A computational study on the influence of catheter-delivered intravascular probes on blood flow in a coronary artery model.

Abstract:

:Catheter-delivered intravascular probes are widely used in clinical practice to measure coronary arterial velocity and pressure, but the artefactual effect of the probe on the variables being measured is not well characterised. A coronary artery was simulated with a 180 degrees curved tube 3mm in diameter and the effect of catheters of different diameters was modelled numerically under pulsatile flow conditions. The presence of a catheter increased pressure by 1.3-4.3 mmHg depending on its diameter, and reduced velocity-pressure phase-lag. For an ultrasound sample volume 5mm downstream from the probe tip, the underestimation in velocity measurement attributed to catheter blockage is approximately 15-21% for an average inlet velocity of 0.1m/s. The velocity measurement error is lower at higher mean flow velocity. Accuracy of clinical velocity measurements could be improved by moving the sample volume farther downstream from the probe tip, because the centrifugal pressure gradient intrinsic to the curvature promotes re-development of flow.

journal_name

J Biomech

journal_title

Journal of biomechanics

authors

Torii R,Wood NB,Hughes AD,Thom SA,Aguado-Sierra J,Davies JE,Francis DP,Parker KH,Xu XY

doi

10.1016/j.jbiomech.2006.11.004

subject

Has Abstract

pub_date

2007-01-01 00:00:00

pages

2501-9

issue

11

eissn

0021-9290

issn

1873-2380

pii

S0021-9290(06)00446-5

journal_volume

40

pub_type

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