The influence of antirheumatic drugs on the occurrence of peptic ulcers. A controlled study of patients with chronic rheumatic diseases.

Abstract:

:46 patients who had an ulcer (verified by X-ray pictures) during treatment at the Rheumatism Foundation Hospital were compared with two patient groups of the same size. The first control group consisted of randomly selected patients who had been examined in the same way for the same indications but where the X-ray pictures did not show any ulcer. The subjects in the second control group were of the same age and sex as the ulcer patients; this control group did not undergo any X-ray examination and had no history of ulcer. The study revealed that although most rheumatic patients were women (as in the first control group) there were significantly more men among the ulcer patients. The use of rapidly dissolving acetylsalicylic acid tablets was more common in the ulcer group; correspondingly the slowly absorbed tablets were used significantly more often by the controls. The risk of ulcer was also increased by the simultaneous use of several anti-inflammatory analgesics and/or corticosteroids.

journal_name

Scand J Rheumatol

authors

Martio J

doi

10.1080/03009748009098130

subject

Has Abstract

pub_date

1980-01-01 00:00:00

pages

55-9

issue

1

eissn

0300-9742

issn

1502-7732

journal_volume

9

pub_type

临床试验,杂志文章
  • Nailfold capillary permeability in psoriatic arthritis.

    abstract::This study is the first report of the permeability status of nailfold capillaries in psoriatic arthritis (PA). "Traditional" nailfold capillary microscopy and intravital fluorescence videomicroscopy were carried out at the nailfold of 13 patients with PA. Twenty five healthy subjects served as controls for nailfold ca...

    journal_title:Scandinavian journal of rheumatology

    pub_type: 杂志文章

    doi:10.3109/03009749209099229

    authors: Grassi W,Core P,Carlino G,Cervini C

    更新日期:1992-01-01 00:00:00

  • Differentiation between psoriatic arthritis and rheumatoid arthritis: a biochemical and statistical analysis of fingernail amino acids.

    abstract::The differentiation between psoriatic arthritis and rheumatoid arthritis can be clinically difficult if there is no manifest psoriasis of skin or nail. In order to clarify this diagnostic problem, the amino acid patterns in seventy-five psoriatic and non-psoriatic nails have been studied. Using gas--liquid chromatogra...

    journal_title:Scandinavian journal of rheumatology

    pub_type: 杂志文章

    doi:

    authors: Greaves MS,Fieller NR,Moll JM

    更新日期:1979-01-01 00:00:00

  • Sjögren's syndrome in inflammatory rheumatic diseases: analysis of the leukocyte protein calprotectin in plasma and saliva.

    abstract::In a hospital population of 154 patients with a wide range of inflammatory rheumatic diseases, patients with sicca symptoms were subjected to objective ocular and oral tests to establish cases with Sjögren's syndrome (SS). The plasma level of the leukocyte protein calprotectin has been shown to be a good indicator of ...

    journal_title:Scandinavian journal of rheumatology

    pub_type: 杂志文章

    doi:10.3109/03009749409103041

    authors: Brun JG,Cuida M,Jacobsen H,Kloster R,Johannesen AC,Høyeraal HM,Jonsson R

    更新日期:1994-01-01 00:00:00

  • Evaluation of choroidal substructure perfusion in patients affected by systemic sclerosis: an optical coherence tomography angiography study.

    abstract::Objective: Vasculopathy in systemic sclerosis (SSc) is characterized by the obliteration of arterioles and a reduced capillary density in various tissues. In SSc, atrophic alterations of the choroid have been suggested based on morphological data acquired by optical coherence tomography (OCT). In this study, we aimed ...

    journal_title:Scandinavian journal of rheumatology

    pub_type: 杂志文章

    doi:10.1080/03009742.2019.1641616

    authors: Ranjbar M,Rothe M,Klapa S,Lange T,Prasuhn M,Grisanti S,Riemekasten G,Humrich JY

    更新日期:2020-03-01 00:00:00

  • Effects of osmium tetroxide on the rabbit knee joint normal synovial membrane.

    abstract::The effect of osmium tetroxide, which is used in treatment of rheumatoid arthritis, was histologically and electronmicroscopically examined in the normal synovial membrane of the rabbit. The animals were albino rabbits, and they were 20 altogether. 0.3 ml. of 1% OsO(4) solution was injected, i.a., in the right knee. T...

    journal_title:Scandinavian journal of rheumatology

    pub_type: 杂志文章

    doi:10.3109/03009747009165362

    authors: Möttönen M,Pantio M,Nevalainen T

    更新日期:1987-01-01 00:00:00

  • More evidence of distinctive features of mixed connective tissue disease.

    abstract::A comparison of clinical, immunological and HLA-D region antigen features was made between 22 patients with mixed connective tissue disease (MCTD) and 118 patients with systemic lupus erythematosus (SLE), scleroderma or primary Sjögren's syndrome. The MCTD patients had hypergammaglobulinemia more often than did those ...

    journal_title:Scandinavian journal of rheumatology

    pub_type: 杂志文章

    doi:10.3109/03009749309095117

    authors: Hämeenkorpi R,Ruuska P,Forsberg S,Tiilikainen R,Mäkitalo R,Hakala M

    更新日期:1993-01-01 00:00:00

  • Clinical features of axial undifferentiated spondyloarthritis (USpA) in China: HLA-B27 is more useful for classification than MRI of the sacroiliac joint.

    abstract:OBJECTIVES:To analyse the clinical features of Chinese undifferentiated spondyloarthritis (USpA) patients with predominantly axial involvement, and in particular the influence of human leucocyte antigen (HLA)-B27 and magnetic resonance imaging (MRI) of the sacroiliac joint (SIJ) on the classification of axial USpA. ME...

    journal_title:Scandinavian journal of rheumatology

    pub_type: 杂志文章

    doi:10.3109/03009742.2011.585348

    authors: Liao Z,Lin Z,Xu M,Hu Z,Li T,Wei Q,Cao S,Huang J,Pan Y,Wu Y,Gu J

    更新日期:2011-11-01 00:00:00

  • Cyclic nucleotides and catecholamines in rheumatoid arthritis.

    abstract::A controlled cross over study on the effect of fasting on cyclic nucleotide and catecholamine excretion was carried out in 12 female RA patients. They were hospitalized during a control and fasting period. The fasting period started with 3 days of habituation to hospital conditions, followed by 7 days of total fasting...

    journal_title:Scandinavian journal of rheumatology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.3109/03009748309102906

    authors: Trang LE,Lövgren O,Norlund AE,Horn R,Walaas O

    更新日期:1983-01-01 00:00:00

  • Osteitis condensans ilii or sacro-iliitis?

    abstract::Eight patients with a radiological diagnosis of Osteitis condensans ilii (OCI) had clinical features similar to those of 8 patients with sacro-iliitis (SI). The X-ray appearances may be very difficult to differentiate on standard films and discrimination between the two conditions has to be made from a combination of ...

    journal_title:Scandinavian journal of rheumatology

    pub_type: 杂志文章

    doi:10.3109/03009748509165498

    authors: Withrington RH,Sturge RA,Mitchell N

    更新日期:1985-01-01 00:00:00

  • Involvement of the lateral atlanto-axial joints as first and late symptom of rheumatoid arthritis.

    abstract::Thirty cases of unilateral or bilateral atlanto-axial arthritis are described. They were found among 606 RA patients. According to the degree of involvement, the 30 cases were divided into four groups: A. 16 cases. B. 5 cases. C. 7 cases. D. 2 cases. In two patients the atlanto-axial arthritis was the primary lesion. ...

    journal_title:Scandinavian journal of rheumatology

    pub_type: 杂志文章

    doi:10.3109/03009747009165372

    authors: Kerckhove HV

    更新日期:1987-01-01 00:00:00

  • Collagenase synthesis of rheumatoid arthritis synoviocytes: dose-dependent stimulation by substance P and capsaicin.

    abstract::The synthesis and release of collagenase in the presence of the neuropeptide substance P (SP) and capsaicin, were investigated in vitro using identical synoviocyte cultures from patients with rheumatoid arthritis (RA). On average 10(-12) M SP augmented statistically significantly the collagenase production by approxim...

    journal_title:Scandinavian journal of rheumatology

    pub_type: 杂志文章

    doi:10.3109/03009749109165283

    authors: Partsch G,Matucci-Cerinic M,Marabini S,Jantsch S,Pignone A,Cagnoni M

    更新日期:1991-01-01 00:00:00

  • Work ability of Dutch employees with rheumatoid arthritis.

    abstract:OBJECTIVES:To (i) examine the association between fatigue, psychosocial work characteristics (job control, support, participation in decision making, psychological job demands), and physical work requirements on the one hand and work ability of employees with rheumatoid arthritis (RA) on the other, and (ii) determine t...

    journal_title:Scandinavian journal of rheumatology

    pub_type: 杂志文章

    doi:10.1080/03009740510018615

    authors: de Croon EM,Sluiter JK,Nijssen TF,Kammeijer M,Dijkmans BA,Lankhorst GJ,Frings-Dresen MH

    更新日期:2005-07-01 00:00:00

  • Body mass does not affect the remission of psoriatic arthritis patients on anti-TNF-α therapy.

    abstract:OBJECTIVES:There is evidence that fat tissue may influence the response to therapy in patients with arthritis. The aim of this study was to assess whether the body mass index (BMI) affects rates of clinical remission in patients with psoriatic arthritis (PsA) treated with anti-tumour necrosis factor (TNF)-α biological ...

    journal_title:Scandinavian journal of rheumatology

    pub_type: 杂志文章

    doi:10.3109/03009742.2012.715186

    authors: Iannone F,Fanizzi R,Scioscia C,Anelli MG,Lapadula G

    更新日期:2013-01-01 00:00:00

  • Symptomatology and diagnosis in connective tissue disease. II. Evaluations and follow-up examinations in consequence of a speckled antinuclear immunofluorescence pattern.

    abstract::Antibodies to soluble ribonucleoprotein (sRNP) are by definition a prerequisite for the diagnosis mixed connective tissue disease (MCTD). They are also found in 30--40% of other rheumatic conditions with a high titred speckled IFL reaction. The same is true for the most characteristic clinical features of MCTD, viz. R...

    journal_title:Scandinavian journal of rheumatology

    pub_type: 杂志文章

    doi:10.3109/03009747809095661

    authors: Jonsson J,Norberg R

    更新日期:1978-01-01 00:00:00

  • Rasch analysis of the Norwegian version of the Arthritis Self-Efficacy Scale (ASES).

    abstract:OBJECTIVES:To apply the Rasch model to the Norwegian version of the Arthritis Self-Efficacy Scale (ASES). METHOD:The ASES was included in a self-administered questionnaire sent to 224 patients attending one of three rehabilitation centres for rheumatic diseases in Norway in 2009. The fit of the ASES to the Rasch model...

    journal_title:Scandinavian journal of rheumatology

    pub_type: 杂志文章

    doi:10.3109/03009742.2016.1155644

    authors: Garratt AM,Klokkerud M,Løchting I,Hagen KB

    更新日期:2017-01-01 00:00:00

  • Anti-inflammatory effect of dialysable leucocyte extract in a rat model of osteoarthritis: histopathological and molecular characterization.

    abstract:OBJECTIVES:To evaluate the effect of dialysable leucocyte extract (DLE) on pro- and anti-inflammatory profiles in a rat model of osteoarthritis (OA). METHOD:Forty-eight male Wistar rats were divided into three groups: normal rats without treatment, OA rats treated with placebo, and OA rats treated with DLE. After trea...

    journal_title:Scandinavian journal of rheumatology

    pub_type: 杂志文章

    doi:10.3109/03009742.2016.1153140

    authors: Acosta P,Pérez N,Pérez E,Correa B,Pérez C,Gómez C,Sánchez V,Pérez DG

    更新日期:2016-11-01 00:00:00

  • Magnetic resonance imaging of the femoral head to detect avascular necrosis in active rheumatoid arthritis treated with methylprednisolone pulse therapy.

    abstract::Efficacious management of patients with avascular necrosis of bone (AVN) necessitates the identification of patients with a high risk of collapse of the femoral head. In this prospective study we imaged both hips of 10 patients with active rheumatoid arthritis, who were treated with methylprednisolone pulse therapy. M...

    journal_title:Scandinavian journal of rheumatology

    pub_type: 杂志文章

    doi:10.3109/03009749609069211

    authors: van Vugt RM,Sijbrandij ES,Bijlsma JW

    更新日期:1996-01-01 00:00:00

  • Cytokine production (IL-6 and TNF alpha) in whole blood cell cultures of patients with systemic lupus erythematosus.

    abstract::Whole blood cell culture has great advantage over isolated peripheral blood mononuclear cell culture, because it needs only small amounts of blood and is fast to perform. The current report focuses on the measurement of IL-6 and TNF alpha produced by peripheral blood monocytes of patients with systemic lupus erythemat...

    journal_title:Scandinavian journal of rheumatology

    pub_type: 杂志文章

    doi:10.3109/03009749609069992

    authors: Swaak AJ,van den Brink HG,Aarden LA

    更新日期:1996-01-01 00:00:00

  • IgM, IgG and IgA rheumatoid factors (antiglobulins) in early rheumatoid arthritis and their production of articular index over one year.

    abstract::An enzyme-linked immunosorbent assay was used to detect antiglobulins (rheumatoid factors, RF) of various classes in 33 patients with recently diagnosed rheumatoid arthritis and to follow their progress with 3-monthly checks for 1 year. For RF, IgA-RF and IgM-RF showed greater sensitivity than the latex test, either o...

    journal_title:Scandinavian journal of rheumatology

    pub_type: 杂志文章

    doi:10.3109/03009748709165411

    authors: March RE,Kirwan JR,Reeback JS,Holborow EJ

    更新日期:1987-01-01 00:00:00

  • Cystatin C concentration is correlated with disease activity in rheumatoid arthritis patients.

    abstract:OBJECTIVES:Rheumatoid arthritis (RA) is a systemic, inflammatory disease. Renal involvement worsens the course of RA and increases mortality. It is suggested that chronic inflammatory processes may contribute to renal impairment. The aim of this study was to investigate the impact of chronic inflammation and RA activit...

    journal_title:Scandinavian journal of rheumatology

    pub_type: 杂志文章

    doi:10.3109/03009742.2011.571219

    authors: Targońska-Stepniak B,Majdan M

    更新日期:2011-01-01 00:00:00

  • Atlanto-axial subluxation in rheumatoid arthritis. A study of 104 hospital patients.

    abstract::Arthritic affection of the upper cervical spine is relatively common in rheumatoid arthritis (RA). Atlanto-axial subluxations are also reported to occur frequently, but it seems that neurological symptoms due to the subluxations seldom occur. We have studied 104 consecutive in-patients. In a group of 50 non-arthritics...

    journal_title:Scandinavian journal of rheumatology

    pub_type: 杂志文章

    doi:10.3109/03009748409111302

    authors: Haaland K,Aadland HA,Haavik TK,Vallersnes FM

    更新日期:1984-01-01 00:00:00

  • Ileocolonoscopic and histologic studies of Korean patients with ankylosing spondylitis.

    abstract::We investigated the frequency of gut inflammation and the role of gut lesion in the pathogenesis of the ankylosing spondylitis (AS) in Korean patients. Ileocolonoscopy and biopsy of the colon and terminal ileum were performed on 24 Korean patients with AS. Endoscopic lesions were observed in 7 patients (29.2%). The le...

    journal_title:Scandinavian journal of rheumatology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.3109/03009749709065722

    authors: Lee YH,Ji JD,Kim JS,Bak YT,Lee CH,Kim CH,Chae YS,Song GG

    更新日期:1997-01-01 00:00:00

  • In vivo interactions of platelets and leucocytes with the endothelium in murine antigen-induced arthritis: the role of P-selectin.

    abstract:OBJECTIVE:Platelets are thought to participate in the pathogenesis of chronic inflammatory diseases such as rheumatoid arthritis (RA). We showed recently an in vivo increase in platelet-endothelial cell interactions in mice with antigen-induced arthritis (AiA). The underlying mechanisms are not yet clear. The aim of th...

    journal_title:Scandinavian journal of rheumatology

    pub_type: 杂志文章

    doi:10.1080/03009740701218741

    authors: Schmitt-Sody M,Metz P,Klose A,Gottschalk O,Zysk S,Hausdorf J,Veihelmann A,Jansson V

    更新日期:2007-07-01 00:00:00

  • Prevalence and predictors of vitamin D deficiency in non-supplemented women with systemic lupus erythematosus in the Mediterranean region: a cohort study.

    abstract:OBJECTIVES:Over the past few years researchers have suggested that vitamin D plays a diverse role in autoimmune diseases such as systemic lupus erythematosus (SLE). We sought to determine the prevalence and predictors of vitamin D deficiency in a cohort of non-supplemented female SLE patients from the Mediterranean reg...

    journal_title:Scandinavian journal of rheumatology

    pub_type: 杂志文章

    doi:10.3109/03009742.2012.697189

    authors: Muñoz-Ortego J,Torrente-Segarra V,Prieto-Alhambra D,Salman-Monte TC,Carbonell-Abello J

    更新日期:2012-01-01 00:00:00

  • Orofacial pain and dysfunction in children with juvenile idiopathic arthritis: a case-control study.

    abstract:OBJECTIVES:Juvenile idiopathic arthritis (JIA) frequently causes temporomandibular joint (TMJ) inflammation. The aim of this study was to evaluate the presence of orofacial pain and temporomandibular dysfunction in patients with JIA and controls. METHODS. Forty-one patients with JIA and 41 age- and sex-matched healthy ...

    journal_title:Scandinavian journal of rheumatology

    pub_type: 杂志文章

    doi:10.3109/03009742.2012.675585

    authors: Leksell E,Ernberg M,Magnusson B,Hedenberg-Magnusson B

    更新日期:2012-10-01 00:00:00

  • Radiographic assessment in relation to clinical and biochemical variables in rheumatoid arthritis.

    abstract::Radiographs of hands and feet were obtained from 125 consecutive patients with rheumatoid arthritis (RA) and the degree of destruction was assessed numerically on a 200-point scale using Larsen's standard radiographs as reference. The method is shown to possess a satisfactory degree of reproducibility. In 96 of these ...

    journal_title:Scandinavian journal of rheumatology

    pub_type: 杂志文章

    doi:10.3109/03009748809098805

    authors: Wollheim FA,Pettersson H,Saxne T,Sjöblom KG

    更新日期:1988-01-01 00:00:00

  • X-ray diffraction analysis of spontaneously draining calcinosis in scleroderma patients.

    abstract:OBJECTIVES:Calcium hydroxyapatite (HA) is reported to be the major constituent of soft tissue calcinosis in patients with scleroderma (systemic sclerosis, SSc). Mechanical stress and local tissue hypoxia are thought to be important in the pathogenesis of SSc calcinosis. We sought to analyse spontaneously draining mater...

    journal_title:Scandinavian journal of rheumatology

    pub_type: 杂志文章

    doi:10.1080/03009742.2016.1219766

    authors: Hsu VM,Emge T,Schlesinger N

    更新日期:2017-03-01 00:00:00

  • Wrist synovectomy in juvenile chronic arthritis (JCA).

    abstract::Synovectomy of 20 wrist joints in 15 patients with juvenile chronic arthritis (JCA) was performed and results were evaluated 3 (0.5-5) years after surgery. The surgical procedure consisted of synovectomy of the radiocarpal joint, around the ulnar head and in all intercarpal joints. Resection of the ulnar head was not ...

    journal_title:Scandinavian journal of rheumatology

    pub_type: 杂志文章

    doi:10.3109/03009749009102534

    authors: Hanff G,Sollerman C,Elborgh R,Pettersson H

    更新日期:1990-01-01 00:00:00

  • Detection of cytokine mRNA in human, articular cartilage from patients with rheumatoid arthritis and osteoarthritis by reverse transcriptase-polymerase chain reaction.

    abstract::Cytokines are signalling glycoproteins mediating acute inflammation, chronic inflammation, and connective tissue destruction. The present study was designed to characterize the profile of cytokine message in normal human articular cartilage and from patients with rheumatoid arthritis (RA) and osteoarthritis (OA), by m...

    journal_title:Scandinavian journal of rheumatology

    pub_type: 杂志文章

    doi:10.1080/030097498441191

    authors: Leistad L,Ostensen M,Faxvaag A

    更新日期:1998-01-01 00:00:00

  • Large vessel involvement in biopsy-proven giant cell arteritis: incidence, distribution, and predictors.

    abstract:OBJECTIVES:Giant cell arteritis (GCA) is a systemic disease with extensive vascular involvement. The aim of this study was to investigate the cumulative incidence of large vessel involvement (LVI) in GCA, the distribution of vessels involved, and predictors for LVI. METHOD:Patients with biopsy-proven GCA in a defined ...

    journal_title:Scandinavian journal of rheumatology

    pub_type: 杂志文章

    doi:10.1080/03009742.2016.1190984

    authors: Naderi N,Mohammad AJ,Turesson C

    更新日期:2017-05-01 00:00:00