Strength and endurance training lead to different post exercise glucose profiles in diabetic participants using a continuous subcutaneous glucose monitoring system.


BACKGROUND:Although both strength training (ST) and endurance training (ET) seem to be beneficial in type 2 diabetes mellitus (T2D), little is known about post-exercise glucose profiles. The objective of the study was to report changes in blood glucose (BG) values after a 4-month ET and ST programme now that a device for continuous glucose monitoring has become available. MATERIALS AND METHODS:Fifteen participants, comprising four men age 56.5 +/- 0.9 years and 11 women age 57.4 +/- 0.9 years with T2D, were monitored with the MiniMed (Northridge, CA, USA) continuous glucose monitoring system (CGMS) for 48 h before and after 4 months of ET or ST. The ST consisted of three sets at the beginning, increasing to six sets per week at the end of the training period, including all major muscle groups and ET performed with an intensity of maximal oxygen uptake of 60% and a volume beginning at 15 min and advancing to a maximum of 30 min three times a week. RESULTS:A total of 17,549 single BG measurements pretraining (619.7 +/- 39.8) and post-training (550.3 +/- 30.1) were recorded, correlating to an average of 585 +/- 25.3 potential measurements per participant at the beginning and at the end of the study. The change in BG-value between the beginning (132 mg dL(-1)) and the end (118 mg dL(-1)) for all participants was significant (P = 0.028). The improvement in BG-value for the ST programme was significant (P = 0.02) but for the ET no significant change was measured (P = 0.48). Glycaemic control improved in the ST group and the mean BG was reduced by 15.6% (Cl 3-25%). CONCLUSION:In conclusion, the CGMS may be a useful tool in monitoring improvements in glycaemic control after different exercise programmes. Additionally, the CGMS may help to identify asymptomatic hypoglycaemia or hyperglycaemia after training programmes.


Eur J Clin Invest


Cauza E,Hanusch-Enserer U,Strasser B,Kostner K,Dunky A,Haber P





Has Abstract


2005-12-01 00:00:00














  • Secondary prophylaxis of variceal bleeding for cirrhotic patients: a multiple-treatments meta-analysis.

    abstract:OBJECTIVE:To evaluate comprehensively the effects of 12 prophylaxis interventions for secondary prophylaxis of variceal bleeding using multiple-treatments meta-analysis. METHODS:PubMed, EMBASE and the Cochrane Library were searched prior to November 2011. Randomized controlled trials (RCTs) comparing the interventions...

    journal_title:European journal of clinical investigation

    pub_type: 杂志文章,meta分析,评审


    authors: Shi KQ,Liu WY,Pan ZZ,Ling XF,Chen SL,Chen YP,Fan YC,Zheng MH

    更新日期:2013-08-01 00:00:00

  • Predominant role of obesity/insulin resistance in oxidative stress development.

    abstract:BACKGROUND:  Hyperlipidaemia, hyperglycaemia and hyperinsulinaemia, hallmarks of the postprandial state, have been also associated with increased oxidative stress and lipoprotein oxidation contributing to vascular injury and atherosclerosis. However, the specific links among metabolic disorders, postprandial state, ins...

    journal_title:European journal of clinical investigation

    pub_type: 杂志文章


    authors: D'Archivio M,Annuzzi G,Varì R,Filesi C,Giacco R,Scazzocchio B,Santangelo C,Giovannini C,Rivellese AA,Masella R

    更新日期:2012-01-01 00:00:00

  • The relationship between renal volume and histology in obese and nonobese kidney donors.

    abstract:BACKGROUND:Obesity and related kidney diseases have become a global epidemic problem. However, the underlying pathogenesis of obesity-related renal diseases has not been clearly understood. In this study, we explored the link between renal volume (RV) determined by computed tomography (CT) and renal histology together ...

    journal_title:European journal of clinical investigation

    pub_type: 杂志文章


    authors: Tatar E,Sen S,Harman M,Kircelli F,Gungor O,Sarsik B,Asci G,Hoscoskun C,Basci A,Toz H

    更新日期:2015-06-01 00:00:00

  • Multiple abnormalities in the transfer of phospholipids from VLDL and LDL to HDL in non-insulin-dependent diabetes.

    abstract::Transfers or exchanges of cholesterol esters and triglycerides between lipoproteins are mediated by a specialized protein referred to as cholesteryl ester transfer protein (CETP), whereas those of phospholipids (PLs) are facilitated by both CETP and a specific phospholipid transfer protein (PLTP). In the present study...

    journal_title:European journal of clinical investigation

    pub_type: 杂志文章


    authors: Elchebly M,Pulcini T,Porokhov B,Berthezene F,Ponsin G

    更新日期:1996-03-01 00:00:00

  • Cardiac biomarkers and survival in haemodialysis patients.

    abstract:BACKGROUND:In dialysis patients, cardiac troponin T (cTNT) is often elevated despite the absence of acute myocardial ischaemia, and amino-terminal pro-B-natriuretic peptide (NT-proBNP) is markedly higher compared to non-haemodialysis patients. In a longitudinal observation, we evaluated the association of cTNT and NT-p...

    journal_title:European journal of clinical investigation

    pub_type: 杂志文章


    authors: Sommerer C,Beimler J,Schwenger V,Heckele N,Katus HA,Giannitsis E,Zeier M

    更新日期:2007-05-01 00:00:00

  • Markers of platelet activation in coronary heart disease patients.

    abstract::We have applied flow cytometry to the detection of activated platelets in patients with coronary heart disease. Paraformaldehyde-fixed platelets were incubated with one of the following monoclonal antibodies (MAbs): Bx-1 (anti-GP Ib), AP-2 (anti-GP IIb-IIIa complex), VH10 (anti-GMP-140, a glycoprotein of the alpha-gra...

    journal_title:European journal of clinical investigation

    pub_type: 杂志文章


    authors: Nurden AT,Macchi L,Bihour C,Durrieu C,Besse P,Nurden P

    更新日期:1994-02-01 00:00:00

  • Procalcitonin measurement to screen medullary thyroid carcinoma: A prospective evaluation in a series of 2705 patients with thyroid nodules.

    abstract:BACKGROUND:To prospectively evaluate the role of procalcitonin (PCT) in screening of patients with thyroid nodules for medullary thyroid carcinoma (MTC). MATERIALS AND METHODS:We measured PCT in 2705 patients with thyroid nodules referred to our centre between January 2011 and December 2017. Those with a positive PCT ...

    journal_title:European journal of clinical investigation

    pub_type: 杂志文章


    authors: Giovanella L,Imperiali M,Piccardo A,Taborelli M,Verburg FA,Daurizio F,Trimboli P

    更新日期:2018-06-01 00:00:00

  • Effect of oral prostaglandin E2 on DNA turnover in gastric and intestinal epithelia of the rat.

    abstract::The mucosal incorporation and clearance of a DNA precursor was examined in the rat stomach and intestine following oral treatment with natural prostaglandin E2 (PGE2) or 15(R) 15 methyl prostaglandin E2 (Me PGE2). Control groups received vehicle or pentagastrin. After five days of treatment animals were labelled with ...

    journal_title:European journal of clinical investigation

    pub_type: 杂志文章


    authors: Johansson C,Uribe A,Rubio C,Isenberg JI

    更新日期:1986-12-01 00:00:00

  • High-density lipoprotein from end-stage renal disease patients exhibits superior cardioprotection and increase in sphingosine-1-phosphate.

    abstract:BACKGROUND:Chronic kidney disease (CKD) exacerbates the risk of death due to cardiovascular disease (CVD). Modifications to blood lipid metabolism which manifest as increases in circulating triglycerides and reductions in high-density lipoprotein (HDL) cholesterol are thought to contribute to increased risk. In CKD pat...

    journal_title:European journal of clinical investigation

    pub_type: 杂志文章


    authors: Brinck JW,Thomas A,Brulhart-Meynet MC,Lauer E,Frej C,Dahlbäck B,Stenvinkel P,James RW,Frias MA

    更新日期:2018-02-01 00:00:00

  • Pulse pressure and prognosis in patients with heart failure with reduced ejection fraction.

    abstract:BACKGROUND:A high pulse pressure (PP) is associated with adverse cardiovascular (CV) outcomes; however, this relationship may be reversed in patients with heart failure with reduced ejection fraction (HFREF). METHODS:Patients from the WARCEF trial with left ventricular ejection fraction ≤35% were included. PP was divi...

    journal_title:European journal of clinical investigation

    pub_type: 杂志文章


    authors: Shah N,Qian M,Di Tullio MR,Graham S,Mann DL,Sacco RL,Lip GYH,Labovitz AJ,Ponikowski P,Lok DJ,Anker SD,Teerlink JR,Thompson JLP,Homma S,Freudenberger RS,WARCEF Investigators.

    更新日期:2019-02-23 00:00:00

  • Regenerative pulmonary medicine: potential and promise, pitfalls and challenges.

    abstract:BACKGROUND:Chronic lung diseases contribute significantly to the morbidity and mortality of the population. There are few effective treatments for many chronic lung diseases, and even fewer therapies that can arrest or reverse the progress of the disease. DESIGN:In this review, we present the current state of regenera...

    journal_title:European journal of clinical investigation

    pub_type: 杂志文章,评审


    authors: Anversa P,Perrella MA,Kourembanas S,Choi AM,Loscalzo J

    更新日期:2012-08-01 00:00:00

  • The association between CYBA gene C242T variant and risk of metabolic syndrome.

    abstract:BACKGROUND:Both inflammation and oxidative stress may contribute to pathogenesis of metabolic syndrome (MetS). The C242T polymorphism (rs4673) in the CYBA gene, as the main components of NAD (P) H oxidase, causes inter-individual variability in the enzyme activity. We aimed to investigate the association between this p...

    journal_title:European journal of clinical investigation

    pub_type: 杂志文章


    authors: Pourgholi L,Pourgholi F,Ziaee S,Goodarzynejad H,Hosseindokht M,Boroumand M,Mandegary A

    更新日期:2020-09-01 00:00:00

  • Bile acid metabolism in hypothyroid subjects: response to substitution therapy.

    abstract::Bile acid kinetics and biliary lipid composition were determined in ten hypothyroid patients before and after treatment with L-thyroxine. Hypothyroid patients had normal synthesis rates of cholic acid and chenodeoxycholic acid. Hormone treatment, which lowered plasma cholesterol by about 35%, stimulated the formation ...

    journal_title:European journal of clinical investigation

    pub_type: 杂志文章


    authors: Angelin B,Einarsson K,Leijd B

    更新日期:1983-02-01 00:00:00

  • Visceral Fibromuscular Dysplasia: From asymptomatic disorder to emergency.

    abstract::Fibromuscular dysplasia (FMD) is an idiopathic, segmental, non-atherosclerotic and non-inflammatory disease of the musculature of arterial walls, leading to stenosis of small and medium-sized arteries, mostly involving renal and cervical arteries. As a result of better and more systematic screening, it appears that in...

    journal_title:European journal of clinical investigation

    pub_type: 杂志文章,评审


    authors: Van der Niepen P,van Tussenbroek F,Devos H,Debing E,Di Monaco S,Goffette P,Astarci P,Persu A

    更新日期:2018-11-01 00:00:00

  • Evidence for a Na-K-ATPase-inhibitor in erythrocytes of patients with essential hypertension.

    abstract::ATPase activities were determined in haemolysed and dialysed erythrocytes and in haemoglobin-free membranes of twenty patients with essential hypertension and twenty normotensive controls. Ouabain-sensitive ATPase (Na-K-ATPase) activity of haemolysate but not that of membranes was decreased in hypertensives whereas ou...

    journal_title:European journal of clinical investigation

    pub_type: 杂志文章


    authors: Walter U,Müller S

    更新日期:1985-08-01 00:00:00

  • Platelet glycoprotein IIb-IIIa and size are increased in acute myocardial infarction.

    abstract::Platelet aggregation, which plays an important role in acute myocardial infarction (AMI), is mediated by fibrinogen binding to the platelet membrane glycoprotein (GP)IIb-IIIa (CD41). This study measured the relative number of GPIIb-IIIa complexes on platelets from patients immediately following AMI (n = 14) compared w...

    journal_title:European journal of clinical investigation

    pub_type: 杂志文章


    authors: Giles H,Smith RE,Martin JF

    更新日期:1994-01-01 00:00:00

  • Increased rate of lumbar spondylolisthesis in rheumatoid arthritis: A case-control study.

    abstract:OBJECTIVE:The aim of this study was to compare the prevalence of lumbar spondylolisthesis (SPL) in patients suffering from low back pain (LBP) with or without rheumatoid arthritis (RA) and to identify potential factors associated with SPL in patients with RA. METHODS:We performed a case-control study. Cases and contro...

    journal_title:European journal of clinical investigation

    pub_type: 杂志文章


    authors: Hagege B,Tubach F,Alfaiate T,Forien M,Dieudé P,Ottaviani S

    更新日期:2018-09-01 00:00:00

  • Calcium affects biomarkers of colon carcinogenesis after right hemicolectomy.

    abstract:BACKGROUND:In Western societies colonic cancer most frequently develops in the distal colon, largely as a result of the composition of the diet. Modulation of dietary factors is therefore an attractive modality to reduce colorectal cancer risk. This study aims to evaluate the potentially protective effects of calcium i...

    journal_title:European journal of clinical investigation

    pub_type: 临床试验,杂志文章,随机对照试验


    authors: van Gorkom BA,van der Meer R,Karrenbeld A,van der Sluis T,Zwart N,Termont DS,Boersma-van Ek W,de Vries EG,Kleibeuker JH

    更新日期:2002-09-01 00:00:00

  • Multiple biochemical effects in the pathogenesis of alcoholic fatty liver.

    abstract::The pathogenesis of alcoholic fatty liver is unknown, but several causes have been proposed based on biochemical findings. These include the metabolism of alcohol leading to a shift in the cytosolic [NAD+]/ [NADH] ratio to reduction, which in turn causes a direct inhibition of beta-oxidation and enhanced triacylglycer...

    journal_title:European journal of clinical investigation

    pub_type: 杂志文章,评审


    authors: Eaton S,Record CO,Bartlett K

    更新日期:1997-09-01 00:00:00

  • Increased number of ouabain binding sites in lymphocytes from borderline hypertensives.

    abstract::Lymphocytes were used as a cellular model for the in vitro measurements of maximal ouabain binding sites in order to assess any changes in young men at increased risk of developing essential hypertension, and to analyse whether any such changes were associated to borderline hypertension and/or heredity. Four groups we...

    journal_title:European journal of clinical investigation

    pub_type: 杂志文章


    authors: Nielsen JR,Pedersen KE,Klitgaard NA,Johansen T

    更新日期:1989-02-01 00:00:00

  • Relation between insulin kinetics and insulin sensitivity in pregnancy.

    abstract:BACKGROUND:Different time-concentration profiles of plasma insulin following insulin modification of a frequently sampled intravenous glucose-tolerance-test (FSIVGTT) were observed in a study investigating maternal metabolism and fetal macrosomia. We aimed to investigate whether these differences were related to the vo...

    journal_title:European journal of clinical investigation

    pub_type: 杂志文章


    authors: Jolly MC,Hovorka R,Godsland I,Amin R,Lawrence N,Anyaoku V,Johnston D,Robinson S

    更新日期:2003-08-01 00:00:00

  • Thymosin β4 protects C57BL/6 mice from bleomycin-induced damage in the lung.

    abstract:BACKGROUND:Thymosin β4 (Tβ4) was recently found at high concentration in the bronchoalveolar lavage fluid (BALF) of scleroderma patients with lung involvement. It has been hypothesized that Tβ4 may exert a cyto-protective effect during lung injury because lower Tβ4 levels were associated with interstitial lung disease ...

    journal_title:European journal of clinical investigation

    pub_type: 杂志文章


    authors: Conte E,Genovese T,Gili E,Esposito E,Iemmolo M,Fruciano M,Fagone E,Pistorio MP,Crimi N,Cuzzocrea S,Vancheri C

    更新日期:2013-03-01 00:00:00

  • Prevalence of coronary atherosclerosis and reclassification of cardiovascular risk in Spanish population by coronary computed tomography angiography: EVA study.

    abstract:BACKGROUND:A more complete assessment of coronary artery disease (CAD) can be performed by coronary computed tomography angiography (CCTA). The aim was to assess the prevalence, distribution and characteristics of coronary artery disease (CAD) and the reclassification of cardiovascular risk by CCTA in an asymptomatic S...

    journal_title:European journal of clinical investigation

    pub_type: 杂志文章


    authors: García-Ortiz L,Barreiro-Perez M,Merchan-Gómez S,Ignacio Recio-Rodriguez J,Sánchez-Aguadero N,Alonso-Dominguez R,Lugones-Sanchez C,Rodríguez-Sanchez E,Sanchez PL,Gómez-Marcos MA,on behalf EVA investigators.

    更新日期:2020-09-01 00:00:00

  • Platelet turnover in advanced diabetes.

    abstract::There is considerable information to indicate that when there is vessel injury, platelets can play a major role in the development of atherosclerosis and its thromboembolic complications in the non-diabetic population. Diabetes is a disease associated with an increased risk of vascular complications, but the nature of...

    journal_title:European journal of clinical investigation

    pub_type: 杂志文章,评审


    authors: Winocour PD

    更新日期:1994-02-01 00:00:00

  • The effects of fish oil on gene expression in patients with polycystic ovary syndrome.

    abstract:BACKGROUND:This study was conducted to determine the effects of fish oil administration on gene expression related to insulin, lipid and inflammation in women with polycystic ovary syndrome (PCOS). MATERIALS AND METHODS:This randomized, double-blind, placebo-controlled trial was conducted among 40 subjects with PCOS, ...

    journal_title:European journal of clinical investigation

    pub_type: 杂志文章,随机对照试验


    authors: Rahmani E,Jamilian M,Dadpour B,Nezami Z,Vahedpoor Z,Mahmoodi S,Aghadavod E,Taghizadeh M,Beiki Hassan A,Asemi Z

    更新日期:2018-03-01 00:00:00

  • Assessment of interferon cardiotoxicity with quantitative radionuclide angiocardiography.

    abstract::Three different types of cardiovascular sequelae attributed to interferon therapy have been reported: arrhythmia, ischaemic heart disease and cardiomyopathy. We evaluated the left ventricular ejection fraction (LVEF) during alpha interferon therapy (3 MU administered subcutaneously three times a week for 6 months) in ...

    journal_title:European journal of clinical investigation

    pub_type: 杂志文章


    authors: Sartori M,Andorno S,La Terra G,Pozzoli G,Rudoni M,Sacchetti GM,Inglese E,Aglietta M

    更新日期:1995-01-01 00:00:00

  • Thiopurine metabolism monitoring: implications in inflammatory bowel diseases.

    abstract:BACKGROUND:Thiopurines (TP) are widely used in the management of inflammatory bowel diseases. Side effects and inefficacy are a major concern as they lead to withdrawal of the drug. MATERIALS AND METHODS:Tools investigating TP metabolism are useful to avoid inadequate cessation of TP therapy. RESULTS:TP metabolism is...

    journal_title:European journal of clinical investigation

    pub_type: 杂志文章,评审


    authors: Dewit O,Starkel P,Roblin X

    更新日期:2010-11-01 00:00:00

  • Decrease in circulating plasmacytoid dendritic cells during short-term systemic normobaric hypoxia.

    abstract:BACKGROUND:During exposure to high altitude, the immune system is altered. During hypoxia, an increase in interleukin (IL)-6 and high sensitivity C-reactive protein (hs-CRP), and an increase in natural killer cells and decrease in T cells in blood was shown. However, the impact of hypoxia on dendritic cells has not bee...

    journal_title:European journal of clinical investigation

    pub_type: 杂志文章


    authors: Yilmaz A,Ratka J,Rohm I,Pistulli R,Goebel B,Asadi Y,Petri A,Kiehntopf M,Figulla HR,Jung C

    更新日期:2016-02-01 00:00:00

  • Patterns of co-occurrence of three single nucleotide polymorphisms of the 5,10-methylenetetrahydrofolate reductase gene in kidney transplant recipients.

    abstract:BACKGROUND:Recently, a new mutation of the 5,10-methylenetetrahydrofolate reductase (MTHFR) encoding gene was first described (1793G > A). Only few reports have studied the prevalence of this polymorphism, especially in combination with other MTHFR mutations (677C > T, 1298A > C). METHODS:We cross-sectionally identifi...

    journal_title:European journal of clinical investigation

    pub_type: 杂志文章


    authors: Winkelmayer WC,Sunder-Plassmann G,Huber A,Födinger M

    更新日期:2004-09-01 00:00:00

  • Is the renal kallikrein system relevant to sodium sensitivity in patients with essential hypertension.

    abstract::In twenty-five outpatients with essential hypertension, the relevance of renal kallikrein excretion for inter-individual differences in the blood pressure response to changes in dietary sodium intake was investigated. The patients were studied during 2 weeks of high (300 mmol) and 2 weeks of low (50-100 mmol) sodium i...

    journal_title:European journal of clinical investigation

    pub_type: 临床试验,杂志文章,随机对照试验


    authors: Koolen MI,Daha MR,van Brummelen P

    更新日期:1985-06-01 00:00:00