SA 96 (N-(2-mercapto-2-methylpropanoyl)-L-cysteine) in rheumatoid arthritis.

abstract：OBJECTIVE:To examine magnetic resonance imaging (MRI) scans for bone lesions typical of rheumatoid arthritis (RA) in the wrist joints of healthy individuals. METHODS:Thirty-one symptomless healthy persons (13/18 men/women), mean age 49 years (range 32-64 years), were included. MRI scans and radiographs of both wrists ...

journal_title：Scandinavian journal of rheumatology

authors： Palosaari K,Vuotila J,Soini I,Kaarela K,Kautiainen H,Hakala M

更新日期：2009-11-01 00:00:00

abstract：:The prognostically important signs and symptoms in the early stage of rheumatoid arthritis were studied in 136 patients selected and treated in Moscow and in 139 patients in Heinola, Finland. The follow-up time was 3 years. The outcome was poor in patients with early signs of radiological destruction in the joints, wi...

journal_title：Scandinavian journal of rheumatology

authors： Isomäki H,Martio J,Sarna S,Kiviniemi P,Akimova T,Ievleva L,Mylov N,Trofimova T

更新日期：1984-01-01 00:00:00

abstract：:An account is given of a viscometer which can be used for measuring the viscosity of synovial fluid when only small quantities are avaliable (0.15 ml) and taking into account the non-Newtonian character of the fluid. A technical description of the apparatus is given. A series of experiments are reported in which bovin...

journal_title：Scandinavian journal of rheumatology

authors： Reimann I,Stougaard J,Northeved A

更新日期：1975-01-01 00:00:00

abstract：:Objective: The aim of this study was to review the literature to identify studies reporting repair of erosions in rheumatoid arthritis (RA).Method: A systematic literature search for publications on the repair of erosions was performed in PubMed and Embase, limited to human adults and published in English. Titles, abs...

journal_title：Scandinavian journal of rheumatology

authors： Forslind K,Svensson B

更新日期：2019-11-01 00:00:00

abstract：OBJECTIVES:The aim of this study was to test whether orosomucoid like 3 (ORMDL3) and 17q21 variants are associated with susceptibility to ankylosing spondylitis (AS) in a Chinese population. METHOD:A total of 753 unrelated AS patients and 1120 ethnically matched healthy controls were recruited. Seven single nucleotide...

journal_title：Scandinavian journal of rheumatology

authors： Qiu R,Zhang H,Zhao H,Li J,Guo C,Gong Y,Liu Q

更新日期：2013-01-01 00:00:00

abstract：:Psychological and emotional status was assessed in 36 patients with systemic lupus erythematosus (SLE) with the General Health Questionnaire-30 (GHQ-30) and Minnesota Multiphasic Personality Inventory (MMPI) questionnaires. The two tests were found to measure different aspects of psychological functioning. More than 5...

journal_title：Scandinavian journal of rheumatology

authors： Waterloo K,Omdal R,Husby G,Mellgren SI

更新日期：1998-01-01 00:00:00

abstract：OBJECTIVE:Serum interleukin-18 (IL-18) levels are increased in patients with interstitial lung disease (ILD). In addition, IL-18 levels are increased in patients with rheumatoid arthritis (RA) and are associated with arthritis activity. We determined whether increased IL-18 levels are associated with ILD in RA. METHOD...

journal_title：Scandinavian journal of rheumatology

authors： Matsuo T,Hashimoto M,Ito I,Kubo T,Uozumi R,Furu M,Ito H,Fujii T,Tanaka M,Terao C,Kono H,Mori M,Hamaguchi M,Yamamoto W,Ohmura K,Morita S,Mimori T

更新日期：2019-03-01 00:00:00

abstract：:Levels of cyclic adenosine 3',5'-monophosphate (cAMP) and cyclic guanosine 3',5'-monophosphate (cGMP) have been investigated in joint fluid in inflammatory arthropathies. A disturbed balance between cAMP and cGMP due to a depressed level of cAMP was found in rheumatoid arthritis (RA) and Reiter's syndrome, in comparis...

journal_title：Scandinavian journal of rheumatology

authors： Trang LE,Lövgren O,Roch-Norlund AE,Horn RS,Walaas O

更新日期：1979-01-01 00:00:00

abstract：OBJECTIVES:The human urate transporter 1 (URAT1, encoded by SLC22A12) was recently identified as the major absorptive urate transporter protein in the kidney responsible for regulating blood urate levels. The present study was designed to investigate the rs893006 polymorphism (GG, GT, and TT) in SLC22A12 in a total of ...

journal_title：Scandinavian journal of rheumatology

authors： Guan M,Zhang J,Chen Y,Liu W,Kong N,Zou H

更新日期：2009-01-01 00:00:00

abstract：:The aim of the present study was to assess the T cell cytokines IFN-gamma, IL-2, IL-4 and IL-5 in labial salivary glands (LSG) in Sjögren's syndrome (SS) and healthy controls using RT-PCR and immunohistochemistry. IFN-gamma is always or almost always produced in SS and in healthy controls. IL-2 was also found in some ...

journal_title：Scandinavian journal of rheumatology

authors： Konttinen YT,Kemppinen P,Koski H,Li TF,Jumppanen M,Hietanen J,Santavirta S,Salo T,Larsson A,Hakala M,Sorsa T

更新日期：1999-01-01 00:00:00

abstract：:219 metatarsal (MTP) and 69 metacarpal (MCP) capitulae obtained during surgery from patients with definite rheumatoid arthritis (RA) were histologically evaluated. This evaluation, focussing on primary pathways of joint destruction by tumor-like proliferated synovial cell masses revealed 3 pathways of aggression: Path...

journal_title：Scandinavian journal of rheumatology

authors： Fassbender HG,Seibel M,Hebert T

更新日期：1992-01-01 00:00:00

abstract：OBJECTIVE:To determine the expression of bcl-2, p53, and caspase 3, and measure the Ki-67 proliferation index as well as DNA content and DNA fragmentation in a case of diffuse pigmented villonodular synovitis (PVNS) of the knee with aggressive clinical behaviour. METHODS:Expression of p53, Bcl-2 and Ki-67 was investig...

journal_title：Scandinavian journal of rheumatology

authors： Berger I,Paessler HH,Weckauf H,Ehemann V,Helmchen B

更新日期：2005-01-01 00:00:00

abstract：:We investigated the frequency of gut inflammation and the role of gut lesion in the pathogenesis of the ankylosing spondylitis (AS) in Korean patients. Ileocolonoscopy and biopsy of the colon and terminal ileum were performed on 24 Korean patients with AS. Endoscopic lesions were observed in 7 patients (29.2%). The le...

journal_title：Scandinavian journal of rheumatology

authors： Lee YH,Ji JD,Kim JS,Bak YT,Lee CH,Kim CH,Chae YS,Song GG

更新日期：1997-01-01 00:00:00

abstract：OBJECTIVE:To estimate the prevalence of spondyloarthropathies (SpA) in an adult population in Marche, a region located in central Italy. METHODS:A cross-sectional population-based study was conducted on a target adult population of 20 882. Questionnaires were sent to a random sample of 3664 individuals aged 18 years a...

journal_title：Scandinavian journal of rheumatology

authors： De Angelis R,Salaffi F,Grassi W

更新日期：2007-01-01 00:00:00

abstract：:An investigation has been carried out on the presence of iron in striated muscle from normal individuals and from patients with rheumatoid disease. The methods used for the estimation of iron required a neutron activation analysis of total iron and extraction of hemoglobin in cyanide buffer. The results disclosed that...

journal_title：Scandinavian journal of rheumatology

authors： Goldie IF,Bjönness T,Tiselius P,Plantin LO,Sato T

更新日期：1976-01-01 00:00:00

abstract：:Objectives: IgG4-related disease (IgG4-RD) may present as 'idiopathic' retroperitoneal fibrosis (IRPF). We aimed to determine the occurrence of IgG4-retroperitoneal fibrosis (IgG4-RPF) in a nationwide study on patients with newly diagnosed IRPF, and to compare histopathological, imaging, and clinical features in the I...

journal_title：Scandinavian journal of rheumatology

authors： Lomborg N,Jakobsen M,Bode CS,Junker P

更新日期：2019-07-01 00:00:00

abstract：:YKL-40, also called human cartilage glycoprotein-39, is a major secretory protein of human chondrocytes in cell culture. YKL-40 mRNA is expressed by cartilage from patients with rheumatoid arthritis, but is not detectable in normal human cartilage. The aim was to investigate the distribution of YKL-40 in osteoarthriti...

journal_title：Scandinavian journal of rheumatology

authors： Volck B,Ostergaard K,Johansen JS,Garbarsch C,Price PA

更新日期：1999-01-01 00:00:00

abstract：:Eight patients with a radiological diagnosis of Osteitis condensans ilii (OCI) had clinical features similar to those of 8 patients with sacro-iliitis (SI). The X-ray appearances may be very difficult to differentiate on standard films and discrimination between the two conditions has to be made from a combination of ...

journal_title：Scandinavian journal of rheumatology

authors： Withrington RH,Sturge RA,Mitchell N

更新日期：1985-01-01 00:00:00

abstract：OBJECTIVES:Progressive destruction of synovial joint cartilage and bone occurs in pathological conditions such as rheumatoid arthritis (RA) because of the overproduction of pro-inflammatory cytokines and activation of nuclear factor kappa B (NF-κB). Through the screening of NF-κB inhibitors by a luciferase reporter gen...

journal_title：Scandinavian journal of rheumatology

authors： Liu Q,Zhao J,Tan R,Zhou H,Lin Z,Zheng M,Romas E,Xu J,Sims NA

更新日期：2015-05-01 00:00:00

abstract：:Objective: Vasculopathy in systemic sclerosis (SSc) is characterized by the obliteration of arterioles and a reduced capillary density in various tissues. In SSc, atrophic alterations of the choroid have been suggested based on morphological data acquired by optical coherence tomography (OCT). In this study, we aimed ...

journal_title：Scandinavian journal of rheumatology

authors： Ranjbar M,Rothe M,Klapa S,Lange T,Prasuhn M,Grisanti S,Riemekasten G,Humrich JY

更新日期：2020-03-01 00:00:00

abstract：:Primary Sjögren's syndrome (pSS) is a connective tissue disease with symptoms and serological findings often overlapping with systemic lupus erythematosus (SLE) (1). Thromboembolic events are common in SLE but not in pSS (2)(3). However, case reports have described pSS patients who developed fulminant multiorgan disea...

journal_title：Scandinavian journal of rheumatology

authors： Haga HJ,Jacobsen EM,Peen E

更新日期：2008-03-01 00:00:00

abstract：OBJECTIVES:To evaluate the gustatory and olfactory functions of patients with rheumatoid arthritis (RA) compared to sex- and age-matched healthy subjects and to investigate a potential relationship between disease activity [using the 28-joint Disease Activity Score (DAS28)] and chemosensory capacity. Furthermore, to di...

journal_title：Scandinavian journal of rheumatology

authors： Steinbach S,Proft F,Schulze-Koops H,Hundt W,Heinrich P,Schulz S,Gruenke M

更新日期：2011-05-01 00:00:00

abstract：:Antibodies to soluble ribonucleoprotein (sRNP) are by definition a prerequisite for the diagnosis mixed connective tissue disease (MCTD). They are also found in 30--40% of other rheumatic conditions with a high titred speckled IFL reaction. The same is true for the most characteristic clinical features of MCTD, viz. R...

journal_title：Scandinavian journal of rheumatology

authors： Jonsson J,Norberg R

更新日期：1978-01-01 00:00:00

abstract：:To assess the role of crystal size in the biologic response, we quantitated the generation of reactive oxygen metabolites in human polymorphonuclear leukocytes (PMNs) or mononuclear leukocytes (MNs) with a chemiluminescence assay using 6 alpha-alumina preparations with average diameters of 0.6, 0.8, 3.2, 7.5, 28 and 6...

journal_title：Scandinavian journal of rheumatology

authors： Nagase M,Nishiya H,Takeuchi H

更新日期：1995-01-01 00:00:00

abstract：:46 patients who had an ulcer (verified by X-ray pictures) during treatment at the Rheumatism Foundation Hospital were compared with two patient groups of the same size. The first control group consisted of randomly selected patients who had been examined in the same way for the same indications but where the X-ray pic...

journal_title：Scandinavian journal of rheumatology

authors： Martio J

更新日期：1980-01-01 00:00:00

abstract：:Rheumatoid synovial tissue cell proliferation was studied by incubating fresh synovial tissue samples with [3H]-thymidine in vitro. The samples were collected at operation from 7 rheumatoid patients. It was found that 0.9-4.9% of the total cell population, excluding the synovial lining cells, became labelled. ...

journal_title：Scandinavian journal of rheumatology

authors： Nykänen PJ,Jyväsjärvi SH,Pätiälä HV

更新日期：1977-01-01 00:00:00

abstract：:The correlation among the various markers of activated T cells (soluble interleukin 2 receptor (sIL-2R), HLA-DR+ and HLA-DP+ T cells, proliferating cell nuclear antigen (PCNA) positive lymphocytes) were examined in patients with systemic lupus erythematosus (SLE), and related to the cell cycle. The concentration of sI...

journal_title：Scandinavian journal of rheumatology

authors： Tokano Y,Morimoto S,Hishikawa T,Murashima A,Abe M,Sekigawa I,Takasaki Y,Hashimoto H,Okumura K,Shirai T,Hirose S

更新日期：1997-01-01 00:00:00

abstract：:Ultrasound detects effusion and synovial proliferation caused by synovitis. The study was undertaken to evaluate the signs of synovitis in patients with primary Sjögren's Syndrome (SS). Joint effusion was detected and synovial thickness was measured in the suprapatellar synovial bursa. Results have been compared with ...

journal_title：Scandinavian journal of rheumatology

authors： Iagnocco A,Coari G,Palombi G,Valesini G

更新日期：2002-01-01 00:00:00

abstract：OBJECTIVES:Measurement of serum biomarkers at disease onset may improve prediction of disease course in patients with early rheumatoid arthritis (RA). We evaluated the multi-biomarker disease activity (MBDA) score and early changes in MBDA score for prediction of 28-joint Disease Activity Score based on C-reactive prot...

journal_title：Scandinavian journal of rheumatology

authors： Brahe CH,Østergaard M,Johansen JS,Defranoux N,Wang X,Bolce R,Sasso EH,Ørnbjerg LM,Hørslev-Petersen K,Stengaard-Pedersen K,Junker P,Ellingsen T,Ahlquist P,Lindegaard H,Linauskas A,Schlemmer A,Dam MY,Hansen I,Lottenburg

更新日期：2019-01-01 00:00:00

abstract：:We evaluated the efficacy and toxicity of cyclosporine A (CsA) in combination with methotrexate (MTX) or hydroxychloroquine (HCQ) in patients with refractory rheumatoid arthritis (RA). Fourteen patients with active RA who had failed to respond adequately to injectable MTX and 14 who had failed to respond to oral HCQ h...

journal_title：Scandinavian journal of rheumatology

authors： Salaffi F,Carotti M,Cervini C

更新日期：1996-01-01 00:00:00