Auranofin (SK + F 39162) induced enterocolitis in rheumatoid arthritis. A case report.

Abstract:

:A case of gold-induced enterocolitis in a 69-year-old female with rheumatoid arthritis who had received the new gold compound by oral administration (Auranofin (AF) for 4 weeks) is reported. Mild diarrhoea is a commonly described side effect accompanying AF, but in this case a severe colitis developed. The course of this case is very similar to those reported regarding Myochrysin. The pathogenesis is discussed. It might be a direct toxic effect on the mucosa of the bowel, evidenced by the relatively high excretion of oral gold with faeces.

journal_name

Scand J Rheumatol

authors

Jarner D,Nielsen AM

doi

10.3109/03009748309098544

subject

Has Abstract

pub_date

1983-01-01 00:00:00

pages

254-6

issue

3

eissn

0300-9742

issn

1502-7732

journal_volume

12

pub_type

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