Abstract:
:Lectins are proteins capable of specific and reversible binding to mono- and/or oligosaccharides, and within this group, Legume lectins are the most studied. However, most of these studies focus on the Papilionoideae subfamily, with Caesalpinioideae and Mimosoideae lectins being significantly less explored in the literature. The Mimosoideae subfamily consists of at least 79 genera and 3275 species, but, to date, only about 14 lectins have been purified, a fact which shows the lack of studies for this group. Based on their purification protocols, as well as physicochemical and structural properties, Mimosoideae lectins are very heterogeneous. Despite the few studies, a wide variety of biological activities have been tested, including, for example, inflammatory, anticancer, antibacterial, and antifungal. In this context, the present review aims to summarize the available data regarding the purification, physicochemical and structural properties, as well as biological activities, of lectins extracted from plants of the Mimosoideae subfamily in order to bring more insight to researchers interested in further exploring the potential of these molecules.
journal_name
Int J Biol Macromoljournal_title
International journal of biological macromoleculesauthors
Cavada BS,Osterne VJS,Oliveira MV,Pinto-Junior VR,Silva MTL,Bari AU,Lima LD,Lossio CF,Nascimento KSdoi
10.1016/j.ijbiomac.2020.03.113subject
Has Abstractpub_date
2020-07-01 00:00:00pages
159-165eissn
0141-8130issn
1879-0003pii
S0141-8130(20)31467-7journal_volume
154pub_type
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