Infrasound-induced hemodynamics, ultrastructure, and molecular changes in the rat myocardium.

abstract：:2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) and polychlorinated biphenyls (PCBs) are persistent organic pollutants which coexist in environment, and human are co-exposed to these chemicals. Our present study was aimed to investigate the possible enhanced nonalcoholic fatty liver disease (NAFLD) in ApoE(-/-) mice co-exp...

journal_title：Environmental toxicology

authors： Shan Q,Huang F,Wang J,Du Y

更新日期：2015-12-01 00:00:00

abstract：:Manganese (Mn) plays a critical role in individual growth and development, yet excessive exposure can result in neurotoxicity, especially cognitive impairment. Neuronal apoptosis is considered as one of the mechanisms of Mn-induced neurotoxicity. Recent evidence suggests that cAMP-PKA-CREB signaling regulates apoptosi...

journal_title：Environmental toxicology

authors： Yang Y,Ma S,Wei F,Liang G,Yang X,Huang Y,Wang J,Zou Y

更新日期：2019-09-01 00:00:00

abstract：:Melanoma is the leading cause of death from skin disease due to its propensity for metastasis. Studies have shown that integrin-mediated focal adhesion kinase (FAK) signal pathway is implicated in cell proliferation, survival and metastasis of tumor cells. Our previous results indicated that diallyl trisulfide (DATS) ...

journal_title：Environmental toxicology

authors： Wang HC,Chu YL,Hsieh SC,Sheen LY

更新日期：2017-11-01 00:00:00

abstract：:In this study, toxic effects of the cypermethrin in Allium cepa L. cells were investigated. For this aim, we investigated the changes in pigment contents, antioxidant enzymes, mitotic index and chromosomal abnormalities as indicators of toxicity. The seeds were treated with different doses (1.5, 3.0, 6.0 ppm) of cyper...

journal_title：Environmental toxicology

authors： Çavuşoğlu K,Kaya A,Yilmaz F,Yalçin E

更新日期：2012-10-01 00:00:00

abstract：:Environmental stress factors may be responsible for biological changes in living species that are able to overcome deleterious effects depending on their detoxifying capacities. Defense systems present in every living species are involved in elimination of reactive chemical species of endogenous or exogenous origin, n...

journal_title：Environmental toxicology

authors： Vasseur P,Leguille C

更新日期：2004-08-01 00:00:00

abstract：:Adrenomedullin (AdM) is synthesized and secreted by a number of cells and tissue. AdM is a potent vasodilator but it is also considered a neuromodulator, an angiogenic factor, and a hormone regulator. AdM possess antiapoptotic, antioxidant, and antimicrobial properties. Heavy metals such as cadmium and lead are found ...

journal_title：Environmental toxicology

authors： Yurekli M,Esrefoglu M,Ilker Doğru M,Doğru A,Gul M,Whidden M

更新日期：2009-06-01 00:00:00

abstract：:Deguelin, a naturally occurring rotenoid of the flavonoid family, is known to be an Akt inhibitor, to have chemopreventive activities and anti-tumor effect on several cancers. In this study, investigation to elucidate the effect of deguelin on apoptotic pathways in human lung cancer cells and on the anti-tumor effect ...

journal_title：Environmental toxicology

authors： Hsu YC,Chiang JH,Yu CS,Hsia TC,Wu RS,Lien JC,Lai KC,Yu FS,Chung JG

更新日期：2017-01-01 00:00:00

abstract：:The aim of this study was to determine whether repeated exposure to iron oxide nanoparticles (Fe2 O3 -NPs) could be toxic to mice testis. Fe2 O3 -NPs (25 and 50 mg/kg) were intraperitoneally administered into mice once a week for 4 weeks. Our study showed that Fe2 O3 -NPs have the ability to cross the blood-testis bar...

journal_title：Environmental toxicology

authors： Sundarraj K,Manickam V,Raghunath A,Periyasamy M,Viswanathan MP,Perumal E

更新日期：2017-02-01 00:00:00

abstract：:Some species of the genera Anabaena can produce various kinds of cyanotoxins, which may pose risks to environment and human health. Anabaena has frequently been observed in eutrophic freshwater of China in recent years, but its toxicity has been reported only in a few studies. In the present study, the toxicity of an ...

journal_title：Environmental toxicology

authors： Pan X,Chang F,Liu Y,Li D,Xu A,Shen Y,Huang Z

更新日期：2009-02-01 00:00:00

abstract：:The aim of this study was to evaluate whether the enzyme-linked immunosorbent assay (ELISA) anti-Adda technique could be used to monitor free microcystins (MCs) in biological samples from fish naturally exposed to toxic cyanobacteria by using receiver operating characteristic (ROC) curve software to establish an optim...

journal_title：Environmental toxicology

authors： Moreno IM,Herrador MÁ,Atencio L,Puerto M,González AG,Cameán AM

更新日期：2011-02-01 00:00:00

abstract：:Arsenite has been shown to induce a variety of oxidative damage in mammalian cells. However, the mechanisms underlying cellular responses to its adverse effects remain unknown. We previously showed that the level of Nrf2, a nuclear transcription factor significantly increased in arsenite-treated human bronchial epithe...

journal_title：Environmental toxicology

authors： Chen C,Jiang X,Gu S,Lai Y,Liu Y,Zhang Z

更新日期：2017-08-01 00:00:00

abstract：:Contamination of the urban aquatic environment with chemical and biological substances could have a long-term impact on human health because these substances threaten the integrity of the urban ecosystem and the availability of high-quality water for recreation and consumption. In light of this, the aim of the present...

journal_title：Environmental toxicology

authors： Wichmann G,Daegelmann C,Herbarth O,Strauch G,Schirmer K,Wöstemeyer J,Lehmann I

更新日期：2004-12-01 00:00:00

abstract：:Intake of arsenic (As) via drinking water has been a serious threat to global public health. Though there are numerous reports of As neurotoxicity, its pathogenesis mechanisms remain vague especially its chronic effects on metabolic network. Hippocampus is a renowned area in relation to learning and memory, whilst rec...

journal_title：Environmental toxicology

authors： Mo TT,Dai H,Du H,Zhang RY,Chai KP,An Y,Chen JJ,Wang JK,Chen ZJ,Chen CZ,Jiang XJ,Tang R,Wang LP,Tan Q,Tang P,Miao XY,Meng P,Zhang LB,Cheng SQ,Peng B,Tu BJ,Han TL,Xia YY,Baker PN

更新日期：2019-02-01 00:00:00

abstract：:Being one of the notorious weed P. hysterophorus has invaded almost every part India and is the lead cause of skin allergies and severe dermatitis among farmers and rural population. It is an invasive obnoxious weed capable of surviving extreme environmental conditions and various parts of this plant are reported to c...

journal_title：Environmental toxicology

authors： Kaur M,Gupta KB,Thakur S,Kaur S,Dhiman M

更新日期：2020-11-01 00:00:00

abstract：:Acute toxicities of perfluorooctane sulfonate (PFOS) and perfluorooctanoic acid (PFOA) were tested on four freshwater species and three plant species. PFOS was more toxic than PFOA for all species tested in this study. Similar time-response patterns of PFOS and PFOA toxicity were observed for each tested species. Valu...

journal_title：Environmental toxicology

authors： Li MH

更新日期：2009-02-01 00:00:00

abstract：:Laboratory toxicity tests were performed to obtain more data on the toxicity of ammonia to saltwater organisms. The standards for in-stream ammonia limits in marine environments presently are based on toxicity tests involving both freshwater and saltwater organisms. Acute tests (48 and 96 h) were performed at 20 degre...

journal_title：Environmental toxicology

authors： Boardman GD,Starbuck SM,Hudgins DB,Li X,Kuhn DD

更新日期：2004-04-01 00:00:00

abstract：:In the present study, responses of the Chinese brown frog (Rana chensinensis) to exposure to di-2-ethylhexyl phthalate (DEHP), a common plasticizer, during the larval period were characterized. The effects of DEHP on metamorphosis rate, thyroid hormone, thyroid histology and the expression of genes involved in the ste...

journal_title：Environmental toxicology

authors： Zhang Y,Li X,Gao J,Wang H

更新日期：2018-01-01 00:00:00

abstract：:Lake Elphinstone is a tropical inland water body in the far north of the Fitzroy Catchment in Central Queensland, Australia, and has experienced recurrent toxic cyanoprokaryote blooms since 1997. This article reports on an examination of the environmental conditions of the lake and the concurrent cyanoprokaryote speci...

journal_title：Environmental toxicology

authors： White SH,Fabbro LD,Duivenvoorden LJ

更新日期：2003-12-01 00:00:00

abstract：:Micronucleus induction by the diarrhetic shellfish toxin okadaic acid (OA) was investigated in two intestinal models, cultured human Caco-2 cells and colon epithelial cells of mice treated in vivo. Exposure to OA for 4 and 24 h induced dose-responsive increases in the frequency of micronucleated Caco-2 cells; the mini...

journal_title：Environmental toxicology

authors： Le Hégarat L,Jacquin AG,Bazin E,Fessard V

更新日期：2006-02-01 00:00:00

abstract：:Chronic inhalation bioassays in rodents are used to assess pulmonary carcinogenicity for purposes of hazard identification and potentially for risk characterization. Numerous studies have been confirmed that exposure to titanium dioxide nanoparticles (TiO2 NPs) may result in chronic pulmonary inflammation in both mice...

journal_title：Environmental toxicology

authors： Hong F,Ji L,Zhou Y,Wang L

更新日期：2017-05-01 00:00:00

abstract：:8-Hydroxy-2'-deoxyguanosine (8-OHdG) is the most common biomarker of oxidative DNA damage, it is formed by chemical carcinogens and can be measured in any species. Perfluorooctanoic acid (PFOA) and perfluorononanoic acid (PFNA) are suspected genotoxic carcinogens through induction of reactive oxygen species that are r...

journal_title：Environmental toxicology

authors： Yahia D,Haruka I,Kagashi Y,Tsuda S

更新日期：2016-02-01 00:00:00

abstract：:To study the effects and possible mechanisms of suspected endocrine disrupting compounds (EDCs), a wide variety of assays have been developed. In this work, we generated engineered Escherichia coli biosensor strains that incorporate the ligand-binding domains (LBDs) of the β-subtype estrogen receptors (ERβ) from Solea...

journal_title：Environmental toxicology

authors： Gierach I,Shapero K,Eyster TW,Wood DW

更新日期：2013-04-01 00:00:00

abstract：:The present study was designed to understand the effects of sublethal concentrations of dichlorvos (DIC) on hematological constituent [red blood corpuscles, white blood corpuscles (WBC), mean cell volume, mean corpuscular hemoglobin, mean corpuscular hemoglobin concentration, platelet counts, hemoglobin and hematocrit...

journal_title：Environmental toxicology

authors： Celik I,Yilmaz Z,Turkoglu V

更新日期：2009-04-01 00:00:00

abstract：:Bisphenol A (BPA) has been widely reported to exert endocrine disrupting effects, including the induction of adipogenesis in cultured preadipocytes and intact animals. Because of the potential harm to human health, BPA is being substituted by structurally related bisphenols. Whether or not such BPA analogues are safe ...

journal_title：Environmental toxicology

authors： Ramskov Tetzlaff CN,Svingen T,Vinggaard AM,Rosenmai AK,Taxvig C

更新日期：2020-05-01 00:00:00

abstract：:Nonsmall cell lung cancer (NSCLC) is the most common type of lung cancer with a high mortality rate and still remains a therapeutic challenge. A strategy for targeting NSCLC is to identify agents that are effective against NSCLC cells while sparing normal cells. Dihydromyricetin (DHM) is the major flavonoid component ...

journal_title：Environmental toxicology

authors： Kao SJ,Lee WJ,Chang JH,Chow JM,Chung CL,Hung WY,Chien MH

更新日期：2017-04-01 00:00:00

abstract：:Recent epidemiological studies have revealed significant positive associations between exposure to organochlorine (OC) pesticides and occurrence of the metabolic syndrome and there are a growing number of animal-based studies to support causality. However, the cellular mechanisms linking OC compound exposure and metab...

journal_title：Environmental toxicology

authors： Howell GE 3rd,McDevitt E,Henein L,Mulligan C,Young D

更新日期：2018-09-01 00:00:00

abstract：:Phenols are environmentally important compounds that are widely used in agriculture and industry. Thus, phenols are of interest to environmental toxicologists, which has led to the development of several quantitative structure-activity relationship (QSAR) models. The most successful QSARs have been established for com...

journal_title：Environmental toxicology

authors： Ren S

更新日期：2002-01-01 00:00:00

abstract：:The synergic allergic inflammatory effects of particulate matter (PM) 2.5 and human albumin were investigated in NC/Nga mice, which are hypersensitive to mite allergens. PM2.5 or PM2.5 plus human albumin with aluminum oxide was injected twice intraperitoneally for sensitization. After 7 days, PM2.5 or PM2.5 plus human...

journal_title：Environmental toxicology

authors： Nagaoka K,Ogino K,Ogino N,Ito T,Takemoto K,Ogino S,Seki Y,Hamada H,Fujikura Y

更新日期：2019-07-01 00:00:00

abstract：:Triclosan, a commonly used antimicrobial compound, has been measured in aquatic systems worldwide. This study exposed marine species to triclosan to examine effects primarily on survival and to investigate the formation of the degradation product, methyl-triclosan, in the estuarine environment. Acute toxicity was asse...

journal_title：Environmental toxicology

authors： Delorenzo ME,Keller JM,Arthur CD,Finnegan MC,Harper HE,Winder VL,Zdankiewicz DL

更新日期：2008-04-01 00:00:00

abstract：:Doxorubicin (DOX)-induced cardiomyopathy is a lethal disease. DOX-induced cardiotoxic effects are attributed towards increased redox status and apoptotic signaling. In this study, we show that genistein offers protection against DOX-induced cardio toxicity in the mice model. DOX-mediated increase in serum cardiac trop...

journal_title：Environmental toxicology

authors： Bai Z,Wang Z

更新日期：2019-05-01 00:00:00