T(H)1 cytokines are produced in labial salivary glands in Sjögren's syndrome, but also in healthy individuals.

abstract：OBJECTIVES:Progressive destruction of synovial joint cartilage and bone occurs in pathological conditions such as rheumatoid arthritis (RA) because of the overproduction of pro-inflammatory cytokines and activation of nuclear factor kappa B (NF-κB). Through the screening of NF-κB inhibitors by a luciferase reporter gen...

journal_title：Scandinavian journal of rheumatology

authors： Liu Q,Zhao J,Tan R,Zhou H,Lin Z,Zheng M,Romas E,Xu J,Sims NA

更新日期：2015-05-01 00:00:00

abstract：OBJECTIVES:Thyroid dysfunction in the setting of systemic sclerosis (SSc) has been described previously. We aimed to determine the prevalence of anti-thyroid antibodies (ATA) in a large SSc cohort and to ascertain whether they are associated with distinct clinical phenotypes. METHODS:A total of 138 patients with SSc [...

journal_title：Scandinavian journal of rheumatology

authors： Danielides S,Mavragani CP,Katsakoulas I,Zintzaras E,Drosos AA,Vlachoyiannopoulos PG,Moutsopoulos HM

更新日期：2011-01-01 00:00:00

abstract：:Ultrasound detects effusion and synovial proliferation caused by synovitis. The study was undertaken to evaluate the signs of synovitis in patients with primary Sjögren's Syndrome (SS). Joint effusion was detected and synovial thickness was measured in the suprapatellar synovial bursa. Results have been compared with ...

journal_title：Scandinavian journal of rheumatology

authors： Iagnocco A,Coari G,Palombi G,Valesini G

更新日期：2002-01-01 00:00:00

abstract：BACKGROUND:The study was done to determine whether the new SCORE (Simple Calculated Osteoporosis Risk Estimation) index might reduce the utilization of bone mineral density (BMD) measurement. METHODS:989 consecutive patients who were referred by a range of physicians for BMD assessments at one of two clinics had a SCO...

journal_title：Scandinavian journal of rheumatology

authors： Russell AS,Morrison RT

更新日期：2001-01-01 00:00:00

abstract：:Objectives: IgG4-related disease (IgG4-RD) may present as 'idiopathic' retroperitoneal fibrosis (IRPF). We aimed to determine the occurrence of IgG4-retroperitoneal fibrosis (IgG4-RPF) in a nationwide study on patients with newly diagnosed IRPF, and to compare histopathological, imaging, and clinical features in the I...

journal_title：Scandinavian journal of rheumatology

authors： Lomborg N,Jakobsen M,Bode CS,Junker P

更新日期：2019-07-01 00:00:00

abstract：:An account is given of a viscometer which can be used for measuring the viscosity of synovial fluid when only small quantities are avaliable (0.15 ml) and taking into account the non-Newtonian character of the fluid. A technical description of the apparatus is given. A series of experiments are reported in which bovin...

journal_title：Scandinavian journal of rheumatology

authors： Reimann I,Stougaard J,Northeved A

更新日期：1975-01-01 00:00:00

abstract：OBJECTIVES:This study examined differences in reactions to disability between early and established rheumatoid arthritis (RA) patients, and whether these reactions were related to age, physical functioning, acceptance of illness, or self-efficacy. METHODS:Thirty-four patients with early RA (< 2 years since diagnosis) ...

journal_title：Scandinavian journal of rheumatology

authors： Treharne GJ,Lyons AC,Booth DA,Mason SR,Kitas GD

更新日期：2004-01-01 00:00:00

abstract：OBJECTIVE:To investigate the molecular and biochemical profile of skeletal muscle mitochondria of patients with isolated polymyalgia rheumatica (PMR). PATIENTS AND METHODS:We included patients with a recent diagnosis of PMR and as control healthy individuals submitted to orthopedic surgery. Skeletal muscle was obtaine...

journal_title：Scandinavian journal of rheumatology

authors： Miró O,Jarreta D,Casademont J,Barrientos A,Rodríguez B,Gómez M,Nunes V,Urbano-Márquez A,Cardellach F

更新日期：1999-01-01 00:00:00

abstract：OBJECTIVES:The aim of this study was to describe fear-avoidance beliefs about physical activity and explore how these beliefs correlate with sociodemographic, disease-specific, and psychosocial factors in adults with rheumatoid arthritis (RA). METHOD:This cross-sectional study is part of the Physical Activity in Rheum...

journal_title：Scandinavian journal of rheumatology

authors： Lööf H,Demmelmaier I,Henriksson EW,Lindblad S,Nordgren B,Opava CH,Johansson UB

更新日期：2015-01-01 00:00:00

abstract：:Glucocorticoids (GCs) have powerful and potent anti-inflammatory and immunomodulatory effects in rheumatoid arthritis (RA) and many other diseases. These effects are mediated by up to four different mechanisms of action: cytosolic glucocorticoid receptor (cGCR)-mediated classical genomic and rapid non-genomic effects,...

journal_title：Scandinavian journal of rheumatology

authors： Buttgereit F,Saag KG,Cutolo M,da Silva JA,Bijlsma JW

更新日期：2005-01-01 00:00:00

abstract：:We report the case of a 41-year-old man diagnosed with Still's disease. Multiple disease-modifying anti-rheumatic drug (DMARD) therapies failed to induce disease remission or to prevent progressive joint destruction. The man presented with active arthritis and classical Still's rash accompanied by fever. Anti-tumour n...

journal_title：Scandinavian journal of rheumatology

authors： Thonhofer R,Soleiman A,Kriessmayr M,Thonhofer U,Wipfler E,Gaugg M,Eder S,Erlacher L

更新日期：2006-11-01 00:00:00

abstract：:A total of 62 rheumatoid knee joints were treated with intra-articular 90Y. Results were assessed by clinical, roentgenologic and thermographic examination after a six-month follow-up. The majority of the joints had moderate roentgenologic manifestations of RA before treatment. The roentgenologic stage of the disease ...

journal_title：Scandinavian journal of rheumatology

authors： Jalava S,Räsänen O

更新日期：1975-01-01 00:00:00

abstract：OBJECTIVE:Chronic renal disease other than scleroderma renal crisis (SRC) is not well documented in systemic sclerosis (SSc). We examined the occurrence of decreased glomerular filtration rate (GFR) in a large consecutive SSc cohort and analysed whether it was related to SSc or could be related to other causes. METHOD...

journal_title：Scandinavian journal of rheumatology

authors： Scheja A,Bartosik I,Wuttge DM,Hesselstrand R

更新日期：2009-01-01 00:00:00

abstract：:The effects of piroxicam and D-penicillamine on T lymphocytes, NK cell activity and rheumatoid factor production as well as clinical parameters were studied in patients with rheumatoid arthritis. The level of total rheumatoid factor fell during treatment with D-penicillamine (p less than 0.02) and there was a positive...

journal_title：Scandinavian journal of rheumatology

authors： Thoen J,Helgetveit K,Førre O,Haile Y,Kåss E

更新日期：1988-01-01 00:00:00

abstract：:Nine patients suffering from chronic rheumatoid arthritis were each given single doses of 1 g acetylsalicylic acid, in the form of each of the preparations studied: an enteric-coated tablet, a microcrystalline tablet, and a capsule containing enterosoluble granules. Absorption from each preparation was good in all pat...

journal_title：Scandinavian journal of rheumatology

authors： Martio J,Kahela P

更新日期：1983-01-01 00:00:00

abstract：OBJECTIVE:Interleukin-1 (IL-1) has been implicated in the pathogenesis of several rheumatic inflammatory diseases, including adult-onset Still's disease (AOSD) and systemic-onset juvenile idiopathic arthritis (SoJIA). Several clinical trials also suggest that anakinra, a human recombinant interleukin-1 receptor antagon...

journal_title：Scandinavian journal of rheumatology

authors： Youm JY,Woo JH,Kim TH,Bae SC,Yoo DH

更新日期：2007-09-01 00:00:00

abstract：:Presenting symptoms in polymyalgia rheumatica (PMR) may be atypical. We report herein two old females who developed a bilateral carpal tunnel syndrome several months before the typical symptoms of PMR appeared. In both patients the diagnosis of PMR was overlooked and a surgical release of the median nerve was performe...

journal_title：Scandinavian journal of rheumatology

authors： Herrera B,Sanmartí R,Ponce A,Lopez-Soto A,Muñoz-Gómez J

更新日期：1997-01-01 00:00:00

abstract：:We report the case of a 50-year-old man who presented with systemic vasculitis associated with Fasciola hepatica infection. The patient presented with severe skin, kidney, spleen, ophthalmic, and neurological compromise. An immunological examination for primary vasculitis was negative and other infections were discoun...

journal_title：Scandinavian journal of rheumatology

authors： Llanos C,Soto L,Sabugo F,Gallegos I,Valenzuela O,Verdaguer J,Cuchacovich M

更新日期：2006-03-01 00:00:00

abstract：OBJECTIVES:Reactive arthritis (ReA) is a sterile joint inflammation triggered by a remote infection and associated with human leucocyte antigen (HLA)-B27. Its pathogenesis is unknown, but abnormal response to microbial structures or endogenous inflammatory mediators may be involved. We studied responses in leucocyte si...

journal_title：Scandinavian journal of rheumatology

authors： Alanärä T,Aittomäki S,Kuuliala K,Kuuliala A,Siitonen S,Leirisalo-Repo M,Repo H

更新日期：2012-08-01 00:00:00

abstract：OBJECTIVES:Ischaemic digital ulcers (DUs) are a common complication of systemic sclerosis (SSc). This study aimed to characterize patients with SSc and ongoing DUs treated with the endothelin receptor antagonist bosentan in clinical practice in France. METHOD:An observational, retrospective, longitudinal study was con...

journal_title：Scandinavian journal of rheumatology

authors： Agard C,Carpentier PH,Mouthon L,Clerson P,Gressin V,Bérezné A,Diot E,Jego P,Lok C,Sparsa A,Chatelus E,Van Kien AK,Quéré I,Sibilia J,Hachulla E

更新日期：2014-01-01 00:00:00

abstract：OBJECTIVES:Calcium hydroxyapatite (HA) is reported to be the major constituent of soft tissue calcinosis in patients with scleroderma (systemic sclerosis, SSc). Mechanical stress and local tissue hypoxia are thought to be important in the pathogenesis of SSc calcinosis. We sought to analyse spontaneously draining mater...

journal_title：Scandinavian journal of rheumatology

authors： Hsu VM,Emge T,Schlesinger N

更新日期：2017-03-01 00:00:00

abstract：:Objective: Low molecular mass hyaluronan causes inflammatory processes and can act as a pro-inflammatory cytokine in skin and other sites of activity in psoriatic arthritis (PsA). This study investigated whether the molecular mass distribution of hyaluronan (HA) in skin and the quantity of circulating HA are related t...

journal_title：Scandinavian journal of rheumatology

authors： Hellman U,Engström-Laurent A,Larsson A,Lindqvist U

更新日期：2019-07-01 00:00:00

abstract：:Vibrio vulnificus infection commonly presents as sepsis or wound infection. A case of alcoholic liver cirrhosis developed acute left heel pain and swelling 2 days after ingesting raw fish. Two sets of blood cultures indicated V. vulnificus. HLA-B27 was negative. Ultrasonography revealed left Achilles tendinitis. Fluid...

journal_title：Scandinavian journal of rheumatology

authors： Yang CH,Shie SS,Yu KH,Jan Wu YJ

更新日期：2008-05-01 00:00:00

abstract：:Whole blood cell culture has great advantage over isolated peripheral blood mononuclear cell culture, because it needs only small amounts of blood and is fast to perform. The current report focuses on the measurement of IL-6 and TNF alpha produced by peripheral blood monocytes of patients with systemic lupus erythemat...

journal_title：Scandinavian journal of rheumatology

authors： Swaak AJ,van den Brink HG,Aarden LA

更新日期：1996-01-01 00:00:00

abstract：OBJECTIVES:The use of statins in the prevention and treatment of cardiovascular diseases is well established. Their use as anti-inflammatory and immunomodulatory agents in the treatment of rheumatoid arthritis (RA) has also been investigated, with several clinical and experimental studies indicating an anti-inflammator...

journal_title：Scandinavian journal of rheumatology

authors： Gottschalk O,Dao Trong ML,Metz P,Wallmichrath J,Piltz S,Jauch KW,Jansson V,Schmitt-Sody M

更新日期：2014-01-01 00:00:00

abstract：OBJECTIVES:Foot orthoses are commonly prescribed as an intervention for people with rheumatoid arthritis (RA). Data relating to the cost-effectiveness of foot orthoses in people with RA are limited. The aim was to evaluate the clinical and cost-effectiveness of two types of foot orthoses in people with established RA. ...

journal_title：Scandinavian journal of rheumatology

authors： Rome K,Clark H,Gray J,McMeekin P,Plant M,Dixon J

更新日期：2017-05-01 00:00:00

abstract：OBJECTIVES:To (i) examine the association between fatigue, psychosocial work characteristics (job control, support, participation in decision making, psychological job demands), and physical work requirements on the one hand and work ability of employees with rheumatoid arthritis (RA) on the other, and (ii) determine t...

journal_title：Scandinavian journal of rheumatology

authors： de Croon EM,Sluiter JK,Nijssen TF,Kammeijer M,Dijkmans BA,Lankhorst GJ,Frings-Dresen MH

更新日期：2005-07-01 00:00:00

abstract：OBJECTIVES:To study the link between metabolic syndrome (MetS), endothelial injury, and atherosclerosis in patients with systemic lupus erythematosus (SLE). METHODS:Consecutive SLE patients without a history of arterial thrombosis were screened for atherosclerosis at the carotid and coronary arteries by B-mode ultraso...

journal_title：Scandinavian journal of rheumatology

authors： Mok CC,Poon WL,Lai JP,Wong CK,Chiu SM,Wong CK,Lun SW,Ko GT,Lam CW,Lam CS

更新日期：2010-01-01 00:00:00

abstract：:Cladribine (2-chlorodeoxyadenosine, 2-CdA) is a newer purine analog with specific toxicity to lymphocytes. As lymphocytes play a major role in rheumatoid arthritis (RA), we assessed the safety profile of low-dose 2-CdA in patients who were refractory to more than three disease-modifying drugs. Five patients were given...

journal_title：Scandinavian journal of rheumatology

authors： Schirmer M,Mur E,Pfeiffer KP,Thaler J,Konwalinka G

更新日期：1997-01-01 00:00:00

abstract：:Primary cultures of neonatal dermal fibroblasts from two strains of mice (A/J and C57BL6/J) were utilized as an in vitro system to investigate the effects of glucocorticoids on cell growth and collagen synthesis. Protein and DNA synthesis were lower in untreated (control) A/J fibroblasts than in C57BL6/J fibroblasts. ...

journal_title：Scandinavian journal of rheumatology

authors： Verbruggen LA,Orloff S,Rao VH,Salomon DS

更新日期：1983-01-01 00:00:00