Mineralocorticoid receptor activation in myocardial infarction and failure: recent advances.

abstract：:Arterial lumen narrowing and vascular occlusion is the actual cause of morbidity and mortality in atherosclerotic disease. Collateral artery formation (arteriogenesis) refers to an active remodelling of non-functional vascular anastomoses to functional collateral arteries, capable to bypass the site of obstruction and...

journal_title：European journal of clinical investigation

authors： de Groot D,Pasterkamp G,Hoefer IE

更新日期：2009-12-01 00:00:00

abstract：BACKGROUND:Acute hyperglycaemia is known to inhibit jejunal interdigestive motility. This study was undertaken to establish the effects of hyperglycaemia on fed jejunal motility and small intestinal transit time, and to establish if the effects of hyperglycaemia are mediated in part by hyperinsulinaemia. METHODS:Nine ...

journal_title：European journal of clinical investigation

authors： Byrne MM,Pluntke K,Wank U,Schirra J,Arnold R,Göke B,Katschinski M

更新日期：1998-01-01 00:00:00

abstract：:beta-Adrenoceptor binding on peripheral blood mononuclear cells (PBMC) of healthy adult volunteers was investigated using the radioligand 125iodo-cyanopindolol (ICYP). Saturation binding studies were performed with nine different concentrations of ICYP. Receptor density and affinity were calculated by Scatchard plots....

journal_title：European journal of clinical investigation

authors： Griese M,Körholz U,Körholz D,Seeger K,Wahn V,Reinhardt D

更新日期：1988-04-01 00:00:00

abstract：BACKGROUND:It is well known that space travel cause post-flight orthostatic hypotension and it was assumed that autonomic cardiovascular control deteriorates in space. Lower body negative pressure (LBNP) was used to assess autonomic function of the cardiovascular system. METHODS:LBNP tests were performed on six crew-m...

journal_title：European journal of clinical investigation

authors： Baisch F,Beck L,Blomqvist G,Wolfram G,Drescher J,Rome JL,Drummer C

更新日期：2000-12-01 00:00:00

abstract：BACKGROUND:Acute ischaemic stroke (AIS) triggers both systemic and neurovascular inflammation, influencing poststroke recovery. In smokers with AIS, inflammation might be further upregulated, increasing ischaemia/reperfusion injury. Here, the predictive value of leucocyte and adhesion molecules levels on poststroke out...

journal_title：European journal of clinical investigation

authors： Liberale L,Montecucco F,Bonaventura A,Casetta I,Seraceni S,Trentini A,Padroni M,Dallegri F,Fainardi E,Carbone F

更新日期：2017-10-01 00:00:00

abstract：:To diagnose hypolactasia, determination of lactase enzyme activity in small intestinal biopsy material is considered to be the golden standard. Because of its strongly invasive character and the sampling problems, alternative methods have been looked for. We analysed the 13C-glucose response in serum after consumption...

journal_title：European journal of clinical investigation

authors： Vonk RJ,Stellaard F,Priebe MG,Koetse HA,Hagedoorn RE,De Bruijn S,Elzinga H,Lenoir-Wijnkoop I,Antoine JM

更新日期：2001-03-01 00:00:00

abstract：BACKGROUND:There is growing evidence that the predictive value of HDL cholesterol levels for cardiovascular risk stratification is limited in patients with coronary artery disease (CAD). HDL function seems to be a more sensitive surrogate of cardiovascular risk estimation than simple serum levels. Therefore, we aimed t...

journal_title：European journal of clinical investigation

authors： Distelmaier K,Wiesbauer F,Blessberger H,Oravec S,Schrutka L,Binder C,Dostal E,Schillinger M,Wojta J,Lang IM,Maurer G,Huber K,Goliasch G

更新日期：2015-07-01 00:00:00

abstract：BACKGROUND:To reveal detailed histopathological changes, virus distributions, immunologic properties and multi-omic features caused by SARS-CoV-2 in the explanted lungs from the world's first successful lung transplantation of a COVID-19 patient. MATERIALS AND METHODS:A total of 36 samples were collected from the lung...

journal_title：European journal of clinical investigation

authors： Chen XJ,Li K,Xu L,Yu YJ,Wu B,He YL,Zhao WE,Li D,Luan CX,Hu L,Wang J,Ding JJ,Yu YF,Li JX,Tan ZM,Liu XF,Wei D,Zhang ZH,Guo XJ,Su C,Hu ZB,Guo YS,Chen JY,Chen F

更新日期：2021-01-01 00:00:00

abstract：:We recently reported that chloride-depletion metabolic alkalosis (CDMA) results in renal losses of Na, K, and water. In these studies we investigated whether CDMA (induced using a new model that avoids external changes in Na and water balance) was also associated with internal Na and water shifts out of the ECF. CDMA ...

journal_title：European journal of clinical investigation

authors： Garella S,Cohen JJ,Northrup TE

更新日期：1991-06-01 00:00:00

abstract：BACKGROUND:Memory and cognitive functions are known to decline with advancing age. Studies have suggested that this may be due to a decrease in cholinergic function in the brains of elderly people. This review aims to assess studies documented in the literature dealing with the 'scopolamine model' of dementia. METHODS...

journal_title：European journal of clinical investigation

authors： Ebert U,Kirch W

更新日期：1998-11-01 00:00:00

abstract：BACKGROUND:Clinical practice guidelines recommend regular kidney function monitoring in atrial fibrillation patients on nonvitamin K oral anticoagulants (NOAC); however, information regarding compliance with these recommendations in daily life conditions is scarce. We sought to determine the compliance with kidney func...

journal_title：European journal of clinical investigation

authors： Andreu Cayuelas JM,Caro Martínez C,Flores Blanco PJ,Elvira Ruiz G,Albendin Iglesias H,Cerezo Manchado JJ,Bailen Lorenzo JL,Januzzi JL,García Alberola A,Manzano-Fernández S

更新日期：2018-06-01 00:00:00

abstract：BACKGROUND:Increased intestinal permeability in cirrhosis exerts a pivotal role in the pathogenesis of spontaneous bacterial peritonitis and other complications of cirrhosis through promotion of systemic endotoxemia. This study was designed to investigate whether the expression of tight junction (TJ) proteins, which re...

journal_title：European journal of clinical investigation

authors： Assimakopoulos SF,Tsamandas AC,Tsiaoussis GI,Karatza E,Triantos C,Vagianos CE,Spiliopoulou I,Kaltezioti V,Charonis A,Nikolopoulou VN,Scopa CD,Thomopoulos KC

更新日期：2012-04-01 00:00:00

abstract：BACKGROUND:Many studies have focused on the physiological parameters and genetic predisposition of subjects presenting both obesity and insulin resistance (IR) and it has been suggested that the peroxisome proliferator-activated receptor gamma 2 (PPARgamma2) Pro12Ala variant may contribute to the observed variability i...

journal_title：European journal of clinical investigation

authors： Macias-Gonzalez M,Moreno-Santos I,García-Almeida JM,Tinahones FJ,Garcia-Fuentes E

更新日期：2009-11-01 00:00:00

abstract：BACKGROUND:Predictors of gingival enlargement in patients treated with anti-epileptics have not been previously assessed. This study was conducted to determine, with the aid of two indices that score vertical and horizontal overgrowth, the prevalence and risk factors for gingival enlargement in patients treated with ph...

journal_title：European journal of clinical investigation

authors： Brunet L,Miranda J,Roset P,Berini L,Farré M,Mendieta C

更新日期：2001-09-01 00:00:00

abstract：:The serum concentrations of collagen type IV,7S, collagen type IV,nc1, and aminoterminal type III procollagen peptide immunoreactive components were measured by means of specific radioimmunoassays during development of granulation tissue in rats. The results were compared with tissue deposition of basement membranes a...

journal_title：European journal of clinical investigation

authors： Hørslev-Petersen K,Pedersen LR,Bentsen KD,Brocks D,Garbarsch C,Kim KY,Hahn EG,Schuppan D,Lorenzen I

更新日期：1988-08-01 00:00:00

abstract：:Bile acid kinetics and biliary lipid composition were determined in ten hypothyroid patients before and after treatment with L-thyroxine. Hypothyroid patients had normal synthesis rates of cholic acid and chenodeoxycholic acid. Hormone treatment, which lowered plasma cholesterol by about 35%, stimulated the formation ...

journal_title：European journal of clinical investigation

authors： Angelin B,Einarsson K,Leijd B

更新日期：1983-02-01 00:00:00

abstract：BACKGROUND:Glomerulonephritis clusters in families. However, infections are common inducers of glomerulonephritis and may also cluster in families. Studies of adoptees and their biological and adoptive parents may disentangle genetic from environmental causes of familial clustering. This is the first adoption study aim...

journal_title：European journal of clinical investigation

authors： Akrawi DS,Zöller B,Fjellstedt E,Sundquist J,Sundquist K,PirouziFard M

更新日期：2019-08-01 00:00:00

abstract：:Diabetes Mellitus in its early stages, is associated with kidney enlargement and increased glomerular filtration rate in humans and in rats. The present study was designed to clarify the direct effect of diabetes on serum and tissue angiotensin converting enzyme (ACE) activity in streptozotocin-induced diabetic rats. ...

journal_title：European journal of clinical investigation

authors： Erman A,van Dyk DJ,Chen-Gal B,Giler ID,Rosenfeld JB,Boner G

更新日期：1993-10-01 00:00:00

abstract：BACKGROUND:Acute hyperglycaemia is known to increase gastrointestinal (GI) sensitivity in healthy subjects and may contribute to the increased prevalence of GI symptoms in diabetes patients. The aim of this study was to evaluate the effect of acute hyperglycaemia on perception and brain responses to painful visceral an...

journal_title：European journal of clinical investigation

authors： Frøkjaer JB,Søfteland E,Graversen C,Dimcevski G,Drewes AM

更新日期：2010-10-01 00:00:00

abstract：BACKGROUND:Bone marrow (BM) histology/immunohistochemistry, KIT D816V mutation analysis and serum tryptase measurements are mandatory tools for diagnosis of systemic mastocytosis (SM). MATERIALS AND METHODS:Within the 'German Registry of Disorders on Eosinophils and Mast Cells', we identified 65 patients with SM who h...

journal_title：European journal of clinical investigation

authors： Jawhar M,Schwaab J,Horny HP,Sotlar K,Naumann N,Fabarius A,Valent P,Cross NC,Hofmann WK,Metzgeroth G,Reiter A

更新日期：2016-05-01 00:00:00

abstract：:A haemolytically inactive alpha-mobile complement C8 component was identified by crossed immunoelectrophoresis in a 27-year-old male with recurrent meningococcal infections and absence of complement mediated serum haemolytic activity. The patient's serum/plasma contained no demonstrable normal C8. C8 inhibitor activit...

journal_title：European journal of clinical investigation

authors： Brandslund I,Teisner B,Strate M,Grunnet N,Svehag SE,Isager H,Wang P

更新日期：1983-04-01 00:00:00

abstract：:Alpha-naphthyl-isothiocyanate (ANIT)-induced intrahepatic cholangitis was associated with significant polyuria in rats. The urine output in the experimental rats was about two and a half to four fold higher than that in the controls. The polyuria was accompanied by polydypsia and disappeared when water intake was limi...

journal_title：European journal of clinical investigation

authors： Tur-Kaspa R,Adler R,Popovtzer MM,Eliakim M

更新日期：1983-02-01 00:00:00

abstract：:We have examined resting and thrombin (0.3 units ml-1) induced release of noradrenaline by washed platelets from 15 normal subjects and eight patients with heterozygous familial hypercholesterolaemia. Platelets from both normal and hypercholesterolaemic subjects showed irreversible aggregation with 0.3 units ml-1 thro...

journal_title：European journal of clinical investigation

authors： Smith CC,Wilson AP,Prichard BN,Betteridge DJ

更新日期：1989-06-01 00:00:00

abstract：:In this study the muscarinic receptor antagonist atropine and the cholecystokinin (CCK)-A receptor antagonist loxiglumide were used to investigate the relative importance of cholinergic and CCK-mediated regulation of intestinal phase antro-pyloro-duodenal motility. Plasma levels of gastrointestinal hormones [pancreati...

journal_title：European journal of clinical investigation

authors： Katschinski M,Schirra J,Begliner C,Langbein S,Wank U,D'Amato M,Arnold R

更新日期：1996-07-01 00:00:00

abstract：:To assess the degree of immune system activation associated with addiction or hepatotropic viruses infection, we examined 60 HIV-negative heroin addicts for the presence of hepatitis B virus (HBV) infection markers, hepatitis C virus antibodies (anti-HCV), various auto-antibodies, and serum levels of soluble interleuk...

journal_title：European journal of clinical investigation

authors： Dalekos GN,Manoussakis MN,Zervou E,Tsianos EV,Moutsopoulos HM

更新日期：1993-04-01 00:00:00

abstract：:Hyperthyroidism is associated with an increase in both osteoblast and osteoclast activity. We have previously shown that, in vitro, osteoclasts do not respond directly to tri-iodothyronine to increase bone resorption but that the effect is mediated by another bone cell, probably the osteoblast. To investigate this iss...

journal_title：European journal of clinical investigation

authors： Allain TJ,Yen PM,Flanagan AM,McGregor AM

更新日期：1996-05-01 00:00:00

abstract：BACKGROUND:In atherosclerosis, both reductions and elevations in plasma levels of antioxidants have been reported. This study investigated total antioxidant capacity of plasma from subjects with atherosclerotic disease. MATERIALS AND METHODS:The study population consisted of 48 men with or without carotid atherosclero...

journal_title：European journal of clinical investigation

authors： Reinisch N,Kiechl S,Mayr C,Schratzberger P,Dunzendorfer S,Kähler CM,Buratti T,Willeit J,Wiedermann CJ

更新日期：1998-10-01 00:00:00

abstract：:The impact of running and menstrual disturbances on regional and total body fat distribution and serum lipids was investigated in 205 women. Body composition was measured by dual-energy X-ray absorptiometry. The total fat mass in the elite runners was approximately half of the normally active's (7.3 [0.48] kg vs. 14.3...

journal_title：European journal of clinical investigation

authors： Hetland ML,Haarbo J,Christiansen C

更新日期：1995-08-01 00:00:00

abstract：BACKGROUND:Cholecystolithiasis is a highly prevalent condition in the Western world. Gallbladder stone-related conditions represent the second most common gastrointestinal pathology. Cholesterol stones represent over 80% of gallstones. Cholesterol stones develop secondary to crystallization of bile cholesterol. Water r...

journal_title：European journal of clinical investigation

authors： Ambe PC,Gödde D,Zirngibl H,Störkel S

更新日期：2016-03-01 00:00:00

abstract：BACKGROUND:Plasmacytoid dendritic cells (pDCs) are multifunctional bone-marrow-derived immune cells that are key players in bridging the innate and adaptive immune systems. Activation of pDCs through toll-like receptor agonists has proven to be an effective treatment for some neoplastic disorders. MATERIALS AND METHOD...

journal_title：European journal of clinical investigation

authors： Lombardi VC,Khaiboullina SF,Rizvanov AA

更新日期：2015-01-01 00:00:00