Lipid parameters in patients with acute coronary syndromes versus stable coronary artery disease.

abstract：:Combined 47Calcium kinetic and calcium balance studies with correction for dermal calcium loss were performed in thirteen patients with primary hyperparathyroidism (PHP), in whom serum bone-Gla-protein (S-BGP) was measured, and in ten matched controls. Dietary calcium was normal in PHP but both net (7.9 +/- 1.4 mmol C...

journal_title：European journal of clinical investigation

authors： Charles P,Mosekilde L,Jensen FT

更新日期：1986-08-01 00:00:00

abstract：AIMS:This study estimated the resource implications and budget impact of managing adults with Fabry disease in Italy, from the perspective of the Servizio Sanitario Nazionale (SSN). METHODS:A decision model was constructed using published clinical outcomes and clinician-derived resource utilisation estimates depicting...

journal_title：European journal of clinical investigation

authors： Guest JF,Concolino D,Di Vito R,Feliciani C,Parini R,Zampetti A

更新日期：2011-07-01 00:00:00

abstract：BACKGROUND:Over the past decades, the prevalence of obesity has markedly increased worldwide. Stress is recognized as a substantial contributor to increased body weight; therefore, stress management interventions, especially cognitive behavioural, are becoming increasingly popular. The impact of stress management on st...

journal_title：European journal of clinical investigation

authors： Simos DS,Kokkinos A,Tentolouris N,Dimosthenopoulos C,Mantzou E,Artemiadis A,Bacopoulou F,Nicolaides NC,Kosta O,Chrousos GP,Darviri C

更新日期：2019-10-01 00:00:00

abstract：BACKGROUND/AIMS:Nitric oxide synthase (NOS) 3-deficient (NOS-3 KO) mice have an increased systemic arterial pressure but develop portal hypertension to the same extent as wildtype (WT) mice. We hypothesized that other vasodilators in the portal circulation compensate for the lack in NOS-3 activity. We used quantitative...

journal_title：European journal of clinical investigation

authors： Biecker E,Sägesser H,Reichen J

更新日期：2004-04-01 00:00:00

abstract：BACKGROUND:Glucocorticosteroids are effective in the treatment of allergic rhinitis, a disease characterized by a variety of symptoms, e.g. rhinorrhea and itching. The time course of symptomatic relief for allergic rhinitis by steroids has not been examined in detail to date, although the onset of steroid action is one...

journal_title：European journal of clinical investigation

authors： Tillmann HC,Stuck BA,Feuring M,Rossol-Haseroth K,Tran BM,Lösel R,Schmidt BM,Hörmann K,Wehling M,Schultz A

更新日期：2004-01-01 00:00:00

abstract：BACKGROUND:Acute ischaemic stroke (AIS) triggers both systemic and neurovascular inflammation, influencing poststroke recovery. In smokers with AIS, inflammation might be further upregulated, increasing ischaemia/reperfusion injury. Here, the predictive value of leucocyte and adhesion molecules levels on poststroke out...

journal_title：European journal of clinical investigation

authors： Liberale L,Montecucco F,Bonaventura A,Casetta I,Seraceni S,Trentini A,Padroni M,Dallegri F,Fainardi E,Carbone F

更新日期：2017-10-01 00:00:00

abstract：:In nine patients with non-malignant diseases undergoing major upper abdominal surgery, the mechanism of the postoperative fibrinolytic shut-down was investigated because of its potential significance for postoperative deep vein thrombosis by employing new and specific methods for assessing and stimulating the fibrinol...

journal_title：European journal of clinical investigation

authors： D'Angelo A,Kluft C,Verheijen JH,Rijken DC,Mozzi E,Mannucci PM

更新日期：1985-12-01 00:00:00

abstract：:Bradykinin infusion has been shown to improve glucose metabolism in non-insulin-dependent diabetic subjects (NIDD). Therefore, we tested the following hypothesis: inhibition of Kininase II, the bradykinin (BK) degrading enzyme, by captopril may also improve glucose metabolism in NIDD. Immediate effects of captopril on...

journal_title：European journal of clinical investigation

authors： Jauch KW,Hartl W,Guenther B,Wicklmayr M,Rett K,Dietze G

更新日期：1987-10-01 00:00:00

abstract：BACKGROUND:Cold ischaemic (CI) injury is associated with reduced renal graft function and survival. However, there is little evidence on the benefits of reducing CI injury within a 24 h period in donation after cardiac death (DCD) kidney transplantation. METHODS:Porcine kidneys subjected to 10-min warm ischaemia were ...

journal_title：European journal of clinical investigation

authors： Hosgood SA,Bagul A,Nicholson ML

更新日期：2011-03-01 00:00:00

abstract：:Deficient leucocyte sphingomyelinase activity has been demonstrated in a patient with the sea-blue histiocyte syndrome. Family studies revealed that two other cases previously diagnosed on clinical and histochemical criteria also had a pronounced diminution of sphingomyelinase activity. Both parents of the affected in...

journal_title：European journal of clinical investigation

authors： Fried K,Beer S,Krespin HI,Leiba H,Djaldetti M,Zitman D,Klibansky C

更新日期：1978-08-01 00:00:00

abstract：BACKGROUND:Preliminary data suggest that serum uric acid (SUA) could be involved in the prognosis of chronic heart failure (HF). The aim of our study was to test the relationship between SUA and left ventricular ejection fraction (EF%) in a cohort of elderly hypertensive outpatients with chronic HF. DESIGN:We consecut...

journal_title：European journal of clinical investigation

authors： Borghi C,Cosentino ER,Rinaldi ER,Cicero AF

更新日期：2014-06-01 00:00:00

abstract：:Quinidine is known to reduce the renal clearance of digoxin, but this effect does not completely explain the influence of quinidine on the total clearance of digoxin. We therefore studied the effect of quinidine administration on biliary clearance of digoxin in five patients with atrial fibrillation. Biliary clearance...

journal_title：European journal of clinical investigation

authors： Angelin B,Arvidsson A,Dahlqvist R,Hedman A,Schenck-Gustafsson K

更新日期：1987-06-01 00:00:00

abstract：:Deoxyribonucleic acid synthesis requires adequate cellular concentrations of the four deoxyribonucleoside triphosphates. Using a sensitive enzymic assay, we have measured the concentrations (pools) of these compounds in human bone marrow cells and in lymphocytes. The mean concentrations (pmol/10(6) cells) in normal hu...

journal_title：European journal of clinical investigation

authors： Tattersall MH,Lavoie A,Ganeshaguru K,Tripp E,Hoffbrand AV

更新日期：1975-04-01 00:00:00

abstract：:We measured the renal haemodynamic and proteinuric response to a meat meal (MM) in ten persistently proteinuric insulin-dependent diabetic patients in a randomized cross-over study of 3 weeks on low protein diet (LPD) or normal protein intake (NPD). On LPD, protein intake (0.64 +/- 0.05 vs 1.15 +/- 0.09 g kg-1 body we...

journal_title：European journal of clinical investigation

authors： Pinto JR,Bending JJ,Dodds RA,Viberti GC

更新日期：1991-04-01 00:00:00

abstract：:The pathogenesis of alcoholic fatty liver is unknown, but several causes have been proposed based on biochemical findings. These include the metabolism of alcohol leading to a shift in the cytosolic [NAD+]/ [NADH] ratio to reduction, which in turn causes a direct inhibition of beta-oxidation and enhanced triacylglycer...

journal_title：European journal of clinical investigation

authors： Eaton S,Record CO,Bartlett K

更新日期：1997-09-01 00:00:00

abstract：BACKGROUND:Antihyperglycemic drugs have been linked to new-onset atrial fibrillation (NAF). However, the effect of the different classes of antihyperglycemic drugs on the development of NAF in elderly patients has not been well studied. In this study, we investigated the association between different classes of antihyp...

journal_title：European journal of clinical investigation

authors： Chen HY,Yang FY,Jong GP,Liou YS

更新日期：2017-05-01 00:00:00

abstract：:The classical view of aldosterone actions via the mineralocorticoid receptor (MR) limited to control of fluid balance and blood pressure homoeostasis has been progressively overcome by clinical and experimental evidence emphasizing the pleiotropic role of MR activation in the pathogenesis of cardiovascular disease. Cl...

journal_title：European journal of clinical investigation

authors： Galuppo P,Bauersachs J

更新日期：2012-10-01 00:00:00

abstract：BACKGROUND:Age is one the factors associated with poor prognosis in acute coronary syndromes (ACS) and elderly patients are a high-risk collective with few parameters for mid-term cardiovascular stratification. We aimed to assess the predictive value of ankle-brachial index (ABI) in patients (> 75 years) for 1-year mor...

journal_title：European journal of clinical investigation

authors： Cordero A,Morillas P,Bertomeu-González V,Quiles J,Soria F,Guindo J,Mazón P,Anguita M,Rodríguez-Padial L,González-Juanatey JR,Bertomeu-Martínez V,en nombre de los investigadores del estudio PAMISCA.

更新日期：2011-12-01 00:00:00

abstract：BACKGROUND:It has been speculated that oral hypoglycaemic agents that block K-ATP channels could potentially increase blood pressure by blocking such channels in vascular myocytes. No information about this issue exists regarding nateglinide. DESIGN:A multicentre, double-blind, placebo-controlled, randomized trial was...

journal_title：European journal of clinical investigation

authors： González-Clemente JM,Spanish Nateglinide Study Group.

更新日期：2008-03-01 00:00:00

abstract：:Type III hyperlipoproteinaemia (HLP) is usually associated with homozygosity for apolipoprotein (apo) E2 (arg-158-->Cys). We identified a 46-year-old white female with severe hyperlipidaemia and the heterozygous apo E3/2* phenotype. Typical clinical characteristics of type III HLP, i.e. palmar xanthomas (orange-yellow...

journal_title：European journal of clinical investigation

authors： Feussner G,Albanese M,Mann WA,Valencia A,Schuster H

更新日期：1996-01-01 00:00:00

abstract：BACKGROUND:Many chronic diseases are adversely affected by elevated iron levels. It has been speculated that this relationship is mediated by increased oxidative stress, due to the ability of iron to generate reactive oxygen species. The aim of this study was to assess the relationship between elevated iron levels and ...

journal_title：European journal of clinical investigation

authors： Aranda N,Fernandez-Cao JC,Tous M,Arija V

更新日期：2016-06-01 00:00:00

abstract：BACKGROUND:In mutations of the low-density lipoprotein (LDL) receptor gene, the defect of internalization is caused by a mutation in the cytoplasmic domain of the receptor linked with exons 17 and 18, and the O-linked sugar domain linked with exon 15 has been speculated not to affect the function of the receptor. Here,...

journal_title：European journal of clinical investigation

authors： Tashiro J,Endo M,Bujo H,Shinomiya M,Morisaki N,Saito Y

更新日期：1998-09-01 00:00:00

abstract：:The venous system plays a pivotal role in volume and blood pressure homeostasis. We tested the hypothesis that the visco-elastic properties of the peripheral venous system are reduced in patients with (incipient) diabetic nephropathy. Twenty-two normotensive patients with long-term insulin-dependent diabetes mellitus ...

journal_title：European journal of clinical investigation

authors： Schaper NC,Houben AJ,Schoon Y,Kooman JP,Huvers FC,Nieuwenhuijzen Kruseman AC

更新日期：1994-06-01 00:00:00

abstract：BACKGROUND:Several studies have reported a significant gender difference in low-density lipoprotein (LDL) size, with men being characterized by smaller, denser LDL particles than women, and it has been suggested that the contribution of the greater accumulation of visceral adipose tissue in men compared with women may ...

journal_title：European journal of clinical investigation

authors： Lemieux I,Pascot A,Lamarche B,Prud'homme D,Nadeau A,Bergeron J,Després JP

更新日期：2002-12-01 00:00:00

abstract：:A kindred in which several members have otherwise typical acute intermittent porphyria but normal erythrocyte uroporphyrinogen-I-synthase activity has been described from Finland. We studied two porphyric members of this kindred, two patients with typical acute intermittent porphyria, and two healthy controls using th...

journal_title：European journal of clinical investigation

authors： Mustajoki P,Tenhunen R

更新日期：1985-10-01 00:00:00

abstract：:Increased plasma levels of soluble adhesion molecules are associated with an increased risk of atherothrombosis. The pathophysiological mechanisms responsible for these associations are not known. The aim of the present study was to investigate the association of soluble intercellular adhesion molecule-1 (sICAM-1) con...

journal_title：European journal of clinical investigation

authors： Becker A,van Hinsbergh VW,Jager A,Kostense PJ,Dekker JM,Nijpels G,Heine RJ,Bouter LM,Stehouwer CD

更新日期：2002-01-01 00:00:00

abstract：:To determine if the sex differences in clearance of long chain fatty acids by the liver observed in the rat are relevant to humans, the authors isolated hepatocytes from human adult males and females (five per group) and measured the initial (unidirectional) clearance of [3H]-palmitate from buffer containing albumin. ...

journal_title：European journal of clinical investigation

authors： Pond SM,Gordon RA,Bass L

更新日期：1996-01-01 00:00:00

abstract：BACKGROUND:Based on a report of a marked increase in the erythropoietin concentration ([EPO]) a few hours after the cessation of a single 2-h session of O(2) breathing, short periods of O(2) administration have been advocated as a therapy for anaemia. Accordingly, the purpose of the present study was to evaluate this t...

journal_title：European journal of clinical investigation

authors： Keramidas ME,Norman B,Gustafsson T,Eiken O,Mekjavic IB

更新日期：2012-03-01 00:00:00

abstract：BACKGROUND:To compare the administration of furosemide with placebo on the subjective perception of dyspnoea in patients with acute pulmonary oedema because of hypertensive crisis. Design  Randomized, controlled and double-blinded clinical trial. SETTING:Municipal emergency medical service system and university-based ...

journal_title：European journal of clinical investigation

authors： Holzer-Richling N,Holzer M,Herkner H,Riedmüller E,Havel C,Kaff A,Malzer R,Schreiber W

更新日期：2011-06-01 00:00:00

abstract：:Bile acid kinetics and biliary lipid composition were determined in ten hypothyroid patients before and after treatment with L-thyroxine. Hypothyroid patients had normal synthesis rates of cholic acid and chenodeoxycholic acid. Hormone treatment, which lowered plasma cholesterol by about 35%, stimulated the formation ...

journal_title：European journal of clinical investigation

authors： Angelin B,Einarsson K,Leijd B

更新日期：1983-02-01 00:00:00