Influence of atherosclerosis on age-related changes in renal size and function.

abstract：BACKGROUND:Increasing evidence indicates that nonalcoholic fatty liver disease (NAFLD) is linked to an increased risk of extra-hepatic conditions. However, it is currently uncertain whether NAFLD is associated with the risk of gastroesophageal reflux disease (GERD). We performed a systematic review and meta-analysis of...

journal_title：European journal of clinical investigation

authors： Xue J,Xin H,Ren N,Zhou C,Yang J,Song L,Qin S

更新日期：2019-09-01 00:00:00

abstract：BACKGROUND:Although both strength training (ST) and endurance training (ET) seem to be beneficial in type 2 diabetes mellitus (T2D), little is known about post-exercise glucose profiles. The objective of the study was to report changes in blood glucose (BG) values after a 4-month ET and ST programme now that a device f...

journal_title：European journal of clinical investigation

authors： Cauza E,Hanusch-Enserer U,Strasser B,Kostner K,Dunky A,Haber P

更新日期：2005-12-01 00:00:00

abstract：BACKGROUND:We investigated whether plasma ferritin levels through the pro-inflammatory effects of free iron are associated with adipose tissue dysfunction in a relevant population of patients with manifest vascular disease who would potentially benefit the most from further aetiological insights. MATERIALS AND METHODS...

journal_title：European journal of clinical investigation

authors： Westerink J,Olijhoek JK,Koppen A,Faber DR,Kalkhoven E,Monajemi H,van Asbeck BS,van der Graaf Y,Visseren FL

更新日期：2013-12-01 00:00:00

abstract：BACKGROUND:Patients with continuous ambulatory peritoneal dialysis (CAPD) have high all-cause mortality risk that varies extensively among different conditions. The objective of this study was to develop and validate risk models to predict the 2-year all-cause mortality risks of CAPD patients. MATERIAL AND METHODS:A t...

journal_title：European journal of clinical investigation

authors： Zhao C,Luo Q,Xia X,He F,Peng F,Yu X,Huang F

更新日期：2014-11-01 00:00:00

abstract：BACKGROUND:Childhood obesity is associated with premature cardiovascular complications. However, little is known about the effect of a family-based behavioural intervention on the relationship between arterial function, blood pressure and biomarkers in pre-pubertal children with obesity. DESIGN:This was a single centr...

journal_title：European journal of clinical investigation

authors： Maggio ABR,Farpour-Lambert NJ,Aggoun Y,Galan K,Montecucco F,Mach F,Beghetti M

更新日期：2018-09-01 00:00:00

abstract：BACKGROUND:Diverticular disease (DD) and irritable bowel syndrome (IBS) share a similar symptom pattern. However, comparative studies are flawed by different age at onset of symptoms. We aimed to verify whether clinical features distinguish DD from IBS. MATERIALS AND METHODS:Patients with DD or IBS, matched for age an...

journal_title：European journal of clinical investigation

authors： Cuomo R,Barbara G,Andreozzi P,Bassotti G,Casetti T,Grassini M,Ierardi E,Maconi G,Marchi S,Sarnelli G,Savarino V,Usai P,Vozzella L,Annibale B

更新日期：2013-11-01 00:00:00

abstract：:The stimulant action of branched-chain amino acids upon insulin release was examined in rat pancreatic islets incubated at physiological concentrations of D-glucose and L-glutamine. In the presence of the latter nutrients, L-leucine and L-isoleucine used together at a physiological concentration (0.25 mmol/l each) dou...

journal_title：European journal of clinical investigation

authors： Sener A,Malaisse WJ

更新日期：1981-12-01 00:00:00

abstract：:There is considerable information to indicate that when there is vessel injury, platelets can play a major role in the development of atherosclerosis and its thromboembolic complications in the non-diabetic population. Diabetes is a disease associated with an increased risk of vascular complications, but the nature of...

journal_title：European journal of clinical investigation

authors： Winocour PD

更新日期：1994-02-01 00:00:00

abstract：:To diagnose hypolactasia, determination of lactase enzyme activity in small intestinal biopsy material is considered to be the golden standard. Because of its strongly invasive character and the sampling problems, alternative methods have been looked for. We analysed the 13C-glucose response in serum after consumption...

journal_title：European journal of clinical investigation

authors： Vonk RJ,Stellaard F,Priebe MG,Koetse HA,Hagedoorn RE,De Bruijn S,Elzinga H,Lenoir-Wijnkoop I,Antoine JM

更新日期：2001-03-01 00:00:00

abstract：:Alpha-naphthyl-isothiocyanate (ANIT)-induced intrahepatic cholangitis was associated with significant polyuria in rats. The urine output in the experimental rats was about two and a half to four fold higher than that in the controls. The polyuria was accompanied by polydypsia and disappeared when water intake was limi...

journal_title：European journal of clinical investigation

authors： Tur-Kaspa R,Adler R,Popovtzer MM,Eliakim M

更新日期：1983-02-01 00:00:00

abstract：:The impact of running and menstrual disturbances on regional and total body fat distribution and serum lipids was investigated in 205 women. Body composition was measured by dual-energy X-ray absorptiometry. The total fat mass in the elite runners was approximately half of the normally active's (7.3 [0.48] kg vs. 14.3...

journal_title：European journal of clinical investigation

authors： Hetland ML,Haarbo J,Christiansen C

更新日期：1995-08-01 00:00:00

abstract：BACKGROUND:Inflammation and immune activation appear to be important in the pathogenesis of coronary heart disease (CHD). Cytokine interferon-gamma, which is released during cell-mediated immune responses, induces indoleamine (2,3)-dioxygenase (IDO), an enzyme degrading tryptophan to kynurenine. Therefore, immune stimu...

journal_title：European journal of clinical investigation

authors： Wirleitner B,Rudzite V,Neurauter G,Murr C,Kalnins U,Erglis A,Trusinskis K,Fuchs D

更新日期：2003-07-01 00:00:00

abstract：:Eur J Clin Invest 2012; 42 (6): 579-588 ABSTRACT: Glucose-based methods are currently gold standards for identifying individuals at risk of type 2 diabetes. Obviously, these methods only consider one of many pathologies of impaired glucose metabolism and they all suffer from a poor specificity as type 2 diabetes risk ...

journal_title：European journal of clinical investigation

authors： Gjesing AP,Pedersen O

更新日期：2012-06-01 00:00:00

abstract：BACKGROUND:Arterial stiffness is an important determinant of cardiovascular risk. It is associated with several cardiovascular risk factors, including hypertension, diabetes and cigarette smoking. However, there are conflicting data about the relationship between arterial stiffness and hypercholesterolemia. Furthermore...

journal_title：European journal of clinical investigation

authors： Riggio S,Mandraffino G,Sardo MA,Iudicello R,Camarda N,Imbalzano E,Alibrandi A,Saitta C,Carerj S,Arrigo T,Saitta A

更新日期：2010-03-01 00:00:00

abstract：BACKGROUND:In obese subjects, chronic low-grade inflammation contributes to an increased risk of metabolic abnormalities, which are reversed by weight loss. Sustained weight loss, however, is difficult to achieve and more insight into dietary approaches on anti-inflammatory responses in obese subjects is needed. In thi...

journal_title：European journal of clinical investigation

authors： Jellema A,Plat J,Mensink RP

更新日期：2004-11-01 00:00:00

abstract：BACKGROUND:Acute ischaemic stroke (AIS) triggers both systemic and neurovascular inflammation, influencing poststroke recovery. In smokers with AIS, inflammation might be further upregulated, increasing ischaemia/reperfusion injury. Here, the predictive value of leucocyte and adhesion molecules levels on poststroke out...

journal_title：European journal of clinical investigation

authors： Liberale L,Montecucco F,Bonaventura A,Casetta I,Seraceni S,Trentini A,Padroni M,Dallegri F,Fainardi E,Carbone F

更新日期：2017-10-01 00:00:00

abstract：:The secretion of insulin and glucagon was investigated in pancreatic islets from diabetic and nondiabetic sand rats of similar age and weight. The metabolic characterization was based on an intraperitoneal glucose tolerance test. Compared to nondiabetic animals diabetic sand rats had a diminished insulin content in th...

journal_title：European journal of clinical investigation

authors： Hahn HJ,Schäfer H,Gottschling HD,Fiedler H

更新日期：1976-01-30 00:00:00

abstract：BACKGROUND:The pathogenesis of tumour formation in the anterior pituitary including adrenocorticotropic hormone (ACTH)-secreting tumours has been intensively studied, but the causative mechanisms involved in pituitary cell transformation and tumourigenesis remain unclear. MATERIALS AND METHODS:We searched PubMed on an...

journal_title：European journal of clinical investigation

authors： Dworakowska D,Grossman AB

更新日期：2012-06-01 00:00:00

abstract：BACKGROUND AND AIMS:Diabetes dramatically increases the risk of cardiovascular complications and mortality. Hydrogen sulphide plays an important role in reducing oxidative stress. Several studies demonstrated that hydrogen sulphide protects islet beta cells from oxidant stress damage and decreases apoptosis. The aim of...

journal_title：European journal of clinical investigation

authors： Dorofeyeva N,Drachuk K,Rajkumar R,Sabnis O,Sagach V

更新日期：2021-01-01 00:00:00

abstract：BACKGROUND:Circulatory dysfunction in portal hypertension is characterized by increased cardiac output, decreased systemic vascular resistance, a fall in mean arterial pressure secondary to splanchnic and systemic vasodilation and hence renal hypoperfusion. Previous studies have disclosed that renal vasculatures of por...

journal_title：European journal of clinical investigation

authors： Chuang CL,Huang HC,Chang CC,Lee FY,Wu JC,Lee SD

更新日期：2013-03-01 00:00:00

abstract：BACKGROUND:Metastatic pheochromocytomas (PCs) and paragangliomas (PGLs) are rare neuroendocrine tumours with a strong genetic background. DESIGN:We searched the PubMed database through February 2015 to identify studies characterizing metastatic PCs/PGLs as well as currently established and evolving therapies. RESULTS...

journal_title：European journal of clinical investigation

authors： Angelousi A,Kassi E,Zografos G,Kaltsas G

更新日期：2015-09-01 00:00:00

abstract：BACKGROUND:Early menopause, whether it be natural or surgical, is one of the established risk factors for osteoporosis. Surgical menopause, however, differs from natural menopause owing to the abrupt cessation of estrogen secretion. This study attempts to investigate the influence of menopause type on bone mineral dens...

journal_title：European journal of clinical investigation

authors： Hadjidakis D,Kokkinakis E,Sfakianakis M,Raptis SA

更新日期：1999-10-01 00:00:00

abstract：BACKGROUND:Obstructive sleep apnoea (OSA) is a common complication of obesity and can have a substantial negative impact on a patient's quality of life and risk of cardiovascular disease. The aim of this case-control study was to undertake discovery profiling of urinary peptides using capillary electrophoresis-mass spe...

journal_title：European journal of clinical investigation

authors： Seetho IW,Siwy J,Albalat A,Mullen W,Mischak H,Parker RJ,Craig S,Duffy N,Hardy KJ,Burniston JG,Wilding JP

更新日期：2014-11-01 00:00:00

abstract：:The aim of the present study was to investigate possible relationships in piglets between myocardial energy-related metabolites and intracellular electrolytes during open-chest cardiopulmonary resuscitation (OCCPR) supplemented by the administration of alkaline buffers with varying sodium content. Our hypothesis was t...

journal_title：European journal of clinical investigation

authors： Wiklund L,Ronquist G,Roomans GM,Rubertsson S,Waldenström A

更新日期：1997-05-01 00:00:00

abstract：:Portal-systemic spill-over of unconjugated ursodeoxycholic acid (UDCA) was assessed in ten healthy subjects, six patients with mild chronic liver disease and eight patients with cirrhosis. Following oral administration of UDCA (1.5 mg/kg body weight), serum concentrations of unconjugated UDCA were measured during 2 h ...

journal_title：European journal of clinical investigation

authors： Miescher G,Paumgartner G,Preisig R

更新日期：1983-12-01 00:00:00

abstract：BACKGROUND:Experimental and clinical studies have suggested that inhibitors of the renin angiotensin system (RAS) might be useful to slow the progression of valvular calcification in patients with aortic stenosis (AS). OBJECTIVES:The aim of this study was to evaluate the relationships between the weight and tissue rem...

journal_title：European journal of clinical investigation

authors： Côté N,Couture C,Pibarot P,Després JP,Mathieu P

更新日期：2011-11-01 00:00:00

abstract：:The purpose of this work was to examine in an open, randomized parallel-group study whether an intervention programme directed towards hypercholesterolaemia, smoking and diabetes mellitus in treated hypertensive men was associated with less complex formation between low-density lipoprotein (LDL) and human arterial pro...

journal_title：European journal of clinical investigation

authors： Fagerberg B,Wiklund O,Agewall S,Camejo G,Wikstrand RJ

更新日期：1996-11-01 00:00:00

abstract：:Hyperthyroidism is associated with an increase in both osteoblast and osteoclast activity. We have previously shown that, in vitro, osteoclasts do not respond directly to tri-iodothyronine to increase bone resorption but that the effect is mediated by another bone cell, probably the osteoblast. To investigate this iss...

journal_title：European journal of clinical investigation

authors： Allain TJ,Yen PM,Flanagan AM,McGregor AM

更新日期：1996-05-01 00:00:00

abstract：BACKGROUND:Chronic portal hypertension is associated with the development of portal-systemic collaterals. Long-term octreotide treatment has been shown to enhance the constrictive response to vasopressin in the mesenteric arteries of portal hypertensive rats. This study investigated the effects of long-term octreotide ...

journal_title：European journal of clinical investigation

authors： Wang SS,Chan CC,Lee FY,Chang FY,Lin HC,Chen CT,Huang HC,Tai CC,Lai IN,Lee SD

更新日期：2002-05-01 00:00:00

abstract：BACKGROUND:We recently reported high high-density lipoprotein (HDL) cholesterol as a predictor of recurrent risk in a subgroup of postinfarction patients defined by hypercholesterolemia and high C-reactive protein (CRP) levels. We investigated whether a similar high-risk subgroup might exist for incident cardiovascular...

journal_title：European journal of clinical investigation

authors： Corsetti JP,Gansevoort RT,Sparks CE,Dullaart RP

更新日期：2010-06-01 00:00:00