Abstract：
:A correlative study between behavioral, neurochemical and hormonal measures was conducted on male black tufted-ear marmoset monkeys (Callithrix penicillata). Behavioral analysis was performed in order to examine the effects of confrontation with a natural predator (taxidermized oncilla cat, Felis tigrina). The subjects were subjected to four trials without predator, six confrontation trials with predator present, and four trials with the predator removed. Handedness was analyzed by the frequency with which they performed scratching, grooming and hanging behaviors with the left or right hands. The animals' brains were subjected to ex vivo neurochemical analysis of several structures from both hemispheres. The content of monoamines, acetycholine and metabolites were analyzed by HPLC-ED. Plasma levels of cortisol and adrenocorticotrophic hormone (ACTH) were analyzed by chemoluminescence immunoassay. Testosterone plasma concentration was determined by radioimmunoassay. Higher levels of dopamine and acetylcholine were detected in the right caudate/putamen, in comparison to the left. For the remaining areas, similar levels were observed in both hemispheres. A hand preference between and within the behaviors scored was not detected. However, correlative analyses revealed complex interactions between the behavioral and neurochemical measures, particularly in the left hemisphere. Lateralized correlations were found in relation to brain site, type of behavior, neurochemical parameter and treatment condition, thus providing evidence for functional brain asymmetries in this species. Interhemispheric comparisons of neurochemical/behavioral correlations appear to be a promising approach towards delineating hemispheric specialization of functions in this, and perhaps, other species.
journal_name
Brain Res Bulljournal_title
Brain research bulletinauthors
Silva MA,Topic B,Lamounier-Zepter V,Huston JP,Tomaz C,Barros Mdoi
10.1016/j.brainresbull.2007.07.012subject
Has Abstractpub_date
2007-11-01 00:00:00pages
416-28issue
6eissn
0361-9230issn
1873-2747pii
S0361-9230(07)00221-3journal_volume
74pub_type
杂志文章abstract：:Wnt/β-catenin signaling plays an essential role in blood-brain barrier (BBB) formation and maintenance under pathophysiological conditions. HLY78, a lycorine derivative, has been identified as a novel activator of Wnt/β-catenin signaling in vitro. However, the effects of HLY78 on the BBB function in subarachnoid hemor...
journal_title：Brain research bulletin
pub_type： 杂志文章
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更新日期：2020-09-01 00:00:00
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journal_title：Brain research bulletin
pub_type： 杂志文章
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journal_title：Brain research bulletin
pub_type： 杂志文章
doi：10.1016/0361-9230(86)90089-4
更新日期：1986-12-01 00:00:00
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journal_title：Brain research bulletin
pub_type： 杂志文章
doi：10.1016/s0361-9230(99)00194-x
更新日期：1999-11-01 00:00:00
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journal_title：Brain research bulletin
pub_type： 杂志文章
doi：10.1016/0361-9230(93)90164-7
更新日期：1993-01-01 00:00:00
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pub_type： 杂志文章
doi：10.1016/0361-9230(93)90034-9
更新日期：1993-01-01 00:00:00
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journal_title：Brain research bulletin
pub_type： 杂志文章
doi：10.1016/0361-9230(86)90219-4
更新日期：1986-10-01 00:00:00
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journal_title：Brain research bulletin
pub_type： 杂志文章
doi：10.1016/j.brainresbull.2015.07.001
更新日期：2015-08-01 00:00:00
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pub_type： 杂志文章
doi：10.1016/0361-9230(87)90139-0
更新日期：1987-05-01 00:00:00
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journal_title：Brain research bulletin
pub_type： 杂志文章
doi：10.1016/0361-9230(96)00118-9
更新日期：1996-01-01 00:00:00
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journal_title：Brain research bulletin
pub_type： 杂志文章
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更新日期：1989-07-01 00:00:00
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journal_title：Brain research bulletin
pub_type： 杂志文章,评审
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更新日期：1989-01-01 00:00:00
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journal_title：Brain research bulletin
pub_type： 杂志文章
doi：10.1016/0361-9230(77)90065-x
更新日期：1977-09-01 00:00:00
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journal_title：Brain research bulletin
pub_type： 杂志文章
doi：10.1016/0361-9230(84)90189-8
更新日期：1984-02-01 00:00:00
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journal_title：Brain research bulletin
pub_type： 杂志文章
doi：10.1016/j.brainresbull.2006.06.006
更新日期：2006-10-16 00:00:00
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journal_title：Brain research bulletin
pub_type： 杂志文章
doi：10.1016/0361-9230(92)90059-7
更新日期：1992-09-01 00:00:00
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journal_title：Brain research bulletin
pub_type： 杂志文章
doi：10.1016/0361-9230(80)90183-5
更新日期：1980-03-01 00:00:00
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journal_title：Brain research bulletin
pub_type： 杂志文章,评审
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更新日期：2000-01-15 00:00:00
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journal_title：Brain research bulletin
pub_type： 杂志文章
doi：10.1016/j.brainresbull.2006.10.014
更新日期：2007-04-30 00:00:00
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journal_title：Brain research bulletin
pub_type： 临床试验,杂志文章
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pub_type： 杂志文章
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更新日期：1984-10-01 00:00:00
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journal_title：Brain research bulletin
pub_type： 杂志文章
doi：10.1016/0361-9230(80)90207-5
更新日期：1980-11-01 00:00:00
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journal_title：Brain research bulletin
pub_type： 杂志文章
doi：10.1016/j.brainresbull.2017.11.018
更新日期：2018-03-01 00:00:00
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journal_title：Brain research bulletin
pub_type： 杂志文章
doi：10.1016/0361-9230(89)90075-0
更新日期：1989-02-01 00:00:00
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journal_title：Brain research bulletin
pub_type： 杂志文章
doi：10.1016/s0361-9230(00)00300-2
更新日期：2000-08-01 00:00:00
abstract：:The central GABAergic system is associated with normal blood pressure regulation, but the role of GABA receptors in genetic hypertension remains unclear. This study was conducted to investigate GABAA receptor binding in several brain regions of spontaneously hypertensive (SHR) rats during development of hypertension. ...
journal_title：Brain research bulletin
pub_type： 杂志文章
doi：10.1016/0361-9230(94)00164-v
更新日期：1995-01-01 00:00:00
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journal_title：Brain research bulletin
pub_type： 杂志文章,评审
doi：10.1016/0361-9230(85)90209-6
更新日期：1985-12-01 00:00:00
abstract：:Sequence variations in genes involved in inflammation system are known to contribute to the risk of cardiovascular diseases (CVD) including stroke. In this study, we performed a genetic association study on the single nucleotide polymorphisms (SNPs) present in the genes CD14 (-159 C/T), TNFalpha (-308 G/A), IL-1alpha ...
journal_title：Brain research bulletin
pub_type： 杂志文章
doi：10.1016/j.brainresbull.2007.08.007
更新日期：2008-01-31 00:00:00
abstract：:We previously reported that systemic treatment with a noncompetitive antagonist affecting the NMDA subtype of excitatory amino acid (EAA) receptor, MK-801, inhibits photic induction of Fos-like immunoreactivity (Fos-lir) in the hamster suprachiasmatic nucleus (SCN). Because MK-801 blocks the Ca2+ channel associated wi...
journal_title：Brain research bulletin
pub_type： 杂志文章
doi：10.1016/0361-9230(92)90269-4
更新日期：1992-05-01 00:00:00
abstract：:Ghrelin (Ghr) has two main forms in the blood: the acylated (A-Ghr) and non-acylated (NA-Ghr) Ghr. A-Ghr was discovered as a potent growth hormone (GH) secretion increasing substance acting on GH secretagouge receptor (GHS-R) type 1a. A-Ghr facilitates food intake after its i.p., i.c.v. or direct hypothalamic applicat...
journal_title：Brain research bulletin
pub_type： 杂志文章
doi：10.1016/j.brainresbull.2008.06.008
更新日期：2008-09-30 00:00:00
