Postnatal increase of procalcitonin in premature newborns is enhanced by chorioamnionitis and neonatal sepsis.

abstract：BACKGROUND:Memory and cognitive functions are known to decline with advancing age. Studies have suggested that this may be due to a decrease in cholinergic function in the brains of elderly people. This review aims to assess studies documented in the literature dealing with the 'scopolamine model' of dementia. METHODS...

journal_title：European journal of clinical investigation

authors： Ebert U,Kirch W

更新日期：1998-11-01 00:00:00

abstract：OBJECTIVE:N(ε)-(carboxymethyl)lysine (CML) is one of the major advanced glycation end products in both diabetics and nondiabetics. CML depositions in the microvasculature have recently been linked to the aetiology of acute myocardial infarction and cognitive impairment in Alzheimer's disease, possibly related to local ...

journal_title：European journal of clinical investigation

authors： Fuijkschot WW,de Graaff HJ,Berishvili E,Kakabadze Z,Kupreishvili K,Meinster E,Houtman M,van Broekhoven A,Schalkwijk CG,Vonk AB,Krijnen PA,Smulders YM,Niessen HW

更新日期：2016-04-01 00:00:00

abstract：:A significant rise in serum concentrations of aluminum was demonstrated in 23 patients prophylactically treated with the antacid magaldrate, whereas no increase in serum aluminium was observed in another 26 critically ill patients, in whom the use of antacids was avoided. In parallel, urinary excretion rates of alumin...

journal_title：European journal of clinical investigation

authors： Ittel TH,Gladziwa U,Mück W,Sieberth HG

更新日期：1991-02-01 00:00:00

abstract：BACKGROUND:Blocking the renin-angiotensin system (RAS) with angiotensin receptor blockers or angiotensin-converting enzyme inhibitors protects against renal injury in patients with chronic kidney disease (CKD). The aim of this study was to compare the chronic effects of telmisartan and enalapril on proteinuria, urinary...

journal_title：European journal of clinical investigation

authors： Nakamura T,Fujiwara N,Kawagoe Y,Sugaya T,Ueda Y,Koide H

更新日期：2010-09-01 00:00:00

abstract：:Infusion of ethanol (0.6 g/kg body wt) caused marked hypoglycaemia in subjects fasted for 36 h. Previous administration of the alcohol dehydrogenase (ADH) inhibitor 4-methylpyrazole (4-MP, 7 mg/kg body wt i.v.) strongly suppressed the ethanol-induced hypoglycaemia. The rate of ethanol elimination was 84.6 mg/kg per ho...

journal_title：European journal of clinical investigation

authors： Salaspuro MP,Pikkarainen P,Lindros K

更新日期：1977-12-01 00:00:00

abstract：BACKGROUND:Vitamin E supplementation is associated with a reduced risk of developing atherosclerotic events; probably because it inhibits low-density lipoprotein (LDL) oxidation, an initial step in atherosclerosis. Metal ion-dependent LDL oxidation is a commonly used method to estimate oxidizability of LDL, but the eff...

journal_title：European journal of clinical investigation

authors： Wen Y,Killalea S,Norris LA,Cooke T,Feely J

更新日期：1999-12-01 00:00:00

abstract：:The change in bone mass during 1 1/2 years was determined in a longitudinal study of sixty adult insulin-treated diabetic out-patients. During the study period the mean bone mass decreased by 1.30 +/- 0.28 (SEM)% (P less than 0.001), to a mean value of 91.0 +/- 1.7% of normal (P less than 0.001). The rate of bone loss...

journal_title：European journal of clinical investigation

authors： McNair P,Christiansen C,Christensen MS,Madsbad S,Faber OK,Binder C,Transbøl I

更新日期：1981-02-01 00:00:00

abstract：:The effect of sequential combined hormone replacement therapy on the susceptibility of low-density lipoprotein to oxidative modification was investigated in a double-blind, randomized placebo-controlled study. Hypercholesterolaemic, postmenopausal women were supplemented with 17 beta-oestradiol and norethisterone acet...

journal_title：European journal of clinical investigation

authors： Nenseter MS,Volden V,Berg T,Drevon CA,Ose L,Tonstad S

更新日期：1996-12-01 00:00:00

abstract：:The work was designed to study the effects of a meat meal on glomerular filtration rate (GFR), renal plasma flow (RPF), and plasma concentrations of glucagon, insulin, growth hormone, renin, aldosterone, total amino acids, and NH3 in healthy humans (H) as well as in patients with Child A liver cirrhosis (LC). The meat...

journal_title：European journal of clinical investigation

authors： De Santo NG,Anastasio P,Loguercio C,del Vecchio Blanco C,Capasso G,Coppola S,Bellini L,Spagnuolo G,Federico P,Alfieri R

更新日期：1992-01-01 00:00:00

abstract：BACKGROUND:During COVID-19 outbreak, oncological care has been reorganized. Patients with cancer have been reported to experience a more severe COVID-19 syndrome; moreover, there are concerns of a potential interference between immune checkpoint inhibitors (ICIs) and SARS-CoV-2 pathogenesis. MATERIALS AND METHODS:Betw...

journal_title：European journal of clinical investigation

authors： Tagliamento M,Spagnolo F,Poggio F,Soldato D,Conte B,Ruelle T,Barisione E,De Maria A,Del Mastro L,Di Maio M,Lambertini M

更新日期：2020-09-01 00:00:00

abstract：BACKGROUND:Passive smoking is a well-known risk factor for both recurrent respiratory infections and disturbed lipid profile. Whether passive smoking problems are related to altered lymphocyte survival and its relation to altered lipid profile are the points of concern in this work. MATERIALS AND METHODS:Urinary cotin...

journal_title：European journal of clinical investigation

authors： El-Hodhod MA,Hamdy AM,Ahmed MB,Youssef SR,Aly SM

更新日期：2011-04-01 00:00:00

abstract：:Moderate and progressive hypertension was produced experimentally in rats by progressive aortic constriction. The progression of the stenosis was assessed by the differences of pressure across the stenosis. Haemodynamic studies were performed 15, 30 and 60 days after the ligature was placed or after sham operation. Fi...

journal_title：European journal of clinical investigation

authors： Martín-Paredero V,Casado S,López-Novoa JM

更新日期：1984-08-01 00:00:00

abstract：:Transfers or exchanges of cholesterol esters and triglycerides between lipoproteins are mediated by a specialized protein referred to as cholesteryl ester transfer protein (CETP), whereas those of phospholipids (PLs) are facilitated by both CETP and a specific phospholipid transfer protein (PLTP). In the present study...

journal_title：European journal of clinical investigation

authors： Elchebly M,Pulcini T,Porokhov B,Berthezene F,Ponsin G

更新日期：1996-03-01 00:00:00

abstract：BACKGROUND:Plasmacytoid dendritic cells (pDCs) are multifunctional bone-marrow-derived immune cells that are key players in bridging the innate and adaptive immune systems. Activation of pDCs through toll-like receptor agonists has proven to be an effective treatment for some neoplastic disorders. MATERIALS AND METHOD...

journal_title：European journal of clinical investigation

authors： Lombardi VC,Khaiboullina SF,Rizvanov AA

更新日期：2015-01-01 00:00:00

abstract：:Whether leptin levels are related to insulin sensitivity or subject to acute regulation by insulin is not known. In 12 obese [body mass index (BMI) = 34.0 +/- 1.5 kg m-2] and 12 lean (BMI = 22.2 +/- 0.6 kg m-2) non-diabetic subjects, plasma leptin concentrations were measured in the fasting state and during 2 hours of...

journal_title：European journal of clinical investigation

authors： Muscelli E,Camastra S,Masoni A,Baldi S,Sironi AM,Natali A,Ferrannini E

更新日期：1996-10-01 00:00:00

abstract：BACKGROUND:Portal endotoxaemia has been speculated to be crucially involved in the pathogenesis of chronic hepatic inflammation, which is highly associated with the development of type 2 diabetes mellitus. This study tests whether portal endotoxaemia is a pathogenic link between chronic subacute hepatic inflammation an...

journal_title：European journal of clinical investigation

authors： Hsieh PS,Chan JY,Shyu JF,Chen YT,Loh CH

更新日期：2008-09-01 00:00:00

abstract：BACKGROUND:The mammalian target of rapamycin (mTOR) has recently been implicated in leukaemic cell growth, tumour-associated angiogenesis and expression of vascular endothelial growth factor (VEGF). We examined whether mTOR plays a role as regulator of growth and VEGF-expression in acute myeloid leukaemia (AML). Three ...

journal_title：European journal of clinical investigation

authors： Böhm A,Aichberger KJ,Mayerhofer M,Herrmann H,Florian S,Krauth MT,Derdak S,Samorapoompichit P,Sonneck K,Vales A,Gleixner KV,Pickl WF,Sperr WR,Valent P

更新日期：2009-05-01 00:00:00

abstract：OBJECTIVES:EPB4.1 has been previously mapped to human chromosome 1p33-p34.2. In contradiction to this chromosomal location, we have mapped EPB4.1-1p36 by using fluorescence in situ hybridization and radiation hybrid mapping. In neuroblastomas, deletions of the telomeric end of chromosome 1 (1p36) are the most common ge...

journal_title：European journal of clinical investigation

authors： Huang S,Lichtenauer UD,Pack S,Wang C,Kim AC,Lutchman M,Koch CA,Torres-Cruz J,Huang SC,Benz EJ Jr,Christiansen H,Dockhorn-Dworniczak B,Poremba C,Vortmeyer AO,Chishti AH,Zhuang Z

更新日期：2001-10-01 00:00:00

abstract：BACKGROUND:HFE knockout mice (C57BL/6 x 129/Ola strain) mimic the functional aberrations of human hereditary haemochromatosis (HH) in short-term experiments. The present study investigates functional and morphological long-term changes. METHODS:HFE(o/o), HFE(+/o) and HFE(+/+) mice were maintained on iron-rich and cont...

journal_title：European journal of clinical investigation

authors： Lebeau A,Frank J,Biesalski HK,Weiss G,Srai SK,Simpson RJ,McKie AT,Bahram S,Gilfillan S,Schümann K

更新日期：2002-08-01 00:00:00

abstract：:To understand better impairment of glucose utilization in diabetics during a hyperosmolal state, in vitro models were established to evaluate the effects of hyperosmolality on basal glucose uptake as well as glucagon dependent glucose release by isolated hepatocytes. In these studies simulating a hyperglycaemic (40 mm...

journal_title：European journal of clinical investigation

authors： Komjati M,Kastner G,Waldhäusl W,Bratusch-Marrain P

更新日期：1989-04-01 00:00:00

abstract：:In order to estimate their in-vivo reactivity two antacids of equal theoretical neutralizing capacity (approximately 3.9 mol/l at pH 3.5) but of different chemical composition were employed as intragastric titrant (pH 3.5) following a liquid protein meal (oxo) in two groups of five volunteers each. The two antacids ch...

journal_title：European journal of clinical investigation

authors： Halter F,Huber R,Häcki WH,Varga L,Bachmann C

更新日期：1982-06-01 00:00:00

abstract：BACKGROUND:Abscess formation is a common bacterial infection and requires an immediate antimicrobial approach for apposite treatment. Delay in patient treatment is usually a common feature, as the bacterial identification of clinical samples is based on the culture, which is a time-consuming exercise. The current study...

journal_title：European journal of clinical investigation

authors： Garg M,Misra MK,Chawla S,Prasad KN,Roy R,Gupta RK

更新日期：2003-06-01 00:00:00

abstract：:Three different types of cardiovascular sequelae attributed to interferon therapy have been reported: arrhythmia, ischaemic heart disease and cardiomyopathy. We evaluated the left ventricular ejection fraction (LVEF) during alpha interferon therapy (3 MU administered subcutaneously three times a week for 6 months) in ...

journal_title：European journal of clinical investigation

authors： Sartori M,Andorno S,La Terra G,Pozzoli G,Rudoni M,Sacchetti GM,Inglese E,Aglietta M

更新日期：1995-01-01 00:00:00

abstract：:The aim of the study was to compare the changes in plasma renin activity induced by a vasodilator in normal dogs and in dogs with an impaired cardiac reserve. In normal conscious dogs, a 60-min nitroprusside infusion increased plasma renin activity from 1.05 +/- 0.26 to 8.35 +/- 1.20 ng, angiotensin I ml-1 h-1 (P less...

journal_title：European journal of clinical investigation

authors： Pouleur H,Engler RL,Link J,Printz MP,Covell JW

更新日期：1983-08-01 00:00:00

abstract：BACKGROUND:High levels of circulating cell-free DNA (cfDNA) have been reported in patients with inflammatory conditions. The aim of the study was to investigate the levels of cfDNA in patients with systemic lupus erythematosus (SLE). MATERIALS AND METHODS:Comparative groups comprised 22 nonpregnant and 36 pregnant wom...

journal_title：European journal of clinical investigation

authors： Xu Y,Song Y,Chang J,Zhou X,Qi Q,Tian X,Li M,Zeng X,Xu M,Zhang W,Cram DS,Liu J

更新日期：2018-11-01 00:00:00

abstract：BACKGROUND:Based on a report of a marked increase in the erythropoietin concentration ([EPO]) a few hours after the cessation of a single 2-h session of O(2) breathing, short periods of O(2) administration have been advocated as a therapy for anaemia. Accordingly, the purpose of the present study was to evaluate this t...

journal_title：European journal of clinical investigation

authors： Keramidas ME,Norman B,Gustafsson T,Eiken O,Mekjavic IB

更新日期：2012-03-01 00:00:00

abstract：:Deficiency of apolipoprotein C-II (apo C-II), the cofactor for lipoprotein lipase, results in the familial chylomicronaemia syndrome characterized by severe hypertriglyceridaemia and fasting chylomicronaemia. To investigate the biochemical features of the heterozygous state for apo C-II deficiency, we characterized th...

journal_title：European journal of clinical investigation

authors： Gabelli C,Bilato C,Santamarina-Fojo S,Martini S,Brewer HB Jr,Crepaldi G,Baggio G

更新日期：1993-09-01 00:00:00

abstract：:Serum prolactin levels were measured by radioimmunoassay in eighty patients (thirty-four males, forty-six females) with sarcoidosis before treatment. In twelve patients (15%) serum prolactin levels were more than two standard deviations above the mean of normal subjects. Hyperprolactinaemia was found most frequently (...

journal_title：European journal of clinical investigation

authors： Nakao K,Noma K,Sato B,Yano S,Yamamura Y,Tachibana T

更新日期：1978-02-01 00:00:00

abstract：BACKGROUND:A broad spectrum of hepatobiliary disorders are found in patients with inflammatory bowel diseases. The aim of the present work was to study interactions between gut and liver in experimental rat models of colitis and small bowel inflammation. MATERIALS AND METHODS:Colitis was induced either by trinitrobenz...

journal_title：European journal of clinical investigation

authors： Dikopoulos N,Schmid RM,Bachem M,Buttenschoen K,Adler G,Chiang JY,Weidenbach H

更新日期：2007-03-01 00:00:00

abstract：BACKGROUND:Chronic kidney disease (CKD) exacerbates the risk of death due to cardiovascular disease (CVD). Modifications to blood lipid metabolism which manifest as increases in circulating triglycerides and reductions in high-density lipoprotein (HDL) cholesterol are thought to contribute to increased risk. In CKD pat...

journal_title：European journal of clinical investigation

authors： Brinck JW,Thomas A,Brulhart-Meynet MC,Lauer E,Frej C,Dahlbäck B,Stenvinkel P,James RW,Frias MA

更新日期：2018-02-01 00:00:00