Stimulatory cholinergic effect on the release of antiaggregatory activity into the circulation of cat and man and its modification by beta-adrenergic antagonists.

abstract：BACKGROUND:In inflammatory bowel diseases, changes in autonomic enteric regulation may also affect neural cardiovascular control. However, while cardiac autonomic modulation has been shown to be impaired in active ulcerative colitis, the occurrence of cardiovascular autonomic alterations, also in the quiescent phase of...

journal_title：European journal of clinical investigation

authors： Coruzzi P,Castiglioni P,Parati G,Brambilla V,Brambilla L,Gualerzi M,Cademartiri F,Franzè A,De Angelis G,Di Rienzo M,Di Mario F

更新日期：2007-12-01 00:00:00

abstract：:Primary biliary cirrhosis and primary sclerosing cholangitis are well recognized chronic cholestatic liver diseases that are considered to have an autoimmune basis. Recent progress in the study of autoimmune liver diseases has improved the recognition and characterization of these conditions. An important component of...

journal_title：European journal of clinical investigation

authors： Medina J,Jones EA,García-Monzón C,Moreno-Otero R

更新日期：2001-01-01 00:00:00

abstract：BACKGROUND:Right ventricular (RV) dysfunction in heart failure (HF) with reduced left ventricular ejection fraction (LVEF) is associated with a poorer prognosis. No studies to date have investigated the prognostic utility of RV isovolumic acceleration (IVA) measured at tissue Doppler imaging (TDI) in HF. RV strain inst...

journal_title：European journal of clinical investigation

authors： Sciatti E,Vizzardi E,Bonadei I,Curnis A,D'Aloia A,Metra M

更新日期：2015-10-01 00:00:00

abstract：BACKGROUND:Angiotensin converting enzyme 2 (ACE2), a monocarboxylase that degrades angiotensin II to angiotensin 1-7, is also the functional receptor for severe acute respiratory syndrome (SARS) coronavirus (SARS-CoV) and is highly expressed in the lungs and heart. Patients with SARS also suffered from cardiac disease ...

journal_title：European journal of clinical investigation

authors： Oudit GY,Kassiri Z,Jiang C,Liu PP,Poutanen SM,Penninger JM,Butany J

更新日期：2009-07-01 00:00:00

abstract：BACKGROUND:The mammalian target of rapamycin (mTOR) has recently been implicated in leukaemic cell growth, tumour-associated angiogenesis and expression of vascular endothelial growth factor (VEGF). We examined whether mTOR plays a role as regulator of growth and VEGF-expression in acute myeloid leukaemia (AML). Three ...

journal_title：European journal of clinical investigation

authors： Böhm A,Aichberger KJ,Mayerhofer M,Herrmann H,Florian S,Krauth MT,Derdak S,Samorapoompichit P,Sonneck K,Vales A,Gleixner KV,Pickl WF,Sperr WR,Valent P

更新日期：2009-05-01 00:00:00

abstract：:It has been shown that the detection of tuberculostearic acid (TBSA) with gas chromatography-mass-spectrometry provides a highly specific, sensitive and rapid method for the diagnosis of various forms of tuberculosis. However, the need for complex and expensive equipment prevented the more widespread use of this metho...

journal_title：European journal of clinical investigation

authors： Herz A,Leichsenring M,Felten M,Oosthuizen OJ,Mayatepek E,Haas W,Bremer HJ

更新日期：1994-02-01 00:00:00

abstract：BACKGROUND:To prospectively evaluate the role of procalcitonin (PCT) in screening of patients with thyroid nodules for medullary thyroid carcinoma (MTC). MATERIALS AND METHODS:We measured PCT in 2705 patients with thyroid nodules referred to our centre between January 2011 and December 2017. Those with a positive PCT ...

journal_title：European journal of clinical investigation

authors： Giovanella L,Imperiali M,Piccardo A,Taborelli M,Verburg FA,Daurizio F,Trimboli P

更新日期：2018-06-01 00:00:00

abstract：BACKGROUND:Parental history of type 2 diabetes (T2D) is associated with cardiometabolic risk. We aimed to investigate the associations of parental history of T2D with cardiometabolic biomarkers and to subsequently investigate to what extent these putative associations were explained by modifiable factors. MATERIALS AN...

journal_title：European journal of clinical investigation

authors： Abbasi A,Corpeleijn E,van der Schouw YT,Stolk RP,Spijkerman A,van der A DL,Navis G,Bakker SJ,Beulens JW

更新日期：2012-09-01 00:00:00

abstract：:A significant rise in serum concentrations of aluminum was demonstrated in 23 patients prophylactically treated with the antacid magaldrate, whereas no increase in serum aluminium was observed in another 26 critically ill patients, in whom the use of antacids was avoided. In parallel, urinary excretion rates of alumin...

journal_title：European journal of clinical investigation

authors： Ittel TH,Gladziwa U,Mück W,Sieberth HG

更新日期：1991-02-01 00:00:00

abstract：:In the present study, the hypothesis that the affinity of LDL to arterial proteoglycans might discriminate myocardial infarction patients from controls were tested. The patients were 52 men who had sustained a myocardial infarction at an age of 50 years or less and the controls, selected from a random population sampl...

journal_title：European journal of clinical investigation

authors： Linden T,Bondjers G,Camejo G,Bergstrand R,Wilhelmsen L,Wiklund O

更新日期：1989-02-01 00:00:00

abstract：:The collagenolytic activities were assayed in fibroblast cultures established from ten keratoconus and six control corneal explants. The assays included those for both type I and type IV collagenase. The amount of free, directly assayable type I collagenase was highly increased in the media of keratoconus primary cell...

journal_title：European journal of clinical investigation

authors： Ihalainen A,Salo T,Forsius H,Peltonen L

更新日期：1986-02-01 00:00:00

abstract：:To assess the renal tubular damage in liver cirrhosis the fractional clearances of beta-2-microglobulin (B2m-fr.cl) and malate-dehydrogenase (MDH-fr.cl) were measured respectively in sixty-four and in forty-six out of seventy-nine patients with liver cirrhosis of different aetiology; furthermore the fractional excreti...

journal_title：European journal of clinical investigation

authors： Gatta A,Amodio P,Frigo A,Merkel C,Milani L,Zuin R,Ruol A

更新日期：1981-06-01 00:00:00

abstract：AIM:Observationally, low serum testosterone among men is associated with cardiovascular diseases and its risk factors, but it is unclear whether raising endogenous androgens would be protective. To clarify the role of androgens, the association of two different androgen biomarkers (serum testosterone and androstanediol...

journal_title：European journal of clinical investigation

authors： Schooling CM

更新日期：2013-12-01 00:00:00

abstract：OBJECTIVE:To evaluate comprehensively the effects of 12 prophylaxis interventions for secondary prophylaxis of variceal bleeding using multiple-treatments meta-analysis. METHODS:PubMed, EMBASE and the Cochrane Library were searched prior to November 2011. Randomized controlled trials (RCTs) comparing the interventions...

journal_title：European journal of clinical investigation

authors： Shi KQ,Liu WY,Pan ZZ,Ling XF,Chen SL,Chen YP,Fan YC,Zheng MH

更新日期：2013-08-01 00:00:00

abstract：:Levels of free anti-(xanthine oxidoreductase) (XOR) antibodies in the serum of normal healthy human subjects were determined, using both human and bovine enzyme as antigen, in an enzyme-linked immunosorbent assay (ELISA). Levels of IgM class anti-(human XOR) antibodies were found to be particularly high (mean values r...

journal_title：European journal of clinical investigation

authors： Benboubetra M,Gleeson A,Harris CP,Khan J,Arrar L,Brennand D,Reid J,Reckless JD,Harrison R

更新日期：1997-07-01 00:00:00

abstract：BACKGROUND:Analytical statistics revealed a variety of risk factors for hypertension, but the complex interplay between different factors remains to be determined by more powerful statistical techniques. METHODS:Analytical as well as new, explorative statistical methods such as natural segmentation (k-means) and predi...

journal_title：European journal of clinical investigation

authors： Lukas A,Kumbein F,Temml C,Mayer B,Oberbauer R

更新日期：2003-03-01 00:00:00

abstract：BACKGROUND:In the 13C-octanoate breath test, the shape of the 13CO2 excretion curve in the ascending portion reflects a pattern of gastric emptying (GE). Recent scintigraphic studies have revealed an overall delay in solid GE in fertile women compared with men. However, it remains unknown whether women have a different...

journal_title：European journal of clinical investigation

authors： Sanaka M,Yamamoto T,Anjiki H,Osaki Y,Kuyama Y

更新日期：2006-08-01 00:00:00

abstract：:To assess the degree of immune system activation associated with addiction or hepatotropic viruses infection, we examined 60 HIV-negative heroin addicts for the presence of hepatitis B virus (HBV) infection markers, hepatitis C virus antibodies (anti-HCV), various auto-antibodies, and serum levels of soluble interleuk...

journal_title：European journal of clinical investigation

authors： Dalekos GN,Manoussakis MN,Zervou E,Tsianos EV,Moutsopoulos HM

更新日期：1993-04-01 00:00:00

abstract：INTRODUCTION:Optimizing the approach to older adults with cancer is now a priority given the increasing frequency of new cancer diagnoses that are made in the older population. The comprehensive geriatric assessment (CGA) represents the gold-standard for (1) defining prognosis and ability to withstand cancer treatments...

journal_title：European journal of clinical investigation

authors： Fusco D,Ferrini A,Pasqualetti G,Giannotti C,Cesari M,Laudisio A,Ballestrero A,Scabini S,Odetti PR,Colloca GF,Monzani F,Nencioni A,Antonelli Incalzi R,Monacelli F,Oncogeriatrics Group of the Italian Society of Gerontology, Ger

更新日期：2021-01-01 00:00:00

abstract：BACKGROUND:Our aim in the present study was to determine whether endothelial NO synthase gene (ecNOS) polymorphisms are associated with myocardial infarction (MI). METHODS:Forty chromosomes from patients with MI were screened for polymorphisms of the ecNOS gene using polymerase chain reaction-single-strand conformatio...

journal_title：European journal of clinical investigation

authors： Poirier O,Mao C,Mallet C,Nicaud V,Herrmann SM,Evans A,Ruidavets JB,Arveiler D,Luc G,Tiret L,Soubrier F,Cambien F

更新日期：1999-04-01 00:00:00

abstract：BACKGROUND:Phospholipid transfer protein (PLTP) and cholesteryl ester transfer protein (CETP) remodel circulating lipoproteins and play a role in the antiatherogenic reverse cholesterol transport pathway. The present study determined whether abnormalities in the LDL subfraction pattern in type 2 diabetic patients were ...

journal_title：European journal of clinical investigation

authors： Tan KC,Shiu SW,Wong Y

更新日期：2003-04-01 00:00:00

abstract：BACKGROUND:Reduced aortic distensibility predicts cardiovascular mortality in patients with type 2 diabetes and impaired glucose tolerance. Cardiac autonomic neuropathy is common in subjects with diabetes. However, the relationship between the elastic properties of the aorta and autonomic neuropathy has not been studie...

journal_title：European journal of clinical investigation

authors： Tentolouris N,Liatis S,Moyssakis I,Tsapogas P,Psallas M,Diakoumopoulou E,Voteas V,Katsilambros N

更新日期：2003-12-01 00:00:00

abstract：BACKGROUND:Childhood obesity is associated with premature cardiovascular complications. However, little is known about the effect of a family-based behavioural intervention on the relationship between arterial function, blood pressure and biomarkers in pre-pubertal children with obesity. DESIGN:This was a single centr...

journal_title：European journal of clinical investigation

authors： Maggio ABR,Farpour-Lambert NJ,Aggoun Y,Galan K,Montecucco F,Mach F,Beghetti M

更新日期：2018-09-01 00:00:00

abstract：:Transfers or exchanges of cholesterol esters and triglycerides between lipoproteins are mediated by a specialized protein referred to as cholesteryl ester transfer protein (CETP), whereas those of phospholipids (PLs) are facilitated by both CETP and a specific phospholipid transfer protein (PLTP). In the present study...

journal_title：European journal of clinical investigation

authors： Elchebly M,Pulcini T,Porokhov B,Berthezene F,Ponsin G

更新日期：1996-03-01 00:00:00

abstract：:The effects of dazoxiben on finger-blood flow in response to cold challenge were studied in normal subjects and patients with Raynaud's phenomenon. In normal subjects concentrations of TXB2 and 6-oxo-PGF1 alpha were measured in blood taken from dorsal hand veins following cold challenge. In a parallel multicentre stud...

journal_title：European journal of clinical investigation

authors： Tindall H,Tooke JE,Menys VC,Martin MF,Davies JA

更新日期：1985-02-01 00:00:00

abstract：BACKGROUND:Glucocorticosteroids are effective in the treatment of allergic rhinitis, a disease characterized by a variety of symptoms, e.g. rhinorrhea and itching. The time course of symptomatic relief for allergic rhinitis by steroids has not been examined in detail to date, although the onset of steroid action is one...

journal_title：European journal of clinical investigation

authors： Tillmann HC,Stuck BA,Feuring M,Rossol-Haseroth K,Tran BM,Lösel R,Schmidt BM,Hörmann K,Wehling M,Schultz A

更新日期：2004-01-01 00:00:00

abstract：BACKGROUND:A high pulse pressure (PP) is associated with adverse cardiovascular (CV) outcomes; however, this relationship may be reversed in patients with heart failure with reduced ejection fraction (HFREF). METHODS:Patients from the WARCEF trial with left ventricular ejection fraction ≤35% were included. PP was divi...

journal_title：European journal of clinical investigation

authors： Shah N,Qian M,Di Tullio MR,Graham S,Mann DL,Sacco RL,Lip GYH,Labovitz AJ,Ponikowski P,Lok DJ,Anker SD,Teerlink JR,Thompson JLP,Homma S,Freudenberger RS,WARCEF Investigators.

更新日期：2019-02-23 00:00:00

abstract：:Hyperthyroidism is associated with an increase in both osteoblast and osteoclast activity. We have previously shown that, in vitro, osteoclasts do not respond directly to tri-iodothyronine to increase bone resorption but that the effect is mediated by another bone cell, probably the osteoblast. To investigate this iss...

journal_title：European journal of clinical investigation

authors： Allain TJ,Yen PM,Flanagan AM,McGregor AM

更新日期：1996-05-01 00:00:00

abstract：BACKGROUND:The aetiology of inguinal hernia includes changes in collagen turnover and metalloproteinase (MMP) expression, and direct hernia has been linked to increased MMP-2 expression. Since transforming growth factor beta1 (TGFbeta1) plays a role in tissue remodelling, this growth factor could directly affect metall...

journal_title：European journal of clinical investigation

authors： Pascual G,Corrales C,Gómez-Gil V,Buján J,Bellón JM

更新日期：2007-06-01 00:00:00

abstract：:The present study investigated how a cholinergic agonist modifies interdigestive motility and secretion of the upper gastrointestinal tract and how muscarinic and cholecystokinin receptor blockade interfere with this direct cholinergic stimulation. In eight healthy volunteers, gastrointestinal motor and secretory resp...

journal_title：European journal of clinical investigation

authors： Katschinski M,Steinicke C,Reinshagen M,Dahmen G,Beglinger C,Arnold R,Adler G

更新日期：1995-02-01 00:00:00