The isoform-specific expression of the tri-iodothyronine receptor in osteoblasts and osteoclasts.

abstract：BACKGROUND:Several studies have reported a significant gender difference in low-density lipoprotein (LDL) size, with men being characterized by smaller, denser LDL particles than women, and it has been suggested that the contribution of the greater accumulation of visceral adipose tissue in men compared with women may ...

journal_title：European journal of clinical investigation

authors： Lemieux I,Pascot A,Lamarche B,Prud'homme D,Nadeau A,Bergeron J,Després JP

更新日期：2002-12-01 00:00:00

abstract：BACKGROUND:Differences in lipid parameters between patients with acute coronary syndromes (ACS) and patients with stable coronary artery disease (CAD) are unclear and are addressed in this study. METHODS:We enrolled 582 patients with angiographically proven stable CAD (of whom 26·9% had diabetes mellitus type 2 (T2DM)...

journal_title：European journal of clinical investigation

authors： Vonbank A,Saely CH,Rein P,Drexel H

更新日期：2015-10-01 00:00:00

abstract：:Investigations were carried out to analyse the interactions of alpha 2-antagonists (yohimbine, idazoxan, SK & F-86,466) with human fat cell alpha 2-adrenoceptors. All the alpha 2-antagonists enhanced the lipolytic potencies of epinephrine with an order of potency: yohimbine greater than idazoxan greater than SK & F-86...

journal_title：European journal of clinical investigation

authors： Galitzky J,Taouis M,Berlan M,Rivière D,Garrigues M,Lafontan M

更新日期：1988-12-01 00:00:00

abstract：:The possible association between lipoprotein(a) [Lp(a)] and albumin excretion rate (AER) is a topic that generates conflicting views. In addition, Lp(a) phenotypes have not previously been considered as factors influencing AER. In order to clarify this issue, we studied 70 non-insulin-dependent diabetes mellitus (NIDD...

journal_title：European journal of clinical investigation

authors： Hernández C,Simó R,Chacón P,Segarra A,López D,Mesa J

更新日期：1997-06-01 00:00:00

abstract：BACKGROUND:Bone marrow (BM) histology/immunohistochemistry, KIT D816V mutation analysis and serum tryptase measurements are mandatory tools for diagnosis of systemic mastocytosis (SM). MATERIALS AND METHODS:Within the 'German Registry of Disorders on Eosinophils and Mast Cells', we identified 65 patients with SM who h...

journal_title：European journal of clinical investigation

authors： Jawhar M,Schwaab J,Horny HP,Sotlar K,Naumann N,Fabarius A,Valent P,Cross NC,Hofmann WK,Metzgeroth G,Reiter A

更新日期：2016-05-01 00:00:00

abstract：:The esterolytic activity of mixed and parotid saliva in cystic fibrosis (CF) patients and normal subjects was determined using BAEE (alpha-Benzoyl-1-arginine-ethylester) as the substrate. Using soybean-trypsin-inhibitor the trypsin-like activity (TLA) was measured and plotted as a function of parotid flow rate. In add...

journal_title：European journal of clinical investigation

authors： Schöni M,Kaiser D,Drack E,Axmacher U

更新日期：1975-04-01 00:00:00

abstract：:The effects of dazoxiben on finger-blood flow in response to cold challenge were studied in normal subjects and patients with Raynaud's phenomenon. In normal subjects concentrations of TXB2 and 6-oxo-PGF1 alpha were measured in blood taken from dorsal hand veins following cold challenge. In a parallel multicentre stud...

journal_title：European journal of clinical investigation

authors： Tindall H,Tooke JE,Menys VC,Martin MF,Davies JA

更新日期：1985-02-01 00:00:00

abstract：:In systemic lupus erythematosus (SLE) patients, most of the clinical manifestation share a vascular component triggered by endothelial dysfunction. Endothelial cells (ECs) activation occurs both on the arterial and venous side, and the high vascular density of kidneys accounts for the detrimental outcomes of SLE throu...

journal_title：European journal of clinical investigation

authors： Mancardi D,Arrigo E,Cozzi M,Cecchi I,Radin M,Fenoglio R,Roccatello D,Sciascia S

更新日期：2021-02-01 00:00:00

abstract：:Increased activity of the Na+/H+ antiport may be a major abnormality in essential hypertension. The activity of this transport system was investigated in lymphocytes from 13 patients with untreated essential hypertension (Ht) and 13 normotensive control subjects (Nt) on an ad libitum (130-170 mmol d-1) NaCl intake. Fu...

journal_title：European journal of clinical investigation

authors： Göbel BO,Hoffmann G,Ruppert M,Stumpe KO,Vetter H,Siffert W,Düsing R

更新日期：1994-08-01 00:00:00

abstract：BACKGROUND:Mortality from prostate cancer remains a significant problem with current treatment(s), with an expected 30 350 deaths from prostate cancer in 2005. Long-acting natriuretic peptide, vessel dilator, kaliuretic peptide and atrial natriuretic peptide have significant anticancer effects in breast and pancreatic ...

journal_title：European journal of clinical investigation

authors： Vesely BA,Alli AA,Song SJ,Gower WR Jr,Sanchez-Ramos J,Vesely DL

更新日期：2005-11-01 00:00:00

abstract：BACKGROUND:Interleukin 18(IL-18) is a pro-atherosclerotic cytokine. Elevated IL-18 levels and the genetic variation of the IL-18 have been previously linked with acute coronary events and cardiovascular mortality among patients with coronary artery disease (CAD). We studied the possible association between the IL-18 ge...

journal_title：European journal of clinical investigation

authors： Hernesniemi JA,Anttila K,Nieminen T,Kähönen M,Mononen N,Nikus K,Turjanmaa V,Viik J,Lehtinen R,Lehtimäki T

更新日期：2010-11-01 00:00:00

abstract：BACKGROUND:Memory and cognitive functions are known to decline with advancing age. Studies have suggested that this may be due to a decrease in cholinergic function in the brains of elderly people. This review aims to assess studies documented in the literature dealing with the 'scopolamine model' of dementia. METHODS...

journal_title：European journal of clinical investigation

authors： Ebert U,Kirch W

更新日期：1998-11-01 00:00:00

abstract：BACKGROUND:Abscess formation is a common bacterial infection and requires an immediate antimicrobial approach for apposite treatment. Delay in patient treatment is usually a common feature, as the bacterial identification of clinical samples is based on the culture, which is a time-consuming exercise. The current study...

journal_title：European journal of clinical investigation

authors： Garg M,Misra MK,Chawla S,Prasad KN,Roy R,Gupta RK

更新日期：2003-06-01 00:00:00

abstract：BACKGROUND:The oral dual endothelin (ET) antagonist bosentan has been established as a cornerstone in the treatment of pulmonary arterial hypertension (PAH). ET is believed to be a key pathogenic mediator in systemic sclerosis (scleroderma, SSc), causing fibrotic, hypertrophic and inflammatory processes. PAH is one of ...

journal_title：European journal of clinical investigation

authors： Ahmadi-Simab K,Hellmich B,Gross WL

更新日期：2006-09-01 00:00:00

abstract：BACKGROUND:Reduced aortic distensibility predicts cardiovascular mortality in patients with type 2 diabetes and impaired glucose tolerance. Cardiac autonomic neuropathy is common in subjects with diabetes. However, the relationship between the elastic properties of the aorta and autonomic neuropathy has not been studie...

journal_title：European journal of clinical investigation

authors： Tentolouris N,Liatis S,Moyssakis I,Tsapogas P,Psallas M,Diakoumopoulou E,Voteas V,Katsilambros N

更新日期：2003-12-01 00:00:00

abstract：BACKGROUND:High levels of circulating cell-free DNA (cfDNA) have been reported in patients with inflammatory conditions. The aim of the study was to investigate the levels of cfDNA in patients with systemic lupus erythematosus (SLE). MATERIALS AND METHODS:Comparative groups comprised 22 nonpregnant and 36 pregnant wom...

journal_title：European journal of clinical investigation

authors： Xu Y,Song Y,Chang J,Zhou X,Qi Q,Tian X,Li M,Zeng X,Xu M,Zhang W,Cram DS,Liu J

更新日期：2018-11-01 00:00:00

abstract：OBJECTIVE:To evaluate comprehensively the effects of 12 prophylaxis interventions for secondary prophylaxis of variceal bleeding using multiple-treatments meta-analysis. METHODS:PubMed, EMBASE and the Cochrane Library were searched prior to November 2011. Randomized controlled trials (RCTs) comparing the interventions...

journal_title：European journal of clinical investigation

authors： Shi KQ,Liu WY,Pan ZZ,Ling XF,Chen SL,Chen YP,Fan YC,Zheng MH

更新日期：2013-08-01 00:00:00

abstract：:1. The activity of lipoprotein lipase (E.C.3.1.1.3) extracted and released from adipose tissue has been measured in obese subjects with mild or severe hypertriglyceridaemia. The Intralipid tolerance test has been studied as a measure of in vivo clearance of exogenous triglyceride from plasma. 2. Plasma triglyceride cl...

journal_title：European journal of clinical investigation

authors： Taylor KG,Holdsworth G,Galton DJ

更新日期：1980-04-01 00:00:00

abstract：BACKGROUND:Bleeding time has been reported to increase during gaseous nitric oxide (NO) inhalation in healthy volunteers and patients, and it has been speculated that inhaled NO inhibits platelet function. However, results have not been unanimous, and we have been unable to document any effects of inhaled NO on circula...

journal_title：European journal of clinical investigation

authors： Albert J,Norman M,Wallén NH,Frostell C,Hjemdahl P

更新日期：1999-11-01 00:00:00

abstract：BACKGROUND:Graves' disease (GD) is an autoimmune disorder characterized by hyperthyroidism, which can relapse in many patients after antithyroid drug treatment withdrawal. Several studies have been performed to predict the clinical course of GD in patients treated with antithyroid drugs, without conclusive results. The...

journal_title：European journal of clinical investigation

authors： Orunesu E,Bagnasco M,Salmaso C,Altrinetti V,Bernasconi D,Del Monte P,Pesce G,Marugo M,Mela GS

更新日期：2004-03-01 00:00:00

abstract：BACKGROUND:Bezafibrate reportedly lowers serum lipids and plasma fibrinogen in humans and rats, but the mechanism of this process has still to be clarified. We have addressed this problem by investigating the effects of bezafibrate on fibrinogen in the human hepatoma HepG2 cell line. METHODS:In cells cultured with and...

journal_title：European journal of clinical investigation

authors： Binsack R,Stegmeier K,Dörge L,Völkl A

更新日期：1998-02-01 00:00:00

abstract：:The electrical parameters and the unidirectional fluxes of 45Ca and 3H-mannitol were measured in preparations of rat colon descendens freed from the muscularis externa and mounted in a modified Ussing-chamber. Two criteria were used to differentiate between changes in the trans- and the paracellular calcium transport ...

journal_title：European journal of clinical investigation

authors： Karbach U,Rummel W

更新日期：1986-10-01 00:00:00

abstract：:Obesity is a multifactorial disease with a marked genetic component. The situation is further complicated by the heterogeneity of obesity demonstrated by the topographical distribution of body fat, e.g. upper body (central) and lower body (gluteal) obesity. Furthermore, the distribution of fat shows a stronger heritab...

journal_title：European journal of clinical investigation

authors： Weaver JU,Kopelman PG,Hitman GA

更新日期：1992-04-01 00:00:00

abstract：:We have reported that the disorder of lipoprotein metabolism in hyperalphalipoproteinaemic patients with a deficiency of cholesteryl ester transfer protein (CETP) is characterized by the polydisperse low density lipoprotein (LDL) particles and the accumulation of cholesteryl ester (CE) in high density lipoprotein (HDL...

journal_title：European journal of clinical investigation

authors： Sakai N,Yamashita S,Hirano K,Ishigami M,Arai T,Kobayashi K,Funahashi T,Matsuzawa Y

更新日期：1995-05-01 00:00:00

abstract：BACKGROUND:Nowadays there is an increased interest in the role of aortic stiffness in the pathophysiology of heart failure (HF), as it is a major determinant of left ventricular (LV) performance. We aimed at assessing the predictive value of the aortic stiffness parameters, measured by echocardiography, in patients aff...

journal_title：European journal of clinical investigation

authors： Sciatti E,Vizzardi E,Bonadei I,Fabbricatore D,Prati F,Pagnoni M,Metra M

更新日期：2018-07-01 00:00:00

abstract：BACKGROUND:Adiponectin is an insulin-sensitizing, antiatherogenic and anti-inflammatory adipocytokine that circulates in three isoforms: a trimer [low-molecular weight (LMW)], a hexamer (trimer-dimer) of medium molecular weight (MMW) and a multimeric high molecular weight (HMW) isoform. Evidence is accumulating that HM...

journal_title：European journal of clinical investigation

authors： Kaser S,Tatarczyk T,Stadlmayr A,Ciardi C,Ress C,Tschoner A,Sandhofer A,Paulweber B,Ebenbichler CF,Patsch JR

更新日期：2008-11-01 00:00:00

abstract：INTRODUCTION:Smoking is associated with dyslipidaemia, particularly raised plasma triglycerides and reduced high-density lipoprotein (HDL)-cholesterol and a delayed clearance of triglyceride in fat tolerance tests. The aim of this study was to investigate whether these phenomena could be explained by a reduced lipoprot...

journal_title：European journal of clinical investigation

authors： Freeman DJ,Caslake MJ,Griffin BA,Hinnie J,Tan CE,Watson TD,Packard CJ,Shepherd J

更新日期：1998-07-01 00:00:00

abstract：BACKGROUND:Observational studies have shown that high levels of serum uric acid (UA) were associated with atrial fibrillation (AF). However, the causal effect of urate on the risk of AF is still unknown. To clarify the potential causal association between UA and AF, we performed a Mendelian randomization (MR) analysis ...

journal_title：European journal of clinical investigation

authors： Hong M,Park JW,Yang PS,Hwang I,Kim TH,Yu HT,Uhm JS,Joung B,Lee MH,Jee SH,Pak HN

更新日期：2020-10-01 00:00:00

abstract：:Taurodeoxycholic acid increases the incidence of aspirin induced gastric bleeding in rats and in vitro is well bound by Aludrox (aluminium hydroxide) and poorly bound by Maalox (aluminium hydroxide and magnesium hydroxide). We studied the relevance of this binding, as demonstrated in vitro, by observing the effect of ...

journal_title：European journal of clinical investigation

authors： Morgan RJ,Nelson LM,Russell RI,Plevin T

更新日期：1980-12-01 00:00:00

abstract：:To diagnose hypolactasia, determination of lactase enzyme activity in small intestinal biopsy material is considered to be the golden standard. Because of its strongly invasive character and the sampling problems, alternative methods have been looked for. We analysed the 13C-glucose response in serum after consumption...

journal_title：European journal of clinical investigation

authors： Vonk RJ,Stellaard F,Priebe MG,Koetse HA,Hagedoorn RE,De Bruijn S,Elzinga H,Lenoir-Wijnkoop I,Antoine JM

更新日期：2001-03-01 00:00:00