Cytokine production (IL-6 and TNF alpha) in whole blood cell cultures of patients with systemic lupus erythematosus.

abstract：OBJECTIVE:To evaluate the efficacy of the essential omega-6 fatty acid Gammalinolenic acid (GLA) on fatigue associated with primary Sjögren's syndrome. METHODS:Ninety patients with primary Sjögren's syndrome (with or without signs of autoimmunity) entered a 6-month double blind placebo-controlled randomised trial with...

journal_title：Scandinavian journal of rheumatology

authors： Theander E,Horrobin DF,Jacobsson LT,Manthorpe R

更新日期：2002-01-01 00:00:00

abstract：OBJECTIVES:Measurement of serum biomarkers at disease onset may improve prediction of disease course in patients with early rheumatoid arthritis (RA). We evaluated the multi-biomarker disease activity (MBDA) score and early changes in MBDA score for prediction of 28-joint Disease Activity Score based on C-reactive prot...

journal_title：Scandinavian journal of rheumatology

authors： Brahe CH,Østergaard M,Johansen JS,Defranoux N,Wang X,Bolce R,Sasso EH,Ørnbjerg LM,Hørslev-Petersen K,Stengaard-Pedersen K,Junker P,Ellingsen T,Ahlquist P,Lindegaard H,Linauskas A,Schlemmer A,Dam MY,Hansen I,Lottenburg

更新日期：2019-01-01 00:00:00

abstract：:ANA testing by immunofluorescence technique (F-ANA) is nowadays still performed in much the same way as 45 years ago when the test was introduced. Due to its low specificity the F-ANA test has a poor predictive value for systemic autoimmune diseases and in addition has proven difficult to standardise. In the meantime,...

journal_title：Scandinavian journal of rheumatology

authors： Nossent H,Rekvig OP

更新日期：2001-01-01 00:00:00

abstract：OBJECTIVES:The aim of this study was to test whether orosomucoid like 3 (ORMDL3) and 17q21 variants are associated with susceptibility to ankylosing spondylitis (AS) in a Chinese population. METHOD:A total of 753 unrelated AS patients and 1120 ethnically matched healthy controls were recruited. Seven single nucleotide...

journal_title：Scandinavian journal of rheumatology

authors： Qiu R,Zhang H,Zhao H,Li J,Guo C,Gong Y,Liu Q

更新日期：2013-01-01 00:00:00

abstract：:Primary Sjögren's syndrome (pSS) is a connective tissue disease with symptoms and serological findings often overlapping with systemic lupus erythematosus (SLE) (1). Thromboembolic events are common in SLE but not in pSS (2)(3). However, case reports have described pSS patients who developed fulminant multiorgan disea...

journal_title：Scandinavian journal of rheumatology

authors： Haga HJ,Jacobsen EM,Peen E

更新日期：2008-03-01 00:00:00

abstract：:Medium from cultured bovine synovial membrane when applied to articular cartilage from the same animal enhanced proteoglycan breakdown, as measured by the release of [35S]sulphate from prelabelled cartilage, principally by activating chondrocytes to secrete or activate their own enzymes. This effect persisted whether ...

journal_title：Scandinavian journal of rheumatology

authors： Jones IL,Klämfeldt A,McGuire MB

更新日期：1982-01-01 00:00:00

abstract：:In a series of 100 adult patients with definite rheumatoid arthritis of at most 3 years' duration and with no previous penicillamine, gold or systemic corticosteroid treatment, 50 patients were treated with D-penicillamine and 50 with gold for one yar. The dose of penicillamine was 600 mg daily. Sodium aurothiomalate ...

journal_title：Scandinavian journal of rheumatology

authors： Mäkisara P,Nissilä M,Kajander A,Martio J,von Essen R,Anttila P,Mäkisara GL

更新日期：1978-01-01 00:00:00

abstract：OBJECTIVE:To determine whether HLA-DR alleles are associated with the development and clinical features of systemic sclerosis (SSc) in Koreans. METHODS:Seventy-nine patients (74 women and five men; 45 diffuse types and 34 limited types; mean age at diagnosis 43.9 years) fulfilling the American College of Rheumatology ...

journal_title：Scandinavian journal of rheumatology

authors： Joung CI,Jun JB,Chung WT,Song GG,Choe JY,Chang HK,Yoo DH

更新日期：2006-01-01 00:00:00

abstract：:Efficacious management of patients with avascular necrosis of bone (AVN) necessitates the identification of patients with a high risk of collapse of the femoral head. In this prospective study we imaged both hips of 10 patients with active rheumatoid arthritis, who were treated with methylprednisolone pulse therapy. M...

journal_title：Scandinavian journal of rheumatology

authors： van Vugt RM,Sijbrandij ES,Bijlsma JW

更新日期：1996-01-01 00:00:00

abstract：OBJECTIVES:Foot orthoses are commonly prescribed as an intervention for people with rheumatoid arthritis (RA). Data relating to the cost-effectiveness of foot orthoses in people with RA are limited. The aim was to evaluate the clinical and cost-effectiveness of two types of foot orthoses in people with established RA. ...

journal_title：Scandinavian journal of rheumatology

authors： Rome K,Clark H,Gray J,McMeekin P,Plant M,Dixon J

更新日期：2017-05-01 00:00:00

abstract：OBJECTIVES:To determine which variables at baseline are predictive for the development of rheumatoid arthritis (RA) from palindromic rheumatism (PR) in a Japanese population. METHODS:Anti-cyclic citrullinated peptide (anti-CCP) antibodies, joint involvement pattern, genotypes of HLA-DRB1, peptidylarginine deiminase (P...

journal_title：Scandinavian journal of rheumatology

authors： Tamai M,Kawakami A,Iwamoto N,Arima K,Aoyagi K,Eguchi K

更新日期：2010-08-01 00:00:00

abstract：:We studied HLA antigens in 105 unrelated American Caucasian patients with rheumatoid arthritis (RA), 70 of them with familial disease. HLA-DR4 was observed in 71% of familial RA, 63% of non-familial RA, and 27% of normal controls, confirming the already well-established association between HLA-DR4 and both familial an...

journal_title：Scandinavian journal of rheumatology

authors： Khan MA,Wolfe F,Kleinheksel SM,Molta C

更新日期：1987-01-01 00:00:00

abstract：OBJECTIVES:To assess the prevalence of interstitial lung disease (ILD) in patients with different forms of connective tissue disease (CTD) using non-invasive procedures including high-resolution computed tomography (HRCT) and to evaluate the relationship between the imaging and functional status of the patients. METHO...

journal_title：Scandinavian journal of rheumatology

authors： Afeltra A,Zennaro D,Garzia P,Gigante A,Vadacca M,Ruggiero A,Dardes N,Navajas MF,Zobel BB,Amoroso A

更新日期：2006-09-01 00:00:00

abstract：:In the general population of 39,418 persons within areas in the counties of Norrbotten (BD), Jämtland (Z), Skaraborg (R), Kristianstad west coast (LV), and Kristianstad east coast (L) in Sweden all the inhabitants over the age of seven (in Norrbotten over the age of 14) were investigated for the total number of cases ...

journal_title：Scandinavian journal of rheumatology

authors： Hellgren L

更新日期：1987-01-01 00:00:00

abstract：:An investigation has been carried out on the presence of iron in striated muscle from normal individuals and from patients with rheumatoid disease. The methods used for the estimation of iron required a neutron activation analysis of total iron and extraction of hemoglobin in cyanide buffer. The results disclosed that...

journal_title：Scandinavian journal of rheumatology

authors： Goldie IF,Bjönness T,Tiselius P,Plantin LO,Sato T

更新日期：1976-01-01 00:00:00

abstract：:An enzyme-linked immunosorbent assay was used to detect antiglobulins (rheumatoid factors, RF) of various classes in 33 patients with recently diagnosed rheumatoid arthritis and to follow their progress with 3-monthly checks for 1 year. For RF, IgA-RF and IgM-RF showed greater sensitivity than the latex test, either o...

journal_title：Scandinavian journal of rheumatology

authors： March RE,Kirwan JR,Reeback JS,Holborow EJ

更新日期：1987-01-01 00:00:00

abstract：OBJECTIVE:To evaluate the association between trabecular bone score (TBS) and new bone formation in ankylosing spondylitis (AS) patients, and to investigate whether TBS is independently associated with new bone formation. METHOD:Sixty-eight patients with AS underwent spinal magnetic resonance imaging (MRI) and dual-en...

journal_title：Scandinavian journal of rheumatology

authors： Kang KY,Jung JY,Lee SK,Min HK,Hong YS,Park SH,Ju JH

更新日期：2020-07-01 00:00:00

abstract：:The aim of the present study was to relate postural control, as measured on a quantitative test battery as standing balance on an AMTI force platform, to results of muscle function of the lower extremities, aerobic capacity, disease characteristics, attitudes revealing anxiety, and demographic variables in patients wi...

journal_title：Scandinavian journal of rheumatology

authors： Ekdahl C

更新日期：1992-01-01 00:00:00

abstract：OBJECTIVES:To study the prevalence of comorbid conditions at diagnosis and during follow-up in a cohort of patients with early rheumatoid arthritis (RA) followed prospectively over 20 years, and to identify possible early predictive factors for future comorbidities. METHODS:A community-based cohort of 183 patients (me...

journal_title：Scandinavian journal of rheumatology

authors： Kapetanovic MC,Lindqvist E,Simonsson M,Geborek P,Saxne T,Eberhardt K

更新日期：2010-01-01 00:00:00

abstract：OBJECTIVE:To estimate the prevalence of spondyloarthropathies (SpA) in an adult population in Marche, a region located in central Italy. METHODS:A cross-sectional population-based study was conducted on a target adult population of 20 882. Questionnaires were sent to a random sample of 3664 individuals aged 18 years a...

journal_title：Scandinavian journal of rheumatology

authors： De Angelis R,Salaffi F,Grassi W

更新日期：2007-01-01 00:00:00

abstract：OBJECTIVES:Over the past few years researchers have suggested that vitamin D plays a diverse role in autoimmune diseases such as systemic lupus erythematosus (SLE). We sought to determine the prevalence and predictors of vitamin D deficiency in a cohort of non-supplemented female SLE patients from the Mediterranean reg...

journal_title：Scandinavian journal of rheumatology

authors： Muñoz-Ortego J,Torrente-Segarra V,Prieto-Alhambra D,Salman-Monte TC,Carbonell-Abello J

更新日期：2012-01-01 00:00:00

abstract：:The objective was to study the long-term effect (2 years) of different training programs in patients with rheumatoid arthritis. The method was a randomized trial with 75 patients participating. The measured variables included morning stiffness, a pain score, number of swollen joints, a health assessment score, a funct...

journal_title：Scandinavian journal of rheumatology

authors： Hansen TM,Hansen G,Langgaard AM,Rasmussen JO

更新日期：1993-01-01 00:00:00

abstract：:Cyclic adenosine-3', 5'-monophosphate (cAMP) may influence important mechanisms in the inflammatory process, and fasting has been claimed to be clinically beneficial in rheumatoid arthritis (RA). A study was therefore designed to measure the concentrations of plasma cAMP in RA patients not undergoing drug treatment du...

journal_title：Scandinavian journal of rheumatology

authors： Trang LE,Lövgren O,Bendz R,Mjös O

更新日期：1980-01-01 00:00:00

abstract：:A comparison of clinical, immunological and HLA-D region antigen features was made between 22 patients with mixed connective tissue disease (MCTD) and 118 patients with systemic lupus erythematosus (SLE), scleroderma or primary Sjögren's syndrome. The MCTD patients had hypergammaglobulinemia more often than did those ...

journal_title：Scandinavian journal of rheumatology

authors： Hämeenkorpi R,Ruuska P,Forsberg S,Tiilikainen R,Mäkitalo R,Hakala M

更新日期：1993-01-01 00:00:00

abstract：:The prevalence of rheumatoid arthritis in 1,287 persons living in densely populated areas and 1, 287 persons living in thinly populated areas, matched as to sex, age, occupation and geographical area, was compared. The patient material was obtained in an epidemiological survey of rheumatoid arthritis (ARA definition) ...

journal_title：Scandinavian journal of rheumatology

authors： Hellgren L

更新日期：1987-01-01 00:00:00

abstract：:The lupus anticoagulant (LAC) is associated with the occurrence of thromboembolic complications. Assuming that thrombosis may underlie manifestations of the central nervous system (CNS) in patients with systemic lupus erythematosus (SLE), we studied 20 patients with SLE and CNS manifestations for the presence of LAC. ...

journal_title：Scandinavian journal of rheumatology

authors： Derksen RH,Bouma BN,Kater L

更新日期：1986-01-01 00:00:00

abstract：OBJECTIVE:To investigate the clonal characteristics of B cells in the synovial membranes of rheumatoid arthritis (RA) patients. METHODS:The clonality of B cells at separate sites of the synovial membrane and other tissues from RA patients were investigated by a reverse transcriptase-polymerase chain reaction with a VH...

journal_title：Scandinavian journal of rheumatology

authors： Shiokawa S,Matsumato N,Nishimura J

更新日期：2003-01-01 00:00:00

abstract：:Linné and Boissier de la Croix de Sauvages, two botanists and physicians of the mideighteenth century, proposed systems for the classification of diseases. Their medical works have been examined for passages suggestive of rheumatoid arthritis (RA). References to gouty arthritis dominated in Linné's works. Sauvages des...

journal_title：Scandinavian journal of rheumatology

authors： Hansen SE

更新日期：1993-01-01 00:00:00

abstract：:In biopsies from normal-looking skin, immune complexes in the dermo-epidermal junction zone were found by a direct immunofluorescence technique in 14 of 17 patients with systemic lupus erythematosus, in 6 of 12 patients with rheumatoid arthritis, but in none of 10 patients with temporal arteritis and 25 normal control...

journal_title：Scandinavian journal of rheumatology

authors： Permin H,Juhl F,Wiik A,Balslov JT

更新日期：1977-01-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to analyse differences in clinical presentation in patients with early (< 3 years' duration) systemic sclerosis (SSc), comparing three age groups according to disease subsets. METHOD:Cross-sectional analysis of the prospective EULAR Scleroderma Trials and Research database (EUSTAR) ...

journal_title：Scandinavian journal of rheumatology

authors： Carreira PE,Carmona L,Joven BE,Loza E,Andréu JL,Riemekasten G,Vettori S,Balbir-Gurman A,Airò P,Walker U,Damjanov N,Matucci-Cerinic M,Ananieva LP,Rednic S,Czirják L,Distler O,Farge D,Hesselstrand R,Corrado A,Caramasc

更新日期：2019-01-01 00:00:00