Configuration Interaction in the Calculation of Oscillatory and Rotatory Intensities of Nonplanar pi-Electronic Systems.

abstract：:Two RNA fractions have been isolated and purified from both oncogenic and nononcogenic strains of Agrobacterium tumefaciens. Both RNAs are capable of inducing the formation of transplantable tumors when introduced at wound sites in stems of Datura stramonium plants. One of these RNA fractions was found to be bound to ...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Beljanski M,Aaron-da Cunha MI,Beljanski MS,Manigault P,Bourgarel P

更新日期：1974-05-01 00:00:00

abstract：:Vanadyl sulfate and sodium orthovanadate in the concentration range between 5 and 50 microM are shown to be mitogenic for quiescent cultures of Swiss mouse 3T3 and 3T6 cells. The compounds caused a striking shift in the dose-response for the effect of serum on [3H]thymidine incorporation and DNA synthesis. In the abse...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Smith JB

更新日期：1983-10-01 00:00:00

abstract：:We examine how the polypeptide chain in protein crystal structures exploits the multivalent hydrogen-bonding potential of bound water molecules. This shows that multiple interactions with a single water molecule tend to occur locally along the chain. A distinctive internal-coordinate representation of the local water-...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Robert CH,Ho PS

更新日期：1995-08-01 00:00:00

abstract：:The biological realm has inherited symmetries from the physicochemical realm, but with the increasing complexity at higher phenomenological levels of life, some inherited symmetries are broken while novel symmetries appear. These symmetries are of two types, structural and operational. Biological novelties result from...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： García-Bellido A

更新日期：1996-12-10 00:00:00

abstract：:Developing autoreactive B cells edit their B cell antigen receptor (BCR) in the bone marrow and are clonally deleted when they fail to reexpress an innocent BCR. Here, inducible Cre-loxP-mediated gene inversion is used to change the specificity of the BCR on mature IgM+ IgD+ B cells in vivo to address the fate of lymp...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Lam KP,Rajewsky K

更新日期：1998-10-27 00:00:00

abstract：:Limited trypsinization of the fatty acid synthetase multienzyme complex from rat mammary gland results in the release of a protein, molecular weight 32,000, with thioesterase activity. The other components of the multienzyme complex--the acyl carrier protein, acetyl and malonyl transferases, condensing enzyme, keto re...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Smith S,Agradi E,Libertini L,Dileepan KN

更新日期：1976-04-01 00:00:00

abstract：:Measurements of submicron particles by Fourier transform infrared spectroscopy in 14 campaigns in North America, Asia, South America, and Europe were used to identify characteristic organic functional group compositions of fuel combustion, terrestrial vegetation, and ocean bubble bursting sources, each of which often ...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Russell LM,Bahadur R,Ziemann PJ

更新日期：2011-03-01 00:00:00

abstract：:We applied the directional tag PCR subtractive hybridization method to construct a rat hypothalamic cDNA library from which cerebellar and hippocampal sequences had been depleted, enriching 20-30-fold for sequences expressed selectively in the hypothalamus. We studied a sample of 94 clones selected for enrichment in t...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Gautvik KM,de Lecea L,Gautvik VT,Danielson PE,Tranque P,Dopazo A,Bloom FE,Sutcliffe JG

更新日期：1996-08-06 00:00:00

abstract：:A DNA-dependent RNA polymerase has been purified from disrupted virions of the Escherichia coli bacteriophage N4. The RNA polymerase is phage-coded and is required for class I N4 RNA synthesis, which is defined as RNA synthesized in vivo in the absence of post-infection protein synthesis. A polypeptide of molecular we...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Falco SC,Zivin R,Rothman-Denes LB

更新日期：1978-07-01 00:00:00

abstract：:Scholander and his coworkers have described in These Proceedings several experiments in which the osmotic pressure exerted by colloidal particles appears to be altered when the particles are subject to an external force; they interpret the experiments as showing that the traditional explanation of osmotic pressure is ...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Hobbie RK

更新日期：1974-08-01 00:00:00

abstract：:In choanoflagellates, the closest living relatives of animals, multicellular rosette development is regulated by environmental bacteria. The simplicity of this evolutionarily relevant interaction provides an opportunity to identify the molecules and regulatory logic underpinning bacterial regulation of development. We...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Woznica A,Cantley AM,Beemelmanns C,Freinkman E,Clardy J,King N

更新日期：2016-07-12 00:00:00

abstract：:Most marine organisms disperse via ocean currents as larvae, so it is often assumed that larval-stage duration is the primary determinant of geographic range size. However, empirical tests of this relationship have yielded mixed results, and alternative hypotheses have rarely been considered. Here we assess the relati...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Luiz OJ,Allen AP,Robertson DR,Floeter SR,Kulbicki M,Vigliola L,Becheler R,Madin JS

更新日期：2013-10-08 00:00:00

abstract：:Genetic manipulation of nitrogenase and key glutamate-forming enzymes can provide mutants that excrete fixed N2 as NH4+. A derepressed N2 fxation mutant (SK-24) has been isolated , which excretes up to 20.2 mumol of fixed N2 as NH4+ per mg of cell protein in 24 hr at room temperature. Biochemical analysis shows that t...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Shanmugam KT,Valentine RC

更新日期：1975-01-01 00:00:00

abstract：:Cytotactin is an extracellular matrix protein that is dynamically and transiently expressed in a place-dependent fashion during development by glial cells, fibroblasts, and several other cell types. In the present study, the effects of cytotactin on cell proliferation were examined in fibroblastic cells in culture. NI...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Crossin KL

更新日期：1991-12-15 00:00:00

abstract：:Blindsight is a phenomenon in which human patients with damage to striate cortex deny any visual sensation in the resultant visual field defect but can nonetheless detect and localize stimuli when persuaded to guess. Although monkeys with striate lesions have also been shown to exhibit some residual vision, it is not ...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Moore T,Rodman HR,Repp AB,Gross CG

更新日期：1995-08-29 00:00:00

abstract：:Eradication of an invasive species can provide significant environmental, economic, and social benefits, but eradication programs often fail. Constant and careful monitoring improves the chance of success, but an invasion may seem to be in decline even when it is expanding in abundance or spatial extent. Determining w...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Keith JM,Spring D

更新日期：2013-08-13 00:00:00

abstract：:Rod signals in the mammalian retina are thought to reach ganglion cells over the circuit rod-->rod depolarizing bipolar cell-->AII amacrine cell-->cone bipolar cells-->ganglion cells. A possible alternative pathway involves gap junctions linking the rods and cones, the circuit being rod-->cone-->cone bipolar cells-->g...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： DeVries SH,Baylor DA

更新日期：1995-11-07 00:00:00

abstract：:The genes encoding the variable (V) region of the B-cell antigen receptor (BCR) are assembled from V, D (diversity), and J (joining) elements through a RAG-mediated recombination process that relies on the recognition of recombination signal sequences (RSSs) flanking the individual elements. Secondary V(D)J rearrangem...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Sun A,Novobrantseva TI,Coffre M,Hewitt SL,Jensen K,Skok JA,Rajewsky K,Koralov SB

更新日期：2015-02-03 00:00:00

abstract：:Factor XI (plasma thromboplastin antecedent) deficiency is a blood coagulation abnormality occurring in high frequency in Ashkenazi Jews. Three independent point mutations that result in a blood coagulation abnormality have been identified in the factor XI gene of six unrelated Ashkenazi patients. These mutations eith...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Asakai R,Chung DW,Ratnoff OD,Davie EW

更新日期：1989-10-01 00:00:00

abstract：:Nonhomologous integration vectors have been used to demonstrate the feasibility of insertional mutagenesis in haploid tachyzoites of the protozoan parasite Toxoplasma gondii. Mutant clones resistant to 5-fluorouracil were identified at a frequency of approximately 10(-6) (approximately 2 x 10(-5) of the stable transfo...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Donald RG,Roos DS

更新日期：1995-06-06 00:00:00

abstract：:Intermolecular electronic coupling dictates the optical properties of molecular aggregate systems. Of particular interest are photosynthetic pigment-protein complexes that absorb sunlight then efficiently direct energy toward the photosynthetic reaction center. Two-dimensional (2D) ultrafast spectroscopy has been used...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Read EL,Engel GS,Calhoun TR,Mancal T,Ahn TK,Blankenship RE,Fleming GR

更新日期：2007-09-04 00:00:00

abstract：:The one-sided multipliers of an operator space X are a key to "latent operator algebraic structure" in X. We begin with a survey of these multipliers, together with several of the applications that they have had to operator algebras. We then describe several new results on one-sided multipliers, and new applications, ...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Blecher DP,Zarikian V

更新日期：2004-01-20 00:00:00

abstract：:The clinical severity of the neurodegenerative disorder spinal muscular atrophy (SMA) is dependent on the levels of functional Survival Motor Neuron (SMN) protein. Consequently, current strategies for developing treatments for SMA generally focus on augmenting SMN levels. To identify additional potential therapeutic a...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Sen A,Dimlich DN,Guruharsha KG,Kankel MW,Hori K,Yokokura T,Brachat S,Richardson D,Loureiro J,Sivasankaran R,Curtis D,Davidow LS,Rubin LL,Hart AC,Van Vactor D,Artavanis-Tsakonas S

更新日期：2013-06-25 00:00:00

abstract：:We have carried out a study of large malignant skin tumors (squamous cell carcinomas) and other lesions in hairless mice (groups of 38-45) intermittently exposed to ultraviolet light over a period of 15 weeks, beginning when the mice were about 10 weeks old. The several groups were given a standard diet with 0%, 0.3%,...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Dunham WB,Zuckerkandl E,Reynolds R,Willoughby R,Marcuson R,Barth R,Pauling L

更新日期：1982-12-01 00:00:00

abstract：:A dynamical theory for the evolution of the genetic code is presented, which accounts for its universality and optimality. The central concept is that a variety of collective, but non-Darwinian, mechanisms likely to be present in early communal life generically lead to refinement and selection of innovation-sharing pr...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Vetsigian K,Woese C,Goldenfeld N

更新日期：2006-07-11 00:00:00

abstract：:Employing a cell-free chromatin transcription system that recapitulates progesterone receptor (PR)-mediated transcription in vivo, we have investigated further the coactivator functions of steroid receptor coactivator-1 (SRC-1) in terms of its functional domains as well as cooperation with other coactivators in PR tra...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Liu Z,Wong J,Tsai SY,Tsai MJ,O'Malley BW

更新日期：2001-10-23 00:00:00

abstract：:Small solutes affect protein and nucleic acid processes because of favorable or unfavorable chemical interactions of the solute with the biopolymer surface exposed or buried in the process. Large solutes also exclude volume and affect processes where biopolymer molecularity and/or shape changes. Here, we develop an an...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Knowles DB,LaCroix AS,Deines NF,Shkel I,Record MT Jr

更新日期：2011-08-02 00:00:00

abstract：:Gaseous HCl generated from a variety of sources is ubiquitous in both outdoor and indoor air. Oxides of nitrogen (NO(y)) are also globally distributed, because NO formed in combustion processes is oxidized to NO(2), HNO(3), N(2)O(5) and a variety of other nitrogen oxides during transport. Deposition of HCl and NO(y) o...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Raff JD,Njegic B,Chang WL,Gordon MS,Dabdub D,Gerber RB,Finlayson-Pitts BJ

更新日期：2009-08-18 00:00:00

abstract：:India's northward flight and collision with Asia was a major driver of global tectonics in the Cenozoic and, we argue, of atmospheric CO(2) concentration (pCO(2)) and thus global climate. Subduction of Tethyan oceanic crust with a carpet of carbonate-rich pelagic sediments deposited during transit beneath the high-pro...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Kent DV,Muttoni G

更新日期：2008-10-21 00:00:00

abstract：:During exercise, increased energy demands are met by increased glucose production that occurs simultaneously with the increased glucose uptake. We had previously observed that, during exercise, metabolic clearance rate of glucose (MCR) increases markedly in normal, but only marginally in poorly controlled diabetic dog...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Miles PD,Yamatani K,Lickley HL,Vranic M

更新日期：1991-02-15 00:00:00