当前位置： SCI文献检索 > EUROPEAN JOURNAL OF CLINICAL INVESTIGATION期刊下所有文献 > Effect of low protein diet on the renal response to meat ingestion in diabetic nephropathy.

Effect of low protein diet on the renal response to meat ingestion in diabetic nephropathy.

Abstract：

:We measured the renal haemodynamic and proteinuric response to a meat meal (MM) in ten persistently proteinuric insulin-dependent diabetic patients in a randomized cross-over study of 3 weeks on low protein diet (LPD) or normal protein intake (NPD). On LPD, protein intake (0.64 +/- 0.05 vs 1.15 +/- 0.09 g kg-1 body weight (BW) per day, P less than 0.001), plasma urea (6.6 +/- 1.3 vs 11.0 +/- 2.0 mmol l-1, P less than 0.01) and urea appearance (0.06 +/- 0.01 vs 0.16 +/- 0.03 gN kg-1 body weight per day, P less than 0.001) were lower. Baseline glomerular filtration rate (GFR), renal plasma flow (RPF) and renal vascular resistance (RVR) were similar on the two diets and there were no significant average changes in these variables after the meat meal on either diet (NPD, before vs after MM: GFR: 67 +/- 11 vs 71 +/- 13 ml min-1 1.73 m-2; RPF: 479 +/- 70 vs 512 +/- 81 ml min-1 1.73 m-2; RVR: 181 +/- 45 vs 179 +/- 52 mmHg min-1 l-1); (LPD, before vs after MM: GFR: 64 +/- 10 vs 67 +/- 11 ml min-1 1.73 m-2; RPF: 506 +/- 60 vs 533 + 52 ml min-1 1.73 m-2; RVR: 151 +/- 28 vs 146 +/- 32 mmHg min-1 l-1). However, all patients with baseline GFR above 60 ml min-1 1.73 m-2 showed a GFR rise in response to the meat meal on both diets, while patients with lower baseline values tended to reduce their GRF.(ABSTRACT TRUNCATED AT 250 WORDS)

journal_name

Eur J Clin Invest

journal_title

European journal of clinical investigation

authors

Pinto JR,Bending JJ,Dodds RA,Viberti GC

doi

10.1111/j.1365-2362.1991.tb01807.x

subject

Has Abstract

pub_date

1991-04-01 00:00:00

pages

175-83

issue

2

eissn

0014-2972

issn

1365-2362

journal_volume

21

pub_type

临床试验,杂志文章,随机对照试验

相关文献

EUROPEAN JOURNAL OF CLINICAL INVESTIGATION文献大全
  • Circulating anti-(xanthine oxidoreductase) antibodies in healthy human adults.

    abstract：:Levels of free anti-(xanthine oxidoreductase) (XOR) antibodies in the serum of normal healthy human subjects were determined, using both human and bovine enzyme as antigen, in an enzyme-linked immunosorbent assay (ELISA). Levels of IgM class anti-(human XOR) antibodies were found to be particularly high (mean values r...

    journal_title：European journal of clinical investigation

    pub_type： 杂志文章

    doi：10.1046/j.1365-2362.1997.1550704.x

    authors： Benboubetra M,Gleeson A,Harris CP,Khan J,Arrar L,Brennand D,Reid J,Reckless JD,Harrison R

    更新日期：1997-07-01 00:00:00

  • Aquaporin-1 and 8 expression in the gallbladder mucosa might not be associated with the development of gallbladder stones in humans.

    abstract：BACKGROUND:Cholecystolithiasis is a highly prevalent condition in the Western world. Gallbladder stone-related conditions represent the second most common gastrointestinal pathology. Cholesterol stones represent over 80% of gallstones. Cholesterol stones develop secondary to crystallization of bile cholesterol. Water r...

    journal_title：European journal of clinical investigation

    pub_type： 杂志文章

    doi：10.1111/eci.12586

    authors： Ambe PC,Gödde D,Zirngibl H,Störkel S

    更新日期：2016-03-01 00:00:00

  • Role of various tissues in apo(a) fragmentation and excretion of fragments by the kidney.

    abstract：BACKGROUND:Lipoprotein(a) [Lp(a)] is an atherothrombotic plasma lipoprotein with unknown function. Little is known about the catabolism of this lipoprotein, in particular the steps related to apolipoprotein(a) [apo(a)] fragmentation and excretion by the kidney. MATERIAL AND METHODS:High plasma levels (up to 9 mg dL(-1...

    journal_title：European journal of clinical investigation

    pub_type： 杂志文章

    doi：10.1046/j.1365-2362.2001.00811.x

    authors： Frank S,Hrzenjak A,Blaschitz A,Dohr G,Kostner GM

    更新日期：2001-06-01 00:00:00

  • Platelet noradrenaline release in patients with familial hypercholesterolaemia.

    abstract：:We have examined resting and thrombin (0.3 units ml-1) induced release of noradrenaline by washed platelets from 15 normal subjects and eight patients with heterozygous familial hypercholesterolaemia. Platelets from both normal and hypercholesterolaemic subjects showed irreversible aggregation with 0.3 units ml-1 thro...

    journal_title：European journal of clinical investigation

    pub_type： 杂志文章

    doi：10.1111/j.1365-2362.1989.tb00225.x

    authors： Smith CC,Wilson AP,Prichard BN,Betteridge DJ

    更新日期：1989-06-01 00:00:00

  • Lipoprotein modifications during dietary treatment in patients with primary type V hyperlipoproteinaemia.

    abstract：:Type V hyperlipoproteinaemia is a disorder of lipid transport characterized by the accumulation in serum of chylomicrons and very low density lipoproteins. The purpose of the study was the analysis of serum lipids and lipoproteins by ultracentrifugation in nine patients with primary type V hyperlipoproteinaemia before...

    journal_title：European journal of clinical investigation

    pub_type： 杂志文章

    doi：10.1111/j.1365-2362.1986.tb01322.x

    authors： Manzato E,Marin R,Gasparotto A,Baggio G,Martini S,Gabelli C,Crepaldi G

    更新日期：1986-04-01 00:00:00

  • Comprehensive geriatric assessment in older adults with cancer: Recommendations by the Italian Society of Geriatrics and Gerontology (SIGG).

    abstract：INTRODUCTION:Optimizing the approach to older adults with cancer is now a priority given the increasing frequency of new cancer diagnoses that are made in the older population. The comprehensive geriatric assessment (CGA) represents the gold-standard for (1) defining prognosis and ability to withstand cancer treatments...

    journal_title：European journal of clinical investigation

    pub_type： 杂志文章

    doi：10.1111/eci.13347

    authors： Fusco D,Ferrini A,Pasqualetti G,Giannotti C,Cesari M,Laudisio A,Ballestrero A,Scabini S,Odetti PR,Colloca GF,Monzani F,Nencioni A,Antonelli Incalzi R,Monacelli F,Oncogeriatrics Group of the Italian Society of Gerontology, Ger

    更新日期：2021-01-01 00:00:00

  • Effect of passive smoking on blood lymphocyte apoptosis in children.

    abstract：BACKGROUND:Passive smoking is a well-known risk factor for both recurrent respiratory infections and disturbed lipid profile. Whether passive smoking problems are related to altered lymphocyte survival and its relation to altered lipid profile are the points of concern in this work. MATERIALS AND METHODS:Urinary cotin...

    journal_title：European journal of clinical investigation

    pub_type： 杂志文章

    doi：10.1111/j.1365-2362.2010.02420.x

    authors： El-Hodhod MA,Hamdy AM,Ahmed MB,Youssef SR,Aly SM

    更新日期：2011-04-01 00:00:00

  • DALI-the first human whole-blood low-density lipoprotein and lipoprotein (a) apheresis system in clinical use: procedure and clinical results.

    abstract：BACKGROUND:The DALI low-density lipoprotein (LDL) apheresis system is the first whole-blood apheresis system in regular clinical use. DALI stands for direct adsorption of lipoproteins, which describes the basic principle of operation of this newly developed LDL apheresis procedure. METHODS:The selective removal of LDL...

    journal_title：European journal of clinical investigation

    pub_type： 临床试验,杂志文章,多中心研究

    doi：10.1046/j.1365-2362.1998.00395.x

    authors： Dräger LJ,Julius U,Kraenzle K,Schaper J,Toepfer M,Zygan K,Otto V,Steinhagen-Thiessen E

    更新日期：1998-12-01 00:00:00

  • Lymphocyte responses following open and minimally invasive thoracic surgery.

    abstract：BACKGROUND:Immunosuppression associated with surgery may predispose to increased tumour growth or recurrence. Lymphocytes are central components of the immune network, signalling specific and non-specific responses in tumour immunosurveillance. This study was therefore designed to compare the effects of minimally invas...

    journal_title：European journal of clinical investigation

    pub_type： 临床试验,杂志文章,随机对照试验

    doi：10.1046/j.1365-2362.2000.00622.x

    authors： Leaver HA,Craig SR,Yap PL,Walker WS

    更新日期：2000-03-01 00:00:00

  • Basal cyclic AMP levels in human blood mononuclear cells.

    abstract：:Basal cyclic AMP levels in blood mononuclear cells from healthy human donors has been studied. A great variation in cyclic AMP content ranging from below 2 to 20 pmol 10(-6) cells was seen. Incubation of the cells at 37 degrees C mostly showed a time-dependent decrease in basal cyclic AMP, levelling off after 16 h. Wh...

    journal_title：European journal of clinical investigation

    pub_type： 杂志文章

    doi：10.1111/j.1365-2362.1984.tb01179.x

    authors： Svenson M,Permin H,Wiik A

    更新日期：1984-08-01 00:00:00

  • Acute and chronic exposure of rat intestinal mucosa to dextran promotes SGLTI-mediated glucose transport.

    abstract：BACKGROUND:The intestinal handling of dextran, an alpha-1,6-linked glucose polymer, is poor compared with starch, and some ingested dextran might therefore reach the lower small intestine. As luminal sugar up-regulates SGLT1 (sodium-dependent glucose transporter) locally, we report the effects of a dextran-enriched die...

    journal_title：European journal of clinical investigation

    pub_type： 杂志文章

    doi：10.1046/j.1365-2362.1998.00352.x

    authors： Debnam ES,Denholm EE,Grimble GK

    更新日期：1998-08-01 00:00:00

  • Fibronectin in synovial fluid and tissue in rheumatoid arthritis.

    abstract：:Fibronectin is a glycoprotein found in body fluids, loose connective tissue matrix and in basement membranes. Fibronectin in rheumatoid arthritis synovial fluid was immunologically indistinguishable from the plasma form, as shown by double-diffusion analysis. Fibronectin isolated from rheumatoid synovial fluid by affi...

    journal_title：European journal of clinical investigation

    pub_type： 杂志文章

    doi：10.1111/j.1365-2362.1981.tb01842.x

    authors： Vartio T,Vaheri A,Von Essen R,Isomäki H,Stenman S

    更新日期：1981-06-01 00:00:00

  • Somatostatin and the immune and haematopoetic system; a review.

    abstract：:SS-R and SS have been demonstrated in non-pathological and pathological lymphoid tissue and may play a regulatory, mostly inhibitory, role in the immune response. SS is produced by lymphocytes and monocytes which suggests an autocrine or paracrine regulatory role, but SS may be released as well by nerve endings. It ca...

    journal_title：European journal of clinical investigation

    pub_type： 杂志文章,评审

    doi：10.1111/j.1365-2362.1994.tb00972.x

    authors： van Hagen PM,Krenning EP,Kwekkeboom DJ,Reubi JC,Anker-Lugtenburg PJ,Löwenberg B,Lamberts SW

    更新日期：1994-02-01 00:00:00

  • Inflammatory imbalance between IL-10 and TNFalpha in unstable angina potential plaque stabilizing effects of IL-10.

    abstract：BACKGROUND:The pathogenesis of atherosclerosis and acute coronary syndromes involves inflammation and immunological mechanisms. We hypothesized that patients with unstable angina may have an imbalance between inflammatory and anti-inflammatory cytokines. DESIGN:Plasma levels of tumour necrosis factor (TNF)alpha and in...

    journal_title：European journal of clinical investigation

    pub_type： 杂志文章

    doi：10.1046/j.1365-2362.2002.01069.x

    authors： Waehre T,Halvorsen B,Damås JK,Yndestad A,Brosstad F,Gullestad L,Kjekshus J,Frøland SS,Aukrust P

    更新日期：2002-11-01 00:00:00

  • The type and time of menopause as decisive factors for bone mass changes.

    abstract：BACKGROUND:Early menopause, whether it be natural or surgical, is one of the established risk factors for osteoporosis. Surgical menopause, however, differs from natural menopause owing to the abrupt cessation of estrogen secretion. This study attempts to investigate the influence of menopause type on bone mineral dens...

    journal_title：European journal of clinical investigation

    pub_type： 杂志文章

    doi：10.1046/j.1365-2362.1999.00541.x

    authors： Hadjidakis D,Kokkinakis E,Sfakianakis M,Raptis SA

    更新日期：1999-10-01 00:00:00

  • Metastatic pheochromocytoma and paraganglioma.

    abstract：BACKGROUND:Metastatic pheochromocytomas (PCs) and paragangliomas (PGLs) are rare neuroendocrine tumours with a strong genetic background. DESIGN:We searched the PubMed database through February 2015 to identify studies characterizing metastatic PCs/PGLs as well as currently established and evolving therapies. RESULTS...

    journal_title：European journal of clinical investigation

    pub_type： 杂志文章,评审

    doi：10.1111/eci.12495

    authors： Angelousi A,Kassi E,Zografos G,Kaltsas G

    更新日期：2015-09-01 00:00:00

  • Topo IIα gene alterations correlated with survival in patients with diffuse large B-cell lymphoma.

    abstract：BACKGROUND:Topoisomerase IIα (topo IIα) protein expression has prognostic significance in many cancers. However, it is still unclear whether topo IIα protein expression and gene alterations play roles as prognostic factors in diffuse large B-cell lymphoma (DLBCL). MATERIALS AND METHODS:We selected 102 patients with DL...

    journal_title：European journal of clinical investigation

    pub_type： 杂志文章

    doi：10.1111/j.1365-2362.2011.02585.x

    authors： Chen Z,Wang J,Zhang H,Liu D,Li Y,Xu Y,Tan D,Chen D,Zhao X,Wang G

    更新日期：2012-03-01 00:00:00

  • Suppressive effect of COX2 inhibitor on the progression of adipose inflammation in high-fat-induced obese rats.

    abstract：BACKGROUND:The aim was to examine whether the inhibition of selective cyclooxygenase (COX) 2 activation could suppress the development of inflammatory reaction in visceral and subcutaneous abdominal fats of high-fat-induced obese rats. MATERIALS AND METHODS:The rats were fed separately regular diet (CONT), high-fat di...

    journal_title：European journal of clinical investigation

    pub_type： 杂志文章

    doi：10.1111/j.1365-2362.2009.02239.x

    authors： Hsieh PS,Lu KC,Chiang CF,Chen CH

    更新日期：2010-02-01 00:00:00

  • Short-term overt hypothyroidism induces discrete diastolic dysfunction in patients treated for differentiated thyroid carcinoma.

    abstract：BACKGROUND:Thyroid hormone has important effects on the cardiovascular system. The consequences of episodes of acute hypothyroidism on cardiac function have been investigated in only a few studies, and their results are inconclusive. Our objective was to investigate the effects of acute hypothyroidism on cardiac functi...

    journal_title：European journal of clinical investigation

    pub_type： 杂志文章

    doi：10.1111/j.1365-2362.2009.02088.x

    authors： Hoftijzer HC,Bax JJ,Heemstra KA,Bleeker GB,Delgado V,van der Klaauw AA,Romijn JA,Smit JW,Corssmit EP

    更新日期：2009-03-01 00:00:00

  • Symptom patterns can distinguish diverticular disease from irritable bowel syndrome.

    abstract：BACKGROUND:Diverticular disease (DD) and irritable bowel syndrome (IBS) share a similar symptom pattern. However, comparative studies are flawed by different age at onset of symptoms. We aimed to verify whether clinical features distinguish DD from IBS. MATERIALS AND METHODS:Patients with DD or IBS, matched for age an...

    journal_title：European journal of clinical investigation

    pub_type： 杂志文章,多中心研究

    doi：10.1111/eci.12152

    authors： Cuomo R,Barbara G,Andreozzi P,Bassotti G,Casetti T,Grassini M,Ierardi E,Maconi G,Marchi S,Sarnelli G,Savarino V,Usai P,Vozzella L,Annibale B

    更新日期：2013-11-01 00:00:00

  • Incomplete suppression of hepatic glucose production in non-insulin dependent diabetes mellitus measured with [6,6-2H2]glucose enriched glucose infusion during hyperinsulinaemic euglycaemic clamps.

    abstract：:We have minimized methodological errors in the isotope dilution technique by using stable isotope, [6,6-2H2]glucose, thus avoiding the problem of contamination of tritiated glucose tracers and, by maintaining a constant plasma tracer enrichment have reduced error due to mixing transients. Using these modifications we ...

    journal_title：European journal of clinical investigation

    pub_type： 杂志文章

    doi：10.1111/j.1365-2362.1992.tb01458.x

    authors： Powrie JK,Smith GD,Hennessy TR,Shojaee-Moradie F,Kelly JM,Sönksen PH,Jones RH

    更新日期：1992-04-01 00:00:00

  • Sex differences in initial clearance of palmitate by human hepatocytes.

    abstract：:To determine if the sex differences in clearance of long chain fatty acids by the liver observed in the rat are relevant to humans, the authors isolated hepatocytes from human adult males and females (five per group) and measured the initial (unidirectional) clearance of [3H]-palmitate from buffer containing albumin. ...

    journal_title：European journal of clinical investigation

    pub_type： 杂志文章

    doi：10.1046/j.1365-2362.1996.101246.x

    authors： Pond SM,Gordon RA,Bass L

    更新日期：1996-01-01 00:00:00

  • Effect of pronounced weight loss on visceral fat, liver steatosis and adiponectin isoforms.

    abstract：BACKGROUND:Weight loss induced by bariatric surgery is an effective method to reverse obesity and comorbidities. The aim of this prospective weight loss study was to investigate changes of body fat distribution in relation to adiponectin and its isoforms and further to investigate the influence of both body fat distrib...

    journal_title：European journal of clinical investigation

    pub_type： 杂志文章

    doi：10.1111/j.1365-2362.2008.01929.x

    authors： Engl J,Sturm W,Sandhofer A,Kaser S,Tschoner A,Tatarczyk T,Weiss H,Tilg H,Patsch JR,Ebenbichler CF

    更新日期：2008-04-01 00:00:00

  • The influence of sorafenib on hepatic encephalopathy and the mechanistic survey in cirrhotic rats.

    abstract：BACKGROUND:Sorafenib, a multikinase inhibitor that inhibits angiogenesis and carcinogenesis, has been used for patients with advanced hepatocellular carcinoma. However, sporadic cases have been reported with the development of hepatic encephalopathy (HE) after sorafenib treatment, mostly in those with cirrhosis. Liver ...

    journal_title：European journal of clinical investigation

    pub_type： 杂志文章

    doi：10.1111/eci.12006

    authors： Hsu SJ,Hsin IF,Lin YL,Chen YC,Huang HC,Lee FY,Lin HC,Chang CC,Lee SD

    更新日期：2012-12-01 00:00:00

  • Plasma angiopoietin-1, angiopoietin-2 and Tie-2 in breast and prostate cancer: a comparison with VEGF and Flt-1.

    abstract：BACKGROUND:Angiogenesis is essential for tumour growth and metastasis, and is coordinated by several classes of growth factors mediating their effect through receptors linked, in turn, to tyrosine kinase. These growth factors include angiopoietin-1 (Ang-1), angiopoietin-2 (Ang-2) and vascular endothelial growth factor ...

    journal_title：European journal of clinical investigation

    pub_type： 杂志文章

    doi：10.1046/j.1365-2362.2003.01243.x

    authors： Caine GJ,Blann AD,Stonelake PS,Ryan P,Lip GY

    更新日期：2003-10-01 00:00:00

  • Risk score to predict mortality in continuous ambulatory peritoneal dialysis patients.

    abstract：BACKGROUND:Patients with continuous ambulatory peritoneal dialysis (CAPD) have high all-cause mortality risk that varies extensively among different conditions. The objective of this study was to develop and validate risk models to predict the 2-year all-cause mortality risks of CAPD patients. MATERIAL AND METHODS:A t...

    journal_title：European journal of clinical investigation

    pub_type： 杂志文章

    doi：10.1111/eci.12344

    authors： Zhao C,Luo Q,Xia X,He F,Peng F,Yu X,Huang F

    更新日期：2014-11-01 00:00:00

  • Treatment with hormone replacement therapy lowers remnant lipoprotein particles in healthy postmenopausal women: results from a randomized trial.

    abstract：BACKGROUND:Recent evidence indicates that remnant lipoprotein particles (RLPs) may play a role in atherosclerosis. Remnant lipoprotein particles have been suggested to be the most atherogenic particles among the triglyceride-rich lipoproteins. In particular, these triglyceride-rich particles were identified as an indep...

    journal_title：European journal of clinical investigation

    pub_type： 临床试验,杂志文章,随机对照试验

    doi：10.1046/j.1365-2362.2003.01163.x

    authors： Ossewaarde ME,Dallinga-Thie GM,Bots ML,van der Schouw YT,Rabelink TJ,Grobbee DE,Westerveld HT

    更新日期：2003-05-01 00:00:00

  • Effect of vitamins C and E on insulin resistance in diabetes: a meta-analysis study.

    abstract：BACKGROUND:Data regarding the effect of vitamin C (VC) and vitamin E (VE) supplementation on insulin resistance in type 2 diabetes mellitus (T2DM) are controversial. We aimed to systematically review the current data on this topic. MATERIALS AND METHODS:All randomized controlled trials (RCTs) conducted to assess the e...

    journal_title：European journal of clinical investigation

    pub_type： 杂志文章,meta分析

    doi：10.1111/eci.12534

    authors： Khodaeian M,Tabatabaei-Malazy O,Qorbani M,Farzadfar F,Amini P,Larijani B

    更新日期：2015-11-01 00:00:00

  • Insulin and glucagon secretion by pancreatic islets from nondiabetic and diabetic sand rats (Psammomys obesus).

    abstract：:The secretion of insulin and glucagon was investigated in pancreatic islets from diabetic and nondiabetic sand rats of similar age and weight. The metabolic characterization was based on an intraperitoneal glucose tolerance test. Compared to nondiabetic animals diabetic sand rats had a diminished insulin content in th...

    journal_title：European journal of clinical investigation

    pub_type： 杂志文章

    doi：10.1111/j.1365-2362.1976.tb00497.x

    authors： Hahn HJ,Schäfer H,Gottschling HD,Fiedler H

    更新日期：1976-01-30 00:00:00

  • The cytoplasmic Ca2+ response to glucose as an indicator of impairment of the pancreatic beta-cell function.

    abstract：:The effects of glucose on the cytoplasmic Ca2+ concentration (Ca2+i) regulating insulin release were investigated using pancreatic beta-cells representative for the normal and diabetic situations. Increase of the glucose concentration resulted in a slight lowering of Ca2+i followed by a rise, often manifested as high ...

    journal_title：European journal of clinical investigation

    pub_type： 杂志文章

    doi：10.1111/j.1365-2362.1990.tb01771.x

    authors： Hellman B,Berne C,Grapengiesser E,Grill V,Gylfe E,Lund PE

    更新日期：1990-10-01 00:00:00