Life-history traits of standard and autochthonous cladocerans: II. Acute and chronic effects of acetylsalicylic acid metabolites.

abstract：:Although marine and coastal environments which are contaminated with xenobiotic organic compounds often become hypoxic during the summer, the interactive effects of hypoxia and xenobiotic exposure on marine species such as teleost fishes remain poorly understood. The expression and activity of monooxygenase enzyme cyt...

journal_title：Environmental toxicology

authors： Rahman MS,Thomas P

更新日期：2018-04-01 00:00:00

abstract：:Toxicity of lead on male reproductive functions has raised wide public concern as environmental lead contamination remains common worldwide. Conflicting and controversial data are available regarding effects of lead on male fertility. More importantly, our knowledge on effects of lead on sperm DNA integrity is signifi...

journal_title：Environmental toxicology

authors： Li C,Zhao K,Zhang H,Liu L,Xiong F,Wang K,Chen B

更新日期：2018-05-01 00:00:00

abstract：:Hexavalent chromium (CrVI) is a highly toxic metal and a major environmental pollutant. Several studies indicate that CrVI exposure adversely affects reproductive function. We reported that maternal Cr exposure resulted in Cr accumulation in the reproductive organs of female offsprings. CrVI can cross the placental ba...

journal_title：Environmental toxicology

authors： Samuel JB,Stanley JA,Sekar P,Princess RA,Sebastian MS,Aruldhas MM

更新日期：2014-05-01 00:00:00

abstract：:Females are born with a finite number of oocyte-containing follicles and ovary damage results in reduced fertility. Cadmium accumulates in the reproductive system, damaging it, and the cigarette smoke is a potential exposure route. Natural therapies are relevant to health benefits and disease prevention. This study ve...

journal_title：Environmental toxicology

authors： Izaguirry AP,Soares MB,Vargas LM,Spiazzi CC,Dos Santos Brum D,Noremberg S,Mendez AS,Santos FW

更新日期：2017-01-01 00:00:00

abstract：:Hypothyroxinemia induced by maternal mild iodine deficiency causes neurological deficits and impairments of brain function in offspring. Hypothyroxinemia is prevalent in developing and developed countries alike. However, the mechanism underlying these deficits remains less well known. Given that the myelin plays an im...

journal_title：Environmental toxicology

authors： Wei W,Wang Y,Dong J,Wang Y,Min H,Song B,Shan Z,Teng W,Xi Q,Chen J

更新日期：2015-11-01 00:00:00

abstract：:Oral submucous fibrosis (OSF) has been indicated as one of the oral potentially malignant disorders. Epidemiological studies have attributed this pathological fibrosis to the habit of areca nuts chewing, which causes chronic inflammation and persistent activation of myofibroblasts in the oral cavity. Hence, it is cruc...

journal_title：Environmental toxicology

authors： Lee PH,Hsieh PL,Liao YW,Yu CC

更新日期：2018-01-01 00:00:00

abstract：:Throughout life, the human eye is continuously exposed to sunlight and artificial lighting. Ambient light exposure can lead to visual impairment and transient or permanent blindness. To mimic benign light stress conditions, Mus musculus eyes were exposed to low-energy UVB radiation, ensuring no severe morphological ch...

journal_title：Environmental toxicology

authors： An MJ,Kim CH,Nam GY,Kim DH,Rhee S,Cho SJ,Kim JW

更新日期：2018-01-01 00:00:00

abstract：:Previous studies indicate that exposure to perfluorooctanesulfonate (PFOS), a ubiquitous and highly persistent environmental contaminant, induces immunotoxicity in mice. However, few studies have specifically assessed the effects of PFOS on inflammation. This study utilized a standard 60-day oral exposure period to as...

journal_title：Environmental toxicology

authors： Dong GH,Zhang YH,Zheng L,Liang ZF,Jin YH,He QC

更新日期：2012-05-01 00:00:00

abstract：:The microbial assay for risk assessment (MARA) is an innovative system based on an array of 11 different microbial species freeze-dried in a 96-well micro-titer plate. Developed for testing the toxicity of chemicals, mixtures, and environmental samples, the assay employs species of a taxonomically diverse range. In ad...

journal_title：Environmental toxicology

authors： Wadhia K

更新日期：2008-10-01 00:00:00

abstract：:Water bodies are routinely monitored for the presence of potentially toxic cyanobacteria; however, the methodology for confirming toxicity is currently complex and expensive. Here we describe the application of gene-based technology to rapidly identify cylindrospermopsin-producing cyanobacteria, specifically, Cylindro...

journal_title：Environmental toxicology

authors： Fergusson KM,Saint CP

更新日期：2003-04-01 00:00:00

abstract：:Dicrotophos is a systemic insecticide with a wide range of applications. We investigated the genotoxicity of dicrotophos using the Ames test, the chromosome aberration test in CHO-K1 cells, and the comet assay in the Hep G2 cells, while this chemicals' toxicity to both the cell lines was evaluated with the MTT assay. ...

journal_title：Environmental toxicology

authors： Wu JC,Chye SM,Shih MK,Chen CH,Yang HL,Chen SC

更新日期：2012-05-01 00:00:00

abstract：:Cancer cell stemness results in the occurrence and progression of tumors and Oct4 (octamer-binding transcription factor) has been confirmed to be a critical contributor and marker of cancer cell stemness. Here, we aimed to explore the underlying mechanisms contributing to Oct4 protein stability, which is necessary for...

journal_title：Environmental toxicology

authors： Xu Y,Xu G,Dang H,Qu W,Chang D,He X,Li M,Wang Q

更新日期：2020-12-03 00:00:00

abstract：:Fluoride exposure is widespread, with drinking water commonly containing natural and artificially added sources of the ion. Ingested fluoride undergoes absorption across the gastric and intestinal epithelia. Previous studies have reported adverse gastrointestinal effects with high levels of fluoride exposure. Here, we...

journal_title：Environmental toxicology

authors： Amadeu de Oliveira F,MacVinish LJ,Amin S,Herath D,Jeggle P,Mela I,Pieri M,Sharma C,Jarvis GE,Levy FM,Santesso MR,Khan ZN,Leite AL,Oliveira RC,Buzalaf MAR,Edwardson JM

更新日期：2018-01-01 00:00:00

abstract：:Ouabain, a cardiotonic steroid, was used for the treatment of heart failure and atrial fibrillation and induces cancer cell apoptosis in many human cancer cells including human leukemia cells. However, there are no reports to show the effects on immune responses in a leukemia mouse model. In this study, WEHI-3 cell ge...

journal_title：Environmental toxicology

authors： Shih YL,Shang HS,Chen YL,Hsueh SC,Chou HM,Lu HF,Lee MZ,Hou HT,Chuang YY,Lee MH,Chen KW,Chung JG

更新日期：2019-05-01 00:00:00

abstract：:Metals such as lead (Pb), magnesium (Mg), and iron (Fe) are ubiquitous in the environment as a result of natural occurrence and anthropogenic activities. Although Mg, Fe, and others are considered essential elements, high level of exposure has been associated with severe adverse health effects including cardiovascular...

journal_title：Environmental toxicology

authors： Sanders T,Liu YM,Tchounwou PB

更新日期：2015-12-01 00:00:00

abstract：:In May of 2006 we suddenly began to observe neural tube defects (NTDs) in embryos of untreated control mice. We hypothesized the mice were being exposed unknowingly to a teratogenic agent and investigated the cause. Our results suggested that NTDs were not resulting from bedding material, feed, strain, or source of th...

journal_title：Environmental toxicology

authors： Mallela MK,Werre SR,Hrubec TC

更新日期：2011-11-01 00:00:00

abstract：:We performed an interspecies comparison for the human hepatoma cell line HepG2 and the eukaryotic single cell organism Tetrahymena pyriformis (T. pyriformis) for 17 xenobiotics with diverse structures and four metals. The cytotoxicity was assessed by four different cell viability assays (3-[4,5-dimethylthiazol-2-yl]-2...

journal_title：Environmental toxicology

authors： Rudzok S,Krejči S,Graebsch C,Herbarth O,Mueller A,Bauer M

更新日期：2011-04-01 00:00:00

abstract：:Laboratory toxicity tests were performed to obtain more data on the toxicity of ammonia to saltwater organisms. The standards for in-stream ammonia limits in marine environments presently are based on toxicity tests involving both freshwater and saltwater organisms. Acute tests (48 and 96 h) were performed at 20 degre...

journal_title：Environmental toxicology

authors： Boardman GD,Starbuck SM,Hudgins DB,Li X,Kuhn DD

更新日期：2004-04-01 00:00:00

abstract：:Numerous studies have shown that rutin has anticancer effects. We have previously reported that rutin induced cell cycle arrest and apoptosis in murine leukemia WEHI-3 cells in vitro and in vivo. However, there are no data showing that rutin inhibits human leukemia HL-60 cells in vivo in a murine xenograft animal mode...

journal_title：Environmental toxicology

authors： Lin JP,Yang JS,Lin JJ,Lai KC,Lu HF,Ma CY,Sai-Chuen Wu R,Wu KC,Chueh FS,Gibson Wood W,Chung JG

更新日期：2012-08-01 00:00:00

abstract：:We cloned the full-length cDNA sequence of xenobiotic metabolizing cytochrome P4501A (CYP1A) gene from the yellow catfish (Pelteobagrus fulvidraco, Siluriformes, Bagridae). P. fulvidraco is a commercially important fish generally distributed in Southeast Asian countries and Korea. This is the first report of any xenob...

journal_title：Environmental toxicology

authors： Kim JH,Hwang DS,Son KH,Raisuddin S,Ki JS,Lee JS,Han KN

更新日期：2008-06-01 00:00:00

abstract：:Long non-coding RNA (lncRNA) plays a critical role in male germline development. Atrazine (AZ) as an environmental endocrine disrupting chemical (EDCs) can induce male reproductive toxicity in amphibians. Our previous studies demonstrated that AZ can alter gene and circular RNA (circRNA) expression of damaged testes i...

journal_title：Environmental toxicology

authors： Sai L,Qu B,Zhang J,Liu J,Jia Q,Bo C,Zhang Y,Yu G,Han R,Peng C

更新日期：2019-04-01 00:00:00

abstract：:Di(2-ethylhexyl) phthalate, which is a ubiquitous environmental contaminant because of its extensive use as a plasticizer, is a potential nongenotoxic carcinogen. To assess the effects of DEHP exposure on the cytoskeleton of Chironomus, we characterized full-length cDNA sequences of the calponin gene from Chironomus r...

journal_title：Environmental toxicology

authors： Park K,Kwak IS

更新日期：2009-12-01 00:00:00

abstract：:Kupffer cells (KCs) are important in hepatic homeostasis and responses to xenobiotics. KCs are activated on interaction with endotoxin, releasing cytokines, and reactive oxygen species normally associated with increased gene expression, cellular growth, or hepatic injury. Ethanol-induced endotoxemia is one means of KC...

journal_title：Environmental toxicology

authors： Owumi SE,Corthals SM,Uwaifo AO,Kamendulis LM,Klaunig JE

更新日期：2014-08-01 00:00:00

abstract：:Inflammation generated by environmental toxicants including pesticides could be one of the factors underlying neuronal cell damage in neurodegenerative diseases. In this study, we investigated the mechanisms by which inflammatory responses contribute to apoptosis in PC12 cells treated with diquat. We found that diquat...

journal_title：Environmental toxicology

authors： Choi SE,Park YS,Koh HC

更新日期：2018-10-01 00:00:00

abstract：:The effect of heavy metals and organic compounds on the activity of the enzyme beta-galactosidase in a standardized bioassay has been evaluated, considering future applications in environmental monitoring. The tests were done using a commercial extract of a hydrolase from the eukaryote yeast Kluyveromyces lactis and o...

journal_title：Environmental toxicology

authors： Apartin C,Ronco A

更新日期：2001-01-01 00:00:00

abstract：:Micronucleus induction by the diarrhetic shellfish toxin okadaic acid (OA) was investigated in two intestinal models, cultured human Caco-2 cells and colon epithelial cells of mice treated in vivo. Exposure to OA for 4 and 24 h induced dose-responsive increases in the frequency of micronucleated Caco-2 cells; the mini...

journal_title：Environmental toxicology

authors： Le Hégarat L,Jacquin AG,Bazin E,Fessard V

更新日期：2006-02-01 00:00:00

abstract：:Wood dusts, as a group, are categorized as known human carcinogens, but the risks of exposure to specific types of wood dusts and the carcinogenic chemicals they contain are not well studied. Aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor that is linked to the carcinogenic action of specifi...

journal_title：Environmental toxicology

authors： Wilson MJ,Sabbioni G,Rando R,Miller CA 3rd

更新日期：2015-12-01 00:00:00

abstract：:Acute toxicities of perfluorooctane sulfonate (PFOS) and perfluorooctanoic acid (PFOA) were tested on four freshwater species and three plant species. PFOS was more toxic than PFOA for all species tested in this study. Similar time-response patterns of PFOS and PFOA toxicity were observed for each tested species. Valu...

journal_title：Environmental toxicology

authors： Li MH

更新日期：2009-02-01 00:00:00

abstract：:An important disturbance of anthropogenic origin frequently occurring in freshwater ecosystems is a rise in the concentration of heavy metals in solution, among which copper stands out due to its known toxicity. However, the study of the chemical behavior of copper in solution is highly dependent on pH. In this study,...

journal_title：Environmental toxicology

authors： Gagneten AM,Vila I

更新日期：2001-10-01 00:00:00

abstract：:The aim of this study was to investigate the signaling pathways involved in the cyclooxygenase (COX)-2 regulation induced by nonylphenol (NP) in mouse testis Sertoli TM4 cells. Our results showed that treatment of TM4 cells with NP increased COX-2 protein expression and interleukin-6 (IL)-6 and prostaglandin E2 (PGE2)...

journal_title：Environmental toxicology

authors： Liu X,Nie S,Huang D,Xie M

更新日期：2015-09-01 00:00:00