Small bowel haemorrhage due to cytomegalovirus vasculitis.

abstract：:It is well known that chronic encephalopathy may be a major complication after the establishment of a surgical portal caval shunt for an episode of variceal haemorrhage. In an effort to minimise this problem Warren and colleagues developed the distal splenorenal shunt where the portal and mesenteric blood flow to the ...

journal_title：Gut

authors： Bleasel AF,Waugh RC,McCaughan GW

更新日期：1989-10-01 00:00:00

abstract：:Lymphocytes obtained after enzymatic digestion of intestinal biopsies from patients with coeliac disease were examined for the presence of gliadin specific antibody secreting cells by means of the ELISPOT technique. This technique permits enumeration of gliadin antibody secreting immunocytes, differentiated with regar...

journal_title：Gut

authors： Lycke N,Kilander A,Nilsson LA,Tarkowski A,Werner N

更新日期：1989-01-01 00:00:00

abstract：:This paper describes opacification and identification of two surgically constructed pancreatico-jujunal shunts. A fibreoptic panendoscope was used with retrograde injection via the ampulla of Vater (ERCP). This procedure makes possible more accurate anatomical evaluation and so more precise clinical appraisal of both...

journal_title：Gut

authors： Miller EW,Goldberg HI,Goldberg SB,Shapiro H

更新日期：1976-06-01 00:00:00

abstract：:The extent to which monitoring breath hydrogen excretion provides information concerning the entry of the residues of a solid test meal into the colon was investigated in 89 normal subjects, and 11 patients with the irritable bowel syndrome. The profile of breath hydrogen concentration showed an early peak, that occur...

journal_title：Gut

authors： Read NW,Al-Janabi MN,Bates TE,Holgate AM,Cann PA,Kinsman RI,McFarlane A,Brown C

更新日期：1985-08-01 00:00:00

abstract：:Daytime intragastric pH, fasting and meal stimulated serum gastrin and nocturnal acid output were studied in eight male duodenal ulcer patients before, during and two days after completing nizatidine 300 mg nocte (20:00 h) for four weeks. Median nocturnal acid output (mmol/10 h) decreased during treatment to 11.6 (ran...

journal_title：Gut

authors： Fullarton GM,McLauchlan G,Macdonald A,Crean GP,McColl KE

更新日期：1989-04-01 00:00:00

abstract：OBJECTIVE:In treating patients with inflammatory bowel disease (IBD), how concomitant medications influence the response to infliximab is largely unexplored. We aim to evaluate whether proton pump inhibitors (PPIs) affect the response to infliximab therapy in patients with IBD. DESIGN:Patient-level data of adult patie...

journal_title：Gut

authors： Lu TX,Dapas M,Lin E,Peters T,Sakuraba A

更新日期：2020-12-17 00:00:00

abstract：OBJECTIVE:To examine the relationship between Mediterranean diet and risk of later-onset Crohn's disease (CD) or ulcerative colitis (UC). DESIGN:We conducted a prospective cohort study of 83 147 participants (age range: 45-79 years) enrolled in the Cohort of Swedish Men and Swedish Mammography Cohort. A validated food...

journal_title：Gut

authors： Khalili H,Håkansson N,Chan SS,Chen Y,Lochhead P,Ludvigsson JF,Chan AT,Hart AR,Olén O,Wolk A

更新日期：2020-09-01 00:00:00

abstract：OBJECTIVES:Recent studies using the lactulose hydrogen breath test (LHBT) suggest most patients with irritable bowel syndrome (IBS) have small intestinal bacterial overgrowth (SIBO). However, the validity of the LHBT has been questioned, particularly as this test could reflect changes in oro-caecal transit. Therefore, ...

journal_title：Gut

authors： Yu D,Cheeseman F,Vanner S

更新日期：2011-03-01 00:00:00

abstract：:In a prospective survey positive antimitochondrial antibodies have been detected in 69/4200 (1.64%) of all sera submitted to a routine immunology laboratory. Of the 69, only nine patients had uniquivocal primary biliary cirrhosis, six others had chronic active hepatitis, 10 had abnormal liver function tests without ev...

journal_title：Gut

authors： Triger DR,Charlton CA,Ward AM

更新日期：1982-10-01 00:00:00

abstract：BACKGROUND:Cholangiocarcinoma cells express high levels of the antiapoptotic proteins Bcl-X(L) and Mcl-1 and are markedly chemo- and radioresistant. Mitochondria have emerged as central players in apoptosis. Antiapoptotic members of the Bcl-2 protein family localise to the outer mitochondrial membrane and regulate mito...

journal_title：Gut

authors： Okaro AC,Fennell DA,Corbo M,Davidson BR,Cotter FE

更新日期：2002-10-01 00:00:00

abstract：OBJECTIVE:Lesogaberan (AZD3355) is a novel γ-aminobutyric acid B-type receptor agonist designed to treat gastro-oesophageal reflux disease (GERD) by inhibiting transient lower oesophageal sphincter relaxations. A randomised, double-blind, placebo-controlled, multi-centre phase IIb study was performed to assess the effi...

journal_title：Gut

authors： Shaheen NJ,Denison H,Björck K,Karlsson M,Silberg DG

更新日期：2013-09-01 00:00:00

abstract：OBJECTIVE:Metabolic syndrome (MetS) arises from complex interactions between host genetic and environmental factors. Although it is now widely accepted that the gut microbiota plays a crucial role in host metabolism, current knowledge on the effect of host genetics on specific gut microbes related to MetS status remain...

journal_title：Gut

authors： Lim MY,You HJ,Yoon HS,Kwon B,Lee JY,Lee S,Song YM,Lee K,Sung J,Ko G

更新日期：2017-06-01 00:00:00

abstract：BACKGROUND:Caroli's disease is a rare congenital disorder characterised by cystic dilatation of the intrahepatic bile ducts and an increased risk of cholangiocellular carcinoma. The cause is unknown, but occasional familial clustering suggests that some cases are inherited, in particular when occurring in association w...

journal_title：Gut

authors： Parada LA,Hallén M,Hägerstrand I,Tranberg KG,Johansson B

更新日期：1999-11-01 00:00:00

abstract：BACKGROUND:5-Lipoxygenase products play a part in inflammatory response. AIMS:The effect of intracolonic administration of zileuton (a 5-lipoxygenase inhibitor) on colonic damage and eicosanoid local release was assessed in a rat model of colitis. METHODS:Ninety rats with trinitrobenzenesulphonic acid induced colitis...

journal_title：Gut

authors： Bertrán X,Mañé J,Fernández-Bañares F,Castellá E,Bartolí R,Ojanguren I,Esteve M,Gassull MA

更新日期：1996-06-01 00:00:00

abstract：:The effects of the methyl ester analogue of prostaglandin E1, misoprostol, on gastric epithelial cell proliferation were investigated in six dogs given 300 micrograms/kg/day of misoprostol orally for 11 weeks and in six control dogs given placebo for 11 weeks. Misoprostol treatment resulted in a 36% increase in stomac...

journal_title：Gut

authors： Goodlad RA,Madgwick AJ,Moffatt MR,Levin S,Allen JL,Wright NA

更新日期：1989-03-01 00:00:00

abstract：OBJECTIVE:The risk of colorectal cancer after a previous negative colonoscopy is very low. Nevertheless, interval cancers occur. We aimed to assess the characteristics and predictors of interval cancers after negative colonoscopy. METHODS:A population-based case-control study was conducted in Southern Germany in 2003-...

journal_title：Gut

authors： Brenner H,Chang-Claude J,Seiler CM,Hoffmeister M

更新日期：2012-11-01 00:00:00

abstract：:Previous experimental studies suggest that bile salt-induced colonic fluid secretion is mediated by adenosine 3':5'-phosphate (cyclic AMP). Two biopsy specimens of colonic mucosa were obtained endoscopically before and after different periods of therapy (five, 10, or 15 days), from each of 21 patients receiving chenod...

journal_title：Gut

authors： Corazza GR,Ciccarelli R,Caciagli F,Gasbarrini G

更新日期：1979-06-01 00:00:00

abstract：OBJECTIVE:Hepatocellular adenomas (HCAs) classically develop in women who are taking oral contraceptives and have a risk of malignant transformation into hepatocellular carcinoma (HCC). HCA with malignant transformation is, however, an ill-defined entity thought to be an anecdotic pathway to HCC. The objective of this ...

journal_title：Gut

authors： Farges O,Ferreira N,Dokmak S,Belghiti J,Bedossa P,Paradis V

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND AND AIMS:While patients with Barrett's oesophagus develop oesophageal adenocarcinoma more frequently than the general population, it has controversially been suggested that gastro-oesophageal reflux (GORD) itself is a more important determinant of risk. In order to assess the validity of this suggestion, we ...

journal_title：Gut

authors： Solaymani-Dodaran M,Logan RF,West J,Card T,Coupland C

更新日期：2004-08-01 00:00:00

abstract：BACKGROUND:Some cirrhotic patients with tense ascites who undergo paracentesis develop a circulatory dysfunction syndrome, manifested by an increase in plasma renin activity. Recently, a significant inverse correlation between postparacentesis changes in plasma renin activity and systemic vascular resistance has been d...

journal_title：Gut

authors： Cabrera J,Falcón L,Gorriz E,Pardo MD,Granados R,Quinones A,Maynar M

更新日期：2001-03-01 00:00:00

abstract：BACKGROUND AND AIMS:The incidence of oesophageal adenocarcinoma (OAC) has been increasing rapidly with a dismal survival rate of less than 20%. Understanding the genomic aberrations and biology of this cancer may enhance disease interventions. This study aimed to use genome-wide genomic and expression data to enhance t...

journal_title：Gut

authors： Goh XY,Rees JR,Paterson AL,Chin SF,Marioni JC,Save V,O'Donovan M,Eijk PP,Alderson D,Ylstra B,Caldas C,Fitzgerald RC

更新日期：2011-10-01 00:00:00

abstract：:Seventeen patients with proven systemic sclerosis had a peroral jejunal biopsy performed. Four biopsies were regarded as showing abnormalities, which were mostly confined to the deeper structures, although in two there was a minimal degree of villous atrophy without epithelial cell changes. Passive intestinal permeabi...

journal_title：Gut

authors： Cobden I,Rothwell J,Axon AT,Dixon MF,Lintott DJ,Rowell NR

更新日期：1980-04-01 00:00:00

abstract：:We have studied B-lymphocyte function in 39 patients with Crohn's disease and 35 normal individuals using a reverse haemolytic plaque assay as the effector system. Ten patients had active Crohn's disease, the others being in an inactive state of the disease. Compared with normal individuals, the Crohn's disease patien...

journal_title：Gut

authors： Sieber G,Herrmann F,Zeitz M,Teichmann H,Rühl H

更新日期：1984-11-01 00:00:00

abstract：OBJECTIVE:Intraluminal acid evokes reflex contraction of oesophageal longitudinal smooth muscle (LSM) and consequent oesophageal shortening. This reflex may play a role in the pathophysiology of oesophageal pain syndromes and hiatus hernia formation. The aim of the current study was to elucidate further the mechanisms ...

journal_title：Gut

authors： Paterson WG,Miller DV,Dilworth N,Assini JB,Lourenssen S,Blennerhassett MG

更新日期：2007-10-01 00:00:00

abstract：OBJECTIVE:The number of colonoscopies required to reach competency is not well established. The primary aim of this study was to determine the number of colonoscopies trainees need to perform to attain competency, defined by a caecal intubation rate (CIR) ≥90%. As competency depends on completion, we also investigated ...

journal_title：Gut

authors： Ward ST,Mohammed MA,Walt R,Valori R,Ismail T,Dunckley P

更新日期：2014-11-01 00:00:00

abstract：BACKGROUND:The aim of the study was to test the hypothesis that in the fasting state, proximal intestinal HCO3- absorption, which depends on villus Na+/H+ exchanger activity, is tonically inhibited by a cholinergic atropine sensitive mechanism. SUBJECTS:The experiments were performed in 34 healthy volunteers and in ei...

journal_title：Gut

authors： Mellander A,Sjövall H

更新日期：1999-03-01 00:00:00

abstract：BACKGROUND:Pyoderma gangrenosum (PG) is a chronic ulcerating skin condition that often occurs in association with inflammatory bowel disease. There have been a number of reports of PG responding to infliximab, a monoclonal antibody against tumour necrosis factor alpha. AIM:In the first randomised placebo controlled tr...

journal_title：Gut

authors： Brooklyn TN,Dunnill MG,Shetty A,Bowden JJ,Williams JD,Griffiths CE,Forbes A,Greenwood R,Probert CS

更新日期：2006-04-01 00:00:00

abstract：:Symptom assessment, by structured interview or questionnaire, is central to the diagnosis of gastro-oesophageal reflux disease (GORD). However, empiric support for the diagnostic utility of reflux symptom measures is lacking. Reliable reflux symptom questionnaires have been developed with content validity. These quest...

journal_title：Gut

authors： Shaw M

更新日期：2004-05-01 00:00:00

abstract：BACKGROUND:Patients with liver cirrhosis are at increased risk of serious bacterial infections carrying a high case fatality rate. Case reports have suggested an association between liver cirrhosis and pyogenic liver abscess. AIMS:To estimate the risk and case fatality rate of pyogenic liver abscess in Danish patients...

journal_title：Gut

authors： Mølle I,Thulstrup AM,Vilstrup H,Sørensen HT

更新日期：2001-02-01 00:00:00

abstract：BACKGROUND/AIM:To examine the risks for hepatocellular carcinoma (HCC) with respect to hepatitis B virus (HBV) genotypes, specific viral mutations (MT), serum HBV DNA levels, and cirrhosis. METHODS:HBV genotypes, 1653/1753/core promoter (CP)/precore MT and HBV DNA levels were determined in 248 HBV patients with HCC an...

journal_title：Gut

authors： Yuen MF,Tanaka Y,Shinkai N,Poon RT,But DY,Fong DY,Fung J,Wong DK,Yuen JC,Mizokami M,Lai CL

更新日期：2008-01-01 00:00:00