Bisphenols B, E, F, and S and 4-cumylphenol induce lipid accumulation in mouse adipocytes similarly to bisphenol A.

abstract：:Doxorubicin (DOX)-induced cardiomyopathy is a lethal disease. DOX-induced cardiotoxic effects are attributed towards increased redox status and apoptotic signaling. In this study, we show that genistein offers protection against DOX-induced cardio toxicity in the mice model. DOX-mediated increase in serum cardiac trop...

journal_title：Environmental toxicology

authors： Bai Z,Wang Z

更新日期：2019-05-01 00:00:00

abstract：:The acute toxicity of the insecticide fenitrothion was measured using four freshwater algae (Chlorella saccharophila, Chlorella vulgaris, Scenedesmus acutus, and Scenedesmus subspicatus) and one cyanobacteria (Pseudanabaena galeata). Insecticide concentrations eliciting 50% growth reduction over 96 hr (EC50) ranged fr...

journal_title：Environmental toxicology

authors： Sabater C,Carrasco JM

更新日期：2001-01-01 00:00:00

abstract：:Long-term exposure of agriculturally used organochloride and organophosphate pesticides have been shown to cause long-lasting hematotoxicity and increased incidence of aplastic anemia in humans. The mechanisms involved in pesticide induced hematotoxicity and the features of toxicity that may play a major role in bone ...

journal_title：Environmental toxicology

authors： Chatterjee S,Basak P,Chaklader M,Das P,Pereira JA,Chaudhuri S,Law S

更新日期：2014-01-01 00:00:00

abstract：:In the present study, responses of the Chinese brown frog (Rana chensinensis) to exposure to di-2-ethylhexyl phthalate (DEHP), a common plasticizer, during the larval period were characterized. The effects of DEHP on metamorphosis rate, thyroid hormone, thyroid histology and the expression of genes involved in the ste...

journal_title：Environmental toxicology

authors： Zhang Y,Li X,Gao J,Wang H

更新日期：2018-01-01 00:00:00

abstract：:The effect of heavy metals and organic compounds on the activity of the enzyme beta-galactosidase in a standardized bioassay has been evaluated, considering future applications in environmental monitoring. The tests were done using a commercial extract of a hydrolase from the eukaryote yeast Kluyveromyces lactis and o...

journal_title：Environmental toxicology

authors： Apartin C,Ronco A

更新日期：2001-01-01 00:00:00

abstract：OBJECTIVES:We evaluated the role of oxidative stress in Sudan IV-induced DNA damage, using human liver-derived HepG2 cells. METHODS:The DNA damaging effects of Sudan IV in HepG2 cells were evaluated by alkaline single cell gel electrophoresis assay and micronucleus test (MNT). To clarify the underlying mechanisms, we ...

journal_title：Environmental toxicology

authors： Zhang Y,An Y,Jiang L,Geng C,Cao J,Jiang L,Zhong L

更新日期：2011-06-01 00:00:00

abstract：:In this study, toxic effects of the cypermethrin in Allium cepa L. cells were investigated. For this aim, we investigated the changes in pigment contents, antioxidant enzymes, mitotic index and chromosomal abnormalities as indicators of toxicity. The seeds were treated with different doses (1.5, 3.0, 6.0 ppm) of cyper...

journal_title：Environmental toxicology

authors： Çavuşoğlu K,Kaya A,Yilmaz F,Yalçin E

更新日期：2012-10-01 00:00:00

abstract：:Lake Elphinstone is a tropical inland water body in the far north of the Fitzroy Catchment in Central Queensland, Australia, and has experienced recurrent toxic cyanoprokaryote blooms since 1997. This article reports on an examination of the environmental conditions of the lake and the concurrent cyanoprokaryote speci...

journal_title：Environmental toxicology

authors： White SH,Fabbro LD,Duivenvoorden LJ

更新日期：2003-12-01 00:00:00

abstract：:The aim of this research was to analyze the effects and the modes of action of elemental sulfur (S(0)) in bioluminescence and respiration of Vibrio fischeri cells and the enzymes crude luciferase, pure catalase, and alcohol dehydrogenase (ADH). Metallic copper removed sulfur and reduced the toxicity of acetone extract...

journal_title：Environmental toxicology

authors： Cetkauskaite A,Pessala P,Södergren A

更新日期：2004-08-01 00:00:00

abstract：:Liver is one of the major target organs of arsenic toxicity and carcinogenesis. Nuclear factor (erythroid-2 related) factor 2 (Nrf2) is a redox-sensitive transcription factor, regulating critically cellular defense responses against the toxic metallic arsenic in many cell types and tissues. This study was conducted to...

journal_title：Environmental toxicology

authors： Li B,Li X,Zhu B,Zhang X,Wang Y,Xu Y,Wang H,Hou Y,Zheng Q,Sun G

更新日期：2013-07-01 00:00:00

abstract：:Bergapten is a natural compound and has potent anticancer activities. In this study, we explored the cytotoxicity of bergapten on colorectal cancer (CRC) cell DLD-1 and LoVo and its underlying mechanisms. We observed that bergapten (30 and 50 μM) decreased the viability of the CRC cells and induced the G0/G1 and sub-G...

journal_title：Environmental toxicology

authors： Lin CP,Lin CS,Lin HH,Li KT,Kao SH,Tsao SM

更新日期：2019-03-01 00:00:00

abstract：:Recent epidemiological studies have revealed significant positive associations between exposure to organochlorine (OC) pesticides and occurrence of the metabolic syndrome and there are a growing number of animal-based studies to support causality. However, the cellular mechanisms linking OC compound exposure and metab...

journal_title：Environmental toxicology

authors： Howell GE 3rd,McDevitt E,Henein L,Mulligan C,Young D

更新日期：2018-09-01 00:00:00

abstract：:The incidence of type 1 diabetes (T1D) and its associated risks of chronic kidney disease or end-stage renal disease development are on the rise. T1D is an autoimmune disease in which insulin-producing beta cells are destroyed. Increased incidence of T1D has been suggested to be a result of environmental factors such ...

journal_title：Environmental toxicology

authors： Pierre TH,Reynolds AS,Seise I,Pilz Z,McHale BJ,Gato WE

更新日期：2020-02-01 00:00:00

abstract：:As a widely used plasticizer in industry, di-2-ethylhexylphthalate (DEHP) can cause testicular toxicity, yet little is known about the potential mechanism. In this study, DEHP exposure dramatically inhibited cellviability and induced apoptosis of mouse GC-1 spg cells. Furthermore, DEHP significantly increased the leve...

journal_title：Environmental toxicology

authors： Gan Y,Yang D,Yang S,Wang J,Wei J,Chen J

更新日期：2020-02-01 00:00:00

abstract：:This study assessed the potential hepatoprotective effect of telmisartan (TLM), a selective angiotensin II type 1 (AT1 ) receptor blocker, on carbon tetrachloride (CCl4 )-induced acute hepatotoxity in rats. Intraperitoneal injection of male Wistar rats with CCl4 1 mL kg-1 , 1:1 mixture with corn oil for 3 days increas...

journal_title：Environmental toxicology

authors： Atawia RT,Esmat A,Elsherbiny DA,El-Demerdash E

更新日期：2017-02-01 00:00:00

abstract：:Cantharidin is one of the major compounds from mylabris and it has cytotoxic effects in many different types of human cancer cells. Previously, we found that cantharidin induced cell death through cell cycle arrest and apoptosis induction in human lung cancer NCI-H460 cells. However, cantharidin-affected DNA damage, r...

journal_title：Environmental toxicology

authors： Hsia TC,Lin JH,Hsu SC,Tang NY,Lu HF,Wu SH,Lin JG,Chung JG

更新日期：2015-09-01 00:00:00

abstract：:Metabolic products are often more toxic than their pharmacological parent compounds. Therefore, the acute and chronic effects of the main metabolites--salicylic acid (SAL), gentisic acid (GEN), and o-hydroxyhippuric acid (HDP)--of acetylsalicylic acid (ASA), the active ingredient in Aspirin and many other pharmaceutic...

journal_title：Environmental toxicology

authors： Marques CR,Abrantes N,Gonçalves F

更新日期：2004-10-01 00:00:00

abstract：:Polybrominated diphenyl ethers (PBDEs) are ubiquitous and prolific contaminant in both the abiotic and biotic environment because of the wide industrial applications of these chemicals. In the present study, the effects of 2,2',4,4'-tetrabrominateddiphenyl ether (BDE-47) and 2,2',4,4',5,5'-hexabromodiphenyl ether (BDE...

journal_title：Environmental toxicology

authors： Meng S,Chen X,Gyimah E,Xu H,Chen J

更新日期：2020-11-01 00:00:00

abstract：:2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) and polychlorinated biphenyls (PCBs) are persistent organic pollutants which coexist in environment, and human are co-exposed to these chemicals. Our present study was aimed to investigate the possible enhanced nonalcoholic fatty liver disease (NAFLD) in ApoE(-/-) mice co-exp...

journal_title：Environmental toxicology

authors： Shan Q,Huang F,Wang J,Du Y

更新日期：2015-12-01 00:00:00

abstract：:Petroleum products-petrol, kerosene, and diesel-composed of volatile organic constituents contribute to air pollution. Exposure of gas station attendants (GSAs) to petroleum products fumes (PPFs) may account for occupation-related predisposition to respiratory toxicity and disease pathogenesis. We simulated GSA exposu...

journal_title：Environmental toxicology

authors： Owumi SE,Elebiyo TC,Oladimeji BN

更新日期：2020-09-07 00:00:00

abstract：:Seasonal changes in developmental stages, condition factor (CF), gonadosomatic index, and plasma vitellogenin (Vtg) concentrations in male and female hornyhead turbot were examined at the wastewater outfall (T1) of the Orange County Sanitation District, and two farfield sites T11 (7.7 km northwest of the outfall) and ...

journal_title：Environmental toxicology

authors： Deng X,Rempel MA,Armstrong J,Schlenk D

更新日期：2007-10-01 00:00:00

abstract：:Titanium dioxide nanoparticles (TiO2 NPs) have been used in environmental management, food, medicine, and industry. But TiO2 NPs have been demonstrated to cross the blood-brain barrier and store up in the brain organization, leading to glutamate-mediated neurotoxicity. However, the neurotoxicity in the brain is not we...

journal_title：Environmental toxicology

authors： Ze X,Su M,Zhao X,Jiang H,Hong J,Yu X,Liu D,Xu B,Sheng L,Zhou Q,Zhou J,Cui J,Li K,Wang L,Ze Y,Hong F

更新日期：2016-06-01 00:00:00

abstract：:A 7 day in situ assay to assess sediment toxicity was carried out per replicate in two sites from Guadalete Estuary (Guad1 and Guad2) (South-West, Spain) using the polychaete Arenicola marina (n = 20) in benthic cages. After the exposure period, a battery of biomarkers were determined to asses the sediment toxicity. F...

journal_title：Environmental toxicology

authors： Ramos-Gómez J,Martín-Díaz ML,Rodríguez A,Riba I,DelValls TA

更新日期：2008-10-01 00:00:00

abstract：:The toxicity and chemical quality of surface water and sediment in the River Traun in Austria were studied because of recurrent fish mortality in some alpine rivers over the last few years. The analyses were carried out on samples collected during winter and summer upstream and downstream of two municipal wastewater t...

journal_title：Environmental toxicology

authors： Latif M,Licek E

更新日期：2004-08-01 00:00:00

abstract：:Ouabain, a cardiotonic steroid, was used for the treatment of heart failure and atrial fibrillation and induces cancer cell apoptosis in many human cancer cells including human leukemia cells. However, there are no reports to show the effects on immune responses in a leukemia mouse model. In this study, WEHI-3 cell ge...

journal_title：Environmental toxicology

authors： Shih YL,Shang HS,Chen YL,Hsueh SC,Chou HM,Lu HF,Lee MZ,Hou HT,Chuang YY,Lee MH,Chen KW,Chung JG

更新日期：2019-05-01 00:00:00

abstract：:Bisphenol A (BPA) and cadmium (Cd) are environmental pollutants that are implicated in potential reproductive effects, including damage to the prostate gland. Their action during puberty requires analysis to determine the relationship of these compounds with the testosterone peak that occurs during this phase. This st...

journal_title：Environmental toxicology

authors： Colleta SJ,Antoniassi JQ,Zanatelli M,Santos FC,Góes RM,Vilamaior PS,Taboga SR

更新日期：2017-01-01 00:00:00

abstract：:Wood dusts, as a group, are categorized as known human carcinogens, but the risks of exposure to specific types of wood dusts and the carcinogenic chemicals they contain are not well studied. Aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor that is linked to the carcinogenic action of specifi...

journal_title：Environmental toxicology

authors： Wilson MJ,Sabbioni G,Rando R,Miller CA 3rd

更新日期：2015-12-01 00:00:00

abstract：:Although marine and coastal environments which are contaminated with xenobiotic organic compounds often become hypoxic during the summer, the interactive effects of hypoxia and xenobiotic exposure on marine species such as teleost fishes remain poorly understood. The expression and activity of monooxygenase enzyme cyt...

journal_title：Environmental toxicology

authors： Rahman MS,Thomas P

更新日期：2018-04-01 00:00:00

abstract：:The aim of this study was to evaluate whether the enzyme-linked immunosorbent assay (ELISA) anti-Adda technique could be used to monitor free microcystins (MCs) in biological samples from fish naturally exposed to toxic cyanobacteria by using receiver operating characteristic (ROC) curve software to establish an optim...

journal_title：Environmental toxicology

authors： Moreno IM,Herrador MÁ,Atencio L,Puerto M,González AG,Cameán AM

更新日期：2011-02-01 00:00:00

abstract：:Recent interest in adverse effects of infrasound on organisms arises from health concerns. We assessed the association between infrasound exposure of 5 Hz at 130 dB and changes of cardiac ultrastructure and function in rats. Thirty-two Sprague-Dawley rats were randomized into control, 1, 7, and 14 days groups for 2 h ...

journal_title：Environmental toxicology

authors： Pei Z,Sang H,Li R,Xiao P,He J,Zhuang Z,Zhu M,Chen J,Ma H

更新日期：2007-04-01 00:00:00