Prevalence of spondyloarthropathies in an Italian population sample: a regional community-based study.

Abstract:

OBJECTIVE:To estimate the prevalence of spondyloarthropathies (SpA) in an adult population in Marche, a region located in central Italy. METHODS:A cross-sectional population-based study was conducted on a target adult population of 20 882. Questionnaires were sent to a random sample of 3664 individuals aged 18 years and over, selected from the lists of 16 general practices. Trained rheumatologists carried out structured visits in which respondent subjects were asked about symptoms of back pain, peripheral arthritis, joint swelling, psoriasis, and the occurrence of diarrhoea and dysuria. A family history of rheumatic disease, psoriasis, or uveitis was assessed. Cases were further classified as ankylosing spondylitis (AS), psoriatic arthritis (PsA), reactive arthritis (ReA), inflammatory bowel disease (IBD)-associated arthritis, and undifferentiated SpA by the European Spondyloarthropathy Study Group (ESSG) criteria. RESULTS:A total of 2155 subjects participated to the study (response rate 58.8%). Twenty-three cases of SpA (18 men, five women, mean age 48.3 +/- 12.1 years) were confirmed, with an overall prevalence of 1.06% [95% confidence interval (CI) 0.78-1.38]. The most common SpA was PsA, with a prevalence of 0.42% (95% CI 0.31-0.61), followed by AS with 0.37% (95% CI 0.23-0.49). Two cases with undifferentiated SpA, two with ReA, and two with IBD-associated arthritis were also observed (0.09%, 95% CI 0.04-0.16). CONCLUSIONS:This is the first population-based study that provides an estimate of the prevalence of SpA in Italy. PsA and AS were the most common SpA subsets. Further epidemiological studies are needed to obtain reliable prevalence rates and to better understand our findings.

journal_name

Scand J Rheumatol

authors

De Angelis R,Salaffi F,Grassi W

doi

10.1080/03009740600904243

subject

Has Abstract

pub_date

2007-01-01 00:00:00

pages

14-21

issue

1

eissn

0300-9742

issn

1502-7732

pii

777044584

journal_volume

36

pub_type

杂志文章
  • Achilles tendinitis in Vibrio vulnificus sepsis: a rare presentation.

    abstract::Vibrio vulnificus infection commonly presents as sepsis or wound infection. A case of alcoholic liver cirrhosis developed acute left heel pain and swelling 2 days after ingesting raw fish. Two sets of blood cultures indicated V. vulnificus. HLA-B27 was negative. Ultrasonography revealed left Achilles tendinitis. Fluid...

    journal_title:Scandinavian journal of rheumatology

    pub_type: 杂志文章

    doi:10.1080/03009740701721769

    authors: Yang CH,Shie SS,Yu KH,Jan Wu YJ

    更新日期:2008-05-01 00:00:00

  • Pain interference and associated factors in young adults with juvenile idiopathic arthritis.

    abstract::Objective: Pain is a common and distressing feature of juvenile idiopathic arthritis (JIA). Pain interference (PI) is underexplored in long-term conditions such as JIA. The aim of this study was to explore the factors associated with PI in young adults with JIA. Methods: All consecutive JIA patients aged 18-30 years i...

    journal_title:Scandinavian journal of rheumatology

    pub_type: 杂志文章,多中心研究

    doi:10.1080/03009742.2019.1596308

    authors: Rebane K,Orenius T,Ristolainen L,Relas H,Kautiainen H,Luosujärvi R,Säilä H,Aalto K

    更新日期:2019-09-01 00:00:00

  • Activated monocytes induce arthritis-associated changes in mitochondria of cultured synovial fibroblasts.

    abstract::We have recently shown that synovial fibroblasts cultured from patients with reactive or rheumatoid arthritis exhibit increased autofluorescence when compared with controls. Morphological studies suggested that this increase was related to the anomalous structure of mitochondria in cells cultured from rheumatoid or no...

    journal_title:Scandinavian journal of rheumatology

    pub_type: 杂志文章

    doi:10.3109/03009748809098773

    authors: Pulkki KJ,Eerola ET,Saario RM,Toivanen A,Vuorio EI

    更新日期:1988-01-01 00:00:00

  • More evidence of distinctive features of mixed connective tissue disease.

    abstract::A comparison of clinical, immunological and HLA-D region antigen features was made between 22 patients with mixed connective tissue disease (MCTD) and 118 patients with systemic lupus erythematosus (SLE), scleroderma or primary Sjögren's syndrome. The MCTD patients had hypergammaglobulinemia more often than did those ...

    journal_title:Scandinavian journal of rheumatology

    pub_type: 杂志文章

    doi:10.3109/03009749309095117

    authors: Hämeenkorpi R,Ruuska P,Forsberg S,Tiilikainen R,Mäkitalo R,Hakala M

    更新日期:1993-01-01 00:00:00

  • Immunohistochemical demonstration of insulin-like growth factor I in inflammatory lesions in Wegener's granulomatosis and idiopathic midline destructive disease.

    abstract::The immunoreactivity of the trophic peptide insulin-like growth factor I (IGF-I; somatomedin C) was mapped in nasal mucosa biopsies from three patients with Wegener's granulomatosis (WG) and one with idiopathic midline destructive disease (IMDD; idiopathic midline granuloma). Strongly increased IGF-I immuno-reactivity...

    journal_title:Scandinavian journal of rheumatology

    pub_type: 杂志文章

    doi:10.3109/03009748909095410

    authors: Hansson HA,Petruson B,Petruson K

    更新日期:1989-01-01 00:00:00

  • Orofacial pain and dysfunction in children with juvenile idiopathic arthritis: a case-control study.

    abstract:OBJECTIVES:Juvenile idiopathic arthritis (JIA) frequently causes temporomandibular joint (TMJ) inflammation. The aim of this study was to evaluate the presence of orofacial pain and temporomandibular dysfunction in patients with JIA and controls. METHODS. Forty-one patients with JIA and 41 age- and sex-matched healthy ...

    journal_title:Scandinavian journal of rheumatology

    pub_type: 杂志文章

    doi:10.3109/03009742.2012.675585

    authors: Leksell E,Ernberg M,Magnusson B,Hedenberg-Magnusson B

    更新日期:2012-10-01 00:00:00

  • Effects of a PEGylated soluble TNF receptor type 1 (PEG sTNF-RI) on cytokine expression in adjuvant arthritis.

    abstract:OBJECTIVE:To investigate the effects of TNF blocking therapy on synovial immune activity in rat adjuvant arthritis (AA) by measuring mRNA expression of key macrophage and T cell cytokines during PEG sTNF-RI treatment (10mg/kg) on days 8, 10 and 12. METHODS:Paw volume was assessed every 3-4 days. Ankles were removed fo...

    journal_title:Scandinavian journal of rheumatology

    pub_type: 杂志文章

    doi:10.1080/030097402320318378

    authors: Bush KA,Walker JS,Frazier J,Kirkham BW

    更新日期:2002-01-01 00:00:00

  • The prevalence of rheumatoid arthritis in different geographical areas in sweden.

    abstract::In the general population of 39,418 persons within areas in the counties of Norrbotten (BD), Jämtland (Z), Skaraborg (R), Kristianstad west coast (LV), and Kristianstad east coast (L) in Sweden all the inhabitants over the age of seven (in Norrbotten over the age of 14) were investigated for the total number of cases ...

    journal_title:Scandinavian journal of rheumatology

    pub_type: 杂志文章

    doi:10.3109/03009747009165382

    authors: Hellgren L

    更新日期:1987-01-01 00:00:00

  • Tumour necrosis factor (TNF)alpha -308 G/G promoter polymorphism and TNFalpha levels correlate with a better response to adalimumab in patients with rheumatoid arthritis.

    abstract:OBJECTIVE:To investigate the influence of -308 tumour necrosis factor-alpha (TNFalpha) promoter polymorphism and circulating TNFalpha levels in the clinical response to adalimumab treatment in patients with rheumatoid arthritis (RA). METHODS:Eighty-one patients with active RA were genotyped for the -308 TNFalpha polym...

    journal_title:Scandinavian journal of rheumatology

    pub_type: 杂志文章

    doi:10.1080/03009740600904284

    authors: Cuchacovich M,Soto L,Edwardes M,Gutierrez M,Llanos C,Pacheco D,Sabugo F,Alamo M,Fuentealba C,Villanueva L,Gatica H,Schiattino I,Salazaro L,Catalan D,Valenzuela O,Salazar-Onfray F,Aguillón JC

    更新日期:2006-11-01 00:00:00

  • Rasch analysis of the Norwegian version of the Arthritis Self-Efficacy Scale (ASES).

    abstract:OBJECTIVES:To apply the Rasch model to the Norwegian version of the Arthritis Self-Efficacy Scale (ASES). METHOD:The ASES was included in a self-administered questionnaire sent to 224 patients attending one of three rehabilitation centres for rheumatic diseases in Norway in 2009. The fit of the ASES to the Rasch model...

    journal_title:Scandinavian journal of rheumatology

    pub_type: 杂志文章

    doi:10.3109/03009742.2016.1155644

    authors: Garratt AM,Klokkerud M,Løchting I,Hagen KB

    更新日期:2017-01-01 00:00:00

  • Increased chromosome damage in systemic sclerosis skin fibroblasts.

    abstract:OBJECTIVE:To evaluate chromosome damage, by means of micronucleus frequency, in dermal fibroblasts from affected and non-affected skin from systemic sclerosis (SSc) patients and from controls. METHODS:Primary fibroblast cultures were obtained by biopsy from affected and non-affected skin from SSc patients. Control fib...

    journal_title:Scandinavian journal of rheumatology

    pub_type: 杂志文章

    doi:10.3109/03009741003685640

    authors: Martins EP,Fuzzi HT,Kayser C,Alarcon RT,Rocha MG,Chauffaille ML,Andrade LE

    更新日期:2010-01-01 00:00:00

  • T(H)1 cytokines are produced in labial salivary glands in Sjögren's syndrome, but also in healthy individuals.

    abstract::The aim of the present study was to assess the T cell cytokines IFN-gamma, IL-2, IL-4 and IL-5 in labial salivary glands (LSG) in Sjögren's syndrome (SS) and healthy controls using RT-PCR and immunohistochemistry. IFN-gamma is always or almost always produced in SS and in healthy controls. IL-2 was also found in some ...

    journal_title:Scandinavian journal of rheumatology

    pub_type: 杂志文章

    doi:10.1080/030097499442577

    authors: Konttinen YT,Kemppinen P,Koski H,Li TF,Jumppanen M,Hietanen J,Santavirta S,Salo T,Larsson A,Hakala M,Sorsa T

    更新日期:1999-01-01 00:00:00

  • Quality of life in chronic NSAID users: a comparison of the effect of omeprazole and misoprostol.

    abstract:OBJECTIVE:To compare the impact on quality of life (QoL) of omeprazole and misoprostol during healing, and omeprazole, misoprostol, and placebo during maintenance treatment in chronic NSAID users with NSAID-associated gastroduodenal lesions. METHODS:Validated baseline and follow-up QoL questionnaires were completed by...

    journal_title:Scandinavian journal of rheumatology

    pub_type: 临床试验,杂志文章

    doi:10.1080/030097401317148516

    authors: Yeomans N,Wilson I,Långström G,Hawkey C,Naesdal J,Walan A,Wiklund I

    更新日期:2001-01-01 00:00:00

  • Long-term outcome of rheumatoid arthritis has improved.

    abstract::X-rays of 20 finger joints, 10 foot joints and 2 wrists of 50 female patients with seropositive rheumatoid arthritis of 10-15 years' duration from 1962, 1972, 1982 and 1992 were evaluated blindly for erosions. A highly significant decline was observed in erosions in finger joints. Erosions had also declined in wrists ...

    journal_title:Scandinavian journal of rheumatology

    pub_type: 杂志文章

    doi:10.3109/03009749409102128

    authors: Heikkilä S,Isomäki H

    更新日期:1994-01-01 00:00:00

  • Pulmonary miliary tuberculosis in a patient with anti-TNF-alpha treatment.

    abstract::No difference in the number of serious adverse events was reported in previous clinical trials in rheumatoid arthritis (RA) and inflammatory bowel disease (IBD) patients treated with TNF-alpha blockade, but a patient died because of disseminated tuberculosis. A tuberculosis reactivation in a patient with IBD and anti-...

    journal_title:Scandinavian journal of rheumatology

    pub_type: 杂志文章

    doi:10.1080/030097402317255372

    authors: Mayordomo L,Marenco JL,Gomez-Mateos J,Rejon E

    更新日期:2002-01-01 00:00:00

  • Quality of life in rheumatoid arthritis.

    abstract::Assessment of health-related quality of life (HRQoL) is relevant for the patients and is important in both clinical research and daily clinical practice. Generic and disease-specific instruments for assessment of HRQoL are reviewed. Changes in HRQoL provide important information on randomized controlled clinical trial...

    journal_title:Scandinavian journal of rheumatology

    pub_type: 杂志文章,评审

    doi:10.1080/03009740500327727

    authors: Kvien TK,Uhlig T

    更新日期:2005-09-01 00:00:00

  • The effect of multimeric adiponectin isoforms and leptin on the function of rheumatoid fibroblast-like synoviocytes.

    abstract:OBJECTIVES:To evaluate the effects of physiologically relevant concentrations of multimeric adiponectin isoforms and leptin on the function of fibroblast-like synoviocytes (FLS) from patients with rheumatoid arthritis (RA). METHOD:FLS, isolated from the synovial tissue of 21 RA patients, were stimulated for 24 h with ...

    journal_title:Scandinavian journal of rheumatology

    pub_type: 杂志文章

    doi:10.3109/03009742.2015.1025833

    authors: Kontny E,Janicka I,Skalska U,Maśliński W

    更新日期:2015-01-01 00:00:00

  • Adherence to cardiovascular prevention strategies in patients with rheumatoid arthritis.

    abstract:OBJECTIVES:Patients with rheumatoid arthritis (RA) have a high risk of cardiovascular disease (CVD). Recent national and international guidelines suggest strict treatment of CVD risk factors in RA. The aim of this study was to evaluate the self-reported adherence to CV prevention strategies in patients with RA. METHOD...

    journal_title:Scandinavian journal of rheumatology

    pub_type: 杂志文章

    doi:10.3109/03009742.2015.1028997

    authors: van Breukelen-van der Stoep DF,Zijlmans J,van Zeben D,Klop B,van de Geijn GJ,van der Meulen N,Hazes M,Birnie E,Castro Cabezas M

    更新日期:2015-01-01 00:00:00

  • Differentiation between early rheumatoid arthritis patients and healthy persons by conventional and dynamic contrast-enhanced magnetic resonance imaging.

    abstract:OBJECTIVES:To identify the magnetic resonance imaging (MRI) parameter that best differentiates healthy persons and patients with early rheumatoid arthritis (RA), and to investigated responsiveness to treatment of various MRI parameters. METHOD:Conventional MRI and dynamic contrast-enhanced (DCE)-MRI of the hand were p...

    journal_title:Scandinavian journal of rheumatology

    pub_type: 杂志文章

    doi:10.3109/03009742.2013.824022

    authors: Axelsen MB,Ejbjerg BJ,Hetland ML,Skjødt H,Majgaard O,Lauridsen UB,Hørslev-Petersen K,Boesen M,Kubassova O,Bliddal H,Østergaard M

    更新日期:2014-01-01 00:00:00

  • Serum levels of soluble interleukin-2 receptor in patients with systemic lupus erythematosus and systemic idiopathic vasculitis.

    abstract::Soluble interleukin 2 receptor (sIL2R) may be used as an index of immune perturbation. We report on the correlation between the serum levels of sIL2R, as assessed with a sandwich-ELISA, and disease activity in 61 patients with Systemic Lupus Erythematosus (SLE) and in 15 with systemic idiopathic vasculitis (SIV). The ...

    journal_title:Scandinavian journal of rheumatology

    pub_type: 杂志文章

    doi:10.3109/03009749309095125

    authors: Danieli MG,Paoletti P,Recchioni A,Gabrielli A,Danieli G

    更新日期:1993-01-01 00:00:00

  • Effects of osmium tetroxide on the rabbit knee joint normal synovial membrane.

    abstract::The effect of osmium tetroxide, which is used in treatment of rheumatoid arthritis, was histologically and electronmicroscopically examined in the normal synovial membrane of the rabbit. The animals were albino rabbits, and they were 20 altogether. 0.3 ml. of 1% OsO(4) solution was injected, i.a., in the right knee. T...

    journal_title:Scandinavian journal of rheumatology

    pub_type: 杂志文章

    doi:10.3109/03009747009165362

    authors: Möttönen M,Pantio M,Nevalainen T

    更新日期:1987-01-01 00:00:00

  • Prevalence and predictors of vitamin D deficiency in non-supplemented women with systemic lupus erythematosus in the Mediterranean region: a cohort study.

    abstract:OBJECTIVES:Over the past few years researchers have suggested that vitamin D plays a diverse role in autoimmune diseases such as systemic lupus erythematosus (SLE). We sought to determine the prevalence and predictors of vitamin D deficiency in a cohort of non-supplemented female SLE patients from the Mediterranean reg...

    journal_title:Scandinavian journal of rheumatology

    pub_type: 杂志文章

    doi:10.3109/03009742.2012.697189

    authors: Muñoz-Ortego J,Torrente-Segarra V,Prieto-Alhambra D,Salman-Monte TC,Carbonell-Abello J

    更新日期:2012-01-01 00:00:00

  • Radiographic measurements of severe temporomandibular joint destruction at cervical radiography. Designed for evaluation in rheumatoid arthritis.

    abstract::Radiological examinations of the temporomandibular joints are not so often performed in patients with rheumatoid arthritis (RA). However, greater abnormalities of the mandibular head and neck may be evaluated at cervical radiography. With a new method, where the perpendicular distance from the palato-occipital line to...

    journal_title:Scandinavian journal of rheumatology

    pub_type: 杂志文章

    doi:10.3109/03009748709102507

    authors: Redlund-Johnell I

    更新日期:1987-01-01 00:00:00

  • No effect of low power laser in lateral epicondylitis.

    abstract::Thirty-six patients with lateral epicondylitis of the elbow (19 women, 17 men, median age 48 yrs) were treated either with active laser or placebo, 18 patients in each group. The active laser was a GA-AL-AS 30 mW/830 nm low power laser (LPL). The study design was double blind and randomized. The treatment session cons...

    journal_title:Scandinavian journal of rheumatology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.3109/03009749409103726

    authors: Krasheninnikoff M,Ellitsgaard N,Rogvi-Hansen B,Zeuthen A,Harder K,Larsen R,Gaardbo H

    更新日期:1994-01-01 00:00:00

  • The safety profile of low-dose cladribine in refractory rheumatoid arthritis. A pilot trial.

    abstract::Cladribine (2-chlorodeoxyadenosine, 2-CdA) is a newer purine analog with specific toxicity to lymphocytes. As lymphocytes play a major role in rheumatoid arthritis (RA), we assessed the safety profile of low-dose 2-CdA in patients who were refractory to more than three disease-modifying drugs. Five patients were given...

    journal_title:Scandinavian journal of rheumatology

    pub_type: 临床试验,杂志文章

    doi:10.3109/03009749709065702

    authors: Schirmer M,Mur E,Pfeiffer KP,Thaler J,Konwalinka G

    更新日期:1997-01-01 00:00:00

  • Cationic myeloma M-components frequently show cross-reacting anti-DNA, Anti-F(ab')2 and anti-nucleosome specificities.

    abstract::134 cationic human IgG myeloma proteins were studied for expression of anti-DNA Idiotypic markers. 64 were studied for 16/6, F4, 3I, and 8.12, and 70 for expression of F4 and 3I. 31.3% showed at least one anti-DNA Id marker and many cationic myelomas were also positive for anti-DNA ELISA reactivity as well as anti-F(a...

    journal_title:Scandinavian journal of rheumatology

    pub_type: 杂志文章

    doi:10.3109/03009749709115823

    authors: Williams RC Jr,Malone CC,Silvestris F

    更新日期:1997-01-01 00:00:00

  • Zinc: its relationship to osteoporosis in rheumatoid arthritis.

    abstract::Preliminary studies indicate that plasma zinc concentrations, as estimated by atomic absorption spectrophotometry, are reduced in rheumatoid arthritis. A relationship has also been established between metacarpal index of osteoporosis and plasma zinc concentrations in rheumatoid subjects. ...

    journal_title:Scandinavian journal of rheumatology

    pub_type: 杂志文章

    doi:10.3109/03009747509165264

    authors: Kennedy AC,Fell GS,Rooney PJ,Stevens WH,Dick WC,Buchanan WW

    更新日期:1975-01-01 00:00:00

  • Magnetic resonance imaging of the femoral head to detect avascular necrosis in active rheumatoid arthritis treated with methylprednisolone pulse therapy.

    abstract::Efficacious management of patients with avascular necrosis of bone (AVN) necessitates the identification of patients with a high risk of collapse of the femoral head. In this prospective study we imaged both hips of 10 patients with active rheumatoid arthritis, who were treated with methylprednisolone pulse therapy. M...

    journal_title:Scandinavian journal of rheumatology

    pub_type: 杂志文章

    doi:10.3109/03009749609069211

    authors: van Vugt RM,Sijbrandij ES,Bijlsma JW

    更新日期:1996-01-01 00:00:00

  • Xerostomia due to Sjögren's syndrome. Diagnostic criteria, treatment and outlines for a continuous dental care programme and an open trial with Sulfarlem.

    abstract::The initial evaluation of 25 patients suspected of suffering from Sjögren's syndrome (SS) disclosed that sialopenia and glandular atrophy without focal sialo-adenitis was the second most common cause, after SS itself, of patient complaints. This emphasizes the importance of conclusive diagnostic criteria to prevent ov...

    journal_title:Scandinavian journal of rheumatology

    pub_type: 临床试验,杂志文章

    doi:10.3109/03009748809098766

    authors: Malmström MJ,Segerberg-Konttinen M,Tuominen TS,Hietanen JH,Wolf JE,Sane JI,Konttinen YT

    更新日期:1988-01-01 00:00:00

  • In situ characterization of the cellular infiltrate in labial and palatine glands in Sjögren's syndrome.

    abstract::The inflammatory cells in the minor salivary glands in situ in 11 patients with Sjögren's syndrome were characterized by using intracellular markers for T lymphocytes, plasma cells, mononuclear phagocytes and granulocytes. The methods used to demonstrate the markers were optimized histochemical and immunoperoxidase te...

    journal_title:Scandinavian journal of rheumatology

    pub_type: 杂志文章

    doi:10.3109/03009748109095324

    authors: Konttinen YT

    更新日期:1981-01-01 00:00:00