Effect of food on antacid neutralizing capacity in man.

abstract：:Most physicians and other healthcare professionals are unaware of the pervasiveness of poor quality clinical evidence that contributes considerably to overuse, underuse, avoidable adverse events, missed opportunities for right care and wasted healthcare resources. The Medical Misinformation Mess comprises four key pro...

journal_title：European journal of clinical investigation

authors： Ioannidis JPA,Stuart ME,Brownlee S,Strite SA

更新日期：2017-11-01 00:00:00

abstract：:Immunoreactive parathyroid hormone (PTH) levels and nephrogenous cyclic adenosine monophosphate (cAMP) have been reported to be useful parameters in the diagnosis of hyperparathyroidism. Measurements in hyperparathyroid patients usually give values above the normal range when PTH is measured with a carboxyterminal rad...

journal_title：European journal of clinical investigation

authors： Bill G,Jacquet AF,Burckhardt P

更新日期：1984-06-01 00:00:00

abstract：BACKGROUND:Experimental and clinical studies have suggested that inhibitors of the renin angiotensin system (RAS) might be useful to slow the progression of valvular calcification in patients with aortic stenosis (AS). OBJECTIVES:The aim of this study was to evaluate the relationships between the weight and tissue rem...

journal_title：European journal of clinical investigation

authors： Côté N,Couture C,Pibarot P,Després JP,Mathieu P

更新日期：2011-11-01 00:00:00

abstract：BACKGROUND:Cardiac resynchronization therapy (CRT) is an established therapy for advanced congestive heart failure, improving both survival and hospitalization. The mechanism beneath these improvements still needs to be defined as about one-third of the patients do not benefit from resynchronization. Restoration of sym...

journal_title：European journal of clinical investigation

authors： Martignani C,Diemberger I,Nanni C,Biffi M,Ziacchi M,Boschi S,Corzani A,Fanti S,Sambuceti G,Boriani G

更新日期：2015-08-01 00:00:00

abstract：BACKGROUND:Several clinical trials have suggested that a metabolic cocktail of glucose-insulin-potassium (GIK) decreases mortality rates in patients with acute myocardial infarction (AMI). It has also been reported that Fas-mediated apoptosis plays an important role in ischaemic/reperfusion injury in the rat model. Thi...

journal_title：European journal of clinical investigation

authors： Zhang L,Zhang L,Li YH,Zhang HY,Chen ML,Gao MM,Hu AH,Yang HS,Yang HS

更新日期：2005-03-01 00:00:00

abstract：:The siblings presented here are the third family found in Japan with familial LCAT deficiency. Their post-heparin plasma lipoprotein lipase and hepatic triglyceride lipase activities were measured selectively by an immunochemical method. Plasma triglyceride levels were elevated, and post-heparin plasma lipoprotein lip...

journal_title：European journal of clinical investigation

authors： Murayama N,Asano Y,Kato K,Sakamoto Y,Hosoda S,Yamada N,Kodama T,Murase T,Akanuma Y

更新日期：1984-04-01 00:00:00

abstract：BACKGROUND:Angiotensin-converting enzyme inhibitors may affect reactive oxygen species in humans in vitro and in vivo. In the present study we evaluated whether angiotensin-converting enzyme inhibitors may affect NAD(P)H oxidase activity. MATERIALS AND METHODS:The production of reactive oxygen species was measured spe...

journal_title：European journal of clinical investigation

authors： van der Giet M,Erinola M,Zidek W,Tepel M

更新日期：2002-10-01 00:00:00

abstract：BACKGROUND:Infiltration of white adipose tissue (WAT) by inflammatory cells in obesity is considered to be a key event in the development of insulin resistance. Recently, mast cells (MCs) have been identified as new players in the pathogenesis of obesity. We aimed to investigate the relationship between MCs and various...

journal_title：European journal of clinical investigation

authors： Einwallner E,Kiefer FW,Di Caro G,Orthofer M,Witzeneder N,Hörmann G,Itariu B,Zeyda M,Penninger JM,Stulnig TM,Esterbauer H,Todoric J

更新日期：2016-11-01 00:00:00

abstract：:The work was designed to study the effects of a meat meal on glomerular filtration rate (GFR), renal plasma flow (RPF), and plasma concentrations of glucagon, insulin, growth hormone, renin, aldosterone, total amino acids, and NH3 in healthy humans (H) as well as in patients with Child A liver cirrhosis (LC). The meat...

journal_title：European journal of clinical investigation

authors： De Santo NG,Anastasio P,Loguercio C,del Vecchio Blanco C,Capasso G,Coppola S,Bellini L,Spagnuolo G,Federico P,Alfieri R

更新日期：1992-01-01 00:00:00

abstract：BACKGROUND:Blocking the renin-angiotensin system (RAS) with angiotensin receptor blockers or angiotensin-converting enzyme inhibitors protects against renal injury in patients with chronic kidney disease (CKD). The aim of this study was to compare the chronic effects of telmisartan and enalapril on proteinuria, urinary...

journal_title：European journal of clinical investigation

authors： Nakamura T,Fujiwara N,Kawagoe Y,Sugaya T,Ueda Y,Koide H

更新日期：2010-09-01 00:00:00

abstract：:Ten men with Klinefelter's syndrome were studied to assess the effect of testosterone replacement on plasma lipids and apolipoproteins. Measurements taken before the insertion of a testosterone ester implant were compared with those obtained 1 week and 4 weeks later. Mean plasma testosterone, androstenedione, total ch...

journal_title：European journal of clinical investigation

authors： Jones DB,Higgins B,Billet JS,Price WH,Edwards CR,Beastall GH,Shepherd J,Sweeting VM,Horn DB,Wenham PR

更新日期：1989-10-01 00:00:00

abstract：BACKGROUND:Glucocorticosteroids are effective in the treatment of allergic rhinitis, a disease characterized by a variety of symptoms, e.g. rhinorrhea and itching. The time course of symptomatic relief for allergic rhinitis by steroids has not been examined in detail to date, although the onset of steroid action is one...

journal_title：European journal of clinical investigation

authors： Tillmann HC,Stuck BA,Feuring M,Rossol-Haseroth K,Tran BM,Lösel R,Schmidt BM,Hörmann K,Wehling M,Schultz A

更新日期：2004-01-01 00:00:00

abstract：:Obesity is a multifactorial disease with a marked genetic component. The situation is further complicated by the heterogeneity of obesity demonstrated by the topographical distribution of body fat, e.g. upper body (central) and lower body (gluteal) obesity. Furthermore, the distribution of fat shows a stronger heritab...

journal_title：European journal of clinical investigation

authors： Weaver JU,Kopelman PG,Hitman GA

更新日期：1992-04-01 00:00:00

abstract：:The ATP-binding cassette transporter P-glycoprotein is now recognized as an important determinant for disposition of multiple drugs. The use of P-glycoprotein-expressing cell lines, the generation of P-glycoprotein knockout mice as well as studies in animals and humans contributed to a better understanding on the role...

journal_title：European journal of clinical investigation

authors： Fromm MF

更新日期：2003-11-01 00:00:00

abstract：:The metabolic responses to 4-h infusions of adrenaline (3 micrograms kg-1 h-1) and cortisol (10 mg m-2 h-1 for 2 h followed by 5 mg m-2 h-1 for 2 h), separately and in combination, have been studied in six healthy subjects with concurrent somatostatin infusion (250 micrograms h-1). A combined infusion of adrenaline, c...

journal_title：European journal of clinical investigation

authors： Pernet A,Johnston DG,Hammond V,Orskov H,Alberti KG

更新日期：1986-08-01 00:00:00

abstract：:In twenty-five outpatients with essential hypertension, the relevance of renal kallikrein excretion for inter-individual differences in the blood pressure response to changes in dietary sodium intake was investigated. The patients were studied during 2 weeks of high (300 mmol) and 2 weeks of low (50-100 mmol) sodium i...

journal_title：European journal of clinical investigation

authors： Koolen MI,Daha MR,van Brummelen P

更新日期：1985-06-01 00:00:00

abstract：BACKGROUND:Several studies have reported a significant gender difference in low-density lipoprotein (LDL) size, with men being characterized by smaller, denser LDL particles than women, and it has been suggested that the contribution of the greater accumulation of visceral adipose tissue in men compared with women may ...

journal_title：European journal of clinical investigation

authors： Lemieux I,Pascot A,Lamarche B,Prud'homme D,Nadeau A,Bergeron J,Després JP

更新日期：2002-12-01 00:00:00

abstract：:Skeletal muscle glycogen deposition, and the activation of muscle glycogen synthase and pyruvate dehydrogenase during a hyerinsulinaemic euglycaemic clamp have been measured in six young and six elderly males matched for body mass index, physical activity and diet. Clamp glucose requirement (insulin, 0.1 U kg-1 h-1) w...

journal_title：European journal of clinical investigation

authors： Kruszynska YT,Petranyi G,Alberti KG

更新日期：1988-10-01 00:00:00

abstract：BACKGROUND:Vitamin E supplementation is associated with a reduced risk of developing atherosclerotic events; probably because it inhibits low-density lipoprotein (LDL) oxidation, an initial step in atherosclerosis. Metal ion-dependent LDL oxidation is a commonly used method to estimate oxidizability of LDL, but the eff...

journal_title：European journal of clinical investigation

authors： Wen Y,Killalea S,Norris LA,Cooke T,Feely J

更新日期：1999-12-01 00:00:00

abstract：:The retardation of gastric emptying induced by infusion of triglyceride into the small intestine is associated with suppression of antral pressure waves and stimulation of basal pyloric tone in combination with phasic pressure waves localized to the pylorus. The role of nitric oxide (NO) mechanisms in the control of p...

journal_title：European journal of clinical investigation

authors： Sun WM,Doran S,Lingenfelser T,Hebbard GS,Morley JE,Dent J,Horowitz M

更新日期：1996-08-01 00:00:00

abstract：BACKGROUND:Mortality from prostate cancer remains a significant problem with current treatment(s), with an expected 30 350 deaths from prostate cancer in 2005. Long-acting natriuretic peptide, vessel dilator, kaliuretic peptide and atrial natriuretic peptide have significant anticancer effects in breast and pancreatic ...

journal_title：European journal of clinical investigation

authors： Vesely BA,Alli AA,Song SJ,Gower WR Jr,Sanchez-Ramos J,Vesely DL

更新日期：2005-11-01 00:00:00

abstract：:To study the effect of glucagon immunoneutralization on postoperative changes of urea synthesis, hysterectomized rats were given one injection of a specific high titre antibody against pancreatic glucagon 24 h before operation raising the plasma glucagon binding capacity to values 10-20 times higher than the plasma gl...

journal_title：European journal of clinical investigation

authors： Heindorff H,Holst JJ,Almdal T,Vilstrup H

更新日期：1993-03-01 00:00:00

abstract：:• The rapid and continuing progress in gene discovery for complex diseases is fuelling interest in the potential application of genetic risk models for clinical and public health practice. • The number of studies assessing the predictive ability is steadily increasing, but they vary widely in completeness of reporting...

journal_title：European journal of clinical investigation

authors： Janssens AC,Ioannidis JP,Bedrosian S,Boffetta P,Dolan SM,Dowling N,Fortier I,Freedman AN,Grimshaw JM,Gulcher J,Gwinn M,Hlatky MA,Janes H,Kraft P,Melillo S,O'Donnell CJ,Pencina MJ,Ransohoff D,Schully SD,Seminara D,

更新日期：2011-09-01 00:00:00

abstract：:In nine patients with non-malignant diseases undergoing major upper abdominal surgery, the mechanism of the postoperative fibrinolytic shut-down was investigated because of its potential significance for postoperative deep vein thrombosis by employing new and specific methods for assessing and stimulating the fibrinol...

journal_title：European journal of clinical investigation

authors： D'Angelo A,Kluft C,Verheijen JH,Rijken DC,Mozzi E,Mannucci PM

更新日期：1985-12-01 00:00:00

abstract：BACKGROUND:Changes in plasma leptin concentration and food intake occur during the menstrual cycle; because leptin regulates food intake, one could hypothesize that changes in plasma leptin concentration and in food intake are associated throughout the menstrual cycle. However, no data have ever been provided to suppor...

journal_title：European journal of clinical investigation

authors： Paolisso G,Rizzo MR,Mazziotti G,Rotondi M,Tagliamonte MR,Varricchio G,Carella C,Varricchio M

更新日期：1999-06-01 00:00:00

abstract：:Currently available information on adipose tissue metabolism in man is mainly based on studies in vitro. In the present work adipose tissue lipid uptake was studied in vivo in man. 100 g glucose and 120 g milk fat with 10 microCi U-14C oleic acid were given in the overnight fasting state to eight women and 2 h after a...

journal_title：European journal of clinical investigation

authors： Mårin P,Rebuffé-Scrive M,Björntorp P

更新日期：1990-04-01 00:00:00

abstract：BACKGROUND:Hepatocytes are polarized epithelial cells with three morphologically and functionally distinct membrane surfaces: the sinusoidal, lateral and canalicular surface domains. These domains differ from each other in the expression of integral proteins, which concur to their polarized functions. We hypothesize th...

journal_title：European journal of clinical investigation

authors： Liquori GE,Mastrodonato M,Rossi R,Scillitani G,Gena P,Portincasa P,Calamita G,Ferri D

更新日期：2010-05-01 00:00:00

abstract：BACKGROUND:In Western societies colonic cancer most frequently develops in the distal colon, largely as a result of the composition of the diet. Modulation of dietary factors is therefore an attractive modality to reduce colorectal cancer risk. This study aims to evaluate the potentially protective effects of calcium i...

journal_title：European journal of clinical investigation

authors： van Gorkom BA,van der Meer R,Karrenbeld A,van der Sluis T,Zwart N,Termont DS,Boersma-van Ek W,de Vries EG,Kleibeuker JH

更新日期：2002-09-01 00:00:00

abstract：:The effect of the potent specific cholecystokinin (CCK) receptor antagonist loxiglumide on meal-stimulated plasma concentrations of CCK, gastrin, pancreatic polypeptide (PP), neurotensin, glucose-dependent insulinotropic polypeptide (GIP), insulin and C peptide was investigated in a placebo-controlled study in 10 heal...

journal_title：European journal of clinical investigation

authors： Schmidt WE,Creutzfeldt W,Höcker M,Nustede R,Choudhury AR,Schleser A,Rovati LC,Fölsch UR

更新日期：1991-10-01 00:00:00

abstract：:Approximately 20% of monocytes and peritoneal macrophages from renal failure patients undergoing continuous ambulatory peritoneal dialysis (CAPD) were transferrin-receptor (TfR) positive by immunofluorescence, whereas cells from normal controls were generally TfR negative, as were monocytes from rheumatoid arthritis p...

journal_title：European journal of clinical investigation

authors： Moughal NA,McGregor SJ,Brock JH,Briggs JD,Junor BJ

更新日期：1991-12-01 00:00:00