeneration on hair cells has not been studied. In the adult mouse inner ear ouabain can selectively and permanently induce the degeneration of type ...

journal_title：Chinese medical journal

authors： Yuan Y,Chi F

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Mutation or deletion in the phosphatase and tensin homologue deleted on chromosome ten (PTEN) gene has been identified as an important cause of endometrial carcinoma; stromal cell derived factor-1alpha (SDF-1alpha) exerts growth-promoting effects on endometrial cancer cells through activation of the PI-3 kin...

journal_title：Chinese medical journal

authors： Li XP,Zhao D,Gao M,Zhao C,Wang JL,Wei LH

更新日期：2006-03-05 00:00:00