Alcohol and arterial wave reflections in middle aged and elderly men.

abstract：:Urine was collected in four healthy infants, born after 35-39 weeks of gestation. The collections were made for 24 h starting immediately after birth. Bile acids were extracted, separated into conjugate groups, solvolysed, hydrolysed and quantified by gas-liquid chromatography as methyl ester trimethylsilyl ether deri...

journal_title：European journal of clinical investigation

authors： Strandvik B,Wikström SA

更新日期：1982-08-01 00:00:00

abstract：:The mucosal incorporation and clearance of a DNA precursor was examined in the rat stomach and intestine following oral treatment with natural prostaglandin E2 (PGE2) or 15(R) 15 methyl prostaglandin E2 (Me PGE2). Control groups received vehicle or pentagastrin. After five days of treatment animals were labelled with ...

journal_title：European journal of clinical investigation

authors： Johansson C,Uribe A,Rubio C,Isenberg JI

更新日期：1986-12-01 00:00:00

abstract：:The effect of marine n-3 polyunsaturated fatty acids on proliferation of human T-cells in vitro was compared to other polyunsaturated, monounsaturated and saturated fatty acids. Monoenes and saturated fatty acids had little effect on T-cell proliferation. Eicosapentaenoic acid and docosahexaenoic acid exerted a strong...

journal_title：European journal of clinical investigation

authors： Søyland E,Nenseter MS,Braathen L,Drevon CA

更新日期：1993-02-01 00:00:00

abstract：BACKGROUND:There is an ongoing debate on a potential protective role of habitual physical activity and passive heat therapy on the risk of COVID-19, a respiratory infectious disease that can manifest as severe pneumonia. To explore these putative roles, we evaluated the independent and joint associations of cardiorespi...

journal_title：European journal of clinical investigation

authors： Kunutsor SK,Laukkanen JA

更新日期：2021-01-10 00:00:00

abstract：:We have examined the impact of race and positive family history of type 2 diabetes on glucose/insulin dynamics and the two components of glucose disposal in healthy, first-degree relatives of black and white American patients with type 2 diabetes mellitus who are at a greater risk from the disease and their healthy co...

journal_title：European journal of clinical investigation

authors： Osei K,Cottrell DA

更新日期：1994-12-01 00:00:00

abstract：:The saphenous vein is the most commonly used graft for revascularization procedures in patients with coronary artery disease and critical limb ischaemia. However, the patency rate of this vessel is poor, with a high proportion of patients requiring further surgery. Early graft occlusion is caused by vasoconstriction o...

journal_title：European journal of clinical investigation

authors： Dashwood MR

更新日期：2009-06-01 00:00:00

abstract：BACKGROUND:Morpholinosydnonimine, a nitric oxide (NO) donor, has been reported to inhibit insulin release in isolated pancreatic islets. We studied whether transdermal application of nitroglycerin, another NO donor widely used for angina prophylaxis, influenced glucose-stimulated insulin release in healthy, young, male...

journal_title：European journal of clinical investigation

authors： Kovacs P,Szilvassy Z,Hegyi P,Nemeth J,Ferdinandy P,Tosaki A

更新日期：2000-01-01 00:00:00

abstract：:Polyploidization is a distinctive feature of megakaryocyte differentiation. The physiological meaning and the regulation of this process are obscure. Megakaryocyte ploidy varies in normal biology and in disease. Here we review the evidence suggesting that ploidy changes may have a role in the determination of platelet...

journal_title：European journal of clinical investigation

authors： Erusalimsky JD,Martin JF

更新日期：1993-01-01 00:00:00

abstract：:Pepsinogen A (PGA) and pepsinogen C (PGC) are negatively charged, low molecular weight (LMW) proteins with a striking difference in renal handling: PGA (molecular weight 43,500 daltons) shows a high fractional excretion while the fractional excretion of PGC (molecular weight 40,500 daltons) is low, presumably due to t...

journal_title：European journal of clinical investigation

authors： ten Kate RW,Pals G,Res JC,van Kamp GJ,Verheugt FW,Pronk JC,Donker AJ,Eriksson AW,Meuwissen SG

更新日期：1989-06-01 00:00:00

abstract：:The release of PGI2-like activity into the circulation in response to cholinergic agonists and modification of this response by beta-adrenergic antagonists was investigated in anaesthetized cats and healthy humans. Antiaggregatory activity in the arterial blood was continuously assayed by measuring platelet aggregatio...

journal_title：European journal of clinical investigation

authors： Swies J,Radomski M,Dembińska-Kieć A,Korbut R,Gryglewski RJ,Brandt R,Nowak J

更新日期：1985-12-01 00:00:00

abstract：BACKGROUND:Gastroesophageal reflux disease (GERD), including erosive reflux disease and non-erosive reflux disease (NERD), is a chronic disease with a significant negative effect on quality of life. State-of-the-art treatment involves proton pump inhibitors (PPIs). However, relapse of symptoms occurs in the majority of...

journal_title：European journal of clinical investigation

authors： Compare D,Pica L,Rocco A,De Giorgi F,Cuomo R,Sarnelli G,Romano M,Nardone G

更新日期：2011-04-01 00:00:00

abstract：BACKGROUND:Urotensin II plays a role in myocardial remodelling. Cardiac fibroblasts play a critical role in the development of cardiac fibrosis. The effect of hypoxia on urotensin II expression in cardiac fibroblasts is poorly understood. We sought to investigate the regulation of urotensin II by hypoxia in cardiac fib...

journal_title：European journal of clinical investigation

authors： Shyu KG,Wang BW,Chen WJ,Kuan P,Lin CM

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:Childhood obesity is associated with premature cardiovascular complications. However, little is known about the effect of a family-based behavioural intervention on the relationship between arterial function, blood pressure and biomarkers in pre-pubertal children with obesity. DESIGN:This was a single centr...

journal_title：European journal of clinical investigation

authors： Maggio ABR,Farpour-Lambert NJ,Aggoun Y,Galan K,Montecucco F,Mach F,Beghetti M

更新日期：2018-09-01 00:00:00

abstract：:We present a sensitive time-resolved fluorometric immunofunctional assay (TR-FIA) for direct quantitation of functional growth hormone-binding protein (GHBP), using an immunoassay kit for growth hormone (GH-DELFIA). In addition to the immobilized GH antibody, one monoclonal antibody against GHBP was used. This anti-GH...

journal_title：European journal of clinical investigation

authors： Fisker S,Frystyk J,Skriver L,Vestbo E,Ho KK,Orskov H

更新日期：1996-09-01 00:00:00

abstract：BACKGROUND:Alcohol may have a cardioprotective effect. One possible mechanism is by modifying insulin resistance/secretion. The aims of this study were: (i) to examine the effect of short-term alcohol consumption on the metabolic control of glucose tolerance; (ii) to study the influence of short-term alcohol consumptio...

journal_title：European journal of clinical investigation

authors： Flanagan DE,Pratt E,Murphy J,Vaile JC,Petley GW,Godsland IF,Kerr D

更新日期：2002-03-01 00:00:00

abstract：:Assuming that lithium is exclusively reabsorbed in the proximal tubules pari passu with sodium (Na), the lithium clearance (CLi) has been advanced as an index of filtrate delivery from the proximal tubules. In order to determine whether water loads in a range commonly given during clearance studies affect CLi, we stud...

journal_title：European journal of clinical investigation

authors： Boer WH,Koomans HA,Dorhout Mees EJ

更新日期：1988-06-01 00:00:00

abstract：:Two methods of measurement of fractional calcium absorption have been compared in the same individuals. There is a significant correlation between fractional 47Ca absorption as measured with a blood counting method and with an external counting method after intravenous and oral administration of 47Ca (P less than 0.00...

journal_title：European journal of clinical investigation

authors： Juttmann JR,Ruis AM,Hagenouw-Taal JC,Lockefeer JH,Birkenhäger JC

更新日期：1978-06-01 00:00:00

abstract：:Plasma glucose concentration is the best predictor for the development of non-insulin-dependent diabetes mellitus (NIDDM). However, obesity is also a recognized risk factor for development of the disease, and is easier to track over time. Thus obesity could be of considerable clinical importance as a predictor of diab...

journal_title：European journal of clinical investigation

authors： Ferrannini E,Camastra S

更新日期：1998-09-01 00:00:00

abstract：BACKGROUND:Profilin-1 is a ubiquitous, actin-binding protein that plays an important role in the regulation of actin polymerization and cytoskeleton remodelling and contributes to vascular dysfunction. We conducted this study to investigate the association of serum profilin-1 levels with fatal and nonfatal CVE in a coh...

journal_title：European journal of clinical investigation

authors： Eroglu E,Unal HU,Guclu A,Kocyigit I,Karaman M,Saglam M,Gezer M,Tas A,Zararsiz G,Eyileten T,Aydin İ,Oguz Y,Gungor O,Yilmaz MI

更新日期：2017-12-01 00:00:00

abstract：BACKGROUND:Obstructive sleep apnoea (OSA) is a common complication of obesity and can have a substantial negative impact on a patient's quality of life and risk of cardiovascular disease. The aim of this case-control study was to undertake discovery profiling of urinary peptides using capillary electrophoresis-mass spe...

journal_title：European journal of clinical investigation

authors： Seetho IW,Siwy J,Albalat A,Mullen W,Mischak H,Parker RJ,Craig S,Duffy N,Hardy KJ,Burniston JG,Wilding JP

更新日期：2014-11-01 00:00:00

abstract：:Many diseases with a major public health impact are the result of complex interactions between environmental factors and multiple genes. In the past decade, methods for genome analysis, in particular quantitative trait locus (QTL) analysis in animal models, were developed to identify and localize the genes responsible...

journal_title：European journal of clinical investigation

authors： Hillebrandt S,Matern S,Lammert F

更新日期：2003-02-01 00:00:00

abstract：:Thirty-one patients with IgG antibodies to cardiolipin (ACLA) were studied to determine their in vivo formation of the platelet aggregating and vasoconstricting substance thromboxane A2 (TxA2) and the platelet inhibiting and vasodilating substance prostacyclin (PGI2). This was done by measurements in urine of their en...

journal_title：European journal of clinical investigation

authors： Arfors L,Vesterqvist O,Johnsson H,Gréen K

更新日期：1990-12-01 00:00:00

abstract：:The secretion of insulin and glucagon was investigated in pancreatic islets from diabetic and nondiabetic sand rats of similar age and weight. The metabolic characterization was based on an intraperitoneal glucose tolerance test. Compared to nondiabetic animals diabetic sand rats had a diminished insulin content in th...

journal_title：European journal of clinical investigation

authors： Hahn HJ,Schäfer H,Gottschling HD,Fiedler H

更新日期：1976-01-30 00:00:00

abstract：BACKGROUND:We have investigated the potential for using antisense technology as a means of delivering treatment for acute myeloblastic leukaemia (FAB-M2) by gene therapy. MATERIALS AND METHODS:A test recombinant adenovirus vector was constructed containing human c-myc antisense fragments to study the effects of alteri...

journal_title：European journal of clinical investigation

authors： Chen JP,Chen L,Leek J,Lin C

更新日期：2006-01-01 00:00:00

abstract：BACKGROUND:To compare the administration of furosemide with placebo on the subjective perception of dyspnoea in patients with acute pulmonary oedema because of hypertensive crisis. Design  Randomized, controlled and double-blinded clinical trial. SETTING:Municipal emergency medical service system and university-based ...

journal_title：European journal of clinical investigation

authors： Holzer-Richling N,Holzer M,Herkner H,Riedmüller E,Havel C,Kaff A,Malzer R,Schreiber W

更新日期：2011-06-01 00:00:00

abstract：:Antibodies against prostaglandins (PG)F2alpha, E1 and E2 were obtained inrabbits immunized with respectively PG F2alpha, PG E1 and PG E2 conjugated to bovine serum albumin by carbodiimide. A radioimmunoassay capable of measuring 7 pg of PG Falpha, 2 pg of PG E2 and 14 pg of PG E1 in human peripheral plasma is describe...

journal_title：European journal of clinical investigation

authors： Dray F,Charbonnel B,Maclouf J

更新日期：1975-07-29 00:00:00

abstract：BACKGROUND:Based on a report of a marked increase in the erythropoietin concentration ([EPO]) a few hours after the cessation of a single 2-h session of O(2) breathing, short periods of O(2) administration have been advocated as a therapy for anaemia. Accordingly, the purpose of the present study was to evaluate this t...

journal_title：European journal of clinical investigation

authors： Keramidas ME,Norman B,Gustafsson T,Eiken O,Mekjavic IB

更新日期：2012-03-01 00:00:00

abstract：:The effect of propranolol 160-640 mg/day for 3 months on the accelerated loss of bone matrix and mineral in hyperthyroidism was studied in seventeen patients. A rise in serum thyroxine (P less than 0.01) during the first 3 weeks was followed by a fall (P less than 0.02). Serum triiodothyronine declined during the stud...

journal_title：European journal of clinical investigation

authors： Mosekilde L,Jastrup B,Melsen F,Lund B,Lund B,Sørensen OH,Nielsen HE,Yde H

更新日期：1984-04-01 00:00:00

abstract：:Novel, powerful and long-acting inhibitors of gastric acid secretion include second generation H2-blockers and so-called proton pump inhibitors, such as omeprazole. Gastric carcinoids were found to develop in experimental animals as a consequence of continuous long-term administration of several of these highly effect...

journal_title：European journal of clinical investigation

authors： Håkanson R,Sundler F

更新日期：1990-10-01 00:00:00

abstract：:Infusion of ethanol (0.6 g/kg body wt) caused marked hypoglycaemia in subjects fasted for 36 h. Previous administration of the alcohol dehydrogenase (ADH) inhibitor 4-methylpyrazole (4-MP, 7 mg/kg body wt i.v.) strongly suppressed the ethanol-induced hypoglycaemia. The rate of ethanol elimination was 84.6 mg/kg per ho...

journal_title：European journal of clinical investigation

authors： Salaspuro MP,Pikkarainen P,Lindros K

更新日期：1977-12-01 00:00:00