Serum levels of soluble interleukin-2 receptor in patients with systemic lupus erythematosus and systemic idiopathic vasculitis.

abstract：OBJECTIVE:To determine the impact of a broad spectrum of different polymorphisms within the interleukin-10 (IL-10) promoter gene on disease susceptibility to primary Sjogren's syndrome (pSS), clinical manifestations, and autoantibody production. METHODS:We genotyped 111 unrelated German Caucasian patients with pSS and...

journal_title：Scandinavian journal of rheumatology

authors： Willeke P,Gaubitz M,Schotte H,Becker H,Domschke W,Schlüter B

更新日期：2008-07-01 00:00:00

abstract：OBJECTIVES:Juvenile idiopathic arthritis (JIA) frequently causes temporomandibular joint (TMJ) inflammation. The aim of this study was to evaluate the presence of orofacial pain and temporomandibular dysfunction in patients with JIA and controls. METHODS. Forty-one patients with JIA and 41 age- and sex-matched healthy ...

journal_title：Scandinavian journal of rheumatology

authors： Leksell E,Ernberg M,Magnusson B,Hedenberg-Magnusson B

更新日期：2012-10-01 00:00:00

abstract：:Synovectomy of 20 wrist joints in 15 patients with juvenile chronic arthritis (JCA) was performed and results were evaluated 3 (0.5-5) years after surgery. The surgical procedure consisted of synovectomy of the radiocarpal joint, around the ulnar head and in all intercarpal joints. Resection of the ulnar head was not ...

journal_title：Scandinavian journal of rheumatology

authors： Hanff G,Sollerman C,Elborgh R,Pettersson H

更新日期：1990-01-01 00:00:00

abstract：:Objective: Vasculopathy in systemic sclerosis (SSc) is characterized by the obliteration of arterioles and a reduced capillary density in various tissues. In SSc, atrophic alterations of the choroid have been suggested based on morphological data acquired by optical coherence tomography (OCT). In this study, we aimed ...

journal_title：Scandinavian journal of rheumatology

authors： Ranjbar M,Rothe M,Klapa S,Lange T,Prasuhn M,Grisanti S,Riemekasten G,Humrich JY

更新日期：2020-03-01 00:00:00

abstract：OBJECTIVE:We sought to determine whether the serological response towards lytic cycle antigens of Epstein-Barr virus (EBV) is altered in systemic lupus erythematosus (SLE) patients. METHOD:We used enzyme-linked immunosorbent assay (ELISA) to investigate the prevalence of EBV early antigen diffuse (EBV-EA/D) antibodies...

journal_title：Scandinavian journal of rheumatology

authors： Draborg AH,Jørgensen JM,Müller H,Nielsen CT,Jacobsen S,Iversen LV,Theander E,Nielsen LP,Houen G,Duus K

更新日期：2012-08-01 00:00:00

abstract：:Rituximab is a genetically engineered chimeric monoclonal immunoglobulin (Ig)G1 antibody. It binds the CD20 trans-membrane surface antigen expressed by mature B cells but not by antibody secreting plasma cells, and removes the cells by activating complement, inducing cell-mediated lysis, and by apoptosis. Mainly used ...

journal_title：Scandinavian journal of rheumatology

authors： Omdal R,Wildhagen K,Hansen T,Gunnarsson R,Kristoffersen G

更新日期：2005-05-01 00:00:00

abstract：:An impairment of the renal function was observed in three patients who received azapropazone for various rheumatic disorders with simultaneous hyperuricaemia. A distinct increase in serum creatinine occurred in all patients. In one case the renal biopsy suggested a hypersensitivity reaction with a consequent acute tub...

journal_title：Scandinavian journal of rheumatology

authors： Sipilä R,Skrifvars B,Törnroth T

更新日期：1986-01-01 00:00:00

abstract：:Objectives: To study associations between different anthropometric measures and incident gout, and to find the best predictive measure. Method: We used the baseline investigation from the Malmö Diet and Cancer study, excluding cases of prevalent gout (n = 28 081). Cox regression for each anthropometric measurement was...

journal_title：Scandinavian journal of rheumatology

authors： Wändell P,Andreasson A,Hagström H,Kapetanovic MC,Carlsson AC

更新日期：2019-07-01 00:00:00

abstract：:Antibodies to soluble ribonucleoprotein (sRNP) are by definition a prerequisite for the diagnosis mixed connective tissue disease (MCTD). They are also found in 30--40% of other rheumatic conditions with a high titred speckled IFL reaction. The same is true for the most characteristic clinical features of MCTD, viz. R...

journal_title：Scandinavian journal of rheumatology

authors： Jonsson J,Norberg R

更新日期：1978-01-01 00:00:00

abstract：:Objective: Low molecular mass hyaluronan causes inflammatory processes and can act as a pro-inflammatory cytokine in skin and other sites of activity in psoriatic arthritis (PsA). This study investigated whether the molecular mass distribution of hyaluronan (HA) in skin and the quantity of circulating HA are related t...

journal_title：Scandinavian journal of rheumatology

authors： Hellman U,Engström-Laurent A,Larsson A,Lindqvist U

更新日期：2019-07-01 00:00:00

abstract：:Objectives: IgG4-related disease (IgG4-RD) may present as 'idiopathic' retroperitoneal fibrosis (IRPF). We aimed to determine the occurrence of IgG4-retroperitoneal fibrosis (IgG4-RPF) in a nationwide study on patients with newly diagnosed IRPF, and to compare histopathological, imaging, and clinical features in the I...

journal_title：Scandinavian journal of rheumatology

authors： Lomborg N,Jakobsen M,Bode CS,Junker P

更新日期：2019-07-01 00:00:00

abstract：OBJECTIVE:Interleukin-1 (IL-1) has been implicated in the pathogenesis of several rheumatic inflammatory diseases, including adult-onset Still's disease (AOSD) and systemic-onset juvenile idiopathic arthritis (SoJIA). Several clinical trials also suggest that anakinra, a human recombinant interleukin-1 receptor antagon...

journal_title：Scandinavian journal of rheumatology

authors： Youm JY,Woo JH,Kim TH,Bae SC,Yoo DH

更新日期：2007-09-01 00:00:00

abstract：OBJECTIVES:To assess whether subclinical inflammatory changes are present on magnetic resonance imaging (MRI) in patients with inflammatory bowel disease (IBD) and arthralgia. METHOD:In this pilot study, painful hand joints [metacarpophalangeal (MCP), proximal interphalangeal (PIP), and/or distal interphalangeal (DIP)...

journal_title：Scandinavian journal of rheumatology

authors： Brakenhoff LK,Stomp W,van Gaalen FA,Hommes DW,Bloem JL,van der Heijde DM,Fidder HH,Reijnierse M

更新日期：2014-01-01 00:00:00

abstract：:The lupus anticoagulant (LAC) is associated with the occurrence of thromboembolic complications. Assuming that thrombosis may underlie manifestations of the central nervous system (CNS) in patients with systemic lupus erythematosus (SLE), we studied 20 patients with SLE and CNS manifestations for the presence of LAC. ...

journal_title：Scandinavian journal of rheumatology

authors： Derksen RH,Bouma BN,Kater L

更新日期：1986-01-01 00:00:00

abstract：:This population study includes the majority of all systemic lupus erythematosus (SLE) patients in Iceland (n = 65). The study lists various self-rated pain descriptions both from a 54-item pain questionnaire and from the somatisation section of the Diagnostic Interview Schedule (DIS). Results show SLE patients to have...

journal_title：Scandinavian journal of rheumatology

authors： Líndal E,Thorlacius S,Stefánsson JG,Steinsson K

更新日期：1993-01-01 00:00:00

abstract：OBJECTIVE:To evaluate the influence of geographic variation on the risk of digital ulcer (DU) development in systemic sclerosis (SSc) patients. METHODS:This cross-sectional, multicentre study evaluated patients with SSc from centres located in different geographic regions of Brazil (subtropical and tropical climate zo...

journal_title：Scandinavian journal of rheumatology

authors： Souza E,Muller CS,Horimoto A,Rezende RA,Guimarães I,Mariz HA,Dantas AT,Da Costa IP,Del-Rio A,Sekiyama J,Kahwage CB,Kayser C

更新日期：2017-07-01 00:00:00

abstract：:Linné and Boissier de la Croix de Sauvages, two botanists and physicians of the mideighteenth century, proposed systems for the classification of diseases. Their medical works have been examined for passages suggestive of rheumatoid arthritis (RA). References to gouty arthritis dominated in Linné's works. Sauvages des...

journal_title：Scandinavian journal of rheumatology

authors： Hansen SE

更新日期：1993-01-01 00:00:00

abstract：:The changes in MR-determined synovial membrane volume, early synovial enhancement, and cartilage and bone erosions after osmic acid knee synovectomy were studied. Gadolinium-DTPA enhanced magnetic resonance imaging (MRI) of 18 knees with persistent arthritis was performed before and 1 month after treatment. The synovi...

journal_title：Scandinavian journal of rheumatology

authors： Ostergaard M,Stoltenberg M,Gideon P,Wieslander S,Sonne-Holm S,Kryger P,Sonne M

更新日期：1995-01-01 00:00:00

abstract：:A comparison of clinical, immunological and HLA-D region antigen features was made between 22 patients with mixed connective tissue disease (MCTD) and 118 patients with systemic lupus erythematosus (SLE), scleroderma or primary Sjögren's syndrome. The MCTD patients had hypergammaglobulinemia more often than did those ...

journal_title：Scandinavian journal of rheumatology

authors： Hämeenkorpi R,Ruuska P,Forsberg S,Tiilikainen R,Mäkitalo R,Hakala M

更新日期：1993-01-01 00:00:00

abstract：OBJECTIVE:To compare the impact on quality of life (QoL) of omeprazole and misoprostol during healing, and omeprazole, misoprostol, and placebo during maintenance treatment in chronic NSAID users with NSAID-associated gastroduodenal lesions. METHODS:Validated baseline and follow-up QoL questionnaires were completed by...

journal_title：Scandinavian journal of rheumatology

authors： Yeomans N,Wilson I,Långström G,Hawkey C,Naesdal J,Walan A,Wiklund I

更新日期：2001-01-01 00:00:00

abstract：:SA 96 (N-(2-mercapto-2-methylpropanoyl)-L-cysteine) is a new sulfhydryl compound having a relatively similar chemical structure to Tiopronin and D-penicillamine. An open trial of SA 96 treatment (300 mg/day after meals for 16 weeks) was carried out in 11 patients with definite or classical rheumatoid arthritis and wit...

journal_title：Scandinavian journal of rheumatology

authors： Ishikawa K,Sakaguchi M

更新日期：1986-01-01 00:00:00

abstract：OBJECTIVE:To study mortality from infections and accuracy of pre-mortem diagnoses in patients with rheumatoid arthritis (RA) autopsied during a 40-year period. METHODS:We investigated infectious causes of death, findings at autopsy, and clinicians' estimation of cause of death in 369 consecutively autopsied RA and 371...

journal_title：Scandinavian journal of rheumatology

authors： Koivuniemi R,Leirisalo-Repo M,Suomalainen R,Piirainen H,Paimela L

更新日期：2006-07-01 00:00:00

abstract：OBJECTIVES:Reactive arthritis (ReA) is a sterile joint inflammation triggered by a remote infection and associated with human leucocyte antigen (HLA)-B27. Its pathogenesis is unknown, but abnormal response to microbial structures or endogenous inflammatory mediators may be involved. We studied responses in leucocyte si...

journal_title：Scandinavian journal of rheumatology

authors： Alanärä T,Aittomäki S,Kuuliala K,Kuuliala A,Siitonen S,Leirisalo-Repo M,Repo H

更新日期：2012-08-01 00:00:00

abstract：OBJECTIVES:To determine the prevalence and predictors of influenza and influenza-like symptoms in patients with rheumatoid arthritis (RA). METHOD:Questionnaires were sent to patients registered as having RA and they were asked to fill in per month any period and details of influenza-like symptoms and vaccination. An e...

journal_title：Scandinavian journal of rheumatology

authors： Dirven L,Huizinga TW,Allaart CF

更新日期：2012-10-01 00:00:00

abstract：:Objective: Pain is a common and distressing feature of juvenile idiopathic arthritis (JIA). Pain interference (PI) is underexplored in long-term conditions such as JIA. The aim of this study was to explore the factors associated with PI in young adults with JIA. Methods: All consecutive JIA patients aged 18-30 years i...

journal_title：Scandinavian journal of rheumatology

authors： Rebane K,Orenius T,Ristolainen L,Relas H,Kautiainen H,Luosujärvi R,Säilä H,Aalto K

更新日期：2019-09-01 00:00:00

abstract：:Glucocorticoids (GCs) have powerful and potent anti-inflammatory and immunomodulatory effects in rheumatoid arthritis (RA) and many other diseases. These effects are mediated by up to four different mechanisms of action: cytosolic glucocorticoid receptor (cGCR)-mediated classical genomic and rapid non-genomic effects,...

journal_title：Scandinavian journal of rheumatology

authors： Buttgereit F,Saag KG,Cutolo M,da Silva JA,Bijlsma JW

更新日期：2005-01-01 00:00:00

abstract：:The initial evaluation of 25 patients suspected of suffering from Sjögren's syndrome (SS) disclosed that sialopenia and glandular atrophy without focal sialo-adenitis was the second most common cause, after SS itself, of patient complaints. This emphasizes the importance of conclusive diagnostic criteria to prevent ov...

journal_title：Scandinavian journal of rheumatology

authors： Malmström MJ,Segerberg-Konttinen M,Tuominen TS,Hietanen JH,Wolf JE,Sane JI,Konttinen YT

更新日期：1988-01-01 00:00:00

abstract：OBJECTIVE:We sought to investigate the cost of living with rheumatoid arthritis (RA) and evaluate the influence of both demographics and specific disease characteristics on these costs. METHODS:We used a population-based questionnaire to survey 895 patients living in the city of Malmö, Sweden, during 2002. Data were o...

journal_title：Scandinavian journal of rheumatology

authors： Jacobsson LT,Lindroth Y,Marsal L,Juran E,Bergström U,Kobelt G

更新日期：2007-05-01 00:00:00

abstract：:The aetiology of ankylosing spondylitis (AS) may involve certain enterobacteria. It is therefore interesting that serum polymeric IgA, a precursor of secretory IgA, was statistically elevated in active AS (n = 35) and that levels were comparable to those found in yersiniosis (n = 12); this might indicate antigenic sti...

journal_title：Scandinavian journal of rheumatology

authors： van Bohemen CG,Nabbe AJ,Goei The HS,Mazurkiewicz ES,van der Linden S,Zanen HC

更新日期：1986-01-01 00:00:00

abstract：OBJECTIVES:Patients with rheumatoid arthritis (RA) have a high risk of cardiovascular disease (CVD). Recent national and international guidelines suggest strict treatment of CVD risk factors in RA. The aim of this study was to evaluate the self-reported adherence to CV prevention strategies in patients with RA. METHOD...

journal_title：Scandinavian journal of rheumatology

authors： van Breukelen-van der Stoep DF,Zijlmans J,van Zeben D,Klop B,van de Geijn GJ,van der Meulen N,Hazes M,Birnie E,Castro Cabezas M

更新日期：2015-01-01 00:00:00