Abstract:
:Sulfamate is an analogue of thiosulfate, and the sodium and potassium salts of sulfamic acid inhibited the chemolithoautotrophic growth on thiosulfate of Acidithiobacillus ferrooxidans and Halothiobacillus neapolitanus. The chemo-organotrophic growth of Paracoccus versutus on sucrose was similarly inhibited by sulfamate. Thiosulfate oxidation by suspensions of H. neapolitanus was, however, unaffected by sulfamate, showing that sulfamate did not directly affect thiosulfate uptake, activation or oxidation. Inhibition of P. versutus was not relieved by cysteine and methionine, indicating that sulfate uptake and sulfur amino acid biosynthesis were not directly affected by sulfamate. Sulfamate was not degraded by any of the bacteria, and so could not serve as an alternative to thiosulfate as an energy-yielding substrate. Sulfamate is also an analogue of ammonia and might act like hydrazine by inhibiting ammonium uptake or an essential enzyme activity.
journal_name
FEMS Microbiol Lettjournal_title
FEMS microbiology lettersauthors
Lusty JR,Hughes MN,Kelly DPdoi
10.1111/j.1574-6968.2006.00437.xsubject
Has Abstractpub_date
2006-11-01 00:00:00pages
70-3issue
1eissn
0378-1097issn
1574-6968pii
FML437journal_volume
264pub_type
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