Endothelin-1 and vein graft occlusion in patients undergoing bypass surgery.

abstract：:Inheritance is a major determinant of increased sodium-lithium countertransport (SLC) activity in hypertension. However, hyperlipidaemia can also cause increased SLC activity in some individuals and it is difficult to distinguish this effect from the effect of hypertension. Erythrocyte SLC activity and its kinetic det...

journal_title：European journal of clinical investigation

authors： Rutherford PA,Thomas TH,Laker MF,Wilkinson R

更新日期：1992-11-01 00:00:00

abstract：:beta-Adrenoceptor binding on peripheral blood mononuclear cells (PBMC) of healthy adult volunteers was investigated using the radioligand 125iodo-cyanopindolol (ICYP). Saturation binding studies were performed with nine different concentrations of ICYP. Receptor density and affinity were calculated by Scatchard plots....

journal_title：European journal of clinical investigation

authors： Griese M,Körholz U,Körholz D,Seeger K,Wahn V,Reinhardt D

更新日期：1988-04-01 00:00:00

abstract：:Propranolol is used clinically as a prophylactic drug to prevent oesophageal variceal bleeding in cirrhotic patients with portal hypertension. Vascular hyporesponsiveness is a common characteristic of the portal hypertensive state. The present study aimed to investigate whether chronic administration of propranolol co...

journal_title：European journal of clinical investigation

authors： Huang YT,Lin HC,Tsai JF,Hou MC,Hong CY

更新日期：1997-07-01 00:00:00

abstract：BACKGROUND:Parental history of type 2 diabetes (T2D) is associated with cardiometabolic risk. We aimed to investigate the associations of parental history of T2D with cardiometabolic biomarkers and to subsequently investigate to what extent these putative associations were explained by modifiable factors. MATERIALS AN...

journal_title：European journal of clinical investigation

authors： Abbasi A,Corpeleijn E,van der Schouw YT,Stolk RP,Spijkerman A,van der A DL,Navis G,Bakker SJ,Beulens JW

更新日期：2012-09-01 00:00:00

abstract：:The urinary excretion of free light immunoglobulin chains IgG, IgA, and Fcγ fragment material has been estimated in 12 healthy individuals and 7 subjects with tubular or glomerular proteinuria. Measurements were carried out by immunochemical methods after separation of concentrated urinary immunoglobulin components by...

journal_title：European journal of clinical investigation

authors： Peterson PA,Berggård I

更新日期：1971-08-01 00:00:00

abstract：BACKGROUND:Soluble TWEAK (sTWEAK) and asymmetric dimethyl arginine (ADMA) concentrations have been associated with endothelial function in patients with chronic kidney disease (CKD). We tested the hypothesis that the improvement in endothelial function observed after renal transplantation is directly linked to the norm...

journal_title：European journal of clinical investigation

authors： Yilmaz MI,Sonmez A,Saglam M,Yaman H,Unal HU,Gok M,Cetinkaya H,Eyileten T,Oguz Y,Sari S,Yildirim AO,Vural A,Carrero JJ,Blanco-Colio LM

更新日期：2013-12-01 00:00:00

abstract：BACKGROUND:Experimental and clinical studies have suggested that inhibitors of the renin angiotensin system (RAS) might be useful to slow the progression of valvular calcification in patients with aortic stenosis (AS). OBJECTIVES:The aim of this study was to evaluate the relationships between the weight and tissue rem...

journal_title：European journal of clinical investigation

authors： Côté N,Couture C,Pibarot P,Després JP,Mathieu P

更新日期：2011-11-01 00:00:00

abstract：:We investigated the influence of sodium fluoride on polymorphonuclear leukocyte (PMN) adhesiveness in a healthy subject with low serum levels of fluoride. The PMN were separated from venous blood, and the percentages of adhered and unadhered cells were determined in vitro in plastic culture plates. The cells were cult...

journal_title：European journal of clinical investigation

authors： Gómez-Ubric JL,Liébana J,Gutiérrez J,Castillo A

更新日期：1992-10-01 00:00:00

abstract：BACKGROUND:There is ongoing controversy whether angiotensin-converting enzyme inhibitors (ACE-I) contribute to anaemia by causing hyporesponsiveness to erythropoiesis-stimulating agents (ESA). However, it is unknown whether or not plasma levels or area under the curve (AUC) of ACE-I are associated with responsiveness t...

journal_title：European journal of clinical investigation

authors： Winnicki W,Prehslauer A,Kletzmayr J,Herkner H,Sunder-Plassmann G,Brunner M,Hörl WH,Sengoelge G

更新日期：2012-10-01 00:00:00

abstract：BACKGROUND:Smoking remains the most important avoidable cause of global mortality. Even though the number of cigarette smokers declines in first world countries, the uses of alternative nicotine delivery products increase and may even surpass the sells of cigarettes. In this light, the explicit role of nicotine in the ...

journal_title：European journal of clinical investigation

authors： Babic M,Schuchardt M,Tölle M,van der Giet M

更新日期：2019-04-01 00:00:00

abstract：:To study the effect of glucagon immunoneutralization on postoperative changes of urea synthesis, hysterectomized rats were given one injection of a specific high titre antibody against pancreatic glucagon 24 h before operation raising the plasma glucagon binding capacity to values 10-20 times higher than the plasma gl...

journal_title：European journal of clinical investigation

authors： Heindorff H,Holst JJ,Almdal T,Vilstrup H

更新日期：1993-03-01 00:00:00

abstract：:Based on pathophysiological findings Lp(a) is considered to be a cardiovascular risk factor. The Göttingen Risk Incidence and Prevalence Study (GRIPS) provides the possibility to evaluate this impact of Lp(a) on the basis of a large prospective cohort study. GRIPS included 6002 men, aged 40-59.9 years at baseline. Dat...

journal_title：European journal of clinical investigation

authors： Cremer P,Nagel D,Labrot B,Mann H,Muche R,Elster H,Seidel D

更新日期：1994-07-01 00:00:00

abstract：:The collagenolytic activities were assayed in fibroblast cultures established from ten keratoconus and six control corneal explants. The assays included those for both type I and type IV collagenase. The amount of free, directly assayable type I collagenase was highly increased in the media of keratoconus primary cell...

journal_title：European journal of clinical investigation

authors： Ihalainen A,Salo T,Forsius H,Peltonen L

更新日期：1986-02-01 00:00:00

abstract：:The capillary permeability in human skeletal muscle, expressed as capillary diffusion capacity (CDC) for 51Cr-EDTA, was determined during exercise with a local clearance method in two groups of healthy male subjects: a younger group with a mean age of 30 years and an older one with a mean age of 58 years. The main fin...

journal_title：European journal of clinical investigation

authors： Berglund B,Efendić S,Strandell T,Luft R

更新日期：1979-10-01 00:00:00

abstract：:Platelet aggregation induced by collagen, ADP and epinephrine, was monitored in 150 type-II patients (115 type IIA and 35 type IIB) and compared with a reference group of normolipidaemic controls; in addition, malondialydehyde formation and thromboxane B2 were examined in a subsample of the type-IIA patients. Threshol...

journal_title：European journal of clinical investigation

authors： Tremoli E,Maderna P,Colli S,Morazzoni G,Sirtori M,Sirtori CR

更新日期：1984-10-01 00:00:00

abstract：:ATPase activities were determined in haemolysed and dialysed erythrocytes and in haemoglobin-free membranes of twenty patients with essential hypertension and twenty normotensive controls. Ouabain-sensitive ATPase (Na-K-ATPase) activity of haemolysate but not that of membranes was decreased in hypertensives whereas ou...

journal_title：European journal of clinical investigation

authors： Walter U,Müller S

更新日期：1985-08-01 00:00:00

abstract：OBJECTIVE:obesity-related microvascular dysfunction, including alterations in rhythmic changes in vascular diameter, so-called 'vasomotion', may be important in the clustering of obesity with other cardiovascular risk factors. Adipokines have been suggested to play a role in obesity-related vascular dysfunction. Altera...

journal_title：European journal of clinical investigation

authors： de Boer MP,Wijnstok NJ,Serné EH,Eringa EC,Stehouwer CD,Flyvbjerg A,Hoekstra T,Heymans MW,Meijer RI,Twisk JW,Smulders YM

更新日期：2014-07-01 00:00:00

abstract：BACKGROUND:Neutrophil-mediated inflammation was recently identified as an active contributor to athero-progression. Therapeutic strategies inhibiting neutrophil degranulation or recruitment were hypothesized to positively impact on plaque vulnerability. In this study, we investigated whether treatment with the recently...

journal_title：European journal of clinical investigation

authors： Da Silva AR,Lenglet S,Carbone F,Burger F,Roth A,Liberale L,Bonaventura A,Dallegri F,Stergiopulos N,Santos RA,Mach F,Fraga-Silva RA,Montecucco F

更新日期：2017-02-01 00:00:00

abstract：:Many diseases with a major public health impact are the result of complex interactions between environmental factors and multiple genes. In the past decade, methods for genome analysis, in particular quantitative trait locus (QTL) analysis in animal models, were developed to identify and localize the genes responsible...

journal_title：European journal of clinical investigation

authors： Hillebrandt S,Matern S,Lammert F

更新日期：2003-02-01 00:00:00

abstract：BACKGROUND:In dialysis patients, cardiac troponin T (cTNT) is often elevated despite the absence of acute myocardial ischaemia, and amino-terminal pro-B-natriuretic peptide (NT-proBNP) is markedly higher compared to non-haemodialysis patients. In a longitudinal observation, we evaluated the association of cTNT and NT-p...

journal_title：European journal of clinical investigation

authors： Sommerer C,Beimler J,Schwenger V,Heckele N,Katus HA,Giannitsis E,Zeier M

更新日期：2007-05-01 00:00:00

abstract：BACKGROUND:This study was conducted to determine the effects of fish oil administration on gene expression related to insulin, lipid and inflammation in women with polycystic ovary syndrome (PCOS). MATERIALS AND METHODS:This randomized, double-blind, placebo-controlled trial was conducted among 40 subjects with PCOS, ...

journal_title：European journal of clinical investigation

authors： Rahmani E,Jamilian M,Dadpour B,Nezami Z,Vahedpoor Z,Mahmoodi S,Aghadavod E,Taghizadeh M,Beiki Hassan A,Asemi Z

更新日期：2018-03-01 00:00:00

abstract：BACKGROUND:To determine the influence of chorioamnionitis and neonatal sepsis on procalcitonin (PCT) levels in very-low-birth-weight (VLBW) infants within the first week of life. DESIGN:PCT serum levels were measured in cord blood 1 h after delivery and on day 3 and day 7 of life. Chorioamnionitis and neonatal sepsis ...

journal_title：European journal of clinical investigation

authors： Janota J,Stranák Z,Bĕlohlávková S,Mudra K,Simák J

更新日期：2001-11-01 00:00:00

abstract：BACKGROUND:Changes in plasma leptin concentration and food intake occur during the menstrual cycle; because leptin regulates food intake, one could hypothesize that changes in plasma leptin concentration and in food intake are associated throughout the menstrual cycle. However, no data have ever been provided to suppor...

journal_title：European journal of clinical investigation

authors： Paolisso G,Rizzo MR,Mazziotti G,Rotondi M,Tagliamonte MR,Varricchio G,Carella C,Varricchio M

更新日期：1999-06-01 00:00:00

abstract：BACKGROUND:Plasma brain natriuretic peptide (BNP) is elevated in asymptomatic patients with various cardiac abnormalities. We tested the hypothesis that measuring BNP is useful for detecting asymptomatic patients with cardiac abnormalities who are not identified by conventional health check-up programmes. MATERIALS AN...

journal_title：European journal of clinical investigation

authors： Takase H,Toriyama T,Sugiura T,Takahashi A,Sugiyama M,Ohashi M,Ueda R,Dohi Y

更新日期：2007-04-01 00:00:00

abstract：:Currently available information on adipose tissue metabolism in man is mainly based on studies in vitro. In the present work adipose tissue lipid uptake was studied in vivo in man. 100 g glucose and 120 g milk fat with 10 microCi U-14C oleic acid were given in the overnight fasting state to eight women and 2 h after a...

journal_title：European journal of clinical investigation

authors： Mårin P,Rebuffé-Scrive M,Björntorp P

更新日期：1990-04-01 00:00:00

abstract：BACKGROUND:Carotid intima-media thickness and carotid plaque are well-established imaging markers used to capture different stages of the atherosclerotic disease process. We aimed to quantify to which extent carotid intima-media thickness predicts incidence of first-ever carotid plaque. MATERIALS AND METHODS:Two indep...

journal_title：European journal of clinical investigation

authors： Tschiderer L,Klingenschmid G,Seekircher L,Willeit P

更新日期：2020-04-01 00:00:00

abstract：BACKGROUND:Studies evaluating the relationship between soluble transferrin receptor (sTfR), a biomarker inversely related to body iron stores, and risk of type 2 diabetes mellitus (T2DM) are scarce and inconclusive. Furthermore, sTfR concentrations have been observed to be significantly higher in obese than in nonobese...

journal_title：European journal of clinical investigation

authors： Fernández-Cao JC,Arija V,Aranda N,Basora J,Diez-Espino J,Estruch R,Fitó M,Corella D,Salas-Salvadó J

更新日期：2017-03-01 00:00:00

abstract：:The effect of infusions of recombinant insulin-like growth factor-I (IGF-I) (34, 103 or 688 pmol min-1 kg-1), insulin (3.4, 10.3 or 68.8 pmol min-1 kg-1) or combined infusions (34 pmol IGF-I + 3.4 pmol min-1 kg-1 insulin or 103 pmol IGF-I + 3.4 pmol min-1 kg-1 insulin) on protein metabolism, using an infusion of [1-14...

journal_title：European journal of clinical investigation

authors： Umpleby AM,Shojaee-Moradie F,Thomason MJ,Kelly JM,Skottner A,Sonksen PH,Jones RH

更新日期：1994-05-01 00:00:00

abstract：:The in situ intraperitoneal volume and the mass transfer area coefficients (MTC) of urea, lactate, creatinine, glucose, kanamycin, inulin, beta 2-microglobulin, albumin and IgG were studied in eight continuous ambulatory peritoneal dialysis (CAPD) patients. All patients were studied during a 4-h dialysis dwell, first ...

journal_title：European journal of clinical investigation

authors： Krediet RT,Zuyderhoudt FM,Boeschoten EW,Arisz L

更新日期：1987-02-01 00:00:00

abstract：:Dipyrone metabolites 4-methylaminoantipyrine (MAA) and 4-formylaminoantipyrine (FAA) as well as acetylsalicylic acid inhibited neutrophil migration toward zymosan-activated serum. Inhibition was maximal (76.8 +/- 19.0; 79.2 +/- 12.5 and 80.0 +/- 4.4%, respectively, P less than 0.003) when suboptimal concentrations (0....

journal_title：European journal of clinical investigation

authors： Matzner Y,Drexler R,Levy M

更新日期：1984-12-01 00:00:00