Abstract：
PURPOSE:The case-crossover design was originally intended to study brief exposures with immediate and transient effects, and acute outcomes with abrupt onsets. We investigated whether case-crossover methods can be used to study prolonged exposures and insidious outcomes. METHODS:We conducted a case-crossover study of 8220 patients aged > or = 65 years enrolled in several health benefits programs in New Jersey during the period between 1991 and 1995. All had episodes of central nervous system (CNS) adverse events (e.g., delirium). Drug exposures were assessed during case time periods and control time periods lasting 1, 2, 3, or 4 months. Exposures included 3 active regimens with established deleterious CNS effects (corticosteroids, digoxin, and opiates) and 2 inactive regimens without such effects (multivitamins and statins). RESULTS:In conditional logistic regression models, significantly elevated risks were observed for all three active drugs, regardless of which time windows were used. The magnitude of these risks generally increased with longer time windows. No significantly increased risks were observed for the 2 inactive drugs, regardless of the window duration. CONCLUSIONS:These results suggest that with lengthened exposure assessment windows, case-crossover methods may be useful for studying exposures with prolonged effects and outcomes with insidious onsets.
journal_name
Ann Epidemioljournal_title
Annals of epidemiologyauthors
Wang PS,Schneeweiss S,Glynn RJ,Mogun H,Avorn Jdoi
10.1016/j.annepidem.2003.09.012keywords:
subject
Has Abstractpub_date
2004-04-01 00:00:00pages
296-303issue
4eissn
1047-2797issn
1873-2585pii
S1047279703003326journal_volume
14pub_type
杂志文章abstract：PURPOSE:The mucosa of the small intestine encompasses about 90% of the luminal surface area of the digestive system, but only 2% of the total annual gastrointestinal cancer incidence in the United States. METHODS:The remarkable contrast in age-standardized cancer incidence between the small and large intestine has bee...
journal_title：Annals of epidemiology
pub_type： 杂志文章,评审
doi：10.1016/j.annepidem.2008.10.004
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abstract：PURPOSE:Maternal asthma increases adverse neonatal respiratory outcomes, and pollution may further increase risk. Air quality in relation to neonatal respiratory health has not been studied. METHODS:Transient tachypnea of the newborn (TTN), asphyxia, and respiratory distress syndrome (RDS) were identified using medica...
journal_title：Annals of epidemiology
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abstract：BACKGROUND:We sought to determine if the rate of increase in body mass index (BMI) differs between first generation immigrant children (child and both parents born outside Canada); second generation immigrant children (child born in Canada with at least one parent born outside Canada); and native-born children (child a...
journal_title：Annals of epidemiology
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doi：10.1016/j.annepidem.2011.01.002
更新日期：2011-04-01 00:00:00
abstract：PURPOSE:To investigate the association of nativity status, country of origin, and race with all-cause mortality in Hispanic adults relative to non-Hispanic adults in the United States, we used 565,352 records of participants 25 years and older from years 1990 to 2000 of the National Health Interview Survey linked to th...
journal_title：Annals of epidemiology
pub_type： 杂志文章
doi：10.1016/j.annepidem.2008.12.003
更新日期：2009-05-01 00:00:00
abstract：PURPOSE:The aim of the study was to assess the relationship between age of arrival of male pediatric immigrant populations in Israel and their risk for subsequent high-weight morbidity at adolescence. METHODS:The study analyzed a pooled cross section of 89,744 foreign-born male Jewish study participants, who were born...
journal_title：Annals of epidemiology
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更新日期：2014-06-01 00:00:00
abstract：PURPOSE:Existing studies on laxatives, used by roughly 40% of the U.S. population experiencing constipation and colorectal cancer (CRC) have yielded inconsistent results, which may be due to a failure to account for differential risks by major laxative types: bulk (fiber-based), and nonbulk (or nonfiber-based). METHOD...
journal_title：Annals of epidemiology
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doi：10.1016/j.annepidem.2018.06.011
更新日期：2018-10-01 00:00:00
abstract：PURPOSE:A review of recent threats and challenges to epidemiology suggests that some represent an opportunity to advance the discipline while others are a major threat to conducting epidemiologic work. METHODS:Two issues are identified which should advance the publication and conduct of epidemiologic research. Three a...
journal_title：Annals of epidemiology
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doi：10.1016/s1047-2797(97)00206-8
更新日期：1998-02-01 00:00:00
abstract：PURPOSE:To evaluate the association between physical activity (PA) across the menstrual cycle and reproductive function. METHODS:The BioCycle Study (2005-2007) followed 259 healthy premenopausal women not using hormonal contraceptives for up to two menstrual cycles (N = 509 cycles). Serum leptin, estradiol, progestero...
journal_title：Annals of epidemiology
pub_type： 杂志文章
doi：10.1016/j.annepidem.2013.11.002
更新日期：2014-02-01 00:00:00
abstract：PURPOSE:The metabolic syndrome (MS) is conceived as a cluster of disorders that increase risk for coronary heart disease and type 2 diabetes. Studies examining its structure primarily have used an exploratory factor analytic technique, but yielded discrepant results. There also is a lack of research that investigates w...
journal_title：Annals of epidemiology
pub_type： 杂志文章
doi：10.1016/j.annepidem.2005.06.049
更新日期：2006-02-01 00:00:00
abstract：:The validity of a 77-item food-frequency questionnaire (FFQ) developed for a multicenter case-control study on diet and cancer in Italy was assessed. Trained interviewers administered the same FFQ to 452 volunteers from three Italian provinces (Pordenone, Genoa, and Forli) completed in two different seasons, at an int...
journal_title：Annals of epidemiology
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更新日期：1996-03-01 00:00:00
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journal_title：Annals of epidemiology
pub_type： 杂志文章
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更新日期：2018-08-01 00:00:00
abstract：PURPOSE:The purpose of this study is to map type 2 diabetes susceptibility genes in West African ancestral populations of African-Americans, through an international collaboration between West African and US investigators. DESIGN AND METHODS:Affected sib-pairs (ASP) along with unaffected spouse controls are being enro...
journal_title：Annals of epidemiology
pub_type： 杂志文章
doi：10.1016/s1047-2797(00)00180-0
更新日期：2001-01-01 00:00:00
abstract：PURPOSE:Poor and disparate reproductive health outcomes in the United States may be related to inadequate and differential receipt of women's health care. We investigated trends in and determinants of adult U.S. women's health service use, 2006-2010. METHODS:We analyzed population data from 7897 women aged 25-44 years...
journal_title：Annals of epidemiology
pub_type： 杂志文章
doi：10.1016/j.annepidem.2013.10.018
更新日期：2014-02-01 00:00:00
abstract：PURPOSE:To investigate the possible association between ibuprofen use and dermatologic superinfections among children with recent varicella infection. METHODS:A retrospective cohort study of children in Harvard Pilgrim Health Care, a health maintenance organization in New England, was conducted. Outcomes and exposures...
journal_title：Annals of epidemiology
pub_type： 杂志文章
doi：10.1016/s1047-2797(97)00040-9
更新日期：1997-10-01 00:00:00
abstract：PURPOSE:Heterogeneous findings exist on antiretroviral therapy (ART) use in pregnancy and preterm delivery (PTD) or infants born small-for-gestational age (SGA). Whether reported differences may be explained by methods used to ascertain gestational age (GA) has not been explored. METHODS:We enrolled consecutive pregna...
journal_title：Annals of epidemiology
pub_type： 杂志文章
doi：10.1016/j.annepidem.2018.08.011
更新日期：2018-12-01 00:00:00
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journal_title：Annals of epidemiology
pub_type： 杂志文章
doi：10.1016/j.annepidem.2011.06.003
更新日期：2011-10-01 00:00:00
abstract：:PURPOSE: Although prison inmates are reported to exhibit substantially elevated rates of HIV infection, little is known about HIV treatment patterns, particularly pharmacotherapy, in correctional institutions. The purpose of the present study, therefore, was to describe antiretroviral prescribing patterns in one of th...
journal_title：Annals of epidemiology
pub_type： 杂志文章
doi：10.1016/s1047-2797(00)00128-9
更新日期：2000-10-01 00:00:00
abstract：PURPOSE:We sought to examine the importance of childhood circumstances, adult socioeconomic status, and material circumstances to physical and mental functioning among middle-aged women and men. METHODS:The data were collected among the employees of the City of Helsinki by mailed questionnaires from 2000 to 2002 (7148...
journal_title：Annals of epidemiology
pub_type： 杂志文章
doi：10.1016/j.annepidem.2006.11.003
更新日期：2007-06-01 00:00:00
abstract：PURPOSE:Although prospective data are limited, recent cross-sectional studies support obesity as a cause of asthma. They also suggest that the association is present only among women. Our analysis examines possible sex-race differences in the relationship between obesity and asthma. METHODS:We examined data from the 2...
journal_title：Annals of epidemiology
pub_type： 杂志文章
doi：10.1016/s1047-2797(03)00054-1
更新日期：2003-11-01 00:00:00
abstract：PURPOSE:Alcohol consumption has been implicated in the pathogenesis of cataract in some, but not all analytic studies. To date, no prospective analysis of the relationship between alcohol consumption and cataract has been conducted in women. METHODS:We examined the association between alcohol consumption and cataract ...
journal_title：Annals of epidemiology
pub_type： 杂志文章
doi：10.1016/s1047-2797(00)00054-5
更新日期：2000-08-01 00:00:00
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journal_title：Annals of epidemiology
pub_type： 杂志文章
doi：10.1016/j.annepidem.2009.11.013
更新日期：2010-03-01 00:00:00
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journal_title：Annals of epidemiology
pub_type： 杂志文章
doi：10.1016/j.annepidem.2011.10.011
更新日期：2012-02-01 00:00:00
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journal_title：Annals of epidemiology
pub_type： 杂志文章
doi：10.1016/j.annepidem.2014.10.008
更新日期：2015-01-01 00:00:00
abstract：PURPOSE:To examine mental health indicators, in aggregate and stratified by sex, among a population-based sample of U.S. military veterans. METHODS:Data are from veteran who completed the Veterans Health Module (VHM) of the 2011 and 2012 Behavioral Risk Factor Surveillance System (n = 10,406). VHM items included lifet...
journal_title：Annals of epidemiology
pub_type： 杂志文章
doi：10.1016/j.annepidem.2016.06.009
更新日期：2016-08-01 00:00:00
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journal_title：Annals of epidemiology
pub_type： 杂志文章
doi：10.1016/s1047-2797(99)00020-4
更新日期：1999-10-01 00:00:00
abstract：PURPOSE:Understanding how to mitigate the present black-white obesity disparity in the United States is a complex issue, stemming from a multitude of intertwined causes. An appropriate but underused approach to guiding policy approaches to this problem is to account for this complexity using simulation modeling. METHO...
journal_title：Annals of epidemiology
pub_type： 杂志文章
doi：10.1016/j.annepidem.2014.05.012
更新日期：2014-08-01 00:00:00
abstract：:Intervention studies are now viewed as a useful and necessary approach to understanding the relation between nutrition and cancer. Over 20 such studies have been initiated in the past 7 years. Foreign countries may be an attractive site for such investigations, mainly because of desirable population characteristics su...
journal_title：Annals of epidemiology
pub_type： 杂志文章
doi：10.1016/1047-2797(90)90010-p
更新日期：1990-12-01 00:00:00
abstract：:A population-based, case-control study of sporadic salmonellosis was conducted in 1988 and 1989 in four northern California counties. The study included 120 patients and 265 control subjects. Conditional logistic regression analysis (adjusted for age) revealed that patients were more likely to consume undercooked chic...
journal_title：Annals of epidemiology
pub_type： 杂志文章
doi：10.1016/1047-2797(92)90013-g
更新日期：1992-09-01 00:00:00
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journal_title：Annals of epidemiology
pub_type： 杂志文章
doi：10.1016/j.annepidem.2018.10.010
更新日期：2019-01-01 00:00:00
abstract：:Childhood obesity is a serious public health problem resulting from energy imbalance (when the intake of energy is greater than the amount of energy expended through physical activity). Numerous health authorities have identified policy interventions as promising strategies for creating population-wide improvements in...
journal_title：Annals of epidemiology
pub_type： 杂志文章
doi：10.1016/j.annepidem.2010.03.001
更新日期：2010-06-01 00:00:00
