Gastrointestinal permeability to polyethylene glycol: an evaluation of urinary recovery of an oral load of polyethylene glycol as a parameter of intestinal permeability in man.

abstract：:The pregnancies of two patients with mild intrahepatic cholestasis of pregnancy (RCP) were followed with detailed analyses of bile acids in urine. About twenty-five different bile acids were determined by GC/MS following separation according to mode of conjugation. The results were collated with the clinical course of...

journal_title：European journal of clinical investigation

authors： Thomassen PA

更新日期：1979-12-01 00:00:00

abstract：:A kindred in which several members have otherwise typical acute intermittent porphyria but normal erythrocyte uroporphyrinogen-I-synthase activity has been described from Finland. We studied two porphyric members of this kindred, two patients with typical acute intermittent porphyria, and two healthy controls using th...

journal_title：European journal of clinical investigation

authors： Mustajoki P,Tenhunen R

更新日期：1985-10-01 00:00:00

abstract：:The relationship between serum levels of lipoprotein(a) Lp(a)) and the presence of chronic diabetic complications was studied in 194 patients with non-insulin-dependent diabetes mellitus (NIDDM; 75 males, 119 females; age 66 +/- 11 years; duration of diabetes, 11 (range 1-35) years). They were taking various treatment...

journal_title：European journal of clinical investigation

authors： Heesen BJ,Wolffenbuttel BH,Leurs PB,Sels JP,Menheere PP,Jäckle-Beckers SE,Nieuwenhuijzen Kruseman AC

更新日期：1993-09-01 00:00:00

abstract：:The effects of glucose on the cytoplasmic Ca2+ concentration (Ca2+i) regulating insulin release were investigated using pancreatic beta-cells representative for the normal and diabetic situations. Increase of the glucose concentration resulted in a slight lowering of Ca2+i followed by a rise, often manifested as high ...

journal_title：European journal of clinical investigation

authors： Hellman B,Berne C,Grapengiesser E,Grill V,Gylfe E,Lund PE

更新日期：1990-10-01 00:00:00

abstract：:Changes in blood glucose homeostasis induced by the new somatostatin analogue BIM 23014 (BIM) were studied. Eight normal men (study 1) received either vehicle or 1000, 2000 and 3000 micrograms BIM as a 24 h s.c. infusion. Blood glucose, plasma insulin, C-peptide, glucagon and growth hormone (GH) were measured before t...

journal_title：European journal of clinical investigation

authors： Kuhn JM,Basin C,Mollard M,De Rouge B,Schatz B,Wolf LM

更新日期：1992-12-01 00:00:00

abstract：BACKGROUND:There is growing evidence that the predictive value of HDL cholesterol levels for cardiovascular risk stratification is limited in patients with coronary artery disease (CAD). HDL function seems to be a more sensitive surrogate of cardiovascular risk estimation than simple serum levels. Therefore, we aimed t...

journal_title：European journal of clinical investigation

authors： Distelmaier K,Wiesbauer F,Blessberger H,Oravec S,Schrutka L,Binder C,Dostal E,Schillinger M,Wojta J,Lang IM,Maurer G,Huber K,Goliasch G

更新日期：2015-07-01 00:00:00

abstract：BACKGROUND:Humming greatly increases nasal nitric oxide (NO) in healthy people by causing a rapid washout of NO from the sinuses. This increase is abolished in patients with complete sinus ostial obstruction. OBJECTIVE:Allergic rhinitis is a risk factor for development of sinusitis and we wanted to study whether nasal...

journal_title：European journal of clinical investigation

authors： Maniscalco M,Sofia M,Weitzberg E,De Laurentiis G,Stanziola A,Rossillo V,Lundberg JO

更新日期：2004-08-01 00:00:00

abstract：BACKGROUND:Augmentation index (AIx) is a measure of arterial wave reflection, providing information on the workload of the heart. and is a possible marker for cardiovascular disease risk. The relation of alcohol consumption with cardiovascular disease (CVD) risk is U-shaped with a protective effect of moderate alcohol ...

journal_title：European journal of clinical investigation

authors： van Trijp MJ,Bos WJ,van der Schouw YT,Muller M,Grobbee DE,Bots ML

更新日期：2005-10-01 00:00:00

abstract：:Arterial lumen narrowing and vascular occlusion is the actual cause of morbidity and mortality in atherosclerotic disease. Collateral artery formation (arteriogenesis) refers to an active remodelling of non-functional vascular anastomoses to functional collateral arteries, capable to bypass the site of obstruction and...

journal_title：European journal of clinical investigation

authors： de Groot D,Pasterkamp G,Hoefer IE

更新日期：2009-12-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to compare the prevalence of lumbar spondylolisthesis (SPL) in patients suffering from low back pain (LBP) with or without rheumatoid arthritis (RA) and to identify potential factors associated with SPL in patients with RA. METHODS:We performed a case-control study. Cases and contro...

journal_title：European journal of clinical investigation

authors： Hagege B,Tubach F,Alfaiate T,Forien M,Dieudé P,Ottaviani S

更新日期：2018-09-01 00:00:00

abstract：:We measured plasma sulphur amino acids in twenty-two patients with chronic renal failure and compared the findings with those obtained in twenty-two normal subjects. In fasting blood (08.00 hours) cysteine-homocysteine mixed disulphide was significantly increased in the renal patients, mean values (+/- SD) being 8.2 +...

journal_title：European journal of clinical investigation

authors： Wilcken DE,Gupta VJ

更新日期：1979-08-01 00:00:00

abstract：:In order to study the mechanisms by which nutrients influence post-trauma metabolism, Sprague-Dawley rats received a 25% full-thickness burn and were randomly assigned to receive 12.5 g kg-1 bodyweight (BW) per day amino acids (AA) only, AA and 14.7 g hydrous glucose kg-1 BW per day or AA and 14.7 g hydrous xylitol kg...

journal_title：European journal of clinical investigation

authors： Georgieff M,Pscheidl E,Moldawer LL,Bistrian BR,Blackburn GL

更新日期：1991-04-01 00:00:00

abstract：BACKGROUND:Postpericardiotomy syndrome (PPS) is a common complication following cardiac surgery; however, the exact pathogenesis remains uncertain. Identifying risk factors of PPS might help to better understand the syndrome. The aim of this study was to provide an overview of existing literature around determinants of...

journal_title：European journal of clinical investigation

authors： van Osch D,Nathoe HM,Jacob KA,Doevendans PA,van Dijk D,Suyker WJ,Dieleman JM

更新日期：2017-06-01 00:00:00

abstract：BACKGROUND:Stiff Person Syndrome (SPS) is a relatively rare but often overlooked autoimmune neurological disorder that targets antigens within the brain's inhibitory pathways resulting in incapacitating stiffness and spasms that impact on the patients' quality of life. Although a number of immunomodulating therapies si...

journal_title：European journal of clinical investigation

authors： Alexopoulos H,Dalakas MC

更新日期：2010-11-01 00:00:00

abstract：BACKGROUND:Following cisplatin-based chemotherapy, survivors of testicular cancer have a high prevalence of cardiovascular risk factors and an increased risk of cardiovascular disease. Cardiac function has not been extensively studied and no comparisons have been made with men from the general population. DESIGN:Left ...

journal_title：European journal of clinical investigation

authors： Nuver J,Smit AJ,Sleijfer DT,van Gessel AI,van Roon AM,van der Meer J,van den Berg MP,Hoekstra HJ,Sluiter WJ,Gietema JA

更新日期：2005-02-01 00:00:00

abstract：:The impact of running and menstrual disturbances on regional and total body fat distribution and serum lipids was investigated in 205 women. Body composition was measured by dual-energy X-ray absorptiometry. The total fat mass in the elite runners was approximately half of the normally active's (7.3 [0.48] kg vs. 14.3...

journal_title：European journal of clinical investigation

authors： Hetland ML,Haarbo J,Christiansen C

更新日期：1995-08-01 00:00:00

abstract：:Primary biliary cirrhosis and primary sclerosing cholangitis are well recognized chronic cholestatic liver diseases that are considered to have an autoimmune basis. Recent progress in the study of autoimmune liver diseases has improved the recognition and characterization of these conditions. An important component of...

journal_title：European journal of clinical investigation

authors： Medina J,Jones EA,García-Monzón C,Moreno-Otero R

更新日期：2001-01-01 00:00:00

abstract：BACKGROUND:Little is known about gallbladder motility in patients with black pigment stones when compared to cholesterol gallstone patients, or about their relationship to biliary composition, crystallization and stone characteristics. DESIGN:Fasting and postprandial gallbladder volumes were studied by ultrasonography...

journal_title：European journal of clinical investigation

authors： Portincasa P,Di Ciaula A,Vendemiale G,Palmieri V,Moschetta A,Vanberge-Henegouwen GP,Palasciano G

更新日期：2000-04-01 00:00:00

abstract：BACKGROUND:Insulin resistance significantly correlated with a non-dipper type of essential hypertension. Thiazolidinediones (TZD), oral hypoglycaemic agents that act as insulin sensitizers, have been demonstrated in multiple in vivo and in vitro studies to possess antihypertensive properties. This study examined the ef...

journal_title：European journal of clinical investigation

authors： Anan F,Masaki T,Fukunaga N,Teshima Y,Iwao T,Kaneda K,Umeno Y,Okada K,Wakasugi K,Yonemochi H,Eshima N,Saikawa T,Yoshimatsu H

更新日期：2007-09-01 00:00:00

abstract：BACKGROUND:Improvement of renal concentration capacity was long ago shown to occur after surgery for primary hyperparathyroidism (pHPT). Study of concentration capacity is of interest, as it was also shown to be a predictive factor for the risk of death in patients with pHPT, and it affected the risk of death independe...

journal_title：European journal of clinical investigation

authors： Hedbäck G,Abrahamsson K,Odén A

更新日期：2001-12-01 00:00:00

abstract：BACKGROUND:Alzheimer's disease (AD) is an age-related neurodegenerative disorder that is characterized by a progressive loss of higher cognitive functions. The brain of an individual with AD exhibits extracellular senile plaques (SPs) of aggregated amyloid-beta peptide (Abeta) and intracellular neurofibrillary tangles ...

journal_title：European journal of clinical investigation

authors： Yokota T,Mishra M,Akatsu H,Tani Y,Miyauchi T,Yamamoto T,Kosaka K,Nagai Y,Sawada T,Heese K

更新日期：2006-11-01 00:00:00

abstract：:Fibromuscular dysplasia (FMD) is an idiopathic, segmental, non-atherosclerotic and non-inflammatory disease of the musculature of arterial walls, leading to stenosis of small and medium-sized arteries, mostly involving renal and cervical arteries. As a result of better and more systematic screening, it appears that in...

journal_title：European journal of clinical investigation

authors： Van der Niepen P,van Tussenbroek F,Devos H,Debing E,Di Monaco S,Goffette P,Astarci P,Persu A

更新日期：2018-11-01 00:00:00

abstract：:It has been shown that the detection of tuberculostearic acid (TBSA) with gas chromatography-mass-spectrometry provides a highly specific, sensitive and rapid method for the diagnosis of various forms of tuberculosis. However, the need for complex and expensive equipment prevented the more widespread use of this metho...

journal_title：European journal of clinical investigation

authors： Herz A,Leichsenring M,Felten M,Oosthuizen OJ,Mayatepek E,Haas W,Bremer HJ

更新日期：1994-02-01 00:00:00

abstract：:Acute renal failure is a grave complication of systemic gram-negative sepsis. The pathophysiological mechanisms of sepsis leading to kidney injury result in part from systemic inflammatory and haemodynamic alterations. These are triggered by the interaction of endotoxin with Toll-like receptor 4 (TLR4) on cells of the...

journal_title：European journal of clinical investigation

authors： El-Achkar TM,Hosein M,Dagher PC

更新日期：2008-10-01 00:00:00

abstract：BACKGROUND:Buerger's disease (BD) is a segmental occlusive vascular disease. The aim of this study was to detect functional changes in brachial artery and asymptomatic morphological changes in extra-cranial carotid arteries not affected by the disease process and to assess markers of inflammation and endothelial damage...

journal_title：European journal of clinical investigation

authors： Joras M,Poredos P,Fras Z

更新日期：2006-06-01 00:00:00

abstract：:The aim of this research was to study exogenous prostacyclin effect on urinary kallikrein excretion (UKK) in man, to define whether prostacyclin-induced renin release and/or endogenously released cyclooxygenase products were responsible for prostacyclin-induced enhancement of UKK, to determine furosemide effect on UKK...

journal_title：European journal of clinical investigation

authors： Pierucci A,Simonetti BM,Ciabattoni G,Taggi F,Morabito S,Vastano S,Pugliese F

更新日期：1986-06-01 00:00:00

abstract：:This study focuses on the role of platelet membrane glycoproteins and platelet-leucocyte adhesion in patients with sepsis and multiple organ failure (MOF). Specifically, the study raises the following issues: (1) the influence of sepsis and MOF on platelet activation as assessed by surface expression of platelet membr...

journal_title：European journal of clinical investigation

authors： Gawaz M,Fateh-Moghadam S,Pilz G,Gurland HJ,Werdan K

更新日期：1995-11-01 00:00:00

abstract：:Eur J Clin Invest 2012; 42 (6): 579-588 ABSTRACT: Glucose-based methods are currently gold standards for identifying individuals at risk of type 2 diabetes. Obviously, these methods only consider one of many pathologies of impaired glucose metabolism and they all suffer from a poor specificity as type 2 diabetes risk ...

journal_title：European journal of clinical investigation

authors： Gjesing AP,Pedersen O

更新日期：2012-06-01 00:00:00

abstract：BACKGROUND:Studies in different animal models and plasma analyses in humans suggest that members of the interleukin-6 (IL-6) cytokine family may be involved in the pathogenesis of congestive heart failure (CHF). Accordingly, we have examined IL-6-related cytokines in chronic CHF in humans by analysing gene and protein ...

journal_title：European journal of clinical investigation

authors： Eiken HG,Øie E,Damås JK,Yndestad A,Bjerkeli V,Aass H,Simonsen S,Geiran OR,Tønnessen T,Christensen G,Frøland SS,Gullestad L,Attramadal H,Aukrust P

更新日期：2001-05-01 00:00:00

abstract：:The study aimed to assess vascular reactivity to noradrenaline with and without neuropeptide Y in diabetic rats, and to determine whether any abnormality could be attributed to insulin deficiency or to hyperglycaemia per se. The authors compared non-diabetic rats (n = 9) and rats with streptozotocin-induced diabetes t...

journal_title：European journal of clinical investigation

authors： Savage MW,Bodmer CW,Walker AB,Buchan IE,Masson EA,Williams G

更新日期：1995-12-01 00:00:00