Radioimmunoassay of prostaglandins Falpha, E1 and E2 in human plasma.

abstract：BACKGROUND:Several clinical trials have suggested that a metabolic cocktail of glucose-insulin-potassium (GIK) decreases mortality rates in patients with acute myocardial infarction (AMI). It has also been reported that Fas-mediated apoptosis plays an important role in ischaemic/reperfusion injury in the rat model. Thi...

journal_title：European journal of clinical investigation

authors： Zhang L,Zhang L,Li YH,Zhang HY,Chen ML,Gao MM,Hu AH,Yang HS,Yang HS

更新日期：2005-03-01 00:00:00

abstract：BACKGROUND:Although the association between chronic Helicobacter pylori infection and type 2 diabetes has been suggested, findings have been inconsistent. This study evaluated the association between chronic H. pylori infection and glucose regulation. MATERIALS AND METHODS:We evaluated H. pylori infection status of pa...

journal_title：European journal of clinical investigation

authors： Hsieh MC,Wang SS,Hsieh YT,Kuo FC,Soon MS,Wu DC

更新日期：2013-09-01 00:00:00

abstract：:The pregnancies of two patients with mild intrahepatic cholestasis of pregnancy (RCP) were followed with detailed analyses of bile acids in urine. About twenty-five different bile acids were determined by GC/MS following separation according to mode of conjugation. The results were collated with the clinical course of...

journal_title：European journal of clinical investigation

authors： Thomassen PA

更新日期：1979-12-01 00:00:00

abstract：:Type V hyperlipoproteinaemia is a disorder of lipid transport characterized by the accumulation in serum of chylomicrons and very low density lipoproteins. The purpose of the study was the analysis of serum lipids and lipoproteins by ultracentrifugation in nine patients with primary type V hyperlipoproteinaemia before...

journal_title：European journal of clinical investigation

authors： Manzato E,Marin R,Gasparotto A,Baggio G,Martini S,Gabelli C,Crepaldi G

更新日期：1986-04-01 00:00:00

abstract：:The aim of this study was to assess the effect of intravenous dextran on bacterial translocation and intestinal vascular endothelial and epithelial barrier function after experimental partial hepatectomy. We determined systemic arterial pressure, enteric bacterial growth (proximal and distal small intestine and colon)...

journal_title：European journal of clinical investigation

authors： Wang XO,Sun ZW,Soltesz V,Deng XM,Andersson R

更新日期：1997-11-01 00:00:00

abstract：:To investigate the possible role of hepatitis C virus (HCV) in fulminant and subacute liver failure, we tested serum and liver of 13 patients undergoing orthotopic liver transplantation for the presence of HCV RNA. HCV RNA was detected in specimens from two out of eight patients negative for all viral markers with sus...

journal_title：European journal of clinical investigation

authors： Theilmann L,Solbach C,Toex U,Müller HM,Pfaff E,Otto G,Goeser T

更新日期：1992-08-01 00:00:00

abstract：BACKGROUND:Profilin-1 is a ubiquitous, actin-binding protein that plays an important role in the regulation of actin polymerization and cytoskeleton remodelling and contributes to vascular dysfunction. We conducted this study to investigate the association of serum profilin-1 levels with fatal and nonfatal CVE in a coh...

journal_title：European journal of clinical investigation

authors： Eroglu E,Unal HU,Guclu A,Kocyigit I,Karaman M,Saglam M,Gezer M,Tas A,Zararsiz G,Eyileten T,Aydin İ,Oguz Y,Gungor O,Yilmaz MI

更新日期：2017-12-01 00:00:00

abstract：BACKGROUND:Improvement of renal concentration capacity was long ago shown to occur after surgery for primary hyperparathyroidism (pHPT). Study of concentration capacity is of interest, as it was also shown to be a predictive factor for the risk of death in patients with pHPT, and it affected the risk of death independe...

journal_title：European journal of clinical investigation

authors： Hedbäck G,Abrahamsson K,Odén A

更新日期：2001-12-01 00:00:00

abstract：BACKGROUND:Antiphospholipid syndrome (APS) is a systemic autoimmune vascular disease characterized by recurrent thrombotic episodes and/or obstetric complications. Management of this disease has been restricted mainly to anticoagulation; however, in recent years, significant advancement has been made in elucidating the...

journal_title：European journal of clinical investigation

authors： Mehdi AA,Uthman I,Khamashta M

更新日期：2010-05-01 00:00:00

abstract：BACKGROUND:Stiff Person Syndrome (SPS) is a relatively rare but often overlooked autoimmune neurological disorder that targets antigens within the brain's inhibitory pathways resulting in incapacitating stiffness and spasms that impact on the patients' quality of life. Although a number of immunomodulating therapies si...

journal_title：European journal of clinical investigation

authors： Alexopoulos H,Dalakas MC

更新日期：2010-11-01 00:00:00

abstract：:Platelet aggregation induced by collagen, ADP and epinephrine, was monitored in 150 type-II patients (115 type IIA and 35 type IIB) and compared with a reference group of normolipidaemic controls; in addition, malondialydehyde formation and thromboxane B2 were examined in a subsample of the type-IIA patients. Threshol...

journal_title：European journal of clinical investigation

authors： Tremoli E,Maderna P,Colli S,Morazzoni G,Sirtori M,Sirtori CR

更新日期：1984-10-01 00:00:00

abstract：OBJECTIVE:To evaluate comprehensively the effects of 12 prophylaxis interventions for secondary prophylaxis of variceal bleeding using multiple-treatments meta-analysis. METHODS:PubMed, EMBASE and the Cochrane Library were searched prior to November 2011. Randomized controlled trials (RCTs) comparing the interventions...

journal_title：European journal of clinical investigation

authors： Shi KQ,Liu WY,Pan ZZ,Ling XF,Chen SL,Chen YP,Fan YC,Zheng MH

更新日期：2013-08-01 00:00:00

abstract：:Inflammation is a well-coordinated process in response to tissue injury or infection aimed at restoration of tissue homoeostasis. Platelets and neutrophils are typically viewed important in the context of haemostasis and bacterial killing, respectively. However, as these cells are equipped with readily available armou...

journal_title：European journal of clinical investigation

authors： Soehnlein O

更新日期：2018-02-01 00:00:00

abstract：BACKGROUND:Adiponectin is an insulin-sensitizing, antiatherogenic and anti-inflammatory adipocytokine that circulates in three isoforms: a trimer [low-molecular weight (LMW)], a hexamer (trimer-dimer) of medium molecular weight (MMW) and a multimeric high molecular weight (HMW) isoform. Evidence is accumulating that HM...

journal_title：European journal of clinical investigation

authors： Kaser S,Tatarczyk T,Stadlmayr A,Ciardi C,Ress C,Tschoner A,Sandhofer A,Paulweber B,Ebenbichler CF,Patsch JR

更新日期：2008-11-01 00:00:00

abstract：BACKGROUND:There is ongoing controversy whether angiotensin-converting enzyme inhibitors (ACE-I) contribute to anaemia by causing hyporesponsiveness to erythropoiesis-stimulating agents (ESA). However, it is unknown whether or not plasma levels or area under the curve (AUC) of ACE-I are associated with responsiveness t...

journal_title：European journal of clinical investigation

authors： Winnicki W,Prehslauer A,Kletzmayr J,Herkner H,Sunder-Plassmann G,Brunner M,Hörl WH,Sengoelge G

更新日期：2012-10-01 00:00:00

abstract：BACKGROUND:Mucosal-associated invariant T (MAIT) cells play an important role in innate host defence. MAIT cells appear to undergo exhaustion and are functionally weakened in chronic viral infections. However, their role in chronic hepatitis C virus (HCV) infection remains unclear. MATERIALS AND METHODS:We investigate...

journal_title：European journal of clinical investigation

authors： Barathan M,Mohamed R,Vadivelu J,Chang LY,Saeidi A,Yong YK,Ravishankar Ram M,Gopal K,Velu V,Larsson M,Shankar EM

更新日期：2016-02-01 00:00:00

abstract：BACKGROUND:Cold ischaemic (CI) injury is associated with reduced renal graft function and survival. However, there is little evidence on the benefits of reducing CI injury within a 24 h period in donation after cardiac death (DCD) kidney transplantation. METHODS:Porcine kidneys subjected to 10-min warm ischaemia were ...

journal_title：European journal of clinical investigation

authors： Hosgood SA,Bagul A,Nicholson ML

更新日期：2011-03-01 00:00:00

abstract：:Circulating immune complexes (ICs) were isolated by affinity chromatography and sucrose density gradient fractionation during acute and chronic hepatitis C virus (HCV) infection. Immunochemical and biomolecular studies showed that they basically consist of the virus component, IgG with specific anti-HCV activity and I...

journal_title：European journal of clinical investigation

authors： Sansonno D,Iacobelli AR,Cornacchiulo V,Lauletta G,Distasi MA,Gatti P,Dammacco F

更新日期：1996-06-01 00:00:00

abstract：:The metabolic responses to 4-h infusions of adrenaline (3 micrograms kg-1 h-1) and cortisol (10 mg m-2 h-1 for 2 h followed by 5 mg m-2 h-1 for 2 h), separately and in combination, have been studied in six healthy subjects with concurrent somatostatin infusion (250 micrograms h-1). A combined infusion of adrenaline, c...

journal_title：European journal of clinical investigation

authors： Pernet A,Johnston DG,Hammond V,Orskov H,Alberti KG

更新日期：1986-08-01 00:00:00

abstract：:Factors affecting erythrocyte K+ content and plasma electrolytes during light exercise were examined in 8 normal subjects and 27 patients with chronic obstructive lung disease. The patients were classified into bronchitis, emphysema and intermediate groups. Arterial blood was obtained during rest, after 2, 5, and 7 mi...

journal_title：European journal of clinical investigation

authors： Kawakami Y,Kishi F,Uchiyama K,Irie T,Murao M

更新日期：1975-09-12 00:00:00

abstract：BACKGROUND:Plasmacytoid dendritic cells (pDCs) are multifunctional bone-marrow-derived immune cells that are key players in bridging the innate and adaptive immune systems. Activation of pDCs through toll-like receptor agonists has proven to be an effective treatment for some neoplastic disorders. MATERIALS AND METHOD...

journal_title：European journal of clinical investigation

authors： Lombardi VC,Khaiboullina SF,Rizvanov AA

更新日期：2015-01-01 00:00:00

abstract：:Transfers or exchanges of cholesterol esters and triglycerides between lipoproteins are mediated by a specialized protein referred to as cholesteryl ester transfer protein (CETP), whereas those of phospholipids (PLs) are facilitated by both CETP and a specific phospholipid transfer protein (PLTP). In the present study...

journal_title：European journal of clinical investigation

authors： Elchebly M,Pulcini T,Porokhov B,Berthezene F,Ponsin G

更新日期：1996-03-01 00:00:00

abstract：:Increased plasma levels of soluble adhesion molecules are associated with an increased risk of atherothrombosis. The pathophysiological mechanisms responsible for these associations are not known. The aim of the present study was to investigate the association of soluble intercellular adhesion molecule-1 (sICAM-1) con...

journal_title：European journal of clinical investigation

authors： Becker A,van Hinsbergh VW,Jager A,Kostense PJ,Dekker JM,Nijpels G,Heine RJ,Bouter LM,Stehouwer CD

更新日期：2002-01-01 00:00:00

abstract：:The permeability of the gastrointestinal tract was investigated by means of polyethylene glycol (PEG), given orally. The PEG solutions contained oligomers with molecular weights from 414 to 1206. The urinary recovery of ingested PEG was determined by high performance liquid chromatography (HPLC). Considerable inter- a...

journal_title：European journal of clinical investigation

authors： Philipsen EK,Batsberg W,Christensen AB

更新日期：1988-04-01 00:00:00

abstract：BACKGROUND:Preliminary data suggest that serum uric acid (SUA) could be involved in the prognosis of chronic heart failure (HF). The aim of our study was to test the relationship between SUA and left ventricular ejection fraction (EF%) in a cohort of elderly hypertensive outpatients with chronic HF. DESIGN:We consecut...

journal_title：European journal of clinical investigation

authors： Borghi C,Cosentino ER,Rinaldi ER,Cicero AF

更新日期：2014-06-01 00:00:00

abstract：:Pancreatic polypeptide was infused intravenously in healthy fasting subjects at 1 pmol kg-1 (n = 7) and 4 pmol kg-1 min-1 (n = 10) producing plasma PP concentrations of 223 +/- 37 pmol/l (mean +/- SEM) and 891 +/- 64 pmol/l respectively. These levels are similar to and four-fold higher than those seen after a normal m...

journal_title：European journal of clinical investigation

authors： Adrian TE,Greenberg GR,Barnes AJ,Christofides ND,Alberti KG,Bloom SR

更新日期：1980-06-01 00:00:00

abstract：:Administration of the murine IgG2a CD3 monoclonal antibody OKT3 exerts a transient nephrotoxic effect. Increased levels of group II secretory phospholipase A2 (sPLA2-II) might account for this nephrotoxicity as sPLA2-II induces the biosynthesis of prostaglandins, vasoactive lipid mediators that influence glomerular ha...

journal_title：European journal of clinical investigation

authors： Wever PC,Roest RW,Wolbink-Kamp AM,Wolbink GJ,Weening JJ,Hack CE,ten Berge JM

更新日期：1996-10-01 00:00:00

abstract：BACKGROUND:Complement fragment C5a and neutrophils have been implicated in the pathogenesis of renal disease and C5a has also been shown to delay apoptosis of human neutrophils via a transcription-independent pathway. However, transcription-dependent pathways have not been well described. The present study examined whe...

journal_title：European journal of clinical investigation

authors： Perianayagam MC,Madias NE,Pereira BJ,Jaber BL

更新日期：2006-05-01 00:00:00

abstract：BACKGROUND:Carotid ultrasound is a noninvasive tool for risk assessment of coronary artery disease (CAD). There is no consensus on which carotid ultrasound parameter constitutes the best measurement of atherosclerosis. We investigated which model of carotid ultrasound parameters and clinical risk factors (CRF) has the ...

journal_title：European journal of clinical investigation

authors： Wu N,Chen X,Li M,Qu X,Li Y,Xie W,Wu L,Xiang Y,Li Y,Zhong L

更新日期：2018-08-01 00:00:00

abstract：BACKGROUND:Plasma brain natriuretic peptide (BNP) is elevated in asymptomatic patients with various cardiac abnormalities. We tested the hypothesis that measuring BNP is useful for detecting asymptomatic patients with cardiac abnormalities who are not identified by conventional health check-up programmes. MATERIALS AN...

journal_title：European journal of clinical investigation

authors： Takase H,Toriyama T,Sugiura T,Takahashi A,Sugiyama M,Ohashi M,Ueda R,Dohi Y

更新日期：2007-04-01 00:00:00