Abstract:
:Transmission-ratio distortion is a departure from a 1:1 segregation of alleles in the gametes of a heterozygous individual. The so-called driving allele is strongly selected regardless of its effect on the fitness of the carrying individual. It may then have an important impact on neutral polymorphism due to the genetic hitchhiking effect. We study this hitchhiking effect in the case of true meiotic drive in autosomes and show that it is more dependent on the recombination rate than in the classical case of a gene positively selected at the organism level.
journal_name
Geneticsjournal_title
Geneticsauthors
Chevin LM,Hospital Fdoi
10.1534/genetics.105.052977subject
Has Abstractpub_date
2006-07-01 00:00:00pages
1829-32issue
3eissn
0016-6731issn
1943-2631pii
genetics.105.052977journal_volume
173pub_type
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