The time of day that etidronate is ingested does not influence its therapeutic effect in osteoporosis.

Abstract:

:To investigate whether the therapeutic effect of etidronate is affected by the time of ingestion we have retrospectively studied 110 osteoporotic patients. They had been taking etidronate according to the manufacturer's instructions for a mean duration of 2.6 years either on waking (n=47), on retiring (n=47), or during the day (n= 16). No significant differences were found between the three groups with respect to percentage change in bone mineral density at all sites either for the first year of treatment or for the mean yearly percent change throughout the total course of treatment. These findings suggest that the time of ingestion of etidronate does not influence the therapeutic effect if a two hour fast before and after ingestion is adhered to.

journal_name

Scand J Rheumatol

authors

Cook GJ,Blake GM,Fogelman I

doi

10.1080/030097400750001824

keywords:

subject

Has Abstract

pub_date

2000-01-01 00:00:00

pages

62-4

issue

1

eissn

0300-9742

issn

1502-7732

journal_volume

29

pub_type

杂志文章
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    doi:10.1080/03009740310003901

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    更新日期:2003-01-01 00:00:00

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