Pain analysis in patients with fibromyalgia. Effects of intravenous morphine, lidocaine, and ketamine.

Abstract:

:Pain intensity, muscle strength, static muscle endurance, pressure pain threshold, and pain tolerance at tender points and control points were assessed in 31 patients with fibromyalgia (FM), before and after intravenous administration of morphine (9 patients), lidocaine (11 patients), and ketamine (11 patients). The three different studies were double-blind and placebo-controlled. The patients were classified as placebo-responders, responders (decrease in pain intensity by > 50%) and non-responders. The morphine test did not show any significant changes. The lidocaine test showed a pain decrease during and after the infusion. The ketamine test showed a significant reduction in pain intensity during and after the test period. Tenderness at tender points decreased and endurance increased significantly, while muscle strength remained unchanged. The present results support the hypothesis that the NMDA receptors are involved in pain mechanisms in fibromyalgia. These findings also suggest that central sensitization is present in FM and that tender points represent secondary hyperalgesia.

journal_name

Scand J Rheumatol

authors

Sörensen J,Bengtsson A,Bäckman E,Henriksson KG,Bengtsson M

doi

10.3109/03009749509095181

subject

Has Abstract

pub_date

1995-01-01 00:00:00

pages

360-5

issue

6

eissn

0300-9742

issn

1502-7732

journal_volume

24

pub_type

临床试验,杂志文章,随机对照试验
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    abstract::The differentiation between psoriatic arthritis and rheumatoid arthritis can be clinically difficult if there is no manifest psoriasis of skin or nail. In order to clarify this diagnostic problem, the amino acid patterns in seventy-five psoriatic and non-psoriatic nails have been studied. Using gas--liquid chromatogra...

    journal_title:Scandinavian journal of rheumatology

    pub_type: 杂志文章

    doi:

    authors: Greaves MS,Fieller NR,Moll JM

    更新日期:1979-01-01 00:00:00

  • (D)-penicillamine treatment in systemic sclerosis (scleroderma). Effect on nutritional capillary circulation.

    abstract::Four patients with systemic sclerosis (scleroderma) were treated with (D)-penicillamine (1.2-1.8 g/d) for 18-60 months. All patients improved. Vital capillary microscopy demonstrated that the number of visible skin capillaries increased during therapy, thus indicating a more efficient nutritional circulation. ...

    journal_title:Scandinavian journal of rheumatology

    pub_type: 杂志文章

    doi:10.3109/03009747709095427

    authors: Mellstedt H,Fagrell B,Holm G,Björkholm M

    更新日期:1977-01-01 00:00:00

  • Autoantibodies to IL-1 alpha in sera from umbilical cords, children, and adults, and from patients with juvenile chronic arthritis.

    abstract::Antibodies against interleukin-1 alpha (aAb-IL-1 alpha) have previously been demonstrated in sera of healthy adults and in patients with inflammatory diseases. In the present investigation the occurrence of aAb-IL-1 alpha was examined by second antibody precipitation technique in sera from umbilical cords (n = 11), ch...

    journal_title:Scandinavian journal of rheumatology

    pub_type: 杂志文章

    doi:10.3109/03009749609080008

    authors: Müller K,Hansen MB,Zak M,Nielsen S,Pedersen FK,de Nully P,Bendtzen K

    更新日期:1996-01-01 00:00:00

  • Home parenteral nutrition is beneficial in systemic sclerosis patients with gastrointestinal dysfunction.

    abstract:OBJECTIVES:To assess 12-month changes in nutritional status and quality of life (QoL) in systemic sclerosis (SSc) patients requiring home parenteral nutrition (HPN). METHOD:We conducted a retrospective, single-centre database analysis of SSc patients regarding a 12-month period of HPN at an interdisciplinary Universit...

    journal_title:Scandinavian journal of rheumatology

    pub_type: 杂志文章

    doi:10.3109/03009742.2015.1064543

    authors: Stanga Z,Aeberhard C,Schärer P,Kocher A,Adler S,Villiger PM

    更新日期:2016-01-01 00:00:00

  • T(H)1 cytokines are produced in labial salivary glands in Sjögren's syndrome, but also in healthy individuals.

    abstract::The aim of the present study was to assess the T cell cytokines IFN-gamma, IL-2, IL-4 and IL-5 in labial salivary glands (LSG) in Sjögren's syndrome (SS) and healthy controls using RT-PCR and immunohistochemistry. IFN-gamma is always or almost always produced in SS and in healthy controls. IL-2 was also found in some ...

    journal_title:Scandinavian journal of rheumatology

    pub_type: 杂志文章

    doi:10.1080/030097499442577

    authors: Konttinen YT,Kemppinen P,Koski H,Li TF,Jumppanen M,Hietanen J,Santavirta S,Salo T,Larsson A,Hakala M,Sorsa T

    更新日期:1999-01-01 00:00:00

  • Renal function is mostly preserved in patients with systemic sclerosis.

    abstract:OBJECTIVE:Chronic renal disease other than scleroderma renal crisis (SRC) is not well documented in systemic sclerosis (SSc). We examined the occurrence of decreased glomerular filtration rate (GFR) in a large consecutive SSc cohort and analysed whether it was related to SSc or could be related to other causes. METHOD...

    journal_title:Scandinavian journal of rheumatology

    pub_type: 杂志文章

    doi:10.1080/03009740802629424

    authors: Scheja A,Bartosik I,Wuttge DM,Hesselstrand R

    更新日期:2009-01-01 00:00:00

  • Does the content really matter? A study comparing structure, process, and outcome of team rehabilitation for patients with inflammatory arthritis in two different clinical settings.

    abstract:OBJECTIVES:To provide a thorough description of team rehabilitation care and compare the structure, process, and outcomes in two specialized arthritis rehabilitation settings. METHODS:Patients with inflammatory arthritis scheduled for inpatient rehabilitation in seven specialized rehabilitation centres and three rheum...

    journal_title:Scandinavian journal of rheumatology

    pub_type: 杂志文章,多中心研究

    doi:10.3109/03009742.2011.601757

    authors: Klokkerud M,Hagen KB,Løchting I,Uhlig T,Kjeken I,Grotle M

    更新日期:2012-02-01 00:00:00

  • Zinc: its relationship to osteoporosis in rheumatoid arthritis.

    abstract::Preliminary studies indicate that plasma zinc concentrations, as estimated by atomic absorption spectrophotometry, are reduced in rheumatoid arthritis. A relationship has also been established between metacarpal index of osteoporosis and plasma zinc concentrations in rheumatoid subjects. ...

    journal_title:Scandinavian journal of rheumatology

    pub_type: 杂志文章

    doi:10.3109/03009747509165264

    authors: Kennedy AC,Fell GS,Rooney PJ,Stevens WH,Dick WC,Buchanan WW

    更新日期:1975-01-01 00:00:00

  • The value of the diagnostic criteria in rheumatoid arthritis.

    abstract::The ARA and the New York diagnostic criteria for rheumatoid arthritis were studied in 411 patients with a recent inflammatory joint disease (100 with RA, 311 with other disease) in order to evaluate their value in distinguishing progressive rheumatoid arthritis from other joint diseases. Rheumatoid factor, symmetrical...

    journal_title:Scandinavian journal of rheumatology

    pub_type: 杂志文章

    doi:10.3109/03009748309102003

    authors: Kaarela K,Hämeenkorpi R,Isomäki H

    更新日期:1983-01-01 00:00:00

  • Cytokine production (IL-6 and TNF alpha) in whole blood cell cultures of patients with systemic lupus erythematosus.

    abstract::Whole blood cell culture has great advantage over isolated peripheral blood mononuclear cell culture, because it needs only small amounts of blood and is fast to perform. The current report focuses on the measurement of IL-6 and TNF alpha produced by peripheral blood monocytes of patients with systemic lupus erythemat...

    journal_title:Scandinavian journal of rheumatology

    pub_type: 杂志文章

    doi:10.3109/03009749609069992

    authors: Swaak AJ,van den Brink HG,Aarden LA

    更新日期:1996-01-01 00:00:00

  • Osmium deposits detected by x-ray after synoviorthesis of the knee.

    abstract::A study of 113 knees of 72 patients treated with intra-articular injection of osmic acid for chronic exudative synovitis caused by various rheumatic diseases is reported. Certain cases presented abnormal radiological opacities, statistically more frequent after the injection of 200 mg than after 100 mg of osmic acid (...

    journal_title:Scandinavian journal of rheumatology

    pub_type: 杂志文章

    doi:

    authors: Boussina I,Lagier R,Ott H,Fallet GH

    更新日期:1976-01-01 00:00:00

  • The time of day that etidronate is ingested does not influence its therapeutic effect in osteoporosis.

    abstract::To investigate whether the therapeutic effect of etidronate is affected by the time of ingestion we have retrospectively studied 110 osteoporotic patients. They had been taking etidronate according to the manufacturer's instructions for a mean duration of 2.6 years either on waking (n=47), on retiring (n=47), or durin...

    journal_title:Scandinavian journal of rheumatology

    pub_type: 杂志文章

    doi:10.1080/030097400750001824

    authors: Cook GJ,Blake GM,Fogelman I

    更新日期:2000-01-01 00:00:00

  • Significance of C-reactive protein elevation in the pretreatment stage of systemic lupus erythematosus.

    abstract::The significance of C-reactive protein (CRP) elevation in patients with systemic lupus erythematosus (SLE) in the pretreatment stage was assessed with reference to other laboratory data obtained simultaneously. Sixteen of 31 cases were CRP-positive, and the CR-positive group contained significantly more cases with uri...

    journal_title:Scandinavian journal of rheumatology

    pub_type: 杂志文章

    doi:10.3109/03009748109095302

    authors: Inoue T,Kanayama Y,Katoh N,Ohe A,Amatsu K,Okamura M,Horiguchi T

    更新日期:1981-01-01 00:00:00

  • Arthroscopic volume of the knee joint in young male adults.

    abstract::'Arthroscopic volume' and resorption of normal saline was measured in 35 young males during routine arthroscopic examination. The average mean volume of the knee joint cavity was 103.4 ml and this volume was observed to correlate with the midpatellar circumference of the knee and the height of the patients. Mean resor...

    journal_title:Scandinavian journal of rheumatology

    pub_type: 杂志文章

    doi:10.3109/03009748609092587

    authors: Visuri T,Kiviluoto O

    更新日期:1986-01-01 00:00:00

  • Involvement of the lateral atlanto-axial joints as first and late symptom of rheumatoid arthritis.

    abstract::Thirty cases of unilateral or bilateral atlanto-axial arthritis are described. They were found among 606 RA patients. According to the degree of involvement, the 30 cases were divided into four groups: A. 16 cases. B. 5 cases. C. 7 cases. D. 2 cases. In two patients the atlanto-axial arthritis was the primary lesion. ...

    journal_title:Scandinavian journal of rheumatology

    pub_type: 杂志文章

    doi:10.3109/03009747009165372

    authors: Kerckhove HV

    更新日期:1987-01-01 00:00:00

  • Churg-Strauss syndrome presenting with pulmonary capillaritis and diffuse alveolar hemorrhage.

    abstract::Churg-Strauss syndrome (CSS) is a rare disorder characterized by the histopathological triad of systemic necrotizing vasculitis, extravascular granuloma, and eosinophilic infiltrate, occurring in individuals with asthma or a history of allergy. We report a case of CSS with rare presentation of diffuse pulmonary hemorr...

    journal_title:Scandinavian journal of rheumatology

    pub_type: 杂志文章

    doi:10.1080/030097498440877

    authors: Lai RS,Lin SL,Lai NS,Lee PC

    更新日期:1998-01-01 00:00:00

  • Culture of joint specimens in bacterial arthritis. Impact of blood culture bottle utilization.

    abstract::The advantage of inoculating blood culture bottles (BCB) with a bulk volume of joint fluid was studied by analyzing results for 155 positive specimens cultured in parallel in BCB and on conventional solid media. The specimens came from both natural and artificial joints of 89 patients treated in 1975-1994. One third o...

    journal_title:Scandinavian journal of rheumatology

    pub_type: 杂志文章

    doi:10.3109/03009749709105319

    authors: von Essen R

    更新日期:1997-01-01 00:00:00

  • In vivo interactions of platelets and leucocytes with the endothelium in murine antigen-induced arthritis: the role of P-selectin.

    abstract:OBJECTIVE:Platelets are thought to participate in the pathogenesis of chronic inflammatory diseases such as rheumatoid arthritis (RA). We showed recently an in vivo increase in platelet-endothelial cell interactions in mice with antigen-induced arthritis (AiA). The underlying mechanisms are not yet clear. The aim of th...

    journal_title:Scandinavian journal of rheumatology

    pub_type: 杂志文章

    doi:10.1080/03009740701218741

    authors: Schmitt-Sody M,Metz P,Klose A,Gottschalk O,Zysk S,Hausdorf J,Veihelmann A,Jansson V

    更新日期:2007-07-01 00:00:00

  • Cyclic nucleotides and catecholamines in rheumatoid arthritis.

    abstract::A controlled cross over study on the effect of fasting on cyclic nucleotide and catecholamine excretion was carried out in 12 female RA patients. They were hospitalized during a control and fasting period. The fasting period started with 3 days of habituation to hospital conditions, followed by 7 days of total fasting...

    journal_title:Scandinavian journal of rheumatology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.3109/03009748309102906

    authors: Trang LE,Lövgren O,Norlund AE,Horn R,Walaas O

    更新日期:1983-01-01 00:00:00

  • Plant thorn synovitis diagnosed by magnetic resonance imaging.

    abstract::Plant thorn synovitis is an overlooked cause of monoarthritis, with difficulties in diagnosis and treatment (1). We report on a case of thorn induced synovitis, not confirmed by histopathology, but strongly suspected by magnetic resonance imaging (MRI), that visualizes the foreign body (first case reported). ...

    journal_title:Scandinavian journal of rheumatology

    pub_type: 杂志文章

    doi:10.3109/03009749409103051

    authors: Maillot F,Goupille P,Valat JP

    更新日期:1994-01-01 00:00:00

  • Healing of erosions in rheumatoid arthritis remains elusive: results with 24 months of the anabolic agent teriparatide.

    abstract::Objective: Erosion healing in rheumatoid arthritis (RA) is difficult to demonstrate. This extension study aimed to determine whether 2 years of teriparatide (TPTD) produces erosion healing. Method: Subjects in a previous 12 month randomized controlled trial of TPTD in RA were invited to receive 12 additional months of...

    journal_title:Scandinavian journal of rheumatology

    pub_type: 杂志文章

    doi:10.1080/03009742.2020.1772362

    authors: Duryea J,Gravallese EM,Wortman JR,Xu C,Lu B,Kay J,Solomon DH

    更新日期:2021-01-01 00:00:00

  • IgM, IgG and IgA rheumatoid factors (antiglobulins) in early rheumatoid arthritis and their production of articular index over one year.

    abstract::An enzyme-linked immunosorbent assay was used to detect antiglobulins (rheumatoid factors, RF) of various classes in 33 patients with recently diagnosed rheumatoid arthritis and to follow their progress with 3-monthly checks for 1 year. For RF, IgA-RF and IgM-RF showed greater sensitivity than the latex test, either o...

    journal_title:Scandinavian journal of rheumatology

    pub_type: 杂志文章

    doi:10.3109/03009748709165411

    authors: March RE,Kirwan JR,Reeback JS,Holborow EJ

    更新日期:1987-01-01 00:00:00

  • A radiological survey of the hips and knees in female specialist teachers of physical education.

    abstract::A radiological study of osteoarthrosis of the hips and knees has been performed in 364 female specialist physical education teachers, aged 46--60 years, who qualified between the years 1935 and 1950. The teachers were contacted by postal questionnaire and A.P. radiographs of the pelvis and knees were performed at a ho...

    journal_title:Scandinavian journal of rheumatology

    pub_type: 杂志文章

    doi:10.3109/03009747909114633

    authors: Eastmond CJ,Hudson A,Wright V

    更新日期:1979-01-01 00:00:00

  • Gammalinolenic acid treatment of fatigue associated with primary Sjögren's syndrome.

    abstract:OBJECTIVE:To evaluate the efficacy of the essential omega-6 fatty acid Gammalinolenic acid (GLA) on fatigue associated with primary Sjögren's syndrome. METHODS:Ninety patients with primary Sjögren's syndrome (with or without signs of autoimmunity) entered a 6-month double blind placebo-controlled randomised trial with...

    journal_title:Scandinavian journal of rheumatology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1080/03009740252937577

    authors: Theander E,Horrobin DF,Jacobsson LT,Manthorpe R

    更新日期:2002-01-01 00:00:00

  • Effects of osmium tetroxide on the rabbit knee joint normal synovial membrane.

    abstract::The effect of osmium tetroxide, which is used in treatment of rheumatoid arthritis, was histologically and electronmicroscopically examined in the normal synovial membrane of the rabbit. The animals were albino rabbits, and they were 20 altogether. 0.3 ml. of 1% OsO(4) solution was injected, i.a., in the right knee. T...

    journal_title:Scandinavian journal of rheumatology

    pub_type: 杂志文章

    doi:10.3109/03009747009165362

    authors: Möttönen M,Pantio M,Nevalainen T

    更新日期:1987-01-01 00:00:00

  • The prevalence of rheumatoid arthritis in different geographical areas in sweden.

    abstract::In the general population of 39,418 persons within areas in the counties of Norrbotten (BD), Jämtland (Z), Skaraborg (R), Kristianstad west coast (LV), and Kristianstad east coast (L) in Sweden all the inhabitants over the age of seven (in Norrbotten over the age of 14) were investigated for the total number of cases ...

    journal_title:Scandinavian journal of rheumatology

    pub_type: 杂志文章

    doi:10.3109/03009747009165382

    authors: Hellgren L

    更新日期:1987-01-01 00:00:00

  • Faecal blood loss during administration of acetylsalicylic acid, ketoprofen and two new ketoprofen sustained-release compounds.

    abstract::The influence of one week's treatment with acetylsalicylic acid, ketoprofen, ketoprofen sustained-release capsules (Biovail capsules), and ketoprofen sustained-release tablets (IBP tablet) on gastrointestinal bleeding was investigated in 41 healthy male volunteers by means of a radiochromium assay. The physiological f...

    journal_title:Scandinavian journal of rheumatology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.3109/03009748309098550

    authors: Ranløv PJ,Nielsen SP,Bärenholdt O

    更新日期:1983-01-01 00:00:00

  • Prevalence of interstitial lung involvement in patients with connective tissue diseases assessed with high-resolution computed tomography.

    abstract:OBJECTIVES:To assess the prevalence of interstitial lung disease (ILD) in patients with different forms of connective tissue disease (CTD) using non-invasive procedures including high-resolution computed tomography (HRCT) and to evaluate the relationship between the imaging and functional status of the patients. METHO...

    journal_title:Scandinavian journal of rheumatology

    pub_type: 临床试验,杂志文章

    doi:10.1080/03009740600844381

    authors: Afeltra A,Zennaro D,Garzia P,Gigante A,Vadacca M,Ruggiero A,Dardes N,Navajas MF,Zobel BB,Amoroso A

    更新日期:2006-09-01 00:00:00

  • Increased prevalence of anti-thyroid antibodies in patients with limited scleroderma.

    abstract:OBJECTIVES:Thyroid dysfunction in the setting of systemic sclerosis (SSc) has been described previously. We aimed to determine the prevalence of anti-thyroid antibodies (ATA) in a large SSc cohort and to ascertain whether they are associated with distinct clinical phenotypes. METHODS:A total of 138 patients with SSc [...

    journal_title:Scandinavian journal of rheumatology

    pub_type: 杂志文章

    doi:10.3109/03009742.2010.549837

    authors: Danielides S,Mavragani CP,Katsakoulas I,Zintzaras E,Drosos AA,Vlachoyiannopoulos PG,Moutsopoulos HM

    更新日期:2011-01-01 00:00:00

  • Therapeutic effect of methotrexate encapsulated in cationic liposomes (EndoMTX) in comparison to free methotrexate in an antigen-induced arthritis study in vivo.

    abstract:OBJECTIVES:Cationic lipid complexes bind to angiogenic endothelial cells of solid tumours and microvessels of chronic inflammatory tissue. Methotrexate (MTX) is one of the drugs used in the therapy of rheumatoid arthritis (RA); it is applied systemically but can have serious side-effects. The aim of this study was to i...

    journal_title:Scandinavian journal of rheumatology

    pub_type: 杂志文章

    doi:10.3109/03009742.2015.1030448

    authors: Gottschalk O,Metz P,Dao Trong ML,Altenberger S,Jansson V,Mutschler W,Schmitt-Sody M

    更新日期:2015-01-01 00:00:00