Abstract:
PURPOSE:The histamine-2 (H(2)) blocker cimetidine may alter androgen, zinc, and prolactin levels, which could alter prostate cancer risk. Increased risk for men filling more than 20 cimetidine prescriptions was reported previously. We examined the association between cimetidine use and prostate cancer risk in a cohort in western Washington State. METHODS:Participants were 33,506 men, 50 to 76 years old, enrolled in the VITamins And Lifestyle cohort (VITAL). H(2)-blocker use during the prior 10 years was self-reported through baseline questionnaire between October 2000 and December 2002. Men were followed up for subsequent prostate cancer by linkage to the Surveillance, Epidemiology and End Results cancer registry. We identified 548 incident invasive prostate cancer cases diagnosed from baseline to December 31, 2003. RESULTS:Overall, no association between ever use of cimetidine or years of cimetidine use and prostate cancer risk was observed. However, daily cimetidine use for 10 years was associated with increased risk (relative risk, 2.35; 95% confidence interval, 1.05-5.26) compared with nonuse of any H(2) blockers. Use of other H(2) blockers was not associated with prostate cancer. CONCLUSIONS:Additional studies are needed to determine whether long-term daily cimetidine use is associated with increased prostate cancer risk in other populations, and if so, the reason for this association.
journal_name
Ann Epidemioljournal_title
Annals of epidemiologyauthors
Velicer CM,Dublin S,White Edoi
10.1016/j.annepidem.2006.03.003subject
Has Abstractpub_date
2006-12-01 00:00:00pages
895-900issue
12eissn
1047-2797issn
1873-2585pii
S1047-2797(06)00072-Xjournal_volume
16pub_type
杂志文章abstract::The association between premature menopause and low back pain was examined among 5325 women surveyed in the second National Health and Nutrition Examination survey. Nearly 49% of the women were postmenopausal. In a multiple logistic regression model that included age, postmenopausal women were approximately twice as l...
journal_title:Annals of epidemiology
pub_type: 杂志文章
doi:10.1016/1047-2797(94)90077-9
更新日期:1994-09-01 00:00:00
abstract:PURPOSE:Life expectancy is used to measure population health, but large differences in mortality can be masked even when there is no life expectancy gap. We demonstrate how Arriaga's decomposition method can be used to assess inequality in mortality between populations with near equal life expectancy. METHODS:We calcu...
journal_title:Annals of epidemiology
pub_type: 杂志文章
doi:10.1016/j.annepidem.2014.05.006
更新日期:2014-08-01 00:00:00
abstract:PURPOSE:To examine the association of depressive symptoms with coronary heart disease (CHD) end points by race and income. METHODS:Study participants were blacks and whites (n = 24,443) without CHD at baseline from the national Reasons for Geographical and Racial Differences in Stroke cohort. Outcomes included acute C...
journal_title:Annals of epidemiology
pub_type: 杂志文章
doi:10.1016/j.annepidem.2015.03.014
更新日期:2015-06-01 00:00:00
abstract:PURPOSE:In 1991, California implemented a law that mandated a background check for all firearm purchases with limited exceptions (comprehensive background check or CBC policy) and prohibited firearm purchase and possession for persons convicted within the past 10 years of certain violent crimes classified as misdemeano...
journal_title:Annals of epidemiology
pub_type: 杂志文章
doi:10.1016/j.annepidem.2018.10.001
更新日期:2019-02-01 00:00:00
abstract:PURPOSE:This cross-sectional study sought to identify diabetes accurately in a study population of 3681 women age 75 and older and to determine the association of diabetes with cognitive performance. METHODS:A previously validated test, the Telephone Interview of Cognitive Screening-Modified (TICSm) was given to asses...
journal_title:Annals of epidemiology
pub_type: 杂志文章
doi:10.1016/S1047-2797(03)00059-0
更新日期:2003-10-01 00:00:00
abstract:PURPOSE:In longitudinal studies, the onset of the index condition (e.g. exposure) does not always coincide with the start of a study's observation period, leading to the possibility of bias in estimation that derives from studying prevalent exposure rather than new exposure. We investigate the possible role of this bia...
journal_title:Annals of epidemiology
pub_type: 杂志文章
doi:10.1016/j.annepidem.2014.07.006
更新日期:2014-10-01 00:00:00
abstract:PURPOSE:We examined whether differences in findings of studies examining mild cognitive impairment (MCI) were associated with recruitment methods by comparing sample characteristics in two contemporaneous Australian studies, using population-based and convenience sampling. METHOD:The Sydney Memory and Aging Study invi...
journal_title:Annals of epidemiology
pub_type: 杂志文章
doi:10.1016/j.annepidem.2013.10.005
更新日期:2014-01-01 00:00:00
abstract:BACKGROUND:A common epidemiologic objective is to evaluate the contribution of residential context to individual-level disparities by race or socioeconomic position. PURPOSE:We reviewed analytic strategies to account for the total (observed and unobserved factors) contribution of environmental context to health inequa...
journal_title:Annals of epidemiology
pub_type: 杂志文章,评审
doi:10.1016/j.annepidem.2012.06.105
更新日期:2012-10-01 00:00:00
abstract:PURPOSE:To examine the clustering and patterns of obesity-related behaviors in children and their mothers and the concordance between mother and child pairs. METHODS:Primary school-aged children and their mothers in Victoria, Australia, participated (data from 549 mothers, 352 children, and 304 mother/child pairs). Ex...
journal_title:Annals of epidemiology
pub_type: 杂志文章
doi:10.1016/j.annepidem.2010.11.001
更新日期:2011-02-01 00:00:00
abstract::National and international policy-making organizations advocate nonpharmacologic therapies to reduce blood pressure (BP). However, data to support such recommendations in older persons are virtually nonexistent. The Trials of Nonpharmacologic Intervention in the Elderly (TONE) is a randomized, controlled trial that wi...
journal_title:Annals of epidemiology
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:10.1016/1047-2797(94)00056-y
更新日期:1995-03-01 00:00:00
abstract:PURPOSE:Serum concentrations of the adrenal androgen dehydroepiandrosterone (DHEA) and its sulfate ester (DHEAS), both of which decline with age more markedly than other sex hormone levels, have been alternately credited and discredited as "protective" correlates of heart disease. Baseline data from the Massachusetts M...
journal_title:Annals of epidemiology
pub_type: 杂志文章
doi:10.1016/s1047-2797(97)00199-3
更新日期:1998-05-01 00:00:00
abstract:PURPOSE:Propose a five-step multigating, multimodal procedure for research case definition and identification of attention-deficit/hyperactivity disorder (AD/HD) in population-based epidemiologic studies. METHODS:Subjects included a birth cohort of all children born between 1976 and 1982 who remained in Rochester afte...
journal_title:Annals of epidemiology
pub_type: 杂志文章
doi:10.1016/j.annepidem.2004.12.004
更新日期:2005-07-01 00:00:00
abstract:PURPOSE:The Multiple Risk Factor Intervention Trial (MRFIT), a randomized clinical trial for the primary prevention of coronary heart disease, enrolled 12,866 men (including 8194 cigarette smokers) aged 35-57 years at 22 clinical centers across the United States. Participants were randomized either to special intervent...
journal_title:Annals of epidemiology
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:10.1016/s1047-2797(96)00123-8
更新日期:1997-02-01 00:00:00
abstract::Information obtained during the past decade suggests that the onset of myocardial infarction and sudden cardiac death is frequently triggered by daily activities. The importance of physical or mental stress in triggering coronary thrombosis is supported by finding that (1) the frequencies of the onset of myocardial in...
journal_title:Annals of epidemiology
pub_type: 杂志文章
doi:10.1016/1047-2797(92)90088-8
更新日期:1992-07-01 00:00:00
abstract:PURPOSE:Depression is a risk factor for incident coronary heart disease (CHD), and predicts poor prognosis for patients post-myocardial infarction (MI). Few population-based, prospective studies have tested a gradient risk for depressive symptoms on CHD incidence. METHODS:The sample (n=1302) was derived from the Nova ...
journal_title:Annals of epidemiology
pub_type: 杂志文章
doi:10.1016/j.annepidem.2004.08.006
更新日期:2005-04-01 00:00:00
abstract:PURPOSE:In several biomedical studies, one or more exposures of interest may be subject to nonrandom missingness because of the failure of the measurement assay at levels below its limit of detection. This issue is commonly encountered in studies of the metabolome using tandem mass spectrometry-based technologies. Owin...
journal_title:Annals of epidemiology
pub_type: 杂志文章
doi:10.1016/j.annepidem.2019.07.014
更新日期:2019-10-01 00:00:00
abstract:PURPOSE:An association has been consistently found between diabetes mellitus and decreased lung function. We evaluated to what extent low-grade inflammation (as measured by the level of high-sensitivity C-reactive protein [hs-CRP]) could explain this relationship. METHODS:A sample of 1878 middle-aged adults from the c...
journal_title:Annals of epidemiology
pub_type: 杂志文章
doi:10.1016/j.annepidem.2017.11.004
更新日期:2018-01-01 00:00:00
abstract:PURPOSE:To evaluate the association between active and passive smoking and frequency of colds in women. METHODS:Data on cigarette smoking and frequency and duration of colds were analyzed in the Women's Health Study (WHS), a randomized, double-blind, placebo-controlled trial of low-dose aspirin and vitamin E in the pr...
journal_title:Annals of epidemiology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/s1047-2797(00)00214-3
更新日期:2001-05-01 00:00:00
abstract:PURPOSE:We examined the role of smoking in the two dimensions behind the time trends in adult mortality in European countries, that is, rectangularization of the survival curve (mortality compression) and longevity extension (increase in the age-at-death). METHODS:Using data on national sex-specific populations aged 5...
journal_title:Annals of epidemiology
pub_type: 杂志文章
doi:10.1016/j.annepidem.2015.01.007
更新日期:2015-04-01 00:00:00
abstract:PURPOSE:Whether or which blood heavy metal levels (BHMLs) influence elevating intraocular pressure (IOP) are unknown. We examined the relationship among blood lead, mercury, and cadmium levels, blood pressure (BP), and IOP and assessed whether BP mediates these BHMLs-IOP associations. METHODS:We analyzed data on 8371 ...
journal_title:Annals of epidemiology
pub_type: 杂志文章
doi:10.1016/j.annepidem.2016.07.002
更新日期:2016-08-01 00:00:00
abstract:PURPOSE:Studies of middle-aged and particularly older-aged adults found that those with higher scores on tests of IQ (cognitive function) had lower rates of later mortality. Interpretation of such findings potentially is hampered by the problem of reverse causality: such somatic diseases as diabetes or hypertension, co...
journal_title:Annals of epidemiology
pub_type: 杂志文章,评审
doi:10.1016/j.annepidem.2006.07.010
更新日期:2007-04-01 00:00:00
abstract:PURPOSE:Incidence studies of occupational factors and cancer in the United States are problematic because the use of population-based registries to identify cases requires development of historical data on subjects' residences and often severely restricts the time period of follow up. This article describes procedures ...
journal_title:Annals of epidemiology
pub_type: 杂志文章
doi:10.1016/j.annepidem.2005.06.055
更新日期:2006-03-01 00:00:00
abstract:PURPOSE:A literature review was performed of the three principal subpopulations most commonly associated with human T-cell lymphotropic virus type II (HTLV-II) with the view of identifying the prevalence and transmission routes of HTLV-II. These included blood donors (BDs), intravenous drug users (IVDUs), and Amerindia...
journal_title:Annals of epidemiology
pub_type: 杂志文章,评审
doi:10.1016/s1047-2797(01)00231-9
更新日期:2002-01-01 00:00:00
abstract:PURPOSE:To examine whether maternal fever during pregnancy is associated with reduced head circumference and risk of microcephaly at birth. METHODS:A prospective study of 86,980 live-born singletons within the Danish National Birth Cohort was carried out. Self-reported maternal fever exposure was ascertained in two in...
journal_title:Annals of epidemiology
pub_type: 杂志文章
doi:10.1016/j.annepidem.2017.11.011
更新日期:2018-02-01 00:00:00
abstract:PURPOSE:We aim to shed light on progress in cancer medicine through studying time trends in age-specific rates of cancer incidence and mortality over the last quarter century. METHODS:We analyzed age-specific incidence and mortality rates of all cancer sites combined using the high-quality population-based databases o...
journal_title:Annals of epidemiology
pub_type: 杂志文章
doi:10.1016/j.annepidem.2020.04.007
更新日期:2020-08-01 00:00:00
abstract:PURPOSE:To identify, map, and synthesize the individual-level key associations and modes of exposure for hepatitis C virus (HCV) infection in the Middle East and North Africa (MENA), the most affected region by HCV. METHODS:Source of data was the MENA HCV Epidemiology Synthesis Project database, populated through syst...
journal_title:Annals of epidemiology
pub_type: 杂志文章
doi:10.1016/j.annepidem.2018.03.007
更新日期:2018-07-01 00:00:00
abstract::In Japan, stroke now ranks third among all causes of death following cancer and heart disease. Stroke was the leading cause of death for 3 decades after 1951. Stroke mortality tended to increase until about 1970, but it decreased and yielded first place to cancer in 1981. Heart disease deaths outnumbered stroke deaths...
journal_title:Annals of epidemiology
pub_type: 杂志文章
doi:10.1016/1047-2797(93)90109-h
更新日期:1993-09-01 00:00:00
abstract:PURPOSE:To examine community differences in cardiovascular disease (CVD) risk factors among black and white young adults by combining data from two large epidemiologic studies. METHODS:Data are from participants aged 20-31 years in the Coronary Artery Risk Development In Young Adults (CARDIA) study (1987-1988; N = 412...
journal_title:Annals of epidemiology
pub_type: 杂志文章
doi:10.1016/s1047-2797(97)00127-0
更新日期:1998-01-01 00:00:00
abstract:PURPOSE:The case-crossover design was originally intended to study brief exposures with immediate and transient effects, and acute outcomes with abrupt onsets. We investigated whether case-crossover methods can be used to study prolonged exposures and insidious outcomes. METHODS:We conducted a case-crossover study of ...
journal_title:Annals of epidemiology
pub_type: 杂志文章
doi:10.1016/j.annepidem.2003.09.012
更新日期:2004-04-01 00:00:00
abstract:PURPOSE:Examine the complex relationships among metabolic syndrome components in black and white individuals by growth periods. METHODS:Path analyses of metabolic syndrome components were performed on 8203 black and white healthy subjects (64.3% white and 47.9% male) comprising children (4-11 years), adolescents (12-1...
journal_title:Annals of epidemiology
pub_type: 杂志文章
doi:10.1016/j.annepidem.2007.07.090
更新日期:2008-02-01 00:00:00