Clonal analysis of B cells in the synovial membrane of patients with rheumatoid arthritis.

abstract：OBJECTIVE:To determine whether high-frequency ultrasound (US) yielding separate assessments of intima and media thickness gives additional information about the vascular morphology compared with the total common carotid artery intima-media thickness (CCA-IMT). METHODS:Using a 22 MHz US instrument, we determined the ne...

journal_title：Scandinavian journal of rheumatology

authors： Leonard D,Akhter T,Nordmark G,Rönnblom L,Naessen T

更新日期：2011-01-01 00:00:00

abstract：OBJECTIVES:Over the past few years researchers have suggested that vitamin D plays a diverse role in autoimmune diseases such as systemic lupus erythematosus (SLE). We sought to determine the prevalence and predictors of vitamin D deficiency in a cohort of non-supplemented female SLE patients from the Mediterranean reg...

journal_title：Scandinavian journal of rheumatology

authors： Muñoz-Ortego J,Torrente-Segarra V,Prieto-Alhambra D,Salman-Monte TC,Carbonell-Abello J

更新日期：2012-01-01 00:00:00

abstract：:Complement activation products, C9 and C3-containing circulating immune complexes (CIC), were evaluated in plasma and synovial fluid (SF) from patients with rheumatoid arthritis (RA) and osteoarthritis. C3 activation products and the fluid phase terminal complement complex were considerably elevated in SF from RA pati...

journal_title：Scandinavian journal of rheumatology

authors： Olmez U,Garred P,Mollnes TE,Harboe M,Berntzen HB,Munthe E

更新日期：1991-01-01 00:00:00

abstract：:In a series of 100 adult patients with definite rheumatoid arthritis of at most 3 years' duration and with no previous penicillamine, gold or systemic corticosteroid treatment, 50 patients were treated with D-penicillamine and 50 with gold for one yar. The dose of penicillamine was 600 mg daily. Sodium aurothiomalate ...

journal_title：Scandinavian journal of rheumatology

authors： Mäkisara P,Nissilä M,Kajander A,Martio J,von Essen R,Anttila P,Mäkisara GL

更新日期：1978-01-01 00:00:00

abstract：:Systemic lupus erythematosus (SLE) is an uncommon immunological disorder with multisystemic involvement. Neurological and neuropsychiatric manifestations in this disease are multifactorial and can involve any part of this system. We describe one patient presenting with spastic quadriparesis as an early clinical manife...

journal_title：Scandinavian journal of rheumatology

authors： Gupta A,Singh S,Singh P,Ahluwalia J,Rath S,Minz RW

更新日期：2003-01-01 00:00:00

abstract：OBJECTIVE:To determine the impact of a broad spectrum of different polymorphisms within the interleukin-10 (IL-10) promoter gene on disease susceptibility to primary Sjogren's syndrome (pSS), clinical manifestations, and autoantibody production. METHODS:We genotyped 111 unrelated German Caucasian patients with pSS and...

journal_title：Scandinavian journal of rheumatology

authors： Willeke P,Gaubitz M,Schotte H,Becker H,Domschke W,Schlüter B

更新日期：2008-07-01 00:00:00

abstract：:Biopsy specimens of human articular cartilage were taken from the caudal summits and from the posterior part of both epicondyles of the right lower femoral epiphysis of 20 individuals within 12 hours post mortem. 12 articular surfaces were normal and 8 included changes attributable to osteoarthrosis. In one individual...

journal_title：Scandinavian journal of rheumatology

authors： Bjelle A

更新日期：1977-01-01 00:00:00

abstract：OBJECTIVES:The results of previous studies on the association between bone mineral density (BMD) and chronic spinal syndromes have been contradictory. Therefore, we studied relative BMD measured by the metacarpal index (MCI) and its associations with chronic neck and low-back syndromes and diffuse idiopathic skeletal h...

journal_title：Scandinavian journal of rheumatology

authors： Haara MM,Arokoski JP,Kröger H,Kärkkäinen A,Manninen P,Knekt P,Impivaara O,Heliövaara M

更新日期：2007-11-01 00:00:00

abstract：OBJECTIVE:To evaluate the efficacy of the essential omega-6 fatty acid Gammalinolenic acid (GLA) on fatigue associated with primary Sjögren's syndrome. METHODS:Ninety patients with primary Sjögren's syndrome (with or without signs of autoimmunity) entered a 6-month double blind placebo-controlled randomised trial with...

journal_title：Scandinavian journal of rheumatology

authors： Theander E,Horrobin DF,Jacobsson LT,Manthorpe R

更新日期：2002-01-01 00:00:00

abstract：OBJECTIVES:Cationic lipid complexes bind to angiogenic endothelial cells of solid tumours and microvessels of chronic inflammatory tissue. Methotrexate (MTX) is one of the drugs used in the therapy of rheumatoid arthritis (RA); it is applied systemically but can have serious side-effects. The aim of this study was to i...

journal_title：Scandinavian journal of rheumatology

authors： Gottschalk O,Metz P,Dao Trong ML,Altenberger S,Jansson V,Mutschler W,Schmitt-Sody M

更新日期：2015-01-01 00:00:00

abstract：:106 women and 38 men suffering from definite or classical rheumatoid arthritis underwent a pulmonary function test. The results were correlated to the duration and various clinical activity parameters of the disease. Pulmonary diffusion capacity was found to be reduced compared with the predicted values (p less than 0...

journal_title：Scandinavian journal of rheumatology

authors： Oxholm P,Madsen EB,Manthorpe R,Rasmussen FV

更新日期：1982-01-01 00:00:00

abstract：OBJECTIVE:Aseptic loosening is one of the most important problems that can occur after total hip arthroplasty (THA). In this study, we analysed levels of large tenascin-C (TN-C) variants and compared them in pseudosynovial fluid from patients with aseptic loosening after THA with those in synovial fluid from patients u...

journal_title：Scandinavian journal of rheumatology

authors： Hasegawa M,Sudo A,Nagakura T,Hirata H,Kinoshita N,Yoshida T,Uchida A

更新日期：2005-11-01 00:00:00

abstract：:An account is given of a viscometer which can be used for measuring the viscosity of synovial fluid when only small quantities are avaliable (0.15 ml) and taking into account the non-Newtonian character of the fluid. A technical description of the apparatus is given. A series of experiments are reported in which bovin...

journal_title：Scandinavian journal of rheumatology

authors： Reimann I,Stougaard J,Northeved A

更新日期：1975-01-01 00:00:00

abstract：:A case of bilateral temporomandibular joint (TMJ) ankylosis in a Chinese male patient with ankylosing spondylitis is presented. A review of the literature emphasizes the rarity of this arthro-pathology in ankylosing spondylitis. The importance in the recognition of this complication by clinical examination supplemente...

journal_title：Scandinavian journal of rheumatology

authors： Chow TK,Ng WL,Tam CK,Kung N

更新日期：1997-01-01 00:00:00

abstract：:The effect of glycosaminoglycan polysulphate as medication for osteoarthritis was studied in an experimental model of osteoarthritis induced by periodic immobilization of rabbit knees. In a pilot experiment with 5 weeks of continuous immobilization there were indistinct differences between treated and control groups. ...

journal_title：Scandinavian journal of rheumatology

authors： Vanharanta H

更新日期：1983-01-01 00:00:00

abstract：:To determine the reliability of tender point assessment by manual palpation in patients with fibromyalgia, and to investigate the sources of variance, tender point scores by manual palpation were obtained in 30 fibromyalgia patients by 2 investigators; the assessments were repeated after 1 week. Test-retest stability ...

journal_title：Scandinavian journal of rheumatology

authors： Jacobs JW,Geenen R,van der Heide A,Rasker JJ,Bijlsma JW

更新日期：1995-01-01 00:00:00

abstract：:Thirty-four patients with Sjögren's syndrome were retrospectively examined in order to evaluate longitudinal alterations in objective ocular disease parameters and their possible relation to systemic bromhexine treatment. Twenty-three patients (68%) were initially found to respond to peroral bromhexine treatment and w...

journal_title：Scandinavian journal of rheumatology

authors： Kriegbaum NJ,von Linstow M,Oxholm P,Prause JU

更新日期：1989-01-01 00:00:00

abstract：OBJECTIVE:Chronic renal disease other than scleroderma renal crisis (SRC) is not well documented in systemic sclerosis (SSc). We examined the occurrence of decreased glomerular filtration rate (GFR) in a large consecutive SSc cohort and analysed whether it was related to SSc or could be related to other causes. METHOD...

journal_title：Scandinavian journal of rheumatology

authors： Scheja A,Bartosik I,Wuttge DM,Hesselstrand R

更新日期：2009-01-01 00:00:00

abstract：:SA 96 (N-(2-mercapto-2-methylpropanoyl)-L-cysteine) is a new sulfhydryl compound having a relatively similar chemical structure to Tiopronin and D-penicillamine. An open trial of SA 96 treatment (300 mg/day after meals for 16 weeks) was carried out in 11 patients with definite or classical rheumatoid arthritis and wit...

journal_title：Scandinavian journal of rheumatology

authors： Ishikawa K,Sakaguchi M

更新日期：1986-01-01 00:00:00

abstract：OBJECTIVE:To evaluate chromosome damage, by means of micronucleus frequency, in dermal fibroblasts from affected and non-affected skin from systemic sclerosis (SSc) patients and from controls. METHODS:Primary fibroblast cultures were obtained by biopsy from affected and non-affected skin from SSc patients. Control fib...

journal_title：Scandinavian journal of rheumatology

authors： Martins EP,Fuzzi HT,Kayser C,Alarcon RT,Rocha MG,Chauffaille ML,Andrade LE

更新日期：2010-01-01 00:00:00

abstract：:A patient with familial Pelger-Huet (PH) anomaly, which accompanied tuberculosis, and acute polyarthritis is described. Investigations surrounding this case suggests that the immunological abnormalities may be associated with the PH anomaly and the tuberculosis, and that the complications may be related to the develop...

journal_title：Scandinavian journal of rheumatology

authors： Suzuki N,Yasutake T,Ushiyama O,Hiida M,Ohta A,Yamaguchi M

更新日期：1995-01-01 00:00:00

abstract：:The differentiation between psoriatic arthritis and rheumatoid arthritis can be clinically difficult if there is no manifest psoriasis of skin or nail. In order to clarify this diagnostic problem, the amino acid patterns in seventy-five psoriatic and non-psoriatic nails have been studied. Using gas--liquid chromatogra...

journal_title：Scandinavian journal of rheumatology

authors： Greaves MS,Fieller NR,Moll JM

更新日期：1979-01-01 00:00:00

abstract：OBJECTIVES:To study the link between metabolic syndrome (MetS), endothelial injury, and atherosclerosis in patients with systemic lupus erythematosus (SLE). METHODS:Consecutive SLE patients without a history of arterial thrombosis were screened for atherosclerosis at the carotid and coronary arteries by B-mode ultraso...

journal_title：Scandinavian journal of rheumatology

authors： Mok CC,Poon WL,Lai JP,Wong CK,Chiu SM,Wong CK,Lun SW,Ko GT,Lam CW,Lam CS

更新日期：2010-01-01 00:00:00

abstract：:The synthesis and release of collagenase in the presence of the neuropeptide substance P (SP) and capsaicin, were investigated in vitro using identical synoviocyte cultures from patients with rheumatoid arthritis (RA). On average 10(-12) M SP augmented statistically significantly the collagenase production by approxim...

journal_title：Scandinavian journal of rheumatology

authors： Partsch G,Matucci-Cerinic M,Marabini S,Jantsch S,Pignone A,Cagnoni M

更新日期：1991-01-01 00:00:00

abstract：OBJECTIVES:We aimed to investigate the possible effects of vimentin (Vim) and citrullinated Vim (cVim) on proliferation capacity, pro-inflammatory cytokine secretion, and the expression of peptidylarginine deiminase type 4 (PADI4) and receptor activator of nuclear factor kappa B ligand (RANKL) in cultured fibroblast-li...

journal_title：Scandinavian journal of rheumatology

authors： Fan LY,He DY,Wang Q,Zong M,Zhang H,Yang L,Sun LS

更新日期：2012-10-01 00:00:00

abstract：OBJECTIVES:Thyroid dysfunction in the setting of systemic sclerosis (SSc) has been described previously. We aimed to determine the prevalence of anti-thyroid antibodies (ATA) in a large SSc cohort and to ascertain whether they are associated with distinct clinical phenotypes. METHODS:A total of 138 patients with SSc [...

journal_title：Scandinavian journal of rheumatology

authors： Danielides S,Mavragani CP,Katsakoulas I,Zintzaras E,Drosos AA,Vlachoyiannopoulos PG,Moutsopoulos HM

更新日期：2011-01-01 00:00:00

abstract：OBJECTIVES:To compare the risk of acute coronary syndrome (ACS) between patients with and without ankylosing spondylitis (AS). METHOD:This retrospective cohort study identified all patients with AS aged ≥ 18 years newly diagnosed from 2000 to 2009, registered in the National Health Insurance Research Database (NHIRD) ...

journal_title：Scandinavian journal of rheumatology

authors： Chou CH,Lin MC,Peng CL,Wu YC,Sung FC,Kao CH,Liu SH

更新日期：2014-01-01 00:00:00

abstract：OBJECTIVES:To determine the serum concentration of tumour necrosis factor (TNF)-related weak inducer of apoptosis (TWEAK) in patients with rheumatoid arthritis (RA) and to investigate the relationship between TWEAK level and disease activity, proinflammatory cytokine levels, and response to anti-TNF treatment. METHODS...

journal_title：Scandinavian journal of rheumatology

authors： Park MC,Chung SJ,Park YB,Lee SK

更新日期：2008-05-01 00:00:00

abstract：:The aim of this study was to evaluate the presence of PAF-acether (PAF), its specific degrading enzyme acetylhydrolase, and tumor necrosis factor (TNF) concentrations in blood and synovial fluid (SF) from patients with active RA. The variations of the mediators were also evaluated after corticosteroid perfusions in 7 ...

journal_title：Scandinavian journal of rheumatology

authors： Hilliquin P,Houbaba H,Aissa J,Benveniste J,Menkes CJ

更新日期：1995-01-01 00:00:00

abstract：OBJECTIVES:Progressive destruction of synovial joint cartilage and bone occurs in pathological conditions such as rheumatoid arthritis (RA) because of the overproduction of pro-inflammatory cytokines and activation of nuclear factor kappa B (NF-κB). Through the screening of NF-κB inhibitors by a luciferase reporter gen...

journal_title：Scandinavian journal of rheumatology

authors： Liu Q,Zhao J,Tan R,Zhou H,Lin Z,Zheng M,Romas E,Xu J,Sims NA

更新日期：2015-05-01 00:00:00