Lung function with carvedilol and bisoprolol in chronic heart failure: is beta selectivity relevant?

abstract：AIMS:The objective of this study was to establish the acute effects of hypoxia on clinical, spirometric, haemodynamic, and echocardiographic variables. Reducing inspired oxygen to 15%, as experienced during commercial air travel, decreases arterial oxygen saturation, increases respiratory rate and pulmonary artery pres...

journal_title：European journal of heart failure

authors： Hobkirk JP,Damy T,Walters M,Bennett A,Smith SJ,Ingle L,Clark AL,Cleland JG

更新日期：2013-05-01 00:00:00

abstract：OBJECTIVES:To compare the efficacy of the homeopathic Crataegus preparation Cralonin for non-inferiority to standard treatment for mild cardiac insufficiency. METHODS:Multicentre non-randomised cohort study in patients aged 50-75 years in New York Heart Association class II. Patients received Cralonin (n=110) or ACE i...

journal_title：European journal of heart failure

authors： Schröder D,Weiser M,Klein P

更新日期：2003-06-01 00:00:00

abstract：AIMS:Pulmonary hypertension (PH) due to systolic left ventricular dysfunction (PH-sLVD) frequently complicates heart failure (HF), and greatly worsens the prognosis of patients with sLVD, but as yet has no approved treatment. The LEPHT study aims to characterize the haemodynamic profile, safety, tolerability, and pharm...

journal_title：European journal of heart failure

authors： Ghio S,Bonderman D,Felix SB,Ghofrani HA,Michelakis ED,Mitrovic V,Oudiz RJ,Frey R,Roessig L,Semigran MJ

更新日期：2012-08-01 00:00:00

abstract：BACKGROUND:Mechanical stress plays a crucial role in tissue morphogenesis and remodeling. These processes depend in part on force transmission mediated through integrins and the cytoskeleton. METHODS:Ventricular myocytes isolated from neonatal Sprague-Dawley rats (NRVMs) were exposed to persistent centrifugal force st...

journal_title：European journal of heart failure

authors： Yutao X,Geru W,Xiaojun B,Tao G,Aiqun M

更新日期：2006-01-01 00:00:00

abstract：:Appropriate interpretation of changes in markers of kidney function is essential during the treatment of acute and chronic heart failure. Historically, kidney function was primarily assessed by serum creatinine and the calculation of estimated glomerular filtration rate. An increase in serum creatinine, also termed wo...

journal_title：European journal of heart failure

authors： Mullens W,Damman K,Testani JM,Martens P,Mueller C,Lassus J,Tang WHW,Skouri H,Verbrugge FH,Orso F,Hill L,Ural D,Lainscak M,Rossignol P,Metra M,Mebazaa A,Seferovic P,Ruschitzka F,Coats A

更新日期：2020-04-01 00:00:00

abstract：BACKGROUND:Although heart failure (HF) is a common cardiovascular disorder, to date little research has been conducted into possible associations between HF and structural abnormalities of the brain. AIMS:To determine the frequency and pattern of magnetic resonance imaging (MRI) abnormalities in outpatients with chron...

journal_title：European journal of heart failure

authors： Vogels RL,van der Flier WM,van Harten B,Gouw AA,Scheltens P,Schroeder-Tanka JM,Weinstein HC

更新日期：2007-10-01 00:00:00

abstract：AIMS:To investigate the prevalence of iron deficiency (ID) in heart failure (HF) patients with normal vs. abnormal red cell indices (RCI), the associations between iron parameters and RCI, and prognostic consequences of ID independently of RCI. METHODS AND RESULTS:We analysed clinical data of 1821 patients with HF [me...

journal_title：European journal of heart failure

authors： Tkaczyszyn M,Comín-Colet J,Voors AA,van Veldhuisen DJ,Enjuanes C,Moliner-Borja P,Rozentryt P,Poloński L,Banasiak W,Ponikowski P,van der Meer P,Jankowska EA

更新日期：2018-01-01 00:00:00

abstract：:Despite the availability of a number of different classes of therapeutic agents with proven efficacy in heart failure, the clinical course of heart failure patients is characterized by a reduction in life expectancy, a progressive decline in health-related quality of life and functional status, as well as a high risk ...

journal_title：European journal of heart failure

authors： Cowie MR,Filippatos GS,Alonso Garcia MLA,Anker SD,Baczynska A,Bloomfield DM,Borentain M,Bruins Slot K,Cronin M,Doevendans PA,El-Gazayerly A,Gimpelewicz C,Honarpour N,Janmohamed S,Janssen H,Kim AM,Lautsch D,Laws I,Lefk

更新日期：2017-06-01 00:00:00

abstract：BACKGROUND:Suppression of the renin-angiotensin-aldosterone system (RAAS) is therapeutically valuable in chronic heart failure (CHF). RAAS inhibition can be achieved in a number of ways though an orally active renin inhibitor (RI) has never been studied before. We describe the neurohumoral effects of an RI. METHODS AN...

journal_title：European journal of heart failure

authors： Seed A,Gardner R,McMurray J,Hillier C,Murdoch D,MacFadyen R,Bobillier A,Mann J,McDonagh T

更新日期：2007-11-01 00:00:00

abstract：:It is well known that atrial fibrillation can lead to heart failure, and is attributed to rapid ventricular rate (tachycardia-induced cardiomyopathy). Some recent studies suggest the possible existence of an intrinsic left-ventricular factor related to atrial fibrillation, irrespective of other elements. In order to d...

journal_title：European journal of heart failure

authors： Jourdain P,Bellorini M,Funck F,Fulla Y,Guillard N,Loiret J,Thebault B,Sadeg N,Desnos M

更新日期：2002-06-01 00:00:00

abstract：AIMS:Heart failure (HF) quality registries report quality of care but it is unknown whether they improve outcomes. The aims were to assess predictors of enrolment in a HF registry, test the hypothesis that enrolment in a HF registry is associated with reduced mortality, and assess potential explanatory factors for this...

journal_title：European journal of heart failure

authors： Lund LH,Carrero JJ,Farahmand B,Henriksson KM,Jonsson Å,Jernberg T,Dahlström U

更新日期：2017-09-01 00:00:00

abstract：AIMS:Ventricular septal rupture (VSR) became a rare mechanical complication of myocardial infarction in the era of percutaneous coronary interventions but is associated with extreme mortality in patients who present with cardiogenic shock (CS). Promising outcomes have been reported with the use of circulatory support a...

journal_title：European journal of heart failure

authors： Rob D,Špunda R,Lindner J,Rohn V,Kunstýř J,Balík M,Rulíšek J,Kopecký P,Lipš M,Šmíd O,Kovárník T,Mlejnský F,Linhart A,Bělohlávek J

更新日期：2017-05-01 00:00:00

abstract：AIMS:The aim of this study was to investigate the clinical picture and outcome of cardiogenic shock and to develop a risk prediction score for short-term mortality. METHODS AND RESULTS:The CardShock study was a multicentre, prospective, observational study conducted between 2010 and 2012. Patients with either acute co...

journal_title：European journal of heart failure

authors： Harjola VP,Lassus J,Sionis A,Køber L,Tarvasmäki T,Spinar J,Parissis J,Banaszewski M,Silva-Cardoso J,Carubelli V,Di Somma S,Tolppanen H,Zeymer U,Thiele H,Nieminen MS,Mebazaa A,CardShock Study Investigators.,GREAT network

更新日期：2015-05-01 00:00:00

abstract：AIMS:To determine the impact of internationally recognized criteria for the diagnosis of heart failure with preserved ejection fraction (HF-PEF) on the feasibility of recruitment into a HF-PEF trial. METHODS AND RESULTS:We reviewed the medical records of 5883 consecutive patients admitted with heart failure across eig...

journal_title：European journal of heart failure

authors： Patel HC,Hayward C,di Mario C,Cowie MR,Lyon AR,Rosen SD

更新日期：2014-07-01 00:00:00

abstract：AIMS:Cardiogenic shock is the leading cause of in-hospital mortality after acute myocardial infarction (MI). This study investigates the importance of age and preexisting diabetes mellitus on the incidence and prognosis of cardiogenic shock in a large group of consecutive patients with MI. METHODS AND RESULTS:Baseline...

journal_title：European journal of heart failure

authors： Lindholm MG,Boesgaard S,Torp-Pedersen C,Køber L,TRACE registry study group.

更新日期：2005-08-01 00:00:00

abstract：:The Elecsys NT-proBNP assay is based on two polyclonal antibodies directed at residues 1-21 and 39-50 of the NT-proBNP molecule. Analytical performance was assessed using NCCLS protocol EP-5A using three serum pools in a preliminary study then as part of a multicentre evaluation (16 instruments in 8 hospitals). Using ...

journal_title：European journal of heart failure

authors： Collinson PO,Barnes SC,Gaze DC,Galasko G,Lahiri A,Senior R

更新日期：2004-03-15 00:00:00

abstract：AIMS:Left ventricular contractile reserve is a prognostic indicator for adverse outcome in patients with severe chronic heart failure with reduced ejection fraction (HFrEF). We investigated the dobutamine-induced changes of LV multidimensional deformation and their predictive value for cardiac mortality of patients wit...

journal_title：European journal of heart failure

authors： Paraskevaidis IA,Ikonomidis I,Simitsis P,Parissis J,Stasinos V,Makavos G,Lekakis J

更新日期：2017-07-01 00:00:00

abstract：AIMS:Right ventricular (RV) dysfunction and pulmonary hypertension (PH) are increasingly recognized in heart failure with preserved ejection fraction (HFpEF). The prevalence and prognostic value of RV dysfunction in HFpEF have been widely but variably reported. We therefore conducted a systematic review and meta-analys...

journal_title：European journal of heart failure

authors： Gorter TM,Hoendermis ES,van Veldhuisen DJ,Voors AA,Lam CS,Geelhoed B,Willems TP,van Melle JP

更新日期：2016-12-01 00:00:00

abstract：AIMS:Recent studies have shown that microRNAs (miRNAs), besides being potent regulators of gene expression, can additionally serve as circulating biomarkers of disease. The aim of this study is to determine if plasma miRNAs can be used as indicators of disease progression or therapeutic efficacy in hypertension-induced...

journal_title：European journal of heart failure

authors： Dickinson BA,Semus HM,Montgomery RL,Stack C,Latimer PA,Lewton SM,Lynch JM,Hullinger TG,Seto AG,van Rooij E

更新日期：2013-06-01 00:00:00

abstract：AIMS:Current guidelines for the diagnosis of heart failure with normal or preserved ejection fraction (HFpEF) are based on measurements at rest. However, in HFpEF ventricular dysfunction is more apparent on exercise. We hypothesized that Mitral annular plane systolic excursion (MAPSE) which is easy to acquire on exerci...

journal_title：European journal of heart failure

authors： Wenzelburger FW,Tan YT,Choudhary FJ,Lee ES,Leyva F,Sanderson JE

更新日期：2011-09-01 00:00:00

abstract：BACKGROUND:Crataegus preparations have been used for centuries especially in Europe. To date, no proper data on their efficacy and safety as an add-on-treatment are available. Therefore a large morbidity/mortality trial was performed. AIM:To investigate the efficacy and safety of an add-on treatment with Crataegus ext...

journal_title：European journal of heart failure

authors： Holubarsch CJ,Colucci WS,Meinertz T,Gaus W,Tendera M,Survival and Prognosis: Investigation of Crataegus Extract WS 1442 in CHF (SPICE) trial study group.

更新日期：2008-12-01 00:00:00

abstract：:Many patients with Congestive Heart Failure (CHF) are anaemic. This anaemia is associated with more severe CHF and a higher incidence of mortality, hospitalisation and morbidity. The only way to prove that the anaemia is causing this worsening of CHF is to correct it. We review here some of the published papers about ...

journal_title：European journal of heart failure

authors： Silverberg DS,Wexler D,Iaina A,Schwartz D

更新日期：2008-09-01 00:00:00

abstract：AIMS:Growth differentiation factor-15 (GDF-15) is associated with adverse prognosis in cardiovascular (CV) and non-CV diseases. We evaluated the association of GDF-15 with CV and non-CV outcomes in the PARADIGM-HF trial. METHODS AND RESULTS:In 1935 patients with heart failure and reduced ejection fraction (HFrEF) in P...

journal_title：European journal of heart failure

authors： Bouabdallaoui N,Claggett B,Zile MR,McMurray JJV,O'Meara E,Packer M,Prescott MF,Swedberg K,Solomon SD,Rouleau JL,PARADIGM-HF Investigators and Committees.

更新日期：2018-12-01 00:00:00

abstract：INTRODUCTION:Atrial fibrillation (AF) is common in patients with heart failure (HF) due to left ventricular systolic dysfunction (LVSD), with conflicting prognostic data. The aim of our study was to assess the prevalence and incidence of AF in patients with HF and to determine the prognostic impact of baseline AF and t...

journal_title：European journal of heart failure

authors： Corell P,Gustafsson F,Schou M,Markenvard J,Nielsen T,Hildebrandt P

更新日期：2007-03-01 00:00:00

abstract：:Patients with obesity, a reduced exercise capacity, increased cardiac filling pressures and a measured left ventricular ejection fraction in the normal range do not have a homogeneous disorder, but instead, exhibit one of three phenotypes. First, many obese people exhibit sodium retention, plasma volume expansion and ...

journal_title：European journal of heart failure

authors： Packer M

更新日期：2019-02-01 00:00:00

abstract：AIMS:Undetected atrial fibrillation (AF) may be common in the heart failure with preserved ejection fraction (HFpEF) population, and failure to detect this may lead to the missing of opportunities to prevent associated subclinical cerebral infarctions (SCIs) and cognitive decline. METHODS AND RESULTS:We studied 1527 p...

journal_title：European journal of heart failure

authors： Cogswell RJ,Norby FL,Gottesman RF,Chen LY,Solomon S,Shah A,Alonso A

更新日期：2017-10-01 00:00:00

abstract：AIMS:Psychopathologies may occur in heart failure (HF) and can be associated with adverse outcomes. Amongst neuropeptide S receptor gene functional sequence variants, the T-allele [asparagine(107)isoleucine, NPSR1 rs324981] has been identified as a risk factor for increased anxiety/overinterpretation of bodily symptoms...

journal_title：European journal of heart failure

authors： Angermann CE,Kaspar M,Marx A,Kittel-Schneider S,Menhofer D,Störk S,Ertl G,Domschke K,Deckert J,Reif A

更新日期：2017-03-01 00:00:00

abstract：BACKGROUND:The association between serum digoxin concentration (SDC) and outcomes in women with heart failure (HF) has not been well studied. AIMS:To test the hypothesis that the effect of digoxin on outcomes in women with HF is bi-directional and dependent on SDC, as in men, and is modified by ejection fraction (EF)....

journal_title：European journal of heart failure

authors： Ahmed A,Aban IB,Weaver MT,Aronow WS,Fleg JL

更新日期：2006-06-01 00:00:00

abstract：AIMS:The Home or Hospital in Heart failure (HHH) study was a European Community-funded, multinational, randomized controlled clinical trial, conducted in the UK, Poland, and Italy, to assess the feasibility of a new system of home telemonitoring (HT). The HT system was used to monitor clinical and physiological paramet...

journal_title：European journal of heart failure

authors： Mortara A,Pinna GD,Johnson P,Maestri R,Capomolla S,La Rovere MT,Ponikowski P,Tavazzi L,Sleight P,HHH Investigators.

更新日期：2009-03-01 00:00:00

abstract：:The incidence and prevalence of cardiovascular disease increases progressively with advancing age. Cardiovascular disease is a major cause of morbidity and mortality in Western Countries. In the near future, as the population ages, it is expected that the population prevalence of cardiovascular disease will increase d...

journal_title：European journal of heart failure

authors： Wong LS,de Boer RA,Samani NJ,van Veldhuisen DJ,van der Harst P

更新日期：2008-11-01 00:00:00