Prenatal diagnosis and multiple pregnancy.

Abstract:

:The incidence of twins, triplets, and high-order multiples has increased dramatically in the last two decades secondary to greater reliance on fertility treatments and to delayed childbearing. Offspring of a multiple gestation are at increased risk for both chromosomal and structural abnormalities. Prenatal diagnosis in these patients is challenging. Options for screening tests are limited. Invasive diagnostic procedures are complex. Likewise, physicians and patients may be faced with the dilemma of deciding how to manage discordant results. The following paper will review the unique concerns associated with prenatal diagnosis in a multiple pregnancy and the current methods of prenatal screening in these patients. Invasive prenatal diagnosis will also be explored.

journal_name

Semin Perinatol

journal_title

Seminars in perinatology

authors

Cleary-Goldman J,D'Alton ME,Berkowitz RL

doi

10.1053/j.semperi.2005.08.005

keywords:

subject

Has Abstract

pub_date

2005-10-01 00:00:00

pages

312-20

issue

5

eissn

0146-0005

issn

1558-075X

pii

S0146-0005(05)00087-X

journal_volume

29

pub_type

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