Gamma interferon suppresses erythropoiesis via interleukin-15.

abstract：:Studies with animal models have demonstrated that viral respiratory tract infections suppress bacterial clearance processes in the lung and that this alteration in host defenses appears to explain the excessive mortality from bacterial pneumonia during influenza epidemics. However, since the pathogenesis of postinflue...

journal_title：Infection and immunity

authors： Nugent KM,Pesanti EL

更新日期：1983-12-01 00:00:00

abstract：:The gastric spirillum Helicobacter felis, originally isolated from the cat stomach, colonizes the stomachs of germfree rats. Studies were designed to examine the pathological and serological responses of germfree rats inoculated orally with H. felis. At 2 weeks postinoculation, the gastric mucosa of germfree rats had ...

journal_title：Infection and immunity

authors： Fox JG,Lee A,Otto G,Taylor NS,Murphy JC

更新日期：1991-03-01 00:00:00

abstract：:Bordetella parapertussis, a respiratory tract pathogen commonly regarded as noninvasive, was found to invade HeLa 229 cell monolayers. Following treatment of the monolayers with gentamicin, numbers of viable B. parapertussis recovered were comparable to those of invasive Salmonella and Shigella isolates. Invasion occu...

journal_title：Infection and immunity

authors： Ewanowich CA,Sherburne RK,Man SF,Peppler MS

更新日期：1989-04-01 00:00:00

abstract：:We examined the secretion of antimicrobial proteins and peptides into surgically isolated and continuously perfused segments of rat small intestine. Up to nine discrete antimicrobial molecules appeared in the intestinal perfusates following intravenous administration of bethanechol, a cholinergic agonist, or intralume...

journal_title：Infection and immunity

authors： Qu XD,Lloyd KC,Walsh JH,Lehrer RI

更新日期：1996-12-01 00:00:00

abstract：:During persistence of nonencapsulated Haemophilus influenzae in the respiratory tracts of patients with chronic bronchitis, the major outer membrane proteins (MOMPs) P2 and P5 show antigenic drift. The hypothesis that appearance of antigenic variants is the consequence of antibody-dependent selection was tested in a r...

journal_title：Infection and immunity

authors： Vogel L,Duim B,Geluk F,Eijk P,Jansen H,Dankert J,vanAlphen L

更新日期：1996-03-01 00:00:00

abstract：:After interaction with tracheal epithelial cells, Bordetella pertussis induces the secretion of interleukin-6. This secretion is dependent on the expression of adenylate cyclase-hemolysin by the bacterium but not on the expression of other characterized bacterial toxins or adhesins. This finding confirms the important...

journal_title：Infection and immunity

authors： Bassinet L,Fitting C,Housset B,Cavaillon JM,Guiso N

更新日期：2004-09-01 00:00:00

abstract：:Intrauterine infections lead to serious complications for mother and fetus, including preterm birth, maternal and fetal death, and neurological sequelae in the surviving offspring. Improving maternal and child heath is a global priority. Yet, the development of strategies to prevent and treat pregnancy-related disease...

journal_title：Infection and immunity

authors： Lowe DE,Robbins JR,Bakardjiev AI

更新日期：2018-05-22 00:00:00

abstract：:Immunization of monkeys with the 82-kDa rhoptry protein (p82) of Plasmodium falciparum can protect them against a lethal blood stage challenge, and monoclonal antibodies to p82 inhibit parasite growth in vitro. The role that a p82-specific immune response might play in human immunity to the parasite is not known. To d...

journal_title：Infection and immunity

authors： Howard RF,Jensen JB,Franklin HL

更新日期：1993-07-01 00:00:00

abstract：:A differential-display PCR procedure identified the capsular assembly gene kpsD after Escherichia coli type 1 fimbrial binding to mannose-coated Sepharose beads. Limiting-dilution reverse-transcribed PCRs confirmed down-regulation of the kpsD gene, and Northern blot and lacZ fusion analyses showed down-regulation of t...

journal_title：Infection and immunity

authors： Schwan WR,Beck MT,Hultgren SJ,Pinkner J,Woolever NL,Larson T

更新日期：2005-02-01 00:00:00

abstract：:Four strains of Staphylococcus aureus of a phage type other than the second group, isolated from patients with impetigo and Ritter's disease, were found to produce an exotoxin similar to those reported by Melish et al. (1972), Kapral and Miller (1971), and Arbuthnott et al. (1973). This toxin could elicit a general ex...

journal_title：Infection and immunity

authors： Kondo I,Sakurai S,Sarai Y

更新日期：1974-10-01 00:00:00

abstract：:In experimental visceral leishmaniasis, in which the tissue macrophage is the target, in vivo responsiveness to conventional chemotherapy (pentavalent antimony [Sb]) requires a T-cell-dependent mechanism. To determine if this mechanism involves gamma interferon (IFN-gamma)-induced activation and/or specific IFN-gamma-...

journal_title：Infection and immunity

authors： Murray HW,Delph-Etienne S

更新日期：2000-01-01 00:00:00

abstract：:Sephadex G-200 filtration was used for fractionating dengue type 2 (DEN-2)-infected suckling mouse brain (SMB) supernatant fluids. The high-molecular-weight fraction, which was eluted in the void volume, showed no increase in type specificity when tested against immune ascitic fluid to the four prototype dengue viruse...

journal_title：Infection and immunity

authors： Cornesky RA,Hammon WM,Atchison RW,Sather GE

更新日期：1972-12-01 00:00:00

abstract：:Two glucosyltransferase genes from Streptococcus mutans GS-5, gtfB and gtfC, have been previously isolated and sequenced in this laboratory. In the present communication a third gtf gene, gtfD, was isolated and characterized. Isolation of the gene involved a novel procedure utilizing the integration plasmid pVA891. A ...

journal_title：Infection and immunity

authors： Hanada N,Kuramitsu HK

更新日期：1989-07-01 00:00:00

abstract：:The expression of T cell differentiation markers is known to increase during Mycobacterium tuberculosis infection, and yet the biological role of such markers remains unclear. We examined the requirement of the T cell differentiation marker killer cell lectin-like receptor G1 (KLRG1) during M. tuberculosis infection u...

journal_title：Infection and immunity

authors： Cyktor JC,Carruthers B,Stromberg P,Flaño E,Pircher H,Turner J

更新日期：2013-04-01 00:00:00

abstract：:The role of capsule in the adherence of Haemophilus influenzae type b to human epithelial cells in vitro was examined. A group of 30 nonadherent isolates did not differ in degree of encapsulation compared with their respective adherent variants. Furthermore, capsule-deficient mutants of both nonadherent and adherent v...

journal_title：Infection and immunity

authors： LiPuma JJ,Gilsdorf JR

更新日期：1987-09-01 00:00:00

abstract：:The concept that relates low virulence of certain alphaviruses to low viremia and efficient vascular clearance of virus was tested in guinea pigs. Previously published studies with hamsters suggested that virulent strains maintain high viremias primarily because they are cleared inefficiently from the blood. In the pr...

journal_title：Infection and immunity

authors： Jahrling PB,Heisey GB,Hesse RA

更新日期：1977-08-01 00:00:00

abstract：:Extracellular protease activity was measured in liquid cultures of representative strains from six serotypes of Legionella pneumophila. A variety of substrates were degraded, including denatured casein, skim milk, gelatin, and hide powder azure, but not elastin. ...

journal_title：Infection and immunity

authors： Thompson MR,Miller RD,Iglewski BH

更新日期：1981-10-01 00:00:00

abstract：:Previous work (P. Castric, F. J. Cassels, and R. W. Carlson, J. Biol. Chem. 276:26479-26485, 2001) has shown the Pseudomonas aeruginosa 1244 pilin glycan to be covalently bound to a serine residue. N-terminal sequencing of pilin fragments produced from endopeptidase treatment and identified by reaction with a glycan-s...

journal_title：Infection and immunity

authors： Comer JE,Marshall MA,Blanch VJ,Deal CD,Castric P

更新日期：2002-06-01 00:00:00

abstract：:Dendritic cells (DC) suffer a maturation defect following interaction with erythrocytes infected with malaria parasites and become unable to induce protective malaria liver-stage immunity. Here we show that, by contrast, maturation-arrested DC in vitro are capable of the successful induction of antigen-specific gamma ...

journal_title：Infection and immunity

authors： Pouniotis DS,Proudfoot O,Bogdanoska V,Apostolopoulos V,Fifis T,Plebanski M

更新日期：2004-09-01 00:00:00

abstract：:Strain superinfection occurs when a second pathogen strain infects a host already carrying a primary strain. Anaplasma marginale superinfection occurs when the second strain carries a variant repertoire different from that of the primary strain, and the epidemiologic consequences depend on the relative efficiencies of...

journal_title：Infection and immunity

authors： Galletti MF,Ueti MW,Knowles DP Jr,Brayton KA,Palmer GH

更新日期：2009-04-01 00:00:00

abstract：:Mice infected with various strains of Salmonella enteritidis and S. typhimurium were found to be more sensitive to the cell wall lipopolysaccharide (LPS) extracted from certain strains of Salmonella than noninfected mice. This hypersensitivity was induced by those smooth or rough strains which possessed a polysacchari...

journal_title：Infection and immunity

authors： Kawakami M,Hara Y,Osawa N

更新日期：1971-11-01 00:00:00

abstract：:The role of the spleen in hepatic amoebiasis in hamsters was studied. In hamsters receiving an intrahepatic inoculation of 10(5) trophozoites of axenic Entamoeba histolytica at 7 or 14 days postsplenectomy, the mean weight of metastatic foci increased significantly when compared with sham-splenectomized or intact cont...

journal_title：Infection and immunity

authors： Ghadirian E,Meerovitch E

更新日期：1981-02-01 00:00:00

abstract：:Salmonella enterica serovar Typhi is a human-restricted Gram-negative bacterial pathogen responsible for causing an estimated 27 million cases of typhoid fever annually, leading to 217,000 deaths, and current vaccines do not offer full protection. The O-antigen side chain of the lipopolysaccharide is an immunodominant...

journal_title：Infection and immunity

authors： Kintz E,Heiss C,Black I,Donohue N,Brown N,Davies MR,Azadi P,Baker S,Kaye PM,van der Woude M

更新日期：2017-03-23 00:00:00

abstract：:The comparative immunogenicity of the two cross-reacting group 6 pneumococcal capsular polysaccharides, type 6A(6) and type 6B(26), was studied with hyperimmune rabbit typing antisera and with sera from adult volunteers injected with polyvalent pneumococcal vaccines containing either 50 mug of type 6A (U.S. designatio...

journal_title：Infection and immunity

authors： Robbins JB,Lee CJ,Rastogi SC,Schiffman G,Henrichsen J

更新日期：1979-12-01 00:00:00

abstract：:A gene encoding the cytotoxic enterotoxin (Act) from Aeromonas hydrophila was hyperexpressed with the pET, pTRX, and pGEX vector systems. Maximum toxin yield was obtained with the pTRX vector. Approximately 40 to 60% of Act was in a soluble form with the pTRX and pET vector systems. The toxin protein was purified to h...

journal_title：Infection and immunity

authors： Ferguson MR,Xu XJ,Houston CW,Peterson JW,Coppenhaver DH,Popov VL,Chopra AK

更新日期：1997-10-01 00:00:00

abstract：:Human plasma was bactericidal for small numbers of Klebsiella pneumoniae, but larger numbers grew slowly over a period of 24 h. Human polymorphs in a clot of autologous plasma had a bacteriostatic effect on relatively large numbers of bacteria for up to 24 h and were much more effective than plasma alone. The bacteric...

journal_title：Infection and immunity

authors： Ward CG,Hammond JS,Bullen JJ

更新日期：1986-03-01 00:00:00

abstract：:UV-inactivated Sendai virus is mitogenic for murine splenocytes, whereas infectious Sendai virus kills spleen cells in vitro. The isolated hemagglutinin-neuraminidase (HN) and fusion (F) glycoproteins of Sendai virus are also mitogenic for cultured mouse spleen cells. A mixture of these glycoproteins (1 microgram/well...

journal_title：Infection and immunity

authors： Kizaka S,Goodman-Snitkoff G,McSharry JJ

更新日期：1983-05-01 00:00:00

abstract：:Minor salivary glands of the oral mucosa in healthy monkeys (Macaca fascicularis and Macaca mulatta) contain organized structural units suitable for recognizing and processing antigens. A previous study of M. fascicularis monkeys provided experimental evidence of retrograde access of oral antigens deep into the minor ...

journal_title：Infection and immunity

authors： Nair PN,Schroeder HE

更新日期：1983-07-01 00:00:00

abstract：:Previous studies have demonstrated that expression of virulence in Shigella spp. is controlled by growth temperature. To study the regulation of virulence (vir) genes, we set out to develop a rapid, easily-assayed phenotype with which to measure expression of virulence. This report described a procedure for isolating ...

journal_title：Infection and immunity

authors： Maurelli AT,Curtiss R 3rd

更新日期：1984-09-01 00:00:00

abstract：:Borrelia burgdorferi, a causative agent of Lyme borreliosis, is a zoonotic pathogen that survives in nutrient-limited environments within a tick, prior to transmission to its mammalian host. Survival under these prolonged nutrient-limited conditions is thought to be similar to survival during stationary phase, which i...

journal_title：Infection and immunity

authors： Fazzino L,Tilly K,Dulebohn DP,Rosa PA

更新日期：2015-12-01 00:00:00