The hippocampal indexing theory and episodic memory: updating the index.

abstract：:White matter hyperintensities (WMH) constitute the visible spectrum of cerebral small vessel disease (SVD) markers and are associated with cognitive decline, although they do not fully account for memory decline observed in individuals with SVD. We hypothesize that WMH might exert their effect on memory decline indire...

journal_title：Hippocampus

authors： van Leijsen EMC,Tay J,van Uden IWM,Kooijmans ECM,Bergkamp MI,van der Holst HM,Ghafoorian M,Platel B,Norris DG,Kessels RPC,Markus HS,Tuladhar AM,de Leeuw FE

更新日期：2019-06-01 00:00:00

abstract：:Granule cells with recurrent basal dendrites (RBDs) were previously reported in both control and epileptic rats. RBDs are dendrites that arise from the basal half of granule cell bodies and curve toward and extend into the molecular layer. They are increased in frequency in the pilocarpine model of epilepsy. The prese...

journal_title：Hippocampus

authors： Dashtipour K,Yan XX,Dinh TT,Okazaki MM,Nadler JV,Ribak CE

更新日期：2002-01-01 00:00:00

abstract：:Alzheimer's disease (AD) and ageing are associated with impaired learning and memory, and recent findings point toward modulating chromatin remodeling through histone acetylation as a promising therapeutic strategy. Here we report that systemic administration of the HDAC inhibitor 4-phenylbutyrate (PBA) reinstated fea...

journal_title：Hippocampus

authors： Ricobaraza A,Cuadrado-Tejedor M,Marco S,Pérez-Otaño I,García-Osta A

更新日期：2012-05-01 00:00:00

abstract：:Neuropsychologists have clearly implicated the hippocampus in the consolidation of memory, particularly episodic memory, the mental replay of past experiences. When recorded from behaving animals, by far the most obvious firing pattern of the primary neurons of the hippocampus is the place field: a cell tends to fire ...

journal_title：Hippocampus

authors： Kentros C

更新日期：2006-01-01 00:00:00

abstract：:There is extensive research regarding the neural mechanisms involved in satiety and meal termination; in contrast, there is very limited understanding of how meal onset is regulated. On the basis of several converging lines of evidence, we hypothesized that hippocampal neurons form a memory of a meal and inhibit meal ...

journal_title：Hippocampus

authors： Henderson YO,Smith GP,Parent MB

更新日期：2013-01-01 00:00:00

abstract：:Deficits in episodic memory are associated with deficits in the ability to imagine future experiences (i.e., mental time travel). We show that K.C., a person with episodic amnesia and an inability to imagine future experiences, nonetheless systematically discounts the value of future rewards, and his discounting is wi...

journal_title：Hippocampus

authors： Kwan D,Craver CF,Green L,Myerson J,Boyer P,Rosenbaum RS

更新日期：2012-06-01 00:00:00

abstract：:To study the possible involvement of the hippocampus in learned conditional responding, rats with aspiration lesions of the hippocampus and others that had the hippocampus removed with ibotenic acid were trained on concurrent Pavlovian conditional and nonconditional discriminations. In agreement with the results repor...

journal_title：Hippocampus

authors： Jarrard LE,Davidson TL

更新日期：1991-01-01 00:00:00

abstract：:Williams syndrome (WS), a genetic deletion syndrome, is characterized by severe visuospatial deficits affecting performance on both tabletop spatial tasks and on tasks which assess orientation and navigation. Nevertheless, previous studies of WS spatial capacities have ignored the fact that two different spatial memor...

journal_title：Hippocampus

authors： Bostelmann M,Fragnière E,Costanzo F,Di Vara S,Menghini D,Vicari S,Lavenex P,Lavenex PB

更新日期：2017-11-01 00:00:00

abstract：:Aging has been associated with a decline in relational memory, which is critically supported by the hippocampus. By adapting the transitivity paradigm (Bunsey and Eichenbaum (1996) Nature 379:255-257), which traditionally has been used in nonhuman animal research, this work examined the extent to which aging is accomp...

journal_title：Hippocampus

authors： Ryan JD,D'Angelo MC,Kamino D,Ostreicher M,Moses SN,Rosenbaum RS

更新日期：2016-02-01 00:00:00

abstract：:Trace eyeblink classical conditioning is a non-spatial learning paradigm that requires an intact hippocampus. This task is hippocampus-dependent because the auditory tone conditioned stimulus (CS) is temporally separated from the corneal airpuff unconditioned stimulus (US) by a 500-ms trace interval. Our laboratory ha...

journal_title：Hippocampus

authors： McEchron MD,Disterhoft JF

更新日期：1999-01-01 00:00:00

abstract：:Lynn Nadel has been a trailblazer in memory research for decades. In just one example, Nadel and Zola-Morgan [Infantile amnesia, In Infant memory, Springer, Boston, MA, 1984, pp. 145-172] were the first to present the provocative notion that the extended development of the hippocampus may underlie the period of infant...

journal_title：Hippocampus

authors： Edgin JO,Liu Y,Hughes K,Spanò G,Clark CAC

更新日期：2020-08-01 00:00:00

abstract：:Several recent studies have compared episodic and spatial memory in neuroimaging paradigms in order to understand better the contribution of the hippocampus to each of these tasks. In the present study, we build on previous findings showing common neural activation in default network areas during episodic and spatial ...

journal_title：Hippocampus

authors： Robin J,Hirshhorn M,Rosenbaum RS,Winocur G,Moscovitch M,Grady CL

更新日期：2015-01-01 00:00:00

abstract：:Our previous study showed that kainate (KA) receptor subunit GluR6 played an important role in ischemia-induced MLK3 and JNK activation and neuronal degeneration through the GluR6-PSD95-MLK3 signaling module. However, whether the KA receptors subunit GluR6 is involved in the activation of p38 MAP kinase during the tra...

journal_title：Hippocampus

authors： Chen J,Li C,Pei DS,Han D,Liu XM,Jiang HX,Wang XT,Guan QH,Wen XR,Hou XY,Zhang GY

更新日期：2009-01-01 00:00:00

abstract：:Gelsolin is an actin-binding protein that regulates actin filament-severing and capping activity in the various processes of cell motilities. Here, we report the expression of gelsolin mRNA and protein in the hippocampus following transections of the entorhinal afferents. Northern blot analysis showed that transcript ...

journal_title：Hippocampus

authors： Dong JH,Ying GX,Liu X,Wang WY,Wang Y,Ni ZM,Zhou CF

更新日期：2006-01-01 00:00:00

abstract：:Norepinephrine, is involved in the enhancement of learning and memory formation by regulating synaptic mechanisms through its ability to activate pre- and post-synaptic adrenergic receptors. Here we show that β-agonists of norepinephrine facilitate the induction of both associational LTP and sharp wave ripples (SPW-Rs...

journal_title：Hippocampus

authors： Ul Haq R,Anderson M,Liotta A,Shafiq M,Sherkheli MA,Heinemann U

更新日期：2016-12-01 00:00:00

abstract：:Key pathological features of Parkinson's Disease (PD) include the progressive degeneration of midbrain dopaminergic (DA) neurons and hindbrain noradrenergic (NA) neurons. The loss of DA neurons has been extensively studied and is the main cause of motor dysfunction. Importantly, however, there are a range of 'non-move...

journal_title：Hippocampus

authors： Ermine CM,Wright JL,Frausin S,Kauhausen JA,Parish CL,Stanic D,Thompson LH

更新日期：2018-05-01 00:00:00

abstract：:We present a neural network that characterizes a remarkably large number of classical conditioning paradigms and describes the effects of many neurophysiological manipulations. First, the network 1) describes behavior in real time 2) comprises simple and configural stimulus representations, and 3) includes attentional...

journal_title：Hippocampus

authors： Buhusi CV,Schmajuk NA

更新日期：1996-01-01 00:00:00

abstract：:Although the entorhinal cortex is a key structure connecting the hippocampal formation with the rest of the cerebral cortex, little is known about its early chemoanatomical development in primates. In the present study, a cytoarchitectonic analysis and immunocytochemical detection of somatostatin, neurotensin, parvalb...

journal_title：Hippocampus

authors： Berger B,Alvarez C,Goldman-Rakic PS

更新日期：1993-07-01 00:00:00

abstract：:The present study evaluated the effects of a single intrahippocampal administration of brain-derived neurotrophic factor (BDNF) on memory retention in a water maze. Adult rats were trained in a water maze (acquisition phase, day 1). Immediately after the last training trial subjects were injected in the right hippocam...

journal_title：Hippocampus

authors： Cirulli F,Berry A,Chiarotti F,Alleva E

更新日期：2004-01-01 00:00:00

abstract：:Replicas of an aspect of an experienced event can serve as effective reminders, yet little is known about the neural basis of such reminding effects. Here we examined the neural activity underlying the memory-enhancing effect of reminders 1 week after encoding of naturalistic film clip events. We used fMRI to determin...

journal_title：Hippocampus

authors： Sekeres MJ,Moscovitch M,Winocur G,Pishdadian S,Nichol D,Grady CL

更新日期：2021-01-01 00:00:00

abstract：:Adaptive memory requires the organism to form associations that bridge between events separated in time. Many studies show interactions between hippocampus (HPC) and prefrontal cortex (PFC) during formation of such associations. We analyze neural recording from monkey HPC and PFC during a memory task that requires the...

journal_title：Hippocampus

authors： Cruzado NA,Tiganj Z,Brincat SL,Miller EK,Howard MW

更新日期：2020-12-01 00:00:00

abstract：:Previous work has shown that the dorsal hippocampus has greater activity than ventral regions during place navigation. Exposure to a novel context has also been found to increase hippocampal activation, possibly due to increased spatial demands. However, activation patterns in dorsal and ventral regions have not been ...

journal_title：Hippocampus

authors： Lee JQ,Demchuk AM,Morgan E,McHugh R,McNaughton BL,Sutherland RJ,McDonald RJ

更新日期：2019-11-01 00:00:00

abstract：:In all species examined, the dentate gyrus develops over an extended period that begins during gestation and continues up to adulthood. The aim of this study was to investigate the pattern of postnatal cell production in the dentate gyrus of the guinea pig, a rodent whose brain development has features more closely re...

journal_title：Hippocampus

authors： Guidi S,Ciani E,Severi S,Contestabile A,Bartesaghi R

更新日期：2005-01-01 00:00:00

abstract：:In this study the subcortical afferents for the rat PER areas 35 and 36, POR, and the lateral and medial entorhinal areas (LEA and MEA) were characterized. We analyzed 33 retrograde tract-tracing experiments distributed across the five regions. For each experiment, we estimated the total numbers, percentages, and dens...

journal_title：Hippocampus

authors： Tomás Pereira I,Agster KL,Burwell RD

更新日期：2016-09-01 00:00:00

abstract：:Cocaine induces an increase in hippocampal and nucleus accumbens (Nac) serotonin (5-HT) concentration parallel to locomotor activation. Both effects can be modulated by systemic 5-HT(1A)-receptor agonism/antagonism. Given the contribution of the hippocampus to spontaneous behavioral activity, these observations sugges...

journal_title：Hippocampus

authors： Müller CP,Thönnessen H,Barros M,Tomaz C,Carey RJ,Huston JP

更新日期：2004-01-01 00:00:00

abstract：:We have previously shown that in urethane-anesthetized rats the frequency of rhythmical slow activity in the hippocampus ("theta") is controlled by the medial supramammillary nucleus (SuM). In particular, injections of procaine into SuM in urethane-anesthetized animals reduce the frequency of theta. However, it has be...

journal_title：Hippocampus

authors： McNaughton N,Logan B,Panickar KS,Kirk IJ,Pan WX,Brown NT,Heenan A

更新日期：1995-01-01 00:00:00

abstract：:One functional aspect of theta oscillations that recent studies have begun to explore in humans is their role for the recollection of personal events. A specific role of theta for recollection but not for stimulus-familiarity would support links between cortical theta oscillations and hippocampal functioning, given th...

journal_title：Hippocampus

authors： Guderian S,Düzel E

更新日期：2005-01-01 00:00:00

abstract：:Various forms of synaptic plasticity in the brain have been proposed to result from modifications in the properties of glutamate receptors by calcium-dependent mechanisms. In the present study, changes in glutamate receptors elicited by calcium treatment of previously frozen mouse brain sections were evaluated by qual...

journal_title：Hippocampus

authors： Lapierre L,Valastro B,Miceli D,Massicotte G

更新日期：2000-01-01 00:00:00

abstract：:The locomotor effects of intra-NAcc injection of dopamine receptor agonists following discrete lesion or inhibition of the DH or the VH have been poorly investigated using only the indirect dopamine receptor agonist amphetamine. In the present study, we investigated how lidocaine in the DH or the VH modulated hyperloc...

journal_title：Hippocampus

authors： Rouillon C,Abraini JH,David HN

更新日期：2007-01-01 00:00:00

abstract：:Exposing rats to an enriched environment over an extended period of time has been shown to enhance hippocampal long-term potentiation (LTP). Whether such prolonged exposure to environmental manipulation is necessary for LTP enhancement and whether the environmentally induced enhancement can persist long after the cess...

journal_title：Hippocampus

authors： Tang AC,Zou B

更新日期：2002-01-01 00:00:00