Schistosoma japonicum reinfection after praziquantel treatment causes anemia associated with inflammation.

abstract：:Urogenital Chlamydia serovars replicating in reproductive epithelium pose a unique challenge to host immunity and vaccine development. Previous studies have shown that CD4 T cells are necessary and sufficient to clear primary Chlamydia muridarum genital tract infections in the mouse model, making a protective CD4 T ce...

journal_title：Infection and immunity

authors： Johnson RM,Yu H,Kerr MS,Slaven JE,Karunakaran KP,Brunham RC

更新日期：2012-06-01 00:00:00

abstract：:A set of four monoclonal antibodies was produced against a highly purified pepsin extract of type 5 streptococcal M protein. Three of the four antibodies cross-reacted with purified M proteins from heterologous serotypes and opsonized the respective heterologous organisms. Our studies suggest that monoclonal antibodie...

journal_title：Infection and immunity

authors： Dale JB,Beachey EH

更新日期：1984-10-01 00:00:00

abstract：:Tox-+ staphylococcal strains, as opposed to Tox-minus strains, produce epidermal exfoliation within 18 h after direct subcutaneous or intraperitoneal injection into newborn mice. The extracellular product responsible for exfoliation is termed exfoliative toxin (ET). When culture supernatant fluid from the plasmid-cure...

journal_title：Infection and immunity

authors： Keyhani M,Rogolsky M,Wiley BB,Glasgow LA

更新日期：1975-07-01 00:00:00

abstract：:Type II heat-labile enterotoxin (LT-II) from Escherichia coli 41 was purified and compared with prototype LT-II encoded by genes from E. coli SA53. Both toxins were oligomeric proteins consisting of polypeptides A (Mr, 28,000) and B (Mr, 11,800). The A polypeptides were cleaved by trypsin into fragments A1 (Mr, 21,000...

journal_title：Infection and immunity

authors： Guth BE,Twiddy EM,Trabulsi LR,Holmes RK

更新日期：1986-11-01 00:00:00

abstract：:Cells of several strains of Streptococcus gordonii attached in much higher numbers to experimental pellicles formed from samples of submandibular or parotid saliva on hydroxyapatite (HA) beads than to buffer controls. The nature of the salivary components responsible were investigated by preparing experimental pellicl...

journal_title：Infection and immunity

authors： Gibbons RJ,Hay DI,Schlesinger DH

更新日期：1991-09-01 00:00:00

abstract：:Growing Streptococcus gordonii Spp+ phase variants, which have normal levels of glucosyltransferase (GTF) activity, use sucrose to promote their accumulation on surfaces by forming a cohesive bacterium-insoluble glucan polymer mass (BPM). Spp- phase variants, which have lower levels of GTF activity, do not form BPMs a...

journal_title：Infection and immunity

authors： Vickerman MM,Jones GW

更新日期：1992-10-01 00:00:00

abstract：:When immunocompetent mice are inoculated with Borrelia burgdorferi, they develop acute arthritis and carditis that undergo spontaneous regression despite the persistence of infection. Specific T- and/or B-cell immunity appears to be necessary for resolution of disease manifestations. Humoral immune responses to B. bur...

journal_title：Infection and immunity

authors： Bockenstedt LK,Barthold S,Deponte K,Marcantonio N,Kantor FS

更新日期：1993-05-01 00:00:00

abstract：:Commercial fluid used for peritoneal lavage in peritonitis and in peritoneal dialysis suppressed the activity of peripheral blood leukocytes as measured by chemiluminescence, phagocytosis, and bacterial killing. Suppression was found to be due to the low pH and high osmolality of the fluid. The pH was adjusted to noni...

journal_title：Infection and immunity

authors： Duwe AK,Vas SI,Weatherhead JW

更新日期：1981-07-01 00:00:00

abstract：:Although Salmonella enterica serovar Typhimurium can undergo phase variation to alternately express two different types of flagellin subunit proteins, FljB or FliC, no biological function for this phenomenon has been described. In this investigation, we constructed phase-locked derivatives of S. enterica serovar Typhi...

journal_title：Infection and immunity

authors： Ikeda JS,Schmitt CK,Darnell SC,Watson PR,Bispham J,Wallis TS,Weinstein DL,Metcalf ES,Adams P,O'Connor CD,O'Brien AD

更新日期：2001-05-01 00:00:00

abstract：:Intracellular growth of Legionella pneumophila occurs in a replication vacuole constructed by host proteins that regulate vesicular traffic from the host endoplasmic reticulum (ER). This process is promoted by a combination of approximately 300 Icm/Dot translocated substrates (IDTS). One of these proteins, Ceg9, was p...

journal_title：Infection and immunity

authors： Haenssler E,Ramabhadran V,Murphy CS,Heidtman MI,Isberg RR

更新日期：2015-09-01 00:00:00

abstract：:Mice were rendered deficient in B-cell activity by treatment with anti-mu antibody from birth. These animals were then infected intranasally with murine Chlamydia trachomatis (murine pneumonitis agent [MoPn]). They produced neither local nor systemic antibody to MoPn but had intact delayed-type hypersensitivity to MoP...

journal_title：Infection and immunity

authors： Williams DM,Grubbs B,Schachter J

更新日期：1987-10-01 00:00:00

abstract：:Phytohemagglutinin is able to trigger interferon synthesis in spleen cell cultures from nude (nu/nu) mice as effectively as in splenic cell cultures from haired, control (nu/+), thymus-bearing mice. A minor theta-bearing cell population present in the spleen of nude mice appears essential to phytohemagglutinin interfe...

journal_title：Infection and immunity

authors： Wietzerbin J,Stefanos S,Falcoff R,Lucero M,Catinot L,Falcoff E

更新日期：1978-09-01 00:00:00

abstract：:Female guinea pigs were immunized with viable or UV light-inactivated chlamydiae (agent of guinea pig inclusion conjunctivitis), belonging to the species Chlamydia psittaci, by intravenous, subcutaneous, oral, or ocular routes. All animals were then inoculated vaginally with viable chlamydiae to determine the extent o...

journal_title：Infection and immunity

authors： Rank RG,Batteiger BE,Soderberg LS

更新日期：1990-08-01 00:00:00

abstract：:Elicited macrophages from 129sv mice with a functional deletion of the natural-resistance-associated macrophage protein 1 gene (Nramp1) were shown to be as susceptible as wild-type mice to infection with the Chlamydia trachomatis mouse pneumonitis and L3 serovars and to Chlamydia pneumoniae. Furthermore, the two group...

journal_title：Infection and immunity

authors： Pal S,Peterson EM,de La Maza LM

更新日期：2000-08-01 00:00:00

abstract：:The innate immune system recognizes pathogen-associated molecular patterns (PAMPs) through pattern recognition receptors (PRR) and transduces downstream signaling to activate the host defense. Here we report that in addition to direct PAMP-PRR interactions, live Candida albicans cells can release soluble factors to ac...

journal_title：Infection and immunity

authors： Cheng SC,Chai LY,Joosten LA,Vecchiarelli A,Hube B,Van Der Meer JW,Kullberg BJ,Netea MG

更新日期：2010-01-01 00:00:00

abstract：:B-cell-deficient C57B1/6J mice (suppressed from birth with goat anti-mu) and controls (treated from birth with normal goat serum) were infected with Trypanosoma rhodesiense. There was a significant (P less than 0.01) decrease in duration of survival of the mu-suppressed mice compared with that of controls. Whereas bot...

journal_title：Infection and immunity

authors： Campbell GH,Esser KM,Weinbaum FI

更新日期：1977-11-01 00:00:00

abstract：:Mosquitoes are infected with Plasmodium falciparum by taking a blood meal from a gametocyte carrier. Since a mosquito takes a volume of 1 to 2 microl, a blood meal may contain 1 x 10(4) to 3 x 10(4) leukocytes (WBC). The majority of WBC are composed of neutrophils which may phagocytose and kill developing gametes insi...

journal_title：Infection and immunity

authors： Lensen AH,Bolmer-Van de Vegte M,van Gemert GJ,Eling WM,Sauerwein RW

更新日期：1997-09-01 00:00:00

abstract：:Tuberculosis continues to ravage humanity, killing 2 million people yearly. Most cases occur in areas of the world to which the disease is endemic, where almost everyone is vaccinated early in life with Mycobacterium bovis BCG, the currently available vaccine against tuberculosis. Thus, while more-potent vaccines are ...

journal_title：Infection and immunity

authors： Horwitz MA,Harth G,Dillon BJ,Maslesa-Galic S

更新日期：2005-08-01 00:00:00

abstract：:LT-IIa and LT-IIb, the type II heat-labile enterotoxins of Escherichia coli, are closely related in structure and function to cholera toxin and LT-I, the type I heat-labile enterotoxins of Vibrio cholerae and E. coli, respectively. Recent studies from our group demonstrated that LT-IIa and LT-IIb are potent systemic a...

journal_title：Infection and immunity

authors： Nawar HF,Arce S,Russell MW,Connell TD

更新日期：2005-03-01 00:00:00

abstract：:Virulent Streptococcus suis serotype 2 strains are invasive extracellular bacteria causing septicemia and meningitis in piglets and humans. One objective of this study was to elucidate the function of complement in innate immune defense against S. suis. Experimental infection of wild-type (WT) and C3(-/-) mice demonst...

journal_title：Infection and immunity

authors： Seitz M,Beineke A,Singpiel A,Willenborg J,Dutow P,Goethe R,Valentin-Weigand P,Klos A,Baums CG

更新日期：2014-06-01 00:00:00

abstract：:The fungus Cryptococcus neoformans has emerged as a major cause of meningoencephalitis worldwide. Host response to the fungus involves both innate and adaptive immunity, but fungal genes that modulate these processes are poorly understood. Previous studies demonstrated attenuated virulence of a mutant of a virulence-a...

journal_title：Infection and immunity

authors： Qiu J,Olszewski MA,Williamson PR

更新日期：2013-03-01 00:00:00

abstract：:Murine cerebral malaria (CM) induced by Plasmodium berghei ANKA kills susceptible mice within 24 to 48 h of onset of symptoms and is characterized by the production of inflammatory cytokines in the brain. C57BL/6J mice are sensitive to lethal CM, while A/J mice are resistant. These strains of mice were immunized with ...

journal_title：Infection and immunity

authors： Jennings VM,Lal AA,Hunter RL

更新日期：1998-12-01 00:00:00

abstract：:Poly-N-acetyl-glucosamine (PNAG) is a staphylococcal surface polysaccharide influencing biofilm formation that is also under investigation for its vaccine potential. Antibodies that bind to PNAG with either low (<15%) or high (>90%) levels of acetate are superior at opsonic and protective activity compared with antibo...

journal_title：Infection and immunity

authors： Cerca N,Jefferson KK,Maira-Litrán T,Pier DB,Kelly-Quintos C,Goldmann DA,Azeredo J,Pier GB

更新日期：2007-07-01 00:00:00

abstract：:The antiphagocytic effect of the Staphylococcus aureus capsule is known to be related to its ability to interfere with opsonization by normal human serum. In this study, evidence is presented with isolated cell surface components which indicates that the capsule hinders opsonization by masking cell wall peptidoglycan....

journal_title：Infection and immunity

authors： Wilkinson BJ,Peterson PK,Quie PG

更新日期：1979-02-01 00:00:00

abstract：:Bacillus anthracis is surrounded by a polypeptide capsule composed of poly-gamma-d-glutamic acid (gammaDPGA). In a previous study, we reported that a monoclonal antibody (MAb F26G3) reactive with the capsular polypeptide is protective in a murine model of pulmonary anthrax. The present study examined a library of six ...

journal_title：Infection and immunity

authors： Kozel TR,Thorkildson P,Brandt S,Welch WH,Lovchik JA,AuCoin DP,Vilai J,Lyons CR

更新日期：2007-01-01 00:00:00

abstract：:Defining the pattern of lymphokine production associated with Brucella abortus is critical for advancing the development of B. abortus as a vaccine carrier. In the present study we investigated the ability of heat-inactivated B. abortus or lipopolysaccharide from B. abortus to induce lymphokine production from purifie...

journal_title：Infection and immunity

authors： Zaitseva MB,Golding H,Betts M,Yamauchi A,Bloom ET,Butler LE,Stevan L,Golding B

更新日期：1995-07-01 00:00:00

abstract：:Attachment of Fusobacterium nucleatum to various oral surfaces is mediated by several adhesins anchored on its outer surface. Monoclonal antibodies (MAbs) were prepared and used to identify the putative galactose-binding adhesin of F. nucleatum PK1594. Four unique MAbs, 8G7, 26B9, 28G11, and 29D4, were isolated on the...

journal_title：Infection and immunity

authors： Shaniztki B,Hurwitz D,Smorodinsky N,Ganeshkumar N,Weiss EI

更新日期：1997-12-01 00:00:00

abstract：:The naturally antibiotic-resistant bacterium Burkholderia pseudomallei is the causative agent of melioidosis, a disease with stubbornly high mortality and a complex, protracted treatment regimen. The worldwide incidence of melioidosis is likely grossly underreported, though it is known to be highly endemic in northern...

journal_title：Infection and immunity

authors： McMahon RM,Ireland PM,Sarovich DS,Petit G,Jenkins CH,Sarkar-Tyson M,Currie BJ,Martin JL

更新日期：2018-04-23 00:00:00

abstract：:The enterotoxin of Shigella dysenteriae I produces fluid and electrolyte secretion in the rabbit ileum. These present studies were designed to evaluate nonelectrolyte transport in rabbit ileal mucosa exposed to Shigella enterotoxin. Both 10 mM galactose and 5 mM L-alanine absorptions were significantly impaired in ent...

journal_title：Infection and immunity

authors： Binder HJ,Whiting DS

更新日期：1977-05-01 00:00:00

abstract：:Streptococcus suis serotype 2 is a porcine and human pathogen with adhesive and invasive properties. In other streptococci, large surface-associated proteins (>100 kDa) of the MSCRAMM family (microbial surface components recognizing adhesive matrix molecules) are key players in interactions with host tissue. In this s...

journal_title：Infection and immunity

authors： Baums CG,Kaim U,Fulde M,Ramachandran G,Goethe R,Valentin-Weigand P

更新日期：2006-11-01 00:00:00