当前位置： SCI文献检索 > EUROPEAN JOURNAL OF CLINICAL INVESTIGATION期刊下所有文献 > Is the pattern of solid-phase gastric emptying different between genders?

Is the pattern of solid-phase gastric emptying different between genders?

Abstract：

BACKGROUND:In the 13C-octanoate breath test, the shape of the 13CO2 excretion curve in the ascending portion reflects a pattern of gastric emptying (GE). Recent scintigraphic studies have revealed an overall delay in solid GE in fertile women compared with men. However, it remains unknown whether women have a different GE pattern compared with men. As a symptomatic delay in solid GE is specific to the female gender, it could be hypothesized that the 13CO2 excretion curve is different in shape between genders. MATERIALS AND METHODS:Because the ascending gradient of the 13CO2 excretion curve is often biphasic, the dual function of y(t) = ( a1 . tb1 + a2 . tb2) e(-K.t) was applied to fit the breath data, where a1, b1, a2, b2, and K are constants. Assessed on the 4 h-based breath samples obtained after ingestion of a 320-kcal muffin containing 100 mg 13C-octanoate, the time versus 13CO2 excretion curve was created from 31 adult volunteers (15 men and 16 women). The curve shape was characterized by the dual function, and was compared between genders. RESULTS:In both genders, the ascending gradient exhibited the biphasic feature, characterized by an initial steep rise and the subsequent blunted increase, while the descending gradient followed the monotonous decay. The initial rise was steeper and the subsequent increase was more blunted in women than in men. CONCLUSION:Women exhibit a gender-specific pattern of the 13CO2 excretion profile. A possible explanation for this gender difference is that the post-gastric feedback regulation is more potent in women than in men.

journal_name

Eur J Clin Invest

journal_title

European journal of clinical investigation

authors

Sanaka M,Yamamoto T,Anjiki H,Osaki Y,Kuyama Y

doi

10.1111/j.1365-2362.2006.01674.x

subject

Has Abstract

pub_date

2006-08-01 00:00:00

pages

574-9

issue

8

eissn

0014-2972

issn

1365-2362

pii

ECI1674

journal_volume

36

pub_type

杂志文章

相关文献

EUROPEAN JOURNAL OF CLINICAL INVESTIGATION文献大全
  • Development of bone mineral loss in insulin-treated diabetes: a 1 1/2 years follow-up study in sixty patients.

    abstract：:The change in bone mass during 1 1/2 years was determined in a longitudinal study of sixty adult insulin-treated diabetic out-patients. During the study period the mean bone mass decreased by 1.30 +/- 0.28 (SEM)% (P less than 0.001), to a mean value of 91.0 +/- 1.7% of normal (P less than 0.001). The rate of bone loss...

    journal_title：European journal of clinical investigation

    pub_type： 杂志文章

    doi：10.1111/j.1365-2362.1981.tb01765.x

    authors： McNair P,Christiansen C,Christensen MS,Madsbad S,Faber OK,Binder C,Transbøl I

    更新日期：1981-02-01 00:00:00

  • Plasmacytoid dendritic cells, a role in neoplastic prevention and progression.

    abstract：BACKGROUND:Plasmacytoid dendritic cells (pDCs) are multifunctional bone-marrow-derived immune cells that are key players in bridging the innate and adaptive immune systems. Activation of pDCs through toll-like receptor agonists has proven to be an effective treatment for some neoplastic disorders. MATERIALS AND METHOD...

    journal_title：European journal of clinical investigation

    pub_type： 杂志文章,评审

    doi：10.1111/eci.12363

    authors： Lombardi VC,Khaiboullina SF,Rizvanov AA

    更新日期：2015-01-01 00:00:00

  • A simple, rapid immunometric assay for determination of functional and growth hormone-occupied growth hormone-binding protein in human serum.

    abstract：:We present a sensitive time-resolved fluorometric immunofunctional assay (TR-FIA) for direct quantitation of functional growth hormone-binding protein (GHBP), using an immunoassay kit for growth hormone (GH-DELFIA). In addition to the immobilized GH antibody, one monoclonal antibody against GHBP was used. This anti-GH...

    journal_title：European journal of clinical investigation

    pub_type： 杂志文章

    doi：10.1046/j.1365-2362.1996.2010558.x

    authors： Fisker S,Frystyk J,Skriver L,Vestbo E,Ho KK,Orskov H

    更新日期：1996-09-01 00:00:00

  • Lipoprotein lipase and adipose tissue and plasma triglyceride clearance in patients with primary hypertriglyceridaemia.

    abstract：:1. The activity of lipoprotein lipase (E.C.3.1.1.3) extracted and released from adipose tissue has been measured in obese subjects with mild or severe hypertriglyceridaemia. The Intralipid tolerance test has been studied as a measure of in vivo clearance of exogenous triglyceride from plasma. 2. Plasma triglyceride cl...

    journal_title：European journal of clinical investigation

    pub_type： 杂志文章

    doi：10.1111/j.1365-2362.1980.tb02072.x

    authors： Taylor KG,Holdsworth G,Galton DJ

    更新日期：1980-04-01 00:00:00

  • In vivo modifications of AcSDKP metabolism and haematopoiesis in mice treated with 5-fluorouracil and Goralatide.

    abstract：BACKGROUND:The tetrapeptide acetyl-Ser-Asp-Lys-Pro (AcSDKP), a physiological inhibitor of the proliferation of haematopoietic stem cells, is degraded by the angiotensin-I-converting enzyme (ACE). Whereas synthetic AcSDKP (Goralatide) protects normal mice from the haematological toxicity of chemotherapy, it has a lower ...

    journal_title：European journal of clinical investigation

    pub_type： 杂志文章

    doi：10.1046/j.1365-2362.1998.00356.x

    authors： Comte L,Lorgeot V,Bignon J,Volkov L,Dupuis F,Wdzieczak-Bakala J,Praloran V

    更新日期：1998-10-01 00:00:00

  • Mechanisms of protein conservation during xylitol infusion after burn injury in rats: isotope kinetics and indirect calorimetry.

    abstract：:In order to study the mechanisms by which nutrients influence post-trauma metabolism, Sprague-Dawley rats received a 25% full-thickness burn and were randomly assigned to receive 12.5 g kg-1 bodyweight (BW) per day amino acids (AA) only, AA and 14.7 g hydrous glucose kg-1 BW per day or AA and 14.7 g hydrous xylitol kg...

    journal_title：European journal of clinical investigation

    pub_type： 杂志文章

    doi：10.1111/j.1365-2362.1991.tb01818.x

    authors： Georgieff M,Pscheidl E,Moldawer LL,Bistrian BR,Blackburn GL

    更新日期：1991-04-01 00:00:00

  • Patterns of co-occurrence of three single nucleotide polymorphisms of the 5,10-methylenetetrahydrofolate reductase gene in kidney transplant recipients.

    abstract：BACKGROUND:Recently, a new mutation of the 5,10-methylenetetrahydrofolate reductase (MTHFR) encoding gene was first described (1793G > A). Only few reports have studied the prevalence of this polymorphism, especially in combination with other MTHFR mutations (677C > T, 1298A > C). METHODS:We cross-sectionally identifi...

    journal_title：European journal of clinical investigation

    pub_type： 杂志文章

    doi：10.1111/j.1365-2362.2004.01394.x

    authors： Winkelmayer WC,Sunder-Plassmann G,Huber A,Födinger M

    更新日期：2004-09-01 00:00:00

  • Helicobacter pylori infection associated with high HbA1c and type 2 diabetes.

    abstract：BACKGROUND:Although the association between chronic Helicobacter pylori infection and type 2 diabetes has been suggested, findings have been inconsistent. This study evaluated the association between chronic H. pylori infection and glucose regulation. MATERIALS AND METHODS:We evaluated H. pylori infection status of pa...

    journal_title：European journal of clinical investigation

    pub_type： 杂志文章

    doi：10.1111/eci.12124

    authors： Hsieh MC,Wang SS,Hsieh YT,Kuo FC,Soon MS,Wu DC

    更新日期：2013-09-01 00:00:00

  • Novel dual inhibitors of vascular endothelial growth factor and VEGFR2 receptor.

    abstract：BACKGROUND:Vascular endothelial growth factor (VEGF) helps control tumour growth via causing new capillaries growth in tumours. Four cardiac hormones [i.e. vessel dilator, long-acting natriuretic peptide (LANP), kaliuretic peptide (KP) and atrial natriuretic peptide (ANP)] that eliminate up to up to 86% of human small-...

    journal_title：European journal of clinical investigation

    pub_type： 杂志文章

    doi：10.1111/j.1365-2362.2012.02695.x

    authors： Nguyen JP,Frost CD,Lane ML,Skelton WP IV,Skelton M,Vesely DL

    更新日期：2012-10-01 00:00:00

  • Ethanol-induced hypoglycaemia in man: its suppression by the alcohol dehydrogenase inhibitor 4-methylpyrazole.

    abstract：:Infusion of ethanol (0.6 g/kg body wt) caused marked hypoglycaemia in subjects fasted for 36 h. Previous administration of the alcohol dehydrogenase (ADH) inhibitor 4-methylpyrazole (4-MP, 7 mg/kg body wt i.v.) strongly suppressed the ethanol-induced hypoglycaemia. The rate of ethanol elimination was 84.6 mg/kg per ho...

    journal_title：European journal of clinical investigation

    pub_type： 临床试验,杂志文章

    doi：10.1111/j.1365-2362.1977.tb01640.x

    authors： Salaspuro MP,Pikkarainen P,Lindros K

    更新日期：1977-12-01 00:00:00

  • Decision shaping neutrophil-platelet interplay in inflammation: From physiology to intervention.

    abstract：:Inflammation is a well-coordinated process in response to tissue injury or infection aimed at restoration of tissue homoeostasis. Platelets and neutrophils are typically viewed important in the context of haemostasis and bacterial killing, respectively. However, as these cells are equipped with readily available armou...

    journal_title：European journal of clinical investigation

    pub_type： 杂志文章,评审

    doi：10.1111/eci.12871

    authors： Soehnlein O

    更新日期：2018-02-01 00:00:00

  • Human and porcine smooth muscle cells share similar proliferation dependence on the mevalonate pathway: implication for in vivo interventions in the porcine model.

    abstract：:Proliferation of smooth muscle cells (SMCs) plays an important role in vascular pathobiology by being involved in the development of coronary atherosclerosis and restenosis. Competitive inhibitors of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase have shown antiproliferative properties on different cell typ...

    journal_title：European journal of clinical investigation

    pub_type： 杂志文章

    doi：10.1046/j.1365-2362.1996.2550586.x

    authors： Martínez-González J,Badimon L

    更新日期：1996-11-01 00:00:00

  • Somatostatin and the immune and haematopoetic system; a review.

    abstract：:SS-R and SS have been demonstrated in non-pathological and pathological lymphoid tissue and may play a regulatory, mostly inhibitory, role in the immune response. SS is produced by lymphocytes and monocytes which suggests an autocrine or paracrine regulatory role, but SS may be released as well by nerve endings. It ca...

    journal_title：European journal of clinical investigation

    pub_type： 杂志文章,评审

    doi：10.1111/j.1365-2362.1994.tb00972.x

    authors： van Hagen PM,Krenning EP,Kwekkeboom DJ,Reubi JC,Anker-Lugtenburg PJ,Löwenberg B,Lamberts SW

    更新日期：1994-02-01 00:00:00

  • Uptake of triglyceride fatty acids in adipose tissue in vivo in man.

    abstract：:Currently available information on adipose tissue metabolism in man is mainly based on studies in vitro. In the present work adipose tissue lipid uptake was studied in vivo in man. 100 g glucose and 120 g milk fat with 10 microCi U-14C oleic acid were given in the overnight fasting state to eight women and 2 h after a...

    journal_title：European journal of clinical investigation

    pub_type： 临床试验,杂志文章,随机对照试验

    doi：10.1111/j.1365-2362.1990.tb02263.x

    authors： Mårin P,Rebuffé-Scrive M,Björntorp P

    更新日期：1990-04-01 00:00:00

  • Molecular insights into insulin action and secretion.

    abstract：:Tightly co-ordinated control of both insulin action and secretion is required in order to maintain glucose homeostasis. Gene knockout experiments have helped to define key signalling molecules that affect insulin action, including insulin and insulin-like growth factor-1 (IGF-1) receptors, insulin receptor substrate (...

    journal_title：European journal of clinical investigation

    pub_type： 杂志文章,评审

    doi：10.1046/j.1365-2362.32.s3.2.x

    authors： Rhodes CJ,White MF

    更新日期：2002-06-01 00:00:00

  • The TAXINOMISIS Project: A multidisciplinary approach for the development of a new risk stratification model for patients with asymptomatic carotid artery stenosis.

    abstract：INTRODUCTION:Asymptomatic carotid artery stenosis (ACAS) may cause future stroke and therefore patients with ACAS require best medical treatment. Patients at high risk for stroke may opt for additional revascularization (either surgery or stenting) but the future stroke risk should outweigh the risk for peri/post-opera...

    journal_title：European journal of clinical investigation

    pub_type： 杂志文章

    doi：10.1111/eci.13411

    authors： Timmerman N,Galyfos G,Sigala F,Thanopoulou K,de Borst GJ,Davidovic L,Eckstein HH,Filipovic N,Grugni R,Kallmayer M,de Kleijn DPV,Koncar I,Mantzaris MD,Marchal E,Matsagkas M,Mutavdzic P,Palombo D,Pasterkamp G,Potsika VT

    更新日期：2020-12-01 00:00:00

  • The effect of smoking on post-heparin lipoprotein and hepatic lipase, cholesteryl ester transfer protein and lecithin:cholesterol acyl transferase activities in human plasma.

    abstract：INTRODUCTION:Smoking is associated with dyslipidaemia, particularly raised plasma triglycerides and reduced high-density lipoprotein (HDL)-cholesterol and a delayed clearance of triglyceride in fat tolerance tests. The aim of this study was to investigate whether these phenomena could be explained by a reduced lipoprot...

    journal_title：European journal of clinical investigation

    pub_type： 杂志文章

    doi：10.1046/j.1365-2362.1998.00328.x

    authors： Freeman DJ,Caslake MJ,Griffin BA,Hinnie J,Tan CE,Watson TD,Packard CJ,Shepherd J

    更新日期：1998-07-01 00:00:00

  • Effect of dipyrone, acetylsalicylic acid and acetaminophen on human neutrophil chemotaxis.

    abstract：:Dipyrone metabolites 4-methylaminoantipyrine (MAA) and 4-formylaminoantipyrine (FAA) as well as acetylsalicylic acid inhibited neutrophil migration toward zymosan-activated serum. Inhibition was maximal (76.8 +/- 19.0; 79.2 +/- 12.5 and 80.0 +/- 4.4%, respectively, P less than 0.003) when suboptimal concentrations (0....

    journal_title：European journal of clinical investigation

    pub_type： 杂志文章

    doi：10.1111/j.1365-2362.1984.tb01210.x

    authors： Matzner Y,Drexler R,Levy M

    更新日期：1984-12-01 00:00:00

  • Acute insulin administration does not affect plasma leptin levels in lean or obese subjects.

    abstract：:Whether leptin levels are related to insulin sensitivity or subject to acute regulation by insulin is not known. In 12 obese [body mass index (BMI) = 34.0 +/- 1.5 kg m-2] and 12 lean (BMI = 22.2 +/- 0.6 kg m-2) non-diabetic subjects, plasma leptin concentrations were measured in the fasting state and during 2 hours of...

    journal_title：European journal of clinical investigation

    pub_type： 杂志文章

    doi：10.1111/j.1365-2362.1996.tb02142.x

    authors： Muscelli E,Camastra S,Masoni A,Baldi S,Sironi AM,Natali A,Ferrannini E

    更新日期：1996-10-01 00:00:00

  • Effect of food on antacid neutralizing capacity in man.

    abstract：:In order to estimate their in-vivo reactivity two antacids of equal theoretical neutralizing capacity (approximately 3.9 mol/l at pH 3.5) but of different chemical composition were employed as intragastric titrant (pH 3.5) following a liquid protein meal (oxo) in two groups of five volunteers each. The two antacids ch...

    journal_title：European journal of clinical investigation

    pub_type： 临床试验,杂志文章,随机对照试验

    doi：10.1111/j.1365-2362.1982.tb00995.x

    authors： Halter F,Huber R,Häcki WH,Varga L,Bachmann C

    更新日期：1982-06-01 00:00:00

  • Influence of atherosclerosis on age-related changes in renal size and function.

    abstract：BACKGROUND:Renal size and function reflect the health of the kidney. These parameters are associated with age, gender and body weight. The kidneys are also influenced by micro- and macrovascular diseases. Atherosclerotic markers and risk factors may influence the age-related changes of renal size and function. METHODS...

    journal_title：European journal of clinical investigation

    pub_type： 杂志文章

    doi：10.1046/j.1365-2362.2003.01091.x

    authors： Bax L,van der Graaf Y,Rabelink AJ,Algra A,Beutler JJ,Mali WP,SMART Study Group.

    更新日期：2003-01-01 00:00:00

  • Broad identification of bacterial type from pus by 1H MR spectroscopy.

    abstract：BACKGROUND:Abscess formation is a common bacterial infection and requires an immediate antimicrobial approach for apposite treatment. Delay in patient treatment is usually a common feature, as the bacterial identification of clinical samples is based on the culture, which is a time-consuming exercise. The current study...

    journal_title：European journal of clinical investigation

    pub_type： 杂志文章

    doi：10.1046/j.1365-2362.2003.01148.x

    authors： Garg M,Misra MK,Chawla S,Prasad KN,Roy R,Gupta RK

    更新日期：2003-06-01 00:00:00

  • Mechanism of oestrogen and progesterone effects on lipid and carbohydrate metabolism: alteration in the insulin: glucagon molar ratio and hepatic enzyme activity.

    abstract：:As in women receiving oestrogens the administration of 17beta-oestradiol to ovariectomized female rats caused a rise in fasting plasma triglycerides and a fall in plasma glucose. Progesterone, on the other hand, had no significant effects. In the oestradiol treated rats, the portal vein basal insulin levels were sligh...

    journal_title：European journal of clinical investigation

    pub_type： 杂志文章

    doi：10.1111/j.1365-2362.1977.tb01595.x

    authors： Mandour T,Kissebah AH,Wynn V

    更新日期：1977-06-01 00:00:00

  • Circulating levels of osteopontin are closely related to glomerular filtration rate and cardiovascular risk markers in patients with chronic kidney disease.

    abstract：BACKGROUND:The pleiotropic cytokine osteopontin (OPN) is thought to be involved in the pathogenesis of atherosclerosis. However, the relationship between OPN and renal function, a cardiovascular risk factor itself, is not known. Therefore, we assessed the relationship between OPN plasma levels and renal function in pat...

    journal_title：European journal of clinical investigation

    pub_type： 杂志文章

    doi：10.1111/j.1365-2362.2010.02271.x

    authors： Lorenzen J,Krämer R,Kliem V,Bode-Boeger SM,Veldink H,Haller H,Fliser D,Kielstein JT

    更新日期：2010-04-01 00:00:00

  • SOX6 rs7117858 polymorphism is associated with osteoporosis and obesity-related phenotypes.

    abstract：BACKGROUND:SOX6 has been recently proposed as a pleiotropic gene for obesity and osteoporosis. The aim of this study was to investigate whether the rs7117858 genetic variant in SOX6 was associated with bone mass assessed by quantitative ultrasound (QUS) and obesity-related measures in a population of young adults. MET...

    journal_title：European journal of clinical investigation

    pub_type： 杂志文章

    doi：10.1111/eci.13011

    authors： Correa-Rodríguez M,Schmidt-RioValle J,Rueda-Medina B

    更新日期：2018-10-01 00:00:00

  • Vascular reactivity to noradrenaline and neuropeptide Y in the streptozotocin-induced diabetic rat.

    abstract：:The study aimed to assess vascular reactivity to noradrenaline with and without neuropeptide Y in diabetic rats, and to determine whether any abnormality could be attributed to insulin deficiency or to hyperglycaemia per se. The authors compared non-diabetic rats (n = 9) and rats with streptozotocin-induced diabetes t...

    journal_title：European journal of clinical investigation

    pub_type： 杂志文章

    doi：10.1111/j.1365-2362.1995.tb01976.x

    authors： Savage MW,Bodmer CW,Walker AB,Buchan IE,Masson EA,Williams G

    更新日期：1995-12-01 00:00:00

  • Is the renal kallikrein system relevant to sodium sensitivity in patients with essential hypertension.

    abstract：:In twenty-five outpatients with essential hypertension, the relevance of renal kallikrein excretion for inter-individual differences in the blood pressure response to changes in dietary sodium intake was investigated. The patients were studied during 2 weeks of high (300 mmol) and 2 weeks of low (50-100 mmol) sodium i...

    journal_title：European journal of clinical investigation

    pub_type： 临床试验,杂志文章,随机对照试验

    doi：10.1111/j.1365-2362.1985.tb00160.x

    authors： Koolen MI,Daha MR,van Brummelen P

    更新日期：1985-06-01 00:00:00

  • Angiotensin II mediates urotensin II expression by hypoxia in cultured cardiac fibroblast.

    abstract：BACKGROUND:Urotensin II plays a role in myocardial remodelling. Cardiac fibroblasts play a critical role in the development of cardiac fibrosis. The effect of hypoxia on urotensin II expression in cardiac fibroblasts is poorly understood. We sought to investigate the regulation of urotensin II by hypoxia in cardiac fib...

    journal_title：European journal of clinical investigation

    pub_type： 杂志文章

    doi：10.1111/j.1365-2362.2011.02549.x

    authors： Shyu KG,Wang BW,Chen WJ,Kuan P,Lin CM

    更新日期：2012-01-01 00:00:00

  • Polymorphonuclear leucocyte dysregulation in patients with gram-negative septicaemia assessed by flow cytometry.

    abstract：:Flow cytometry was used to study phagocytic function and release of reactive oxygen intermediates (ROI) following phagocytosis by granulocytes in 14 patients (six female, eight male) with gram-negative septicaemia prior to, during, and after therapy compared with a group of healthy controls. Phagocytic capacity was as...

    journal_title：European journal of clinical investigation

    pub_type： 杂志文章

    doi：10.1111/j.1365-2362.1995.tb01723.x

    authors： Wenisch C,Parschalk P,Hasenhündl M,Griesmacher A,Graninger W

    更新日期：1995-06-01 00:00:00

  • Anabolic effects of rhIGF-I/IGFBP-3 in vivo are influenced by thyroid status.

    abstract：BACKGROUND:There are close interrelationships between hormones that regulate bone formation and protein biosynthesis. For example, growth hormone and thyroid hormones can influence plasma levels of insulin-like growth factor-I (IGF-I). A patient's status regarding hormones other than IGF-I may thus indirectly modify th...

    journal_title：European journal of clinical investigation

    pub_type： 临床试验,杂志文章

    doi：10.1046/j.1365-2362.2001.00793.x

    authors： Svanberg E,Healey J,Mascarenhas D

    更新日期：2001-04-01 00:00:00