Glucosamine oligomers: 2. N.m.r. studies on a DP3.


:This paper concerns the characterization of the chemical structure of a DP3 glucosamine oligomer. The assignments of nearly all protons are reported. Variations of 1H chemical shifts with pD and temperature are correlated to the pKa of amino groups, and not with substantial conformational changes.


Int J Biol Macromol


Domard A,Gey C,Taravel F





Has Abstract


1991-04-01 00:00:00














  • Natural hepatocyte growth factor (HGF) from human serum and a bound form of recombinant HGF with heparan sulfate are indistinguishable in their physicochemical properties.

    abstract::Natural hepatocyte growth factor (nHGF) purified from human serum showed a difference in molecular mass (Mr) between SDS PAGE (76-90 kDa) and gel filtration chromatography on a Sephadex G-200 column (> 200 kDa), whereas nHGF or recombinant HGF (rHGF) from cell culture medium did almost the same Mr (74-100 kDa). A boun...

    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章


    authors: Yano K,Tsuda E,Ueda M,Higashio K

    更新日期:1998-10-01 00:00:00

  • Heparin based polyurethanes: A state-of-the-art review.

    abstract::Polyurethanes (PUs) are considered currently as one of the established bio compatible and blood compatible biomaterials offering tremendous structure-property relationship. But few limitations such as low resistance to micro-emboli and thrombi are still associated with these biomaterials that restricted their applicat...

    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章,评审


    authors: Zia F,Zia KM,Zuber M,Tabasum S,Rehman S

    更新日期:2016-03-01 00:00:00

  • Inhibitory effect on HT-29 colon cancer cells of a water-soluble polysaccharide obtained from highland barley.

    abstract::A water-soluble polysaccharide (BP-1) was obtained from highland barley (Hordeum vulgare L.) by hot water extraction and purification of sepharose column chromatography. BP-1 had an average molecular weight of about 6.7×104Da and was composed of glucose (Glc), xylose (Xyl), arabinose (Ara) and rhamnose (Rha) with a re...

    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章


    authors: Cheng D,Zhang X,Meng M,Han L,Li C,Hou L,Qi W,Wang C

    更新日期:2016-11-01 00:00:00

  • New crosslinked-chitosan graft poly(N-vinyl-2-pyrrolidone) for the removal of Cu(II) ions from aqueous solutions.

    abstract::Crosslinked chitosan beads were grafted with N-vinyl-2-pyrrolidone (NVP) using ammonium persulfate (APS) as free radical initiator. Important variables on graft copolymerization such as temperature, reaction time, concentration of initiator and concentration of monomer were optimized. The results revealed optimum cond...

    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章


    authors: Sutirman ZA,Sanagi MM,Abd Karim J,Abu Naim A,Wan Ibrahim WA

    更新日期:2018-02-01 00:00:00

  • Chitosan hydrogel in combination with marine peptides from tilapia for burns healing.

    abstract::The purpose of this study was to develop a promising burns dressing. Chiosan (CS) has been widely used as biomaterials, in combination with marine peptides (MPs) extracted from seawater cultured Tilapia, the newly developed material Chitosan-Marine Peptides hydrogels (CSMP) in this study showed antibacterial activity,...

    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章


    authors: Ouyang QQ,Hu Z,Lin ZP,Quan WY,Deng YF,Li SD,Li PW,Chen Y

    更新日期:2018-06-01 00:00:00

  • Oriented covalent immobilization of recombinant protein A on the glutaraldehyde activated agarose support.

    abstract::High IgG-binding capacity of protein A affinity chromatography is crucial to its application in the antibody purification and autoantibody-associated disease treatment. An oriented immobilization strategy was used to covalently conjugate the recombinant protein A (rSpA) on the glutaraldehyde activated agarose. By cont...

    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章


    authors: Wang Y,Zhang X,Han N,Wu Y,Wei D

    更新日期:2018-12-01 00:00:00

  • Morphological and thermal studies of chitin-curcumin blends derived polyurethanes.

    abstract::The present study describes a novel ecofriendly series of chitin/curcumin/1,4-butane diol (BDO) blend derived polyurethanes (PUs), using hydroxy terminated polybutadiene (HTPB) and hexamethylene diisocyanate (HDI) along with different mole ratio of chitin, curcumin and BDO. The structural and morphological elucidation...

    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章


    authors: Mahmood K,Zia KM,Zuber M,Tabasum S,Rehman S,Zia F,Noreen A

    更新日期:2017-12-01 00:00:00

  • Phosphorylated Codonopsis pilosula polysaccharide could inhibit the virulence of duck hepatitis A virus compared with Codonopsis pilosula polysaccharide.

    abstract::To screen effective anti-duck hepatitis A virus (DHAV) drugs, we applied STMP-STPP method to prepare phosphorylated Codonopsis pilosula polysaccharide (pCPPS), the phosphorylation-modified product of Codonopsis pilosula polysaccharide (CPPS). The IR spectrum and field emission scanning electron microscope (FE-SEM) wer...

    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章


    authors: Ming K,Chen Y,Yao F,Shi J,Yang J,Du H,Wang X,Wang Y,Liu J

    更新日期:2017-01-01 00:00:00

  • Molecular modification of native coffee polysaccharide using subcritical water treatment: Structural characterization, antioxidant, and DNA protecting activities.

    abstract::Polysaccharides are an abundant resource in coffee beans and have proved to show numerous bioactivities. Despite their abundance, their activities are not always satisfactory mostly due to their structure and large molecular size. Molecular modifications of native polysaccharides can overcome this problem. In this stu...

    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章


    authors: Getachew AT,Chun BS

    更新日期:2017-06-01 00:00:00

  • Promising alternative gum: Extraction, characterization, and oxidation of the galactomannan of Cassia fistula.

    abstract::Galactomannan extracted from Cassia fistula seed endosperm present little data related to the its structural characterization. This study reports the chemical characterization of the galactomannan from Cassia fistula (CF) and their oxidized derivatives. The extracted CF presented a yield of 26.5% (w/w) and the intrins...

    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章


    authors: da Silva LM,Araújo LFS,Alvez RC,Ono L,Sá DAT,da Cunha PLR,Monteiro de Paula RC,Maciel JS

    更新日期:2020-12-15 00:00:00

  • Tyr320 is a molecular determinant of the catalytic activity of β-glucosidase from Neosartorya fischeri.

    abstract::β-Glucosidases (BGL) are key members of the cellulase enzyme complex that determine efficiency of lignocellulosic biomass degradation, which have shown great functional importance to many biotechnological systems. A previous reported BGL from Neosartorya fischeri (NfBGL) showed much higher activity than other BGLs. Sc...

    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章


    authors: Shanmugam R,Kim IW,Tiwari MK,Gao H,Mardina P,Das D,Kumar A,Jeya M,Kim SY,Kim YS,Lee JK

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  • Cross-linked chitosan in nano and bead scales as drug carriers for betamethasone and tetracycline.

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    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章


    authors: Taghizadeh MT,Ashassi-Sorkhabi H,Afkari R,Kazempour A

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    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章


    authors: Lin D,Yang Y,Wang J,Yan W,Wu Z,Chen H,Zhang Q,Wu D,Qin W,Tu Z

    更新日期:2020-07-01 00:00:00

  • Oral administration of chitin and chitosan prevents peanut-induced anaphylaxis in a murine food allergy model.

    abstract::Peanut allergy is IgE-mediated type-I hypersensitivity, and T helper 2 cytokines are central to those pathogenesis. We investigated the effects of the administration of chitin and chitosan on peanut-induced hypersensitivities in mouse food allergy models. Chitin and chitosan protected mice against peanut-induced anaph...

    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章


    authors: Bae MJ,Shin HS,Kim EK,Kim J,Shon DH

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  • An investigation on biosorption of nitrate from water by chitosan based organic-inorganic hybrid biocomposites.

    abstract::In this study, three types of crosslinked organic-inorganic hybrid biocomposites, such as chitosan/bentonite, chitosan/titanium oxide, and chitosan/alumina (ChBT, ChTi, and ChAl respectively) were prepared and utilized for the removal of nitrate from water by batch biosorption experiments. Effects of crosslinker dose,...

    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章


    authors: Golie WM,Upadhyayula S

    更新日期:2017-04-01 00:00:00

  • Characteristics and thermodynamics of a thermostable protease from a salt-tolerant alkaliphilic actinomycete.

    abstract::An alkaline serine protease from a newly isolated salt-tolerant alkaliphilic actinomycetes, Brachystreptospora xinjiangensis OM-6 was purified with 35- and 26-fold purification and 47% and 22% yield employing two steps and one step methods, respectively. The enzyme was quite stable at 80 °C in 30% Na-glutamate with th...

    journal_title:International journal of biological macromolecules

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    authors: Gohel SD,Singh SP

    更新日期:2013-05-01 00:00:00

  • Effects of trehalose and sorbitol on the activity and structure of Pseudomonas cepacia lipase: spectroscopic insight.

    abstract::The stability of enzymes with no reduction in their catalytic activity still remains a critical issue in industrial applications. Naturally occurring osmolytes are commonly used as protein stabilizers. In this study we have investigated the effects of sorbitol and trehalose on the structural stability and activity of ...

    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章


    authors: Azizi A,Ranjbar B,Khajeh K,Ghodselahi T,Hoornam S,Mobasheri H,Ganjalikhany MR

    更新日期:2011-11-01 00:00:00

  • Antitumor evaluation of carboxymethyl chitosan based norcantharidin conjugates against gastric cancer as novel polymer therapeutics.

    abstract::Novel polymer-drug conjugates (CNC) were prepared from carboxymethyl chitosan (CMCS) and norcantharidin (NCTD) via amidation reaction and characterized by FTIR and 1H NMR spectroscopy. The aim of this study was to elucidate the antitumor efficacy of CNC on gastric cancer and the possible underlying mechanisms. The CNC...

    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章


    authors: Chi J,Jiang Z,Qiao J,Zhang W,Peng Y,Liu W,Han B

    更新日期:2019-09-01 00:00:00

  • Preparation of Thai silk fibroin/gelatin electrospun fiber mats for controlled release applications.

    abstract::This work studied the effect of preparation conditions for electrospun fiber mats of Thai silk fibroin/type B gelatin (SF/GB) for controlled release applications. The increasing in applied voltage resulted in decreased average fiber size and narrow fiber size distribution. An increasing in silk fibroin content in blen...

    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章


    authors: Okhawilai M,Rangkupan R,Kanokpanont S,Damrongsakkul S

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  • Structural characterization and neuroprotective effect of a polysaccharide from Corydalis yanhusuo.

    abstract::In the present study, we investigated the neuroprotective effects of a purified Corydalis yanhusuo polysaccharide (CYP) on Aβ (25-35)-induced neurotoxicity and explored its underlying molecular mechanisms in PC12 cells. The results showed pretreatment with CYP (25, 50, and 100 μg/ml) prior to Aβ (25-35) exposure signi...

    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章


    authors: He Y,Xu W,Qin Y

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  • Characterization of intermediate state of myoglobin in the presence of PEG 10 under physiological conditions.

    abstract::The macromolecular crowding progressively has been gaining prominence in recent years as it acts as a sword with double-edge on protein stability and folding, i.e., showing assorted results of having both stabilizing and destabilizing effects. We studied the effects of different concentrations of polyethylene glycol (...

    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章


    authors: Parray ZA,Shahid S,Ahmad F,Hassan MI,Islam A

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  • 4- Substituted sampangine derivatives: Novel acetylcholinesterase and β-myloid aggregation inhibitors.

    abstract::A series of 4- substituted sampangine derivatives (4-aminoalkylaminosampangine Ar-NH(CH2)nNR1R2) has been designed, synthesized, and tested for their ability to inhibit acetylcholinesterase (AChE), butyrylcholinesterase (BChE) and β-myloid (Aβ) aggregation. The synthetic compounds exhibited high AChE inhibitory activi...

    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章


    authors: Chen KL,Gan L,Wu ZH,Qin JF,Liao WX,Tang H

    更新日期:2018-02-01 00:00:00

  • Immobilization of indigenous holocellulase on iron oxide (Fe2O3) nanoparticles enhanced hydrolysis of alkali pretreated paddy straw.

    abstract::The holocellulase from Aspergillus niger SH3 was characterized and found to contain 125 proteins including cellulases (26), hemicellulases (21), chitinases (10), esterases (6), amylases (4) and hypothetical protein (32). The crude enzyme was immobilized on five different nanoparticles (NPs) via physical adsorption and...

    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章


    authors: Kumar A,Singh S,Tiwari R,Goel R,Nain L

    更新日期:2017-03-01 00:00:00

  • Fish collagen/alginate/chitooligosaccharides integrated scaffold for skin tissue regeneration application.

    abstract::An emerging paradigm in wound healing techniques is that a tissue-engineered skin substitute offers an alternative approach to create functional skin tissue. Here we developed a fish collagen/alginate (FCA) sponge scaffold that was functionalized by different molecular weights of chitooligosaccharides (COSs) with the ...

    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章


    authors: Chandika P,Ko SC,Oh GW,Heo SY,Nguyen VT,Jeon YJ,Lee B,Jang CH,Kim G,Park WS,Chang W,Choi IW,Jung WK

    更新日期:2015-11-01 00:00:00

  • Protein-metallodrugs interactions: Effects on the overall protein structure and characterization of Au, Ru and Pt binding sites.

    abstract::The effects of metalation process by inorganic compounds containing Au, Pt and Ru on protein structure and on conformation and flexibility of the residues involved in the metal compound binding have been here investigated by analysing 204 structures of protein/metallodrug adducts and the corresponding metal-free forms...

    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章


    authors: Loreto D,Ferraro G,Merlino A

    更新日期:2020-11-15 00:00:00

  • Myo-inositol hexasulphate and low molecular weight heparin binding to human acidic fibroblast growth factor: a calorimetric and FTIR study.

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    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章


    authors: Guzmán-Casado M,Cardenete A,Giménez-Gallego G,Parody-Morreale A

    更新日期:2001-04-12 00:00:00

  • Some biophysical applications of motional contrast in n.m.r. microscopy.

    abstract::The principal advantage of the n.m.r. imaging method lies in the specific contrasts which are available. In this work we describe the use of velocity and diffusion contrast methods in biophysical applications and at microscopic spatial resolution. In the first example, involving water-protein interactions, the relatio...

    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章


    authors: Back PJ,Coy A,Xia Y,Callaghan PT,Diamante LM,Umbach SL

    更新日期:1991-06-01 00:00:00

  • Probing the structure-function relationship of Mycobacterium leprae HSP18 under different UV radiations.

    abstract::Ultraviolet radiation, an effective sterilizing source, rapidly kills the causative organism (Mycobacterium leprae) of leprosy. But, the reasons behind this quick death are not clearly understood. Also, the impact of UV radiation on the antigen(s) which is/are responsible for the survival of this pathogen is still unk...

    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章


    authors: Chakraborty A,Nandi SK,Panda AK,Mahapatra PP,Giri S,Biswas A

    更新日期:2018-11-01 00:00:00

  • Effect of hydroxypropyl-β-cyclodextrin on the bounding of salazosulfapyridine to human serum albumin.

    abstract::The supramolecular interaction between salazosulfapyridine (SASP) and hydroxypropyl-β-cyclodextrin (HP-β-CD), as well as the influence of HP-β-CD on SASP's binding to human serum albumin (HSA), were investigated. Phase-solubility studies indicate that the HP-β-CD/SASP inclusion complex was formed at a 1:1 host-guest s...

    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章


    authors: Tang P,Tang B,Wang Q,Xu K,Xiong X,Li H

    更新日期:2016-11-01 00:00:00

  • Alginate-based nanocomposites for efficient removal of heavy metal ions.

    abstract::Cobalt ferrite nanoparticles (CF), titanate nanotubes (T), alginate (G) and their nanocomposite microparticles (CF/G and T/G) were prepared and used for efficient removal of Cu2+, Fe3+ and As3+ ions from water. The nanocomposites were characterized using field emission scanning electron microscopy (FESEM), X-ray diffr...

    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章


    authors: Esmat M,Farghali AA,Khedr MH,El-Sherbiny IM

    更新日期:2017-09-01 00:00:00