Protracted febrile myalgia of familial Mediterranean fever. Mutation analysis and clinical correlations.

abstract：:A technique for assessing the overall consequences of disease is introduced, comprising a Swedish version of a behaviour-based measure, the Sickness Impact Profile (SIP). Measurement characteristics of the profile are defined in an epidemiological study of 147 women with rheumatic disorders. The drop-out rate was 7.5%...

journal_title：Scandinavian journal of rheumatology

authors： Sullivan M,Ahlmén M,Archenholtz B,Svensson G

更新日期：1986-01-01 00:00:00

abstract：:Using the fluorescence polarization of 1.6-diphenyl-1, 3, 5-hexatriene, the membrane fluidity of lymphocytes obtained from rheumatoid arthritis patients was measured during 12 months of auranofin treatment. Significant differences in fluorescence polarization values were observed following auranofin treatment. The cor...

journal_title：Scandinavian journal of rheumatology

authors： Beccerica E,Piergiacomi G,Curatola G,Ferretti G

更新日期：1989-01-01 00:00:00

abstract：OBJECTIVE:To investigate the effects of TNF blocking therapy on synovial immune activity in rat adjuvant arthritis (AA) by measuring mRNA expression of key macrophage and T cell cytokines during PEG sTNF-RI treatment (10mg/kg) on days 8, 10 and 12. METHODS:Paw volume was assessed every 3-4 days. Ankles were removed fo...

journal_title：Scandinavian journal of rheumatology

authors： Bush KA,Walker JS,Frazier J,Kirkham BW

更新日期：2002-01-01 00:00:00

abstract：OBJECTIVE:To evaluate the effect of low-dose oral methotrexate (MTX) as treatment for patients with Kawasaki disease (KD) resistant to intravenous immunoglobulin (IVIG). METHODS:The subjects were four patients with KD, aged 8 months to 8 years old, who showed persistent disease after treatment with high-dose IVIG (2 g...

journal_title：Scandinavian journal of rheumatology

authors： Ahn SY,Kim DS

更新日期：2005-03-01 00:00:00

abstract：OBJECTIVE:To investigate the clonal characteristics of B cells in the synovial membranes of rheumatoid arthritis (RA) patients. METHODS:The clonality of B cells at separate sites of the synovial membrane and other tissues from RA patients were investigated by a reverse transcriptase-polymerase chain reaction with a VH...

journal_title：Scandinavian journal of rheumatology

authors： Shiokawa S,Matsumato N,Nishimura J

更新日期：2003-01-01 00:00:00

abstract：OBJECTIVE:To determine the effect of inflammation through exposure to tumour necrosis factor (TNF)alpha on T lymphocytes in patients with systemic lupus erythematosus (SLE). METHODS:We studied the effect of TNFalpha on T-lymphocyte apoptosis in patients with SLE, rheumatoid arthritis (RA), and in healthy controls. Apo...

journal_title：Scandinavian journal of rheumatology

authors： Habib HM,Taher TE,Isenberg DA,Mageed RA

更新日期：2009-03-01 00:00:00

abstract：OBJECTIVES:Calcium hydroxyapatite (HA) is reported to be the major constituent of soft tissue calcinosis in patients with scleroderma (systemic sclerosis, SSc). Mechanical stress and local tissue hypoxia are thought to be important in the pathogenesis of SSc calcinosis. We sought to analyse spontaneously draining mater...

journal_title：Scandinavian journal of rheumatology

authors： Hsu VM,Emge T,Schlesinger N

更新日期：2017-03-01 00:00:00

abstract：OBJECTIVES:Sarcoidosis is a chronic granulomatous disease. Pyrin has anti-inflammatory activity in the regulation of inflammasomes and is encoded by the Mediterranean fever (MEFV) gene. MEFV gene mutations trigger the inflammatory cascade and cause familial Mediterranean fever (FMF). A relationship between various rheu...

journal_title：Scandinavian journal of rheumatology

authors： Sever F,Kobak S,Goksel Ö,Goksel T,Orman M,Berdeli A

更新日期：2016-01-01 00:00:00

abstract：OBJECTIVE:To evaluate chromosome damage, by means of micronucleus frequency, in dermal fibroblasts from affected and non-affected skin from systemic sclerosis (SSc) patients and from controls. METHODS:Primary fibroblast cultures were obtained by biopsy from affected and non-affected skin from SSc patients. Control fib...

journal_title：Scandinavian journal of rheumatology

authors： Martins EP,Fuzzi HT,Kayser C,Alarcon RT,Rocha MG,Chauffaille ML,Andrade LE

更新日期：2010-01-01 00:00:00

abstract：:The distribution of messenger RNA coding for substance P receptor (NK1) in rheumatoid synovia and the relationship between signal intensity of NK1 mRNA and clinical parameters of disease activity were investigated. The synovia from 10 patients with rheumatoid arthritis (RA) and 7 patients with osteoarthritis was inves...

journal_title：Scandinavian journal of rheumatology

authors： Sakai K,Matsuno H,Tsuji H,Tohyama M

更新日期：1998-01-01 00:00:00

abstract：:Primary cultures of neonatal dermal fibroblasts from two strains of mice (A/J and C57BL6/J) were utilized as an in vitro system to investigate the effects of glucocorticoids on cell growth and collagen synthesis. Protein and DNA synthesis were lower in untreated (control) A/J fibroblasts than in C57BL6/J fibroblasts. ...

journal_title：Scandinavian journal of rheumatology

authors： Verbruggen LA,Orloff S,Rao VH,Salomon DS

更新日期：1983-01-01 00:00:00

abstract：:In 9 patients with active rheumatoid arthritis we studied gastrointestinal blood loss during well tolerated therapy with the non-steroidal anti-inflammatory drug naproxen, 500 mg twice daily. The mean gastrointestinal blood loss, assessed with reinfused autologous 51Cr-labelled erythrocytes, was 1.4 +/- 0.6 ml/day (me...

journal_title：Scandinavian journal of rheumatology

authors： van den Ouweland FA,Corstens FH,van de Putte LB,Gribnau FW

更新日期：1987-01-01 00:00:00

abstract：OBJECTIVES:The human urate transporter 1 (URAT1, encoded by SLC22A12) was recently identified as the major absorptive urate transporter protein in the kidney responsible for regulating blood urate levels. The present study was designed to investigate the rs893006 polymorphism (GG, GT, and TT) in SLC22A12 in a total of ...

journal_title：Scandinavian journal of rheumatology

authors： Guan M,Zhang J,Chen Y,Liu W,Kong N,Zou H

更新日期：2009-01-01 00:00:00

abstract：OBJECTIVES:Thyroid dysfunction in the setting of systemic sclerosis (SSc) has been described previously. We aimed to determine the prevalence of anti-thyroid antibodies (ATA) in a large SSc cohort and to ascertain whether they are associated with distinct clinical phenotypes. METHODS:A total of 138 patients with SSc [...

journal_title：Scandinavian journal of rheumatology

authors： Danielides S,Mavragani CP,Katsakoulas I,Zintzaras E,Drosos AA,Vlachoyiannopoulos PG,Moutsopoulos HM

更新日期：2011-01-01 00:00:00

abstract：OBJECTIVE:To compare the efficacy of adalimumab, etanercept, and infliximab in patients with established rheumatoid arthritis (RA) taking concomitant methotrexate (MTX) by calculating the number needed to treat (NNT) using three different methods. METHODS:A systematic literature search of the Cochrane Library, MEDLINE...

journal_title：Scandinavian journal of rheumatology

authors： Kristensen LE,Christensen R,Bliddal H,Geborek P,Danneskiold-Samsøe B,Saxne T

更新日期：2007-11-01 00:00:00

abstract：:SA 96 (N-(2-mercapto-2-methylpropanoyl)-L-cysteine) is a new sulfhydryl compound having a relatively similar chemical structure to Tiopronin and D-penicillamine. An open trial of SA 96 treatment (300 mg/day after meals for 16 weeks) was carried out in 11 patients with definite or classical rheumatoid arthritis and wit...

journal_title：Scandinavian journal of rheumatology

authors： Ishikawa K,Sakaguchi M

更新日期：1986-01-01 00:00:00

abstract：:In studies on 779 fresh, unselected ANA+ sera, 50 (6.4%) were found to have anti-dsDNA antibodies, by using CIP (C. luciliae immunoperoxidase), and 84% of the 50 patients met the criteria for definite SLE. After freezing 36 of these sera for 13 +/- 1 months, only 52.8% were again positive by CIP. Using CIF (C. lucilia...

journal_title：Scandinavian journal of rheumatology

authors： Lee TK,Rothberger H

更新日期：1985-01-01 00:00:00

abstract：:Synovectomy of 20 wrist joints in 15 patients with juvenile chronic arthritis (JCA) was performed and results were evaluated 3 (0.5-5) years after surgery. The surgical procedure consisted of synovectomy of the radiocarpal joint, around the ulnar head and in all intercarpal joints. Resection of the ulnar head was not ...

journal_title：Scandinavian journal of rheumatology

authors： Hanff G,Sollerman C,Elborgh R,Pettersson H

更新日期：1990-01-01 00:00:00

abstract：OBJECTIVE:To estimate the heritability of Kashin-Beck disease (KBD) in first-degree relatives and to identify chromosome regions likely to contain susceptibility loci for KBD. METHODS:A total of 331 probands with confirmed KBD in their pedigrees were selected from 9331 residents in 17 KBD villages of Linyou county, no...

journal_title：Scandinavian journal of rheumatology

authors： Shi XW,Guo X,Lv AL,Kang L,Zhou YL,Zhang YZ,Wu XM,Bai YD

更新日期：2010-05-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to analyse differences in clinical presentation in patients with early (< 3 years' duration) systemic sclerosis (SSc), comparing three age groups according to disease subsets. METHOD:Cross-sectional analysis of the prospective EULAR Scleroderma Trials and Research database (EUSTAR) ...

journal_title：Scandinavian journal of rheumatology

authors： Carreira PE,Carmona L,Joven BE,Loza E,Andréu JL,Riemekasten G,Vettori S,Balbir-Gurman A,Airò P,Walker U,Damjanov N,Matucci-Cerinic M,Ananieva LP,Rednic S,Czirják L,Distler O,Farge D,Hesselstrand R,Corrado A,Caramasc

更新日期：2019-01-01 00:00:00

abstract：:Fifty consecutive patients with RA and clinical wrist synovitis were randomly allocated to either receive an injection of glucocorticoid into the radiocarpal joint or have the same amount of drug divided into the radiocarpal and midcarpal joints. Inferior radioulnar joint synovitis was treated with extra steroid injec...

journal_title：Scandinavian journal of rheumatology

authors： Koski JM,Hermunen H

更新日期：2001-01-01 00:00:00

abstract：:The risk of a disease flare-up and the side-effects experienced during the use of oral contraceptives (OCs) were studied in 85 female SLE patients, 18-44 years old, regularly attending two specialist rheumatological clinics. Thirty-one patients had used combined oral contraceptives (cOCs) during or after the onset of ...

journal_title：Scandinavian journal of rheumatology

authors： Julkunen HA

更新日期：1991-01-01 00:00:00

abstract：:A total of 62 rheumatoid knee joints were treated with intra-articular 90Y. Results were assessed by clinical, roentgenologic and thermographic examination after a six-month follow-up. The majority of the joints had moderate roentgenologic manifestations of RA before treatment. The roentgenologic stage of the disease ...

journal_title：Scandinavian journal of rheumatology

authors： Jalava S,Räsänen O

更新日期：1975-01-01 00:00:00

abstract：:Objective: Erosion healing in rheumatoid arthritis (RA) is difficult to demonstrate. This extension study aimed to determine whether 2 years of teriparatide (TPTD) produces erosion healing. Method: Subjects in a previous 12 month randomized controlled trial of TPTD in RA were invited to receive 12 additional months of...

journal_title：Scandinavian journal of rheumatology

authors： Duryea J,Gravallese EM,Wortman JR,Xu C,Lu B,Kay J,Solomon DH

更新日期：2021-01-01 00:00:00

abstract：:Eight patients with a radiological diagnosis of Osteitis condensans ilii (OCI) had clinical features similar to those of 8 patients with sacro-iliitis (SI). The X-ray appearances may be very difficult to differentiate on standard films and discrimination between the two conditions has to be made from a combination of ...

journal_title：Scandinavian journal of rheumatology

authors： Withrington RH,Sturge RA,Mitchell N

更新日期：1985-01-01 00:00:00

abstract：:It is thought that glucocorticosteroids impair the clearance of immune complexes by the mononuclear phagocyte system (MPS). We studied the effect of a five day course of prednisone (1 mg/kg body weight per day) on MPS function in 10 healthy volunteers, using soluble radiolabeled aggregates of human immunoglobulin G as...

journal_title：Scandinavian journal of rheumatology

authors： Halma C,Daha MR,Evers-Schouten JH,Pauwels EK,van Es LA

更新日期：1992-01-01 00:00:00

abstract：:We report the case of a 41-year-old man diagnosed with Still's disease. Multiple disease-modifying anti-rheumatic drug (DMARD) therapies failed to induce disease remission or to prevent progressive joint destruction. The man presented with active arthritis and classical Still's rash accompanied by fever. Anti-tumour n...

journal_title：Scandinavian journal of rheumatology

authors： Thonhofer R,Soleiman A,Kriessmayr M,Thonhofer U,Wipfler E,Gaugg M,Eder S,Erlacher L

更新日期：2006-11-01 00:00:00

abstract：OBJECTIVES:Rheumatoid arthritis (RA) is a systemic, inflammatory disease. Renal involvement worsens the course of RA and increases mortality. It is suggested that chronic inflammatory processes may contribute to renal impairment. The aim of this study was to investigate the impact of chronic inflammation and RA activit...

journal_title：Scandinavian journal of rheumatology

authors： Targońska-Stepniak B,Majdan M

更新日期：2011-01-01 00:00:00

abstract：OBJECTIVE:To investigate changes in whole-body magnetic resonance imaging (WBMRI) inflammatory and structural lesions in most joints and entheses in patients with rheumatoid arthritis (RA) treated with adalimumab. METHODS:WBMRI was obtained at weeks 0, 6, 16, and 52 in a 52 week follow-up study of 37 RA patients start...

journal_title：Scandinavian journal of rheumatology

authors： Axelsen MB,Eshed I,Østergaard M,Hetland ML,Møller JM,Jensen DV,Krintel SB,Hansen MS,Terslev L,Klarlund M,Poggenborg RP,Balding L,Pedersen SJ

更新日期：2017-07-01 00:00:00

abstract：:To compare the state of dentition between rheumatoid and control patients, ortopanthomograms were taken of 126 rheumatoid and 119 control patients. This roenthenologic examination revealed a signficantly higher incidence of teeth loss among the rheumatoid patients than among the control patients. To determine whether ...

journal_title：Scandinavian journal of rheumatology

authors： Malmström M,Calonius PE

更新日期：1975-01-01 00:00:00