Abstract:
:Rheumatoid synovial tissue cell proliferation was studied by incubating fresh synovial tissue samples with [3H]-thymidine in vitro. The samples were collected at operation from 7 rheumatoid patients. It was found that 0.9-4.9% of the total cell population, excluding the synovial lining cells, became labelled.
journal_name
Scand J Rheumatoljournal_title
Scandinavian journal of rheumatologyauthors
Nykänen PJ,Jyväsjärvi SH,Pätiälä HVdoi
10.3109/03009747709095429subject
Has Abstractpub_date
1977-01-01 00:00:00pages
103-4issue
2eissn
0300-9742issn
1502-7732journal_volume
6pub_type
杂志文章abstract:OBJECTIVES:To identify the magnetic resonance imaging (MRI) parameter that best differentiates healthy persons and patients with early rheumatoid arthritis (RA), and to investigated responsiveness to treatment of various MRI parameters. METHOD:Conventional MRI and dynamic contrast-enhanced (DCE)-MRI of the hand were p...
journal_title:Scandinavian journal of rheumatology
pub_type: 杂志文章
doi:10.3109/03009742.2013.824022
更新日期:2014-01-01 00:00:00
abstract:OBJECTIVES:Reactive arthritis (ReA) is a sterile joint inflammation triggered by a remote infection and associated with human leucocyte antigen (HLA)-B27. Its pathogenesis is unknown, but abnormal response to microbial structures or endogenous inflammatory mediators may be involved. We studied responses in leucocyte si...
journal_title:Scandinavian journal of rheumatology
pub_type: 杂志文章
doi:10.3109/03009742.2012.664649
更新日期:2012-08-01 00:00:00
abstract:OBJECTIVES:Giant cell arteritis (GCA) is a systemic disease with extensive vascular involvement. The aim of this study was to investigate the cumulative incidence of large vessel involvement (LVI) in GCA, the distribution of vessels involved, and predictors for LVI. METHOD:Patients with biopsy-proven GCA in a defined ...
journal_title:Scandinavian journal of rheumatology
pub_type: 杂志文章
doi:10.1080/03009742.2016.1190984
更新日期:2017-05-01 00:00:00
abstract::To investigate whether the therapeutic effect of etidronate is affected by the time of ingestion we have retrospectively studied 110 osteoporotic patients. They had been taking etidronate according to the manufacturer's instructions for a mean duration of 2.6 years either on waking (n=47), on retiring (n=47), or durin...
journal_title:Scandinavian journal of rheumatology
pub_type: 杂志文章
doi:10.1080/030097400750001824
更新日期:2000-01-01 00:00:00
abstract::In studies on 779 fresh, unselected ANA+ sera, 50 (6.4%) were found to have anti-dsDNA antibodies, by using CIP (C. luciliae immunoperoxidase), and 84% of the 50 patients met the criteria for definite SLE. After freezing 36 of these sera for 13 +/- 1 months, only 52.8% were again positive by CIP. Using CIF (C. lucilia...
journal_title:Scandinavian journal of rheumatology
pub_type: 杂志文章
doi:10.3109/03009748509102043
更新日期:1985-01-01 00:00:00
abstract::Thirty-four patients with Sjögren's syndrome were retrospectively examined in order to evaluate longitudinal alterations in objective ocular disease parameters and their possible relation to systemic bromhexine treatment. Twenty-three patients (68%) were initially found to respond to peroral bromhexine treatment and w...
journal_title:Scandinavian journal of rheumatology
pub_type: 杂志文章
doi:10.3109/03009748909099928
更新日期:1989-01-01 00:00:00
abstract::Protracted febrile myalgia (PFM) is a rare form of vasculitic disease that affects patients with familial Mediterranean fever (FMF). Mutation analysis performed in 15 patients who suffered from this disorder showed that 9 of the 15 patients were homozygous for M694V. FMF in these 9 patients was associated with more se...
journal_title:Scandinavian journal of rheumatology
pub_type: 杂志文章
doi:10.1080/030097400750002058
更新日期:2000-01-01 00:00:00
abstract:OBJECTIVES:To analyse the clinical features of Chinese undifferentiated spondyloarthritis (USpA) patients with predominantly axial involvement, and in particular the influence of human leucocyte antigen (HLA)-B27 and magnetic resonance imaging (MRI) of the sacroiliac joint (SIJ) on the classification of axial USpA. ME...
journal_title:Scandinavian journal of rheumatology
pub_type: 杂志文章
doi:10.3109/03009742.2011.585348
更新日期:2011-11-01 00:00:00
abstract:OBJECTIVES:To assess 12-month changes in nutritional status and quality of life (QoL) in systemic sclerosis (SSc) patients requiring home parenteral nutrition (HPN). METHOD:We conducted a retrospective, single-centre database analysis of SSc patients regarding a 12-month period of HPN at an interdisciplinary Universit...
journal_title:Scandinavian journal of rheumatology
pub_type: 杂志文章
doi:10.3109/03009742.2015.1064543
更新日期:2016-01-01 00:00:00
abstract:OBJECTIVE:FURIN is a proprotein convertase enzyme that inhibits the proinflammatory function of T cells and myeloid cells. Elevated FURIN expression levels have been reported in immune-mediated diseases, such as primary Sjögren's syndrome. Here, we investigated the levels of FURIN in peripheral blood (PB) and synovial ...
journal_title:Scandinavian journal of rheumatology
pub_type: 杂志文章
doi:10.1080/03009742.2018.1520294
更新日期:2019-05-01 00:00:00
abstract::Antigen-induced arthritis (AIA) was induced in adult rabbit knee joints, using ovalbumin as antigen. After 4 weeks, intra-articular injections of 0.3 ml 1% osmium tetroxide or 100 muCi 198Au were given. The same injections were also given to normal animals. The animals were observed for up to 12 weeks. In the normal a...
journal_title:Scandinavian journal of rheumatology
pub_type: 杂志文章
doi:
更新日期:1978-01-01 00:00:00
abstract:OBJECTIVE:Association with human leukocyte antigen (HLA)-DRB alleles, implicated in the aetiopathogenesis of rheumatoid arthritis (RA), is found to be different in various ethnic groups. This study aimed to investigate DRB1 alleles in RA patients in Turkey, and to examine the effect of these alleles on disease severity...
journal_title:Scandinavian journal of rheumatology
pub_type: 杂志文章
doi:10.1080/03009740310003901
更新日期:2003-01-01 00:00:00
abstract:OBJECTIVES:Patients with rheumatoid arthritis (RA) have a high risk of cardiovascular disease (CVD). Recent national and international guidelines suggest strict treatment of CVD risk factors in RA. The aim of this study was to evaluate the self-reported adherence to CV prevention strategies in patients with RA. METHOD...
journal_title:Scandinavian journal of rheumatology
pub_type: 杂志文章
doi:10.3109/03009742.2015.1028997
更新日期:2015-01-01 00:00:00
abstract::A radiological study of osteoarthrosis of the hips and knees has been performed in 364 female specialist physical education teachers, aged 46--60 years, who qualified between the years 1935 and 1950. The teachers were contacted by postal questionnaire and A.P. radiographs of the pelvis and knees were performed at a ho...
journal_title:Scandinavian journal of rheumatology
pub_type: 杂志文章
doi:10.3109/03009747909114633
更新日期:1979-01-01 00:00:00
abstract:OBJECTIVE:To study the frequence of deltoideal proximal insertion enthesitis (DPIE) in patients affected with spondyloarthritis (SpA) and to evaluate its clinical, sonographic and radiological characteristics. METHODS:A retrospective study of clinical, sonographic and radiological examinations of the shoulders of 100 ...
journal_title:Scandinavian journal of rheumatology
pub_type: 杂志文章
doi:
更新日期:2002-01-01 00:00:00
abstract:OBJECTIVE:To determine if calprotectin is predictive for outcome in patients with rheumatoid arthritis (RA). METHODS:Fifty six RA in-patients with variable disease duration were prospectively followed for five years. Clinical and laboratory data were collected to assess disease activity. Health Assessment Questionnair...
journal_title:Scandinavian journal of rheumatology
pub_type: 杂志文章
doi:10.1080/030097402320817077
更新日期:2002-01-01 00:00:00
abstract::Antibodies to soluble ribonucleoprotein (sRNP) are by definition a prerequisite for the diagnosis mixed connective tissue disease (MCTD). They are also found in 30--40% of other rheumatic conditions with a high titred speckled IFL reaction. The same is true for the most characteristic clinical features of MCTD, viz. R...
journal_title:Scandinavian journal of rheumatology
pub_type: 杂志文章
doi:10.3109/03009747809095661
更新日期:1978-01-01 00:00:00
abstract::The associations between the lumbar and femoral bone mineral and several body constitutional, lifestyle, and disease related variables were studied in 111 children with juvenile chronic arthritis (JCA) by factor and multiple linear regression analyses. In addition to the measurement of bone mineral density (BMD), bone...
journal_title:Scandinavian journal of rheumatology
pub_type: 杂志文章
doi:10.1080/03009749950155733
更新日期:1999-01-01 00:00:00
abstract::Levels of cyclic adenosine 3',5'-monophosphate (cAMP) and cyclic guanosine 3',5'-monophosphate (cGMP) have been investigated in joint fluid in inflammatory arthropathies. A disturbed balance between cAMP and cGMP due to a depressed level of cAMP was found in rheumatoid arthritis (RA) and Reiter's syndrome, in comparis...
journal_title:Scandinavian journal of rheumatology
pub_type: 杂志文章
doi:10.3109/03009747909105343
更新日期:1979-01-01 00:00:00
abstract:OBJECTIVES:The aims of this study were to measure the levels of interleukin (IL)-33 and ST2 and T-helper (Th)2-associated cytokines (IL-13, IL-4, IL-5) in patients with ankylosing spondylitis (AS), and examine the correlation of serum cytokine levels with disease activity and laboratory parameters. METHOD:Serum IL-33,...
journal_title:Scandinavian journal of rheumatology
pub_type: 杂志文章
doi:10.3109/03009742.2012.735700
更新日期:2013-01-01 00:00:00
abstract::Objectives: To study associations between different anthropometric measures and incident gout, and to find the best predictive measure. Method: We used the baseline investigation from the Malmö Diet and Cancer study, excluding cases of prevalent gout (n = 28 081). Cox regression for each anthropometric measurement was...
journal_title:Scandinavian journal of rheumatology
pub_type: 杂志文章
doi:10.1080/03009742.2019.1583368
更新日期:2019-07-01 00:00:00
abstract::A comparison of clinical, immunological and HLA-D region antigen features was made between 22 patients with mixed connective tissue disease (MCTD) and 118 patients with systemic lupus erythematosus (SLE), scleroderma or primary Sjögren's syndrome. The MCTD patients had hypergammaglobulinemia more often than did those ...
journal_title:Scandinavian journal of rheumatology
pub_type: 杂志文章
doi:10.3109/03009749309095117
更新日期:1993-01-01 00:00:00
abstract:OBJECTIVE:To evaluate chromosome damage, by means of micronucleus frequency, in dermal fibroblasts from affected and non-affected skin from systemic sclerosis (SSc) patients and from controls. METHODS:Primary fibroblast cultures were obtained by biopsy from affected and non-affected skin from SSc patients. Control fib...
journal_title:Scandinavian journal of rheumatology
pub_type: 杂志文章
doi:10.3109/03009741003685640
更新日期:2010-01-01 00:00:00
abstract::In a hospital population of 154 patients with a wide range of inflammatory rheumatic diseases, patients with sicca symptoms were subjected to objective ocular and oral tests to establish cases with Sjögren's syndrome (SS). The plasma level of the leukocyte protein calprotectin has been shown to be a good indicator of ...
journal_title:Scandinavian journal of rheumatology
pub_type: 杂志文章
doi:10.3109/03009749409103041
更新日期:1994-01-01 00:00:00
abstract::X-rays of 20 finger joints, 10 foot joints and 2 wrists of 50 female patients with seropositive rheumatoid arthritis of 10-15 years' duration from 1962, 1972, 1982 and 1992 were evaluated blindly for erosions. A highly significant decline was observed in erosions in finger joints. Erosions had also declined in wrists ...
journal_title:Scandinavian journal of rheumatology
pub_type: 杂志文章
doi:10.3109/03009749409102128
更新日期:1994-01-01 00:00:00
abstract:OBJECTIVES:To study the prevalence of comorbid conditions at diagnosis and during follow-up in a cohort of patients with early rheumatoid arthritis (RA) followed prospectively over 20 years, and to identify possible early predictive factors for future comorbidities. METHODS:A community-based cohort of 183 patients (me...
journal_title:Scandinavian journal of rheumatology
pub_type: 杂志文章
doi:10.3109/03009741003674180
更新日期:2010-01-01 00:00:00
abstract::Cyclic adenosine-3', 5'-monophosphate (cAMP) may influence important mechanisms in the inflammatory process, and fasting has been claimed to be clinically beneficial in rheumatoid arthritis (RA). A study was therefore designed to measure the concentrations of plasma cAMP in RA patients not undergoing drug treatment du...
journal_title:Scandinavian journal of rheumatology
pub_type: 杂志文章
doi:10.3109/03009748009112353
更新日期:1980-01-01 00:00:00
abstract:OBJECTIVES:Thyroid dysfunction in the setting of systemic sclerosis (SSc) has been described previously. We aimed to determine the prevalence of anti-thyroid antibodies (ATA) in a large SSc cohort and to ascertain whether they are associated with distinct clinical phenotypes. METHODS:A total of 138 patients with SSc [...
journal_title:Scandinavian journal of rheumatology
pub_type: 杂志文章
doi:10.3109/03009742.2010.549837
更新日期:2011-01-01 00:00:00
abstract::A case of gold-induced enterocolitis in a 69-year-old female with rheumatoid arthritis who had received the new gold compound by oral administration (Auranofin (AF) for 4 weeks) is reported. Mild diarrhoea is a commonly described side effect accompanying AF, but in this case a severe colitis developed. The course of t...
journal_title:Scandinavian journal of rheumatology
pub_type: 杂志文章
doi:10.3109/03009748309098544
更新日期:1983-01-01 00:00:00
abstract::Raynaud's phenomenon, digital ischemia, antinuclear antibodies and anticardiolipin antibodies are uncommon features of malignancy. The association of all of these in a patient with malignancy has not previously been reported. We describe a 52 year old woman with non small-cell carcinoma of the lung who also had Raynau...
journal_title:Scandinavian journal of rheumatology
pub_type: 杂志文章
doi:10.1080/030097401300162978
更新日期:2001-01-01 00:00:00