Abstract:
:Complement activation products, C9 and C3-containing circulating immune complexes (CIC), were evaluated in plasma and synovial fluid (SF) from patients with rheumatoid arthritis (RA) and osteoarthritis. C3 activation products and the fluid phase terminal complement complex were considerably elevated in SF from RA patients reaching levels five- to eighttimes that in plasma, consistant with a local activation of the whole cascade in the joints. The results emphazise the importance of detecting C3 activation by neoepitope expression instead of single fragment determinations. The concentration of native C9 was lower in synovial fluid compared with plasma, consistant with the excessive local complement activation. Increased CIC levels which correlated with the degree of complement activation were also found in the SF from the RA patients.
journal_name
Scand J Rheumatoljournal_title
Scandinavian journal of rheumatologyauthors
Olmez U,Garred P,Mollnes TE,Harboe M,Berntzen HB,Munthe Edoi
10.3109/03009749109103019subject
Has Abstractpub_date
1991-01-01 00:00:00pages
183-9issue
3eissn
0300-9742issn
1502-7732journal_volume
20pub_type
杂志文章abstract::Preliminary studies indicate that plasma zinc concentrations, as estimated by atomic absorption spectrophotometry, are reduced in rheumatoid arthritis. A relationship has also been established between metacarpal index of osteoporosis and plasma zinc concentrations in rheumatoid subjects. ...
journal_title:Scandinavian journal of rheumatology
pub_type: 杂志文章
doi:10.3109/03009747509165264
更新日期:1975-01-01 00:00:00
abstract:OBJECTIVE:To measure serum levels of antibodies against cyclic citrullinated peptide (anti-CCP antibodies) and serum cartilage oligomeric matrix protein (COMP) in patients with early joint inflammation, and to study the correlation of these two tests with clinical measurements. METHODS:Adult patients with recent-onset...
journal_title:Scandinavian journal of rheumatology
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doi:10.1080/03009740310004856
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abstract:OBJECTIVE:To evaluate the influence of geographic variation on the risk of digital ulcer (DU) development in systemic sclerosis (SSc) patients. METHODS:This cross-sectional, multicentre study evaluated patients with SSc from centres located in different geographic regions of Brazil (subtropical and tropical climate zo...
journal_title:Scandinavian journal of rheumatology
pub_type: 杂志文章,多中心研究
doi:10.1080/03009742.2016.1233994
更新日期:2017-07-01 00:00:00
abstract::Out of a total of 150 patients attending an out-patient clinic for anticoagulant therapy, 12 had disorders which normally would indicate a prolonged use of an antirheumatic drug. To 6 of these patients, naproxen (1/4 g twice daily) was given while anticoagulant treatment with phenprocoumon was continued in an unchange...
journal_title:Scandinavian journal of rheumatology
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doi:
更新日期:1979-01-01 00:00:00
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journal_title:Scandinavian journal of rheumatology
pub_type: 杂志文章
doi:10.3109/03009742.2013.879606
更新日期:2014-01-01 00:00:00
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journal_title:Scandinavian journal of rheumatology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.3109/03009749309099253
更新日期:1993-01-01 00:00:00
abstract::Duplicate platelet survival studies were carried out on 10 patients with SLE. At the time of the first study 5 of them (group I) were untreated and the remaining 5 (group II) were receiving corticosteroid (CS) therapy. The second study was performed while group I patients received CS and group II patients CS + azathio...
journal_title:Scandinavian journal of rheumatology
pub_type: 杂志文章
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更新日期:1981-01-01 00:00:00
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journal_title:Scandinavian journal of rheumatology
pub_type: 杂志文章
doi:10.3109/03009748809098756
更新日期:1988-01-01 00:00:00
abstract::To investigate whether the therapeutic effect of etidronate is affected by the time of ingestion we have retrospectively studied 110 osteoporotic patients. They had been taking etidronate according to the manufacturer's instructions for a mean duration of 2.6 years either on waking (n=47), on retiring (n=47), or durin...
journal_title:Scandinavian journal of rheumatology
pub_type: 杂志文章
doi:10.1080/030097400750001824
更新日期:2000-01-01 00:00:00
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journal_title:Scandinavian journal of rheumatology
pub_type: 杂志文章
doi:10.3109/03009748509102043
更新日期:1985-01-01 00:00:00
abstract::The aim of the present study was to relate postural control, as measured on a quantitative test battery as standing balance on an AMTI force platform, to results of muscle function of the lower extremities, aerobic capacity, disease characteristics, attitudes revealing anxiety, and demographic variables in patients wi...
journal_title:Scandinavian journal of rheumatology
pub_type: 杂志文章
doi:10.3109/03009749209099245
更新日期:1992-01-01 00:00:00
abstract::Efficacious management of patients with avascular necrosis of bone (AVN) necessitates the identification of patients with a high risk of collapse of the femoral head. In this prospective study we imaged both hips of 10 patients with active rheumatoid arthritis, who were treated with methylprednisolone pulse therapy. M...
journal_title:Scandinavian journal of rheumatology
pub_type: 杂志文章
doi:10.3109/03009749609069211
更新日期:1996-01-01 00:00:00
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journal_title:Scandinavian journal of rheumatology
pub_type: 杂志文章,随机对照试验
doi:10.1080/03009742.2018.1464206
更新日期:2019-01-01 00:00:00
abstract::Systemic lupus erythematosus (SLE) is an uncommon immunological disorder with multisystemic involvement. Neurological and neuropsychiatric manifestations in this disease are multifactorial and can involve any part of this system. We describe one patient presenting with spastic quadriparesis as an early clinical manife...
journal_title:Scandinavian journal of rheumatology
pub_type: 杂志文章
doi:10.1080/03009740310002579
更新日期:2003-01-01 00:00:00
abstract::Thirty-six patients with lateral epicondylitis of the elbow (19 women, 17 men, median age 48 yrs) were treated either with active laser or placebo, 18 patients in each group. The active laser was a GA-AL-AS 30 mW/830 nm low power laser (LPL). The study design was double blind and randomized. The treatment session cons...
journal_title:Scandinavian journal of rheumatology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.3109/03009749409103726
更新日期:1994-01-01 00:00:00
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journal_title:Scandinavian journal of rheumatology
pub_type: 杂志文章
doi:10.3109/03009748609102086
更新日期:1986-01-01 00:00:00
abstract:BACKGROUND:The study was done to determine whether the new SCORE (Simple Calculated Osteoporosis Risk Estimation) index might reduce the utilization of bone mineral density (BMD) measurement. METHODS:989 consecutive patients who were referred by a range of physicians for BMD assessments at one of two clinics had a SCO...
journal_title:Scandinavian journal of rheumatology
pub_type: 杂志文章
doi:10.1080/030097401750065300
更新日期:2001-01-01 00:00:00
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journal_title:Scandinavian journal of rheumatology
pub_type: 杂志文章
doi:10.3109/03009749209095055
更新日期:1992-01-01 00:00:00
abstract::To study the symptoms of NSAID-associated gastroduodenal bleeding, 94 patients (median age 71 years, range 19-90), were included in a prospective, clinical trial where hematemesis or melena from gastroduodenal ulceration or haemorrhagic/erosive gastritis were the inclusion criteria. NSAID use within one month was stud...
journal_title:Scandinavian journal of rheumatology
pub_type: 临床试验,杂志文章
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更新日期:1991-01-01 00:00:00
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journal_title:Scandinavian journal of rheumatology
pub_type: 杂志文章
doi:10.3109/03009748309102907
更新日期:1983-01-01 00:00:00
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journal_title:Scandinavian journal of rheumatology
pub_type: 杂志文章
doi:10.3109/03009748409100379
更新日期:1984-01-01 00:00:00
abstract::An investigation has been carried out on the presence of iron in striated muscle from normal individuals and from patients with rheumatoid disease. The methods used for the estimation of iron required a neutron activation analysis of total iron and extraction of hemoglobin in cyanide buffer. The results disclosed that...
journal_title:Scandinavian journal of rheumatology
pub_type: 杂志文章
doi:10.3109/03009747609099906
更新日期:1976-01-01 00:00:00
abstract::T cell receptor (V beta) use in the response to type II collagen and cartilage proteoglycans was analysed in peripheral blood and synovial fluid T cells from RA patients. T cells from RA patients with an immune response to connective tissue antigens, and paired PB and SF samples were stimulated in vitro with type II c...
journal_title:Scandinavian journal of rheumatology
pub_type: 杂志文章
doi:10.3109/03009749709065676
更新日期:1997-01-01 00:00:00
abstract::The differentiation between psoriatic arthritis and rheumatoid arthritis can be clinically difficult if there is no manifest psoriasis of skin or nail. In order to clarify this diagnostic problem, the amino acid patterns in seventy-five psoriatic and non-psoriatic nails have been studied. Using gas--liquid chromatogra...
journal_title:Scandinavian journal of rheumatology
pub_type: 杂志文章
doi:
更新日期:1979-01-01 00:00:00
abstract:OBJECTIVE:To evaluate the variability in the characteristics and management of rheumatoid arthritis (RA) patients between rheumatology attending physicians and training residents in Spain. METHODS:A retrospective medical record (MR) review was performed in a probabilistic sample of 1379 RA patients from 46 centres dis...
journal_title:Scandinavian journal of rheumatology
pub_type: 杂志文章,多中心研究
doi:10.1080/03009740802055992
更新日期:2008-11-01 00:00:00
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journal_title:Scandinavian journal of rheumatology
pub_type: 杂志文章
doi:10.3109/03009747909114633
更新日期:1979-01-01 00:00:00
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journal_title:Scandinavian journal of rheumatology
pub_type: 杂志文章
doi:10.1080/030097400750001978
更新日期:2000-01-01 00:00:00
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journal_title:Scandinavian journal of rheumatology
pub_type: 杂志文章
doi:10.3109/03009742.2012.680607
更新日期:2012-01-01 00:00:00
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journal_title:Scandinavian journal of rheumatology
pub_type: 杂志文章
doi:10.3109/03009741003685640
更新日期:2010-01-01 00:00:00
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journal_title:Scandinavian journal of rheumatology
pub_type: 杂志文章
doi:10.1080/03009742.2019.1602164
更新日期:2019-09-01 00:00:00